Apoptose
Os inibidores da apoptose são compostos que previnem ou retardam o processo de morte celular programada, conhecido como apoptose. Esses inibidores são vitais no estudo dos mecanismos de sobrevivência celular e são usados para investigar doenças onde a apoptose é desregulada, como câncer, distúrbios neurodegenerativos e doenças autoimunes. Ao modular a apoptose, esses inibidores podem ajudar no desenvolvimento de terapias destinadas a controlar a morte celular. Na CymitQuimica, oferecemos uma ampla seleção de inibidores da apoptose de alta qualidade para apoiar sua pesquisa em biologia celular, oncologia e áreas relacionadas.
Subcategorias de "Apoptose"
- ASK(9 produtos)
- BCL(8 produtos)
- Caspase(147 produtos)
- FOXO1(3 produtos)
- IAP(67 produtos)
- Mdm2(12 produtos)
- PD-1/PD-L1(140 produtos)
- PDK(9 produtos)
- PERK(26 produtos)
- Serina/treonina quinase(19 produtos)
- Survivina(14 produtos)
- TNF(91 produtos)
- c-RET(61 produtos)
- p53(63 produtos)
Exibir 6 mais subcategorias
Foram encontrados 6114 produtos de "Apoptose"
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Ceranib-2
CAS:Ceranib-2, a ceramidase inhibitor (IC50: 28 μM, SKOV3), reduces sphingosine/S1P and promotes apoptosis, showing anticancer properties.
Fórmula:C25H19NO3Pureza:98.49%Cor e Forma:SolidPeso molecular:381.42F5446
CAS:F5446 is a selective small molecule SUV39H1 methyltransferase inhibitor, promotes apoptosis in colorectal cancer cells by inhibiting the deposition of H3K9me3.Fórmula:C26H17ClN2O8SPureza:98.56%Cor e Forma:SolidPeso molecular:552.94PERK-IN-3
CAS:PERK-IN-3 is a potent inhibitor of PERK(IC50 of 7.4 nM).Fórmula:C22H16F2N4O2Pureza:98%Cor e Forma:SolidPeso molecular:406.38STAT3-IN-11
CAS:STAT3-IN-11 is a STAT3 inhibitor.STAT3-IN-11 promotes apoptosis in cancer cells and is a candidate compound for the treatment of cancer.Fórmula:C20H17NO4Pureza:98.3%Cor e Forma:SolidPeso molecular:335.35SMBA1
CAS:SMBA1 is a Bax agonist with antitumor activity that can induce cell cycle arrest and apoptosis in malignant glioma cells.Fórmula:C20H13NO3Pureza:99.2%Cor e Forma:SolidPeso molecular:315.32Apoptosis inducer 6
CAS:Apoptosis inducer 6 is an anticancer agent with broad-spectrum anticancer activity that induces apoptosis, which triggers cell death.Fórmula:C27H26N4O3SCor e Forma:SolidPeso molecular:486.59BP-1-108
CAS:BP-1-108 is a potent and selective STAT5 inhibitor.Fórmula:C32H38N2O6SCor e Forma:SolidPeso molecular:578.72TSI-13-57
CAS:TSI-13-57 is a MyD88 inhibitor or pan-TLR inhibitor that suppresses MyD88 TIR domain dimerization ,inhibits LPS-induced TNF-α (IC50 = 6.73 mM).Fórmula:C28H29N3O3Pureza:99.63%Cor e Forma:SolidPeso molecular:455.55Topoisomerase II inhibitor 9
CAS:Topoisomerase II inhibitor 9: Topo II blocker (IC50: 0.97 μM), DNA intercalator (IC50: 43.51 μM), arrests G2/M in Hep G-2 cells and triggers apoptosis.
Fórmula:C22H17N7O3S2Cor e Forma:SolidPeso molecular:491.55HDACs/mTOR Inhibitor 1
CAS:HDACs/mTOR Inhibitor 1 is a dual HDACs and mammalian target of Rapamycin (mTOR) target inhibitor for treating hematologic malignancies (IC50s: 0.19 nM, 1.8 nM,Fórmula:C28H38N8O5Cor e Forma:SolidPeso molecular:566.65SGC-STK17B-1
CAS:SGC-STK17B-1 is a potent and selective inhibitor of STK17B/DRAK2 kinase.Fórmula:C16H10N2O2S3Cor e Forma:SolidPeso molecular:358.46AMXT1501
CAS:AMXT1501 is a polyamine uptake inhibitor, also inhibiting the putrescine transport in epimastigotes (the insect stage of t. cruzi)Fórmula:C32H68N6O2Cor e Forma:SolidPeso molecular:568.92CCT128930
CAS:'CCT128930, potent Akt2 inhibitor (IC50=6 nM), 28x more selective over PKA.'Fórmula:C18H20ClN5Pureza:99.07% - 99.18%Cor e Forma:SolidPeso molecular:341.84Ref: TM-T6303
2mg42,00€5mg65,00€10mg94,00€25mg170,00€50mg273,00€100mg409,00€200mg652,00€1mL*10mM (DMSO)71,00€Mcl1-IN-9
CAS:Mcl1-IN-9 is a potent myeloid cell leukemia-1 (Mcl-1) Inhibitor with an IC50 of 446 nM in reengineered BCR-ABL+ B-ALL cells and a Ki of 0.03 nM.
Fórmula:C37H39ClN4O4Pureza:98%Cor e Forma:SolidPeso molecular:639.18HDAC-IN-42
CAS:HDAC-IN-42, a potent HDAC inhibitor: IC50 - 0.19μM (HDAC1), 4.98μM (HDAC6); halts cancer cell growth, triggers apoptosis & G2/M arrest.Fórmula:C20H15NO7Cor e Forma:SolidPeso molecular:381.34UA 62784
CAS:Blocks microtubule growth, spurs cell apoptosis, enhances vinblastine's effect in HeLa cells, mistakenly seen as CENP-E ATPase inhibitor.Fórmula:C23H15NO3Cor e Forma:SolidPeso molecular:353.37SD-36
CAS:SD-36: Potent, selective PROTAC STAT3 degrader, Kd ~50 nM, effective on mutants, IC50=10 nM, strong anti-tumor effects, enables mouse tumor regression.Fórmula:C59H62F2N9O12PPureza:98% - >99.99%Cor e Forma:SoildPeso molecular:1158.15TRAF-STOP inhibitor 6877002
CAS:TRAF-STOP 6877002 inhibits CD40-TRAF6, curbing leukocyte recruitment and macrophage activation/proliferation in plaques.Fórmula:C17H17NOPureza:99.76%Cor e Forma:SolidPeso molecular:251.32Melflufen
CAS:Melflufen, a dipeptide prodrug of Melphalan, is an alkylating agent with strong antitumor activity in MM, causing DNA damage and cytotoxicity.Fórmula:C24H30Cl2FN3O3Pureza:97.056%Peso molecular:498.42PHA-690509
CAS:PHA-690509 is a cyclin-dependent kinase 2 inhibitor. It potentially for the treatment of cancer.Fórmula:C17H21N3O2SPureza:98%Cor e Forma:SolidPeso molecular:331.43
