Apoptose
Os inibidores da apoptose são compostos que previnem ou retardam o processo de morte celular programada, conhecido como apoptose. Esses inibidores são vitais no estudo dos mecanismos de sobrevivência celular e são usados para investigar doenças onde a apoptose é desregulada, como câncer, distúrbios neurodegenerativos e doenças autoimunes. Ao modular a apoptose, esses inibidores podem ajudar no desenvolvimento de terapias destinadas a controlar a morte celular. Na CymitQuimica, oferecemos uma ampla seleção de inibidores da apoptose de alta qualidade para apoiar sua pesquisa em biologia celular, oncologia e áreas relacionadas.
Subcategorias de "Apoptose"
- ASK(9 produtos)
- BCL(11 produtos)
- Caspase(144 produtos)
- FOXO1(3 produtos)
- IAP(67 produtos)
- Mdm2(12 produtos)
- PD-1/PD-L1(139 produtos)
- PDK(9 produtos)
- PERK(26 produtos)
- Serina/treonina quinase(18 produtos)
- Survivina(14 produtos)
- TNF(93 produtos)
- c-RET(61 produtos)
- p53(63 produtos)
Exibir 6 mais subcategorias
Foram encontrados 6071 produtos de "Apoptose"
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Ferroptosis inducer-1
CAS:Ferroptosis inducer-1 is a Ferroptosis inducer with antitumor potential .Fórmula:C25H21ClN2O5Cor e Forma:SolidPeso molecular:464.9VEGFR-2-IN-23
CAS:VEGFR-2-IN-23 (11b) is a potent VEGFR-2 inhibitor with an IC50 of 0.34 nM, exhibits antitumor effects, and causes G1 cell cycle arrest.Fórmula:C22H15N5O2Cor e Forma:SolidPeso molecular:381.39GZD856
CAS:GZD856 is an orally bioavailable PDGFRα/β inhibitor (IC50s: 68.6 and 136.6 nM) with anti-lung cancer activities.Fórmula:C29H27F3N6OPureza:98%Cor e Forma:SolidPeso molecular:532.56PD-1/PD-L1-IN-14
CAS:PD-1/PD-L1-IN-14 (compound 17) is an inhibitor of PD-1/PD-L1 interaction (IC50=27.8 nM).Fórmula:C24H24N4O2Cor e Forma:SolidPeso molecular:400.47DPQZ
CAS:DPQZ is an anti-tubulin compound acting by inducing cell apoptosis in human oral cancer cells through Ras/Raf inhibition and MAP kinases activation.Fórmula:C20H17N3OPureza:98%Cor e Forma:SolidPeso molecular:315.37Tubulin/HDAC-IN-1
CAS:Tubulin/HDAC-IN-1 is a dual inhibitor for tubulin & HDAC8, blocking polymerization & targeting HDAC8 (IC50: 150 nM), and induces cancer cell apoptosis.Fórmula:C21H18N4O3Cor e Forma:SolidPeso molecular:374.39EGFR-IN-46
CAS:EGFR-IN-46: Potent EGFR/FAK inhibitor (IC50: 20.17 & 14.25 nM), curbs cancer cell growth, triggers apoptosis.Fórmula:C27H32F3N3O3Cor e Forma:SolidPeso molecular:503.56SB-218078
CAS:SB-218078 is less potently inhibits Cdc2 (IC50: 250 nM) and PKC (IC50: 1000 nM).Fórmula:C24H15N3O3Pureza:98%Cor e Forma:SolidPeso molecular:393.39SKLB70326
CAS:SKLB70326 is a cell-cycle progression inhibitor that acts by inducing G0/G1 phase arrest and apoptosis in human hepatic carcinoma cells.Fórmula:C15H13N3O2SPureza:98%Cor e Forma:SolidPeso molecular:299.35CDK6/PIM1-IN-1
CAS:CDK6/PIM1-IN-1: A dual inhibitor for CDK6 (39 nM IC50) & PIM1 (88 nM), also targets CDK4 (3.6 nM IC50), halts AML cell growth, and induces apoptosis.Fórmula:C25H28FN9Cor e Forma:SolidPeso molecular:473.55EGFR-IN-88
CAS:EGFR-IN-88 (Compound 4i), an EGFR inhibitor with an IC50 of 87 nM, exhibits cytotoxic effects on A549 cells at an IC50 of 3.902 μM and can induce cell apoptosisFórmula:C22H18Cl2N4O2SPureza:98%Cor e Forma:SolidPeso molecular:473.37WK-298
CAS:WK-298 is an effective MDM2/MDMX-p53 interaction inhibitor.Fórmula:C35H38Cl2N6OPureza:98%Cor e Forma:SolidPeso molecular:629.62Bcl-2/Mcl-1-IN-1
CAS:Bcl-2/Mcl-1-IN-1 is an inhibitor of Bcl-2 (Ki: 4.53 μM) and Mcl-1 (Ki: 1.19 μM).Bcl-2/Mcl-1-IN-1 can be used in cancer research.Fórmula:C28H23NO3Cor e Forma:SolidPeso molecular:421.49ZYZ-488
CAS:ZYZ-488 is an Apoptosis protease activating factor-1 (Apaf-1) inhibitor, which suppresses the activation of procaspase-9 and procaspase-3.Fórmula:C20H29N3O11Pureza:99.04%Cor e Forma:SolidPeso molecular:487.46EGFR/HER2/TS-IN-1
CAS:EGFR/HER2/TS-IN-1 inhibits EGFR (0.203 μM), HER2 (0.088 μM), TS (0.168 μM), and induces apoptosis in MCF7 cells.Fórmula:C24H15N5O4S2Cor e Forma:SolidPeso molecular:501.54AMPK activator 11
CAS:AMPK Activator 11 is a nanomolar potent inhibitor of cell proliferation in various colorectal carcinomas (CRCs), acting through the selective activation of AMP-Fórmula:C25H20N4O2Pureza:98%Cor e Forma:SolidPeso molecular:408.45MDM2-p53-IN-16
CAS:MDM2-p53-IN-16 inhibits p53/MDM2 complex (IC 50 = 4.3 nM), triggers p53, causes GBM cell apoptosis, useful in cancer research.Fórmula:C32H33N3O5Cor e Forma:SolidPeso molecular:539.62YLT205
CAS:YLT205 is an inducer of apoptosis in human colorectal cells that acts by inhibiting tumor growth.Fórmula:C16H12BrClN4O2S2Pureza:98%Cor e Forma:SolidPeso molecular:471.78MR2938
CAS:MR2938: AChE inhibitor (IC50=5.04μM), reduces NO (IC50=3.29μM), blocks MAPK/JNK, NF-κB; for AD research.Fórmula:C21H24N4O3Cor e Forma:SolidPeso molecular:380.44Talaporfin free acid
CAS:Talaporfin, an effective tumor localizer, can produce the selective degradation of tumor tissue following light exposure.Fórmula:C38H41N5O9Cor e Forma:SolidPeso molecular:711.76
