Apoptose
Os inibidores da apoptose são compostos que previnem ou retardam o processo de morte celular programada, conhecido como apoptose. Esses inibidores são vitais no estudo dos mecanismos de sobrevivência celular e são usados para investigar doenças onde a apoptose é desregulada, como câncer, distúrbios neurodegenerativos e doenças autoimunes. Ao modular a apoptose, esses inibidores podem ajudar no desenvolvimento de terapias destinadas a controlar a morte celular. Na CymitQuimica, oferecemos uma ampla seleção de inibidores da apoptose de alta qualidade para apoiar sua pesquisa em biologia celular, oncologia e áreas relacionadas.
Subcategorias de "Apoptose"
- ASK(9 produtos)
- BCL(5 produtos)
- Caspase(151 produtos)
- FOXO1(2 produtos)
- IAP(67 produtos)
- Mdm2(12 produtos)
- PD-1/PD-L1(105 produtos)
- PDK(9 produtos)
- PERK(26 produtos)
- Serina/treonina quinase(18 produtos)
- Survivina(14 produtos)
- TNF(58 produtos)
- c-RET(61 produtos)
- p53(63 produtos)
Exibir 6 mais subcategorias
Foram encontrados 6043 produtos de "Apoptose"
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S1QEL1.1
CAS:S1QEL1.1 (S1QEL) is an electron leakage inhibitor that inhibits O2-induced ROS generation and prevents O2-induced DA closure.Fórmula:C23H24N4O3SPureza:99.93%Cor e Forma:SolidPeso molecular:436.53Ref: TM-T34472
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CAS:Famitinib (SHR1020), an oral drug, inhibits c-kit, VEGFR-2, and PDGFRβ (IC50: 2.3/4.7/6.6 nM) and triggers apoptosis in gastric cancer.
Fórmula:C23H27FN4O2Cor e Forma:SolidPeso molecular:410.48Vin-C01
CAS:Vin-C01, a potent protector of pancreatic β-cells (EC50=0.22μM), aids in type 2 diabetes research by preventing STZ-induced β-cell apoptosis.Fórmula:C20H24N2OCor e Forma:SolidPeso molecular:308.42Epofolate
CAS:Epofolate: folate receptor-targeted antimitotic, delivers epothilone to cancer cells, inhibits mitosis, may halt tumor growth. Check clinical trials.Fórmula:C67H92N16O22S3Cor e Forma:SolidPeso molecular:1569.74Hetrombopag
CAS:Hetrombopag: potent thrombopoietin receptor agonist, well tolerated, safe, promising for immune thrombocytopenia research.Fórmula:C25H22N4O5Cor e Forma:SolidPeso molecular:458.47SDZ 224-015
CAS:SDZ 224-015 is an inhibitor of interleukin-1β (IL-1β) converting enzyme and caspase-1 with anti-COVID-19 and anti-inflammatory activity.Fórmula:C30H35Cl2N3O9Pureza:95.49% - 95.49%Cor e Forma:SolidPeso molecular:652.52HJC-0123
CAS:HJC-0123: inhibits STAT3, boosts cleaved caspase-3, hinders cell growth, triggers apoptosis, effective in ER-negative breast/pancreatic cancer.Fórmula:C24H16N2O3SCor e Forma:SolidPeso molecular:412.46CT-1
CAS:CT-1 is a DNA minor groove ligand and causes p53-dependent breast cancer cell apoptosis.
Fórmula:C29H23F3N4OPureza:99.79%Cor e Forma:SolidPeso molecular:500.51CDK1/Cyc B-IN-1
CAS:CDK1/Cyc B-IN-1: Potent CDK1/Cyc B inhibitor, IC50 97 nM, induces apoptosis, arrests G2/M cycle, halts cancer growth.Fórmula:C14H12ClN3O2S2Cor e Forma:SolidPeso molecular:353.85Setafrastat
CAS:Setafrastat is a vascular endothelial growth factor (VEGF) promotor and rotamase inhibitor.Fórmula:C25H33F2N3O4Cor e Forma:SolidPeso molecular:477.54HJC0416
CAS:HJC0416 is a potent orally bioavailable signal transducer and activator of transcription 3 inhibitor.Fórmula:C18H17ClN2O4SPureza:98%Cor e Forma:SolidPeso molecular:392.86Necrostatin-7
CAS:Necrostatin-7 (Necrostatin 7) is a necrotic apoptosis inhibitor with cardioprotective effects that inhibits RANK-NFATc1 signaling.Fórmula:C16H10FN5OS2Pureza:98.71%Cor e Forma:SolidPeso molecular:371.41VRT-043198
CAS:VRT-043198, a VX-765 metabolite, is a potent ICE/caspase-1 inhibitor, crossing the blood-brain barrier with K i of 0.8/0.6 nM.Fórmula:C22H29ClN4O6Cor e Forma:SolidPeso molecular:480.94CMLD012072
CAS:CMLD012072 is a potent eukaryotic initiation factor 4A (eIF4A) inhibitor with potent anti-neoplastic activity. It can induce RNA clamping of eIF4A1 and eIF4A2.Fórmula:C32H32N2O7Pureza:98%Cor e Forma:SolidPeso molecular:556.61AG6033
CAS:AG6033, a novel CRBN modulator, degrades GSPT1/IKZF1 and inhibits various tumors.Fórmula:C30H23N5O4Cor e Forma:SolidPeso molecular:517.53HDAC-IN-31
CAS:HDAC-IN-31: Oral HDAC inhibitor; targets HDAC1, 2, 3; weak on HDAC8; potential in fighting lymphoma.Fórmula:C25H24N4O2Cor e Forma:SolidPeso molecular:412.48XMD15-44
CAS:XMD15-44, a RET kinase inhibitor, demonstrates potent growth-inhibitory effects on RAT1 cells transformed by RET/C634R and RET/M918T, with IC50 values of 11.5 nM and 8.3 nM, respectively. It effectively inhibits RET kinase activity and signaling in human thyroid cancer cell lines harboring oncogenic RET alleles, thereby reducing cell proliferation.Fórmula:C29H29F3N4OCor e Forma:SolidPeso molecular:506.56RIPK1-IN-15
CAS:RIPK1-IN-15 (Compound 2.5) is a potent RIPK1 inhibitor that has the potential in neurodegenerative, autoimmune, and inflammatory diseases research [1].Fórmula:C19H19N3O2Cor e Forma:SolidPeso molecular:321.37Ferroptosis-IN-4
CAS:Ferroptosis-IN-4 (compound 6k), an inhibitor of ferroptosis, exhibits an EC50 of 20 μM and lacks significant cytotoxicity. It demonstrates a protective role in glycerol-induced RM-AKI mice by alleviating kidney dysfunction [1].Fórmula:C17H24ClN3O2Peso molecular:337.84ABT-100
CAS:ABT-100 is a potent, highly selective, and orally active farnesyl transferase inhibitor with broad-spectrum antitumor activity.Fórmula:C27H19F3N4O3Pureza:98%Cor e Forma:SolidPeso molecular:504.46
