Apoptose
Os inibidores da apoptose são compostos que previnem ou retardam o processo de morte celular programada, conhecido como apoptose. Esses inibidores são vitais no estudo dos mecanismos de sobrevivência celular e são usados para investigar doenças onde a apoptose é desregulada, como câncer, distúrbios neurodegenerativos e doenças autoimunes. Ao modular a apoptose, esses inibidores podem ajudar no desenvolvimento de terapias destinadas a controlar a morte celular. Na CymitQuimica, oferecemos uma ampla seleção de inibidores da apoptose de alta qualidade para apoiar sua pesquisa em biologia celular, oncologia e áreas relacionadas.
Subcategorias de "Apoptose"
- ASK(9 produtos)
- BCL(1 produtos)
- Caspase(154 produtos)
- FOXO1(2 produtos)
- IAP(67 produtos)
- Mdm2(12 produtos)
- PD-1/PD-L1(127 produtos)
- PDK(9 produtos)
- PERK(23 produtos)
- Serina/treonina quinase(17 produtos)
- Survivina(14 produtos)
- TNF(90 produtos)
- c-RET(61 produtos)
- p53(63 produtos)
Exibir 6 mais subcategorias
Foram encontrados 6169 produtos de "Apoptose"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
PQA-18
CAS:PQA-18, an inhibitor of p21-activated kinase 2 (PAK2; IC50 = 10 nM), is derived from Ppc-1 (product number 42352) and exhibits immunosuppressive properties. It inhibits IL-2 production in Jurkat T cells induced by Concanavalin A (product number 14951) with an IC50 of 400 nM. Topically applied at 0.1%, PQA-18 reduces the severity of atopic dermatitis, serum IgE levels, and skin thickness in the NC/Nga mouse model. A lower concentration of 0.05% also decreases skin nerve fiber density in NC/Nga mice. Additionally, PQA-18 administered at 4 mg/kg improves graft survival in a rat small intestine transplantation model.Fórmula:C25H31NO4Cor e Forma:SolidPeso molecular:409.52Anti-Mouse/Human phosphorylated PD-1/CD279 Antibody (407.6G12)
Anti-Mouse/Human phosphorylated PD-1/CD279 Antibody (407.6G12) is an IgG2a, κ antibody inhibitor derived from mice, targeting phosphorylated PD-1/CD279 in both mice and humans.Cor e Forma:Odour LiquidLicaminlimab
Licaminlimab (OCS-02) is a single-chain antibody fragment targeting TNF alpha, an inflammatory cytokine.Cor e Forma:Odour LiquidBoserolimab
CAS:Boserolimab, Humanized anti-CD27 agonistic mAb, blocks CD70 binding to CD27, used for lung cancer research.Pureza:95% - 95%Cor e Forma:LiquidVonsetamig
CAS:Vonsetamig, a humanized immunoglobulin G4-kappa monoclonal antibody, targets both TNFRSF17 and CD3E. It serves as an antineoplastic agent.Cor e Forma:LiquidToripalimab
CAS:Toripalimab is a humanized anti-PD-1 monoclonal antibody used as an immune checkpoint inhibitor in research for advanced malignancies like nasopharyngeal carcinoma.Pureza:95% - 95.2% (SDS-PAGE); 96.8% (SEC-HPLC)Cor e Forma:LiquidTavolixizumab
CAS:Tavolixizumab (also known as MEDI 0562 and Tavolimab) is a human monoclonal antibody targeting TNFRSF4 (TNF receptor superfamily member 4), utilized in cancerCor e Forma:LiquidTecaginlimab
CAS:Tecaginlimab (BNT-312), an Fc-inert bispecific antibody, targets CD40/4-1BB to boost tumor immunity.Cor e Forma:LiquidSugemalimab
CAS:Sugemalimab, Anti-PD-L1 mAb, induces ADCC, for EGFR/ALK-negative metastatic NSCLC, solid tumors, and lymphoma research.Pureza:95% - 95%Cor e Forma:LiquidRosnilimab
CAS:Rosnilimab is a PD-1 agonist that inhibits T cell proliferation and depletes T cells, enabling research into inflammatory diseases.Pureza:95% - 98.9% (SDS-PAGE); 98.7% (SEC-HPLC)Cor e Forma:LiquidPeso molecular:146.57 kDaPifithrin-β
CAS:potent p53 inhibitorFórmula:C16H16N2SPureza:98%Cor e Forma:SolidPeso molecular:268.38Afimkibart
CAS:Afimkibart (PF06480605) is a humanised monoclonal antibody targeting TL1A (TNF-like Ligand 1A), which blocks TL1A-DR3 (death domain receptor 3) signalling on restrictive immune cells and fibroblasts. It can be used for inflammatory bowel disease and ulcerative colitis.Pureza:95% - 99.2% (SDS-PAGE); 95.3% (SEC-HPLC)Cor e Forma:SoildPeso molecular:146.20 kDaPucotenlimab
CAS:Pucotenlimab (HX008) is an anti-PD-1 mAb that blocks PD-1/PD-L1/2 interactions, restoring immune function against solid tumours.Pureza:95%Cor e Forma:LiquidPeso molecular:144.77 kDaTagitanlimab
CAS:Tagitanlimab, Humanized anti-PD-L1 mAb, blocks PD-L1-PD-1 interaction, for nasopharyngeal carcinoma (NPC) research.Pureza:95% - 95%Cor e Forma:LiquidAcasunlimab
CAS:Acasunlimab (GEN1046) is a bsAb that targets PD-L1 and 4-1BB, boosting T/NK cells and blocking PD-1/PD-L1 in cancer research.Cor e Forma:LiquidTuvonralimab
CAS:Tuvonralimab, a combo of anti-PD-1/IgG4 and anti-CTLA-4/IgG1 antibodies, blocks dual immune checkpoints.Pureza:95% - 95%Cor e Forma:LiquidBAY 249716
CAS:BAY 249716 stabilizes three variants of the p53 protein and shows antitubercular activity with an IC90 against Mycobacterium tuberculosis of less than 0.10 μg/mL.Fórmula:C13H9ClN4SPeso molecular:288.76Visugromab
CAS:Visugromab (CTL-002) is a monoclonal antibody that targets and neutralises GDF-15.Pureza:95% - 98.8% (SDS-PAGE); 97.5% (SEC-HPLC)Cor e Forma:LiquidPeso molecular:144.50 kDaFrataxin-IN-1
CAS:Frataxin-IN-1 inhibits the mitochondrial protein Frataxin with IC50 45 μM and is used in Friedreich’s ataxia research linked to mitochondrial defects.Fórmula:C20H23NO6Pureza:99.34%Cor e Forma:SolidPeso molecular:373.4Amantadine sulfate
CAS:Amantadine: antiviral, anti-Parkinson's, blocks NMDA receptors, boosts dopamine/norepinephrine release.Fórmula:C20H36N2O4SCor e Forma:White Fine Crystalline PowderPeso molecular:400.58
