Apoptose
Os inibidores da apoptose são compostos que previnem ou retardam o processo de morte celular programada, conhecido como apoptose. Esses inibidores são vitais no estudo dos mecanismos de sobrevivência celular e são usados para investigar doenças onde a apoptose é desregulada, como câncer, distúrbios neurodegenerativos e doenças autoimunes. Ao modular a apoptose, esses inibidores podem ajudar no desenvolvimento de terapias destinadas a controlar a morte celular. Na CymitQuimica, oferecemos uma ampla seleção de inibidores da apoptose de alta qualidade para apoiar sua pesquisa em biologia celular, oncologia e áreas relacionadas.
Subcategorias de "Apoptose"
- ASK(9 produtos)
- BCL(5 produtos)
- Caspase(151 produtos)
- FOXO1(2 produtos)
- IAP(67 produtos)
- Mdm2(12 produtos)
- PD-1/PD-L1(105 produtos)
- PDK(9 produtos)
- PERK(26 produtos)
- Serina/treonina quinase(18 produtos)
- Survivina(14 produtos)
- TNF(58 produtos)
- c-RET(61 produtos)
- p53(63 produtos)
Exibir 6 mais subcategorias
Foram encontrados 6043 produtos de "Apoptose"
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Darinaparsin
CAS:Darinaparsin, a dimethylated arsenic-glutathione compound, is cytotoxic to various cancer cells with diverse IC50 values and inhibits tumor growth in mice.Fórmula:C12H22AsN3O6SCor e Forma:SolidPeso molecular:411.31CMLD012612
CAS:CMLD012612 is a potent eukaryotic initiation factor 4A (eIF4A) inhibitor. It inhibits cell translation and is cytotoxic to NIH/3T3 cells (IC50: 2 nM).Fórmula:C31H33N3O7Pureza:98%Cor e Forma:SolidPeso molecular:559.61Apogossypolone (ApoG2)
CAS:Apogossypolone (ApoG2) is a semi-synthesized derivative of gossypol which is a nonpeptidic small molecule inhibitor targeting Bcl-2 family proteins with K iFórmula:C28H26O8Cor e Forma:SolidPeso molecular:490.5SMIP004
CAS:SMIP004 is an SKP2 E3 ligase inhibitor. SMIP004 is a cancer cell-selective apoptosis inducer of human prostate cancer cells.Fórmula:C13H19NOPureza:99.86%Cor e Forma:SolidPeso molecular:205.3AG-024322
CAS:AG-024322 is a pan-CDK inhibitor with antitumor activity, induces apoptosis, and can be used in the study of metabolic diseases.Fórmula:C23H20F2N6Pureza:98.53%Cor e Forma:SolidPeso molecular:418.44FW1256
CAS:FW1256: phenyl analog, slow H2S donor, inhibits NF-κB, induces apoptosis, anti-inflammatory, potential cancer/cardio treatment.Fórmula:C12H10NOPSCor e Forma:SolidPeso molecular:247.25RIPK1-IN-11
CAS:RIPK1-IN-11, an oral RIPK1 blocker, Kd 9.2 nM, IC50 67 nM, prevents necrosis and inflammation in cells.Fórmula:C23H24N4O4SCor e Forma:SolidPeso molecular:452.53SS28
CAS:SS28 inhibits tubulin polymerization to cause cell cycle arrest at G2/M phase.Fórmula:C18H20O3Pureza:98%Cor e Forma:SolidPeso molecular:284.35BMS-200
CAS:BMS-200 is a potent PD-1/PD-L1 interaction inhibitor with IC50 of 80 nM.Fórmula:C27H27F2NO6Cor e Forma:SolidPeso molecular:499.5STAT3-IN-3
CAS:STAT3-IN-3 is a potent and selective signal transducer inhibitor and transcription 3 (STAT3) activator.Fórmula:C27H26BrN3O6SPureza:98%Cor e Forma:SolidPeso molecular:600.48FL3
CAS:FL3 is a novel potent eIF4F inhibitor, it induces the death of cancer cells by an original mechanism that involves the apoptosis-inducing factor and caspase 12.Fórmula:C25H23BrO5Cor e Forma:SolidPeso molecular:483.35LLL3
CAS:LLL3 is a small molecule STAT3 inhibitor.Fórmula:C16H10O4Cor e Forma:SolidPeso molecular:266.25ZYZ-488
CAS:ZYZ-488 is an Apoptosis protease activating factor-1 (Apaf-1) inhibitor, which suppresses the activation of procaspase-9 and procaspase-3.Fórmula:C20H29N3O11Pureza:99.04%Cor e Forma:SolidPeso molecular:487.46DRAK2-IN-1
CAS:Drak2-in-1: ATP-competitive DRAK2 inhibitor; IC50 = 3 nM, KI = 0.26 nM; affects DRAK1 (IC50 = 51 nM).Fórmula:C21H20N4O3Cor e Forma:SolidPeso molecular:376.41Anticancer agent 76
CAS:Compound CT2-3 is an anticancer agent that hinders growth, induces arrest, ROS, and apoptosis in NSCLC cells.Fórmula:C32H33NO5SCor e Forma:SolidPeso molecular:543.67PCAF-IN-2
CAS:PCAF-IN-2 inhibits PCAF (IC50 = 5.31 µM), induces apoptosis, and halts G2/M cell cycle, showing anti-tumor properties.Fórmula:C10H7F3N6Cor e Forma:SolidPeso molecular:268.2PARP-2-IN-3
CAS:PARP-2-IN-3 is used in the study of breast cancer as a PARP-2 inhibitor with antitumor activity that induces apoptosis (apoptosis) and necrosis in cancer cells.
Fórmula:C20H20ClN3O3Pureza:99.33%Cor e Forma:SolidPeso molecular:385.84Ki23057
CAS:Ki23057, a FGFR2 inhibitor, boosts chemo effects in resistant gastric cancer, may work with SN38/PTX/VP16, enhancing apoptosis via ERCC1/p53 synergy.Fórmula:C30H35N3O4Cor e Forma:SolidPeso molecular:501.62TNF-α-IN-18
CAS:TNF-α-IN-18 is a small molecule TNF-α inhibitor that blocks NF-κB translocation, alleviates sepsis in models, and protects against rheumatoid arthritis in mice.Fórmula:C16H7ClF2O4Pureza:99.77%Cor e Forma:SolidPeso molecular:336.67PD-1-IN-18
CAS:PD-1-IN-18 is a PD1 inhibitor of signaling pathway, and acts as an immunomodulator.Fórmula:C11H17N5O8Pureza:98%Cor e Forma:SolidPeso molecular:347.28
