Apoptose
Os inibidores da apoptose são compostos que previnem ou retardam o processo de morte celular programada, conhecido como apoptose. Esses inibidores são vitais no estudo dos mecanismos de sobrevivência celular e são usados para investigar doenças onde a apoptose é desregulada, como câncer, distúrbios neurodegenerativos e doenças autoimunes. Ao modular a apoptose, esses inibidores podem ajudar no desenvolvimento de terapias destinadas a controlar a morte celular. Na CymitQuimica, oferecemos uma ampla seleção de inibidores da apoptose de alta qualidade para apoiar sua pesquisa em biologia celular, oncologia e áreas relacionadas.
Subcategorias de "Apoptose"
- ASK(9 produtos)
- BCL(5 produtos)
- Caspase(151 produtos)
- FOXO1(2 produtos)
- IAP(67 produtos)
- Mdm2(12 produtos)
- PD-1/PD-L1(105 produtos)
- PDK(9 produtos)
- PERK(26 produtos)
- Serina/treonina quinase(18 produtos)
- Survivina(14 produtos)
- TNF(58 produtos)
- c-RET(61 produtos)
- p53(63 produtos)
Exibir 6 mais subcategorias
Foram encontrados 6048 produtos de "Apoptose"
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MI-3
CAS:MI-3 (Menin-MLL Inhibitor) (Menin-MLL Inhibitor) is an effective inhibitor of Menin-MLL interaction (IC50: 648 nM).Fórmula:C18H25N5S2Pureza:98.66% - 99.61%Cor e Forma:SolidPeso molecular:375.55K145
CAS:K145: Selective, oral SphK2 inhibitor, IC50 4.3 μM, Ki 6.4 μM, promotes cell apoptosis, strong antitumor effect, inactive against SphK1/other kinases.Fórmula:C18H24N2O3SPureza:98%Cor e Forma:SolidPeso molecular:348.46QM31
CAS:QM31 is a selective Apaf-1 inhibitor(inbitita formation of the apoptosome with IC50 of 7.9μM).Fórmula:C39H38Cl4N4O4Pureza:98%Cor e Forma:SolidPeso molecular:768.56Tezacitabine
CAS:Tezacitabine, a nucleoside analogue, inhibits ribonucleotide reductase, disrupts DNA replication, and induces apoptosis in tumor cells.Fórmula:C10H12FN3O4Cor e Forma:SolidPeso molecular:257.22Topoisomerase I inhibitor 3
CAS:Topoisomerase I (Compound ZML-14) inhibitor 3 induces HepG2 cell apoptosis and arrests cell cycle at G2/M phase.Fórmula:C18H14FNO3Cor e Forma:SolidPeso molecular:311.31Mutant p53 modulator-1
CAS:Mutant p53 modulator-1 inhibits cancer with p53 mutations; see patent WO2021231474A1, compound 231B.Fórmula:C27H32F4N8O2Cor e Forma:SolidPeso molecular:576.59PD-1/PD-L1-IN-29
CAS:PD-1/PD-L1-IN-29 (S4-1) is a potent inhibitor of the PD-1/PD-L1 interaction, with an IC50 value of 6.1 nM.Fórmula:C26H24N2O6Cor e Forma:SolidPeso molecular:460.48Antitumor agent-83
Antitumor agent-83 activates BAX protein, impedes tumor growth, triggers apoptosis, and is stable in vitro.Fórmula:C29H30N6O2Cor e Forma:SolidPeso molecular:494.59BMH-7
CAS:BMH-7 (Histamine H4 receptor antagonist-2) is a p53 activator, demonstrating anti-cancer activity by activating the p53 pathway.Fórmula:C20H21N5OPureza:99.71%Cor e Forma:SolidPeso molecular:347.41PHA-690509
CAS:PHA-690509 is a cyclin-dependent kinase 2 inhibitor. It potentially for the treatment of cancer.Fórmula:C17H21N3O2SPureza:98%Cor e Forma:SolidPeso molecular:331.43SMBA1
CAS:SMBA1 is a Bax agonist with antitumor activity that can induce cell cycle arrest and apoptosis in malignant glioma cells.Fórmula:C20H13NO3Pureza:99.2%Cor e Forma:SolidPeso molecular:315.32MPT0B214
CAS:MPT0B214, a potent microtubule inhibitor, disrupts tubulin polymerization and kills various cancer cells, including drug-resistant types.Fórmula:C20H20N2O5Cor e Forma:SolidPeso molecular:368.38CK2/ERK8-IN-1
CAS:TMCB inhibits CK2 (Ki: 0.25 µM), ERK8 (IC50: 0.50 µM), PIM1, DYRK1A, HIPK2 (Ki: 8.65-15.25 µM), and induces apoptosis.Fórmula:C11H9Br4N3O2Pureza:98.22%Cor e Forma:SolidPeso molecular:534.82AMPK activator 11
CAS:AMPK Activator 11 is a nanomolar potent inhibitor of cell proliferation in various colorectal carcinomas (CRCs), acting through the selective activation of AMP-Fórmula:C25H20N4O2Pureza:98%Cor e Forma:SolidPeso molecular:408.45(S)-Elobixibat
CAS:(S)-Elobixibat is the S-isomer of Elobixibat. It is an orally active inhibitor of Apical Sodium-Dependent Bile (IBAT) and can reduce LDL cholesterol, increase serum GLP-1, and promote colonic motility. This compound shows potential for treating metabolic syndrome and can be studied for constipation, dyslipidemia, non-alcoholic hepatitis, and liver tumors.Fórmula:C36H45N3O7S2Cor e Forma:SolidPeso molecular:695.89VEGFR-2-IN-23
CAS:VEGFR-2-IN-23 (11b) is a potent VEGFR-2 inhibitor with an IC50 of 0.34 nM, exhibits antitumor effects, and causes G1 cell cycle arrest.Fórmula:C22H15N5O2Cor e Forma:SolidPeso molecular:381.39Ferroptosis inducer-1
CAS:Ferroptosis inducer-1 is a Ferroptosis inducer with antitumor potential .Fórmula:C25H21ClN2O5Cor e Forma:SolidPeso molecular:464.9Penehyclidine hydrochloride
CAS:Penehyclidine hydrochloride: M1/M3 antagonist, activates NF-κB, anti-inflammatory, anticholinergic.Fórmula:C20H30ClNO2Pureza:99.79% - 99.91%Cor e Forma:SolidPeso molecular:351.91Tubulin polymerization-IN-22
CAS:Tubulin polymerization-IN-22 inhibits tubulin (IC50=8.1μM), blocks G2/M phase, and triggers apoptosis.
Fórmula:C19H16O4Cor e Forma:SolidPeso molecular:308.33NF-κB-IN-5
CAS:NF-κB-IN-5 (compound 4d) is an orally active NF-κB inhibitor.Fórmula:C23H27N3O4Cor e Forma:SolidPeso molecular:409.48
