Apoptose
Os inibidores da apoptose são compostos que previnem ou retardam o processo de morte celular programada, conhecido como apoptose. Esses inibidores são vitais no estudo dos mecanismos de sobrevivência celular e são usados para investigar doenças onde a apoptose é desregulada, como câncer, distúrbios neurodegenerativos e doenças autoimunes. Ao modular a apoptose, esses inibidores podem ajudar no desenvolvimento de terapias destinadas a controlar a morte celular. Na CymitQuimica, oferecemos uma ampla seleção de inibidores da apoptose de alta qualidade para apoiar sua pesquisa em biologia celular, oncologia e áreas relacionadas.
Subcategorias de "Apoptose"
- ASK(9 produtos)
- BCL(11 produtos)
- Caspase(144 produtos)
- FOXO1(3 produtos)
- IAP(67 produtos)
- Mdm2(12 produtos)
- PD-1/PD-L1(139 produtos)
- PDK(9 produtos)
- PERK(26 produtos)
- Serina/treonina quinase(18 produtos)
- Survivina(14 produtos)
- TNF(93 produtos)
- c-RET(62 produtos)
- p53(63 produtos)
Exibir 6 mais subcategorias
Foram encontrados 6064 produtos de "Apoptose"
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CDK9-IN-7
CAS:CDK9-IN-7: selective, oral CDK9/cyclin T inhibitor with 11 nM IC50, stronger than CDK4/6.Fórmula:C29H37N7O2SPureza:98.08%Cor e Forma:SolidPeso molecular:547.71Ref: TM-T10745
1mg90,00€5mg208,00€10mg304,00€25mg457,00€50mg630,00€100mg845,00€200mg1.121,00€1mL*10mM (DMSO)229,00€Exisulind
CAS:Exisulind (CP248) triggers apoptosis via PKG activation, shows antitumor effects, and inhibits growth in various rodent cancer models.Fórmula:C20H17FO4SPureza:97.94%Cor e Forma:SolidPeso molecular:372.41JY-2
CAS:JY-2 is a forkhead transcription factor O1 (FoxO1) inhibitor with antidiabetic activity that inhibits FoxO1 transcription and can be used to study psoriasis.Fórmula:C13H7Cl2N3OPureza:99.66%Cor e Forma:SolidPeso molecular:292.12HBDDE
CAS:HBDDE inhibits PKCα/γ (IC50: 43/50 μM), favors them over PKCδ/βI/βII, and induces neuronal apoptosis. Derived from ellagic acid.Fórmula:C16H18O8Pureza:99.99%Cor e Forma:SolidPeso molecular:338.31Droloxifene
CAS:Droloxifene, a tamoxifen derivative and oral SERM, induces p53 and apoptosis; Fluroxifene protects bone, blocks estrogen and implantation.Fórmula:C26H29NO2Pureza:99.86% - 99.97%Cor e Forma:Solid PowderPeso molecular:387.51Ref: TM-T11098
1mg54,00€5mg116,00€10mg170,00€25mg283,00€50mg419,00€100mg562,00€500mgA consultar1mL*10mM (DMSO)133,00€GSK-3β inhibitor 3
CAS:GSK-3β inhibitor 3 is a covalent inhibitor (IC50: 6.6 μM) of glycogen synthase kinase 3β (GSK-3β) that is potent, selective, and irreversible.GSK-3β inhibitor 3Fórmula:C18H14FNO2SPureza:97.53%Cor e Forma:SolidPeso molecular:327.37Ref: TM-T35554
1mg92,00€5mg188,00€10mg283,00€25mg530,00€50mg795,00€100mg1.169,00€1mL*10mM (DMSO)215,00€HS-276
CAS:HS-276, a selective oral TAK1 inhibitor (Ki: 2.5 nM), also targets CLK2, GCK, ULK2, MAP4K5; potential for RA research.Fórmula:C24H29N5O2Pureza:97.67% - 98.81%Cor e Forma:SolidPeso molecular:419.52Ref: TM-T62209
1mg66,00€5mg144,00€10mg219,00€25mg430,00€50mg690,00€100mg1.064,00€200mg1.434,00€1mL*10mM (DMSO)170,00€UC-112
CAS:UC-112 is a novel potent IAP inhibitor and potently inhibits cell growth in two human melanoma and two human prostate cancer cell lines (IC50=0.7-3.4 uM).Fórmula:C22H24N2O2Pureza:99.54%Cor e Forma:SolidPeso molecular:348.44Ref: TM-T17195
1mg35,00€2mg47,00€5mg73,00€10mg104,00€25mg213,00€50mg329,00€100mg470,00€500mgA consultar1mL*10mM (DMSO)82,00€T025
CAS:T025 inhibits CLK1-4 (Kds: 0.074-6.5 nM), shows anti-cancer effects (IC50: 30-300 nM), useful for MYC-related disease research.Fórmula:C21H18N8Pureza:98.08%Cor e Forma:SolidPeso molecular:382.42Ref: TM-T13058
1mg143,00€5mg354,00€10mg528,00€25mg852,00€50mg1.159,00€100mg1.568,00€500mg3.125,00€1mL*10mM (DMSO)378,00€NecroX-7
CAS:NecroX-7 (LC-280126) is a potent free radical scavenger and a HMGB1 (high-mobility group box 1) inhibitor.Fórmula:C24H29N3O3SPureza:98.22%Cor e Forma:SolidPeso molecular:439.57Mitazalimab
CAS:Mitazalimab (ADC-1013/JNJ-64457107) is a CD40 agonist that stimulates T cells to attack tumors and remodels the tumor microenvironment.Pureza:95.1% (SDS-PAGE); 98.7% (SEC-HPLC) - 95.1% (SDS-PAGE); 98.7% (SEC-HPLC)Cor e Forma:LiquidSarmustine
CAS:<p>SarCNU is an alkylating anticancer drug targeting prostate cancer through p53 pathways and selects P140K MGMT-transduced CD34(+) cells.</p>Fórmula:C6H11ClN4O3Pureza:98.29% - 99.71%Cor e Forma:SolidPeso molecular:222.63Bomedemstat ditosylate
CAS:<p>Bomedemstat (IMG-7289) is an LSD1 inhibitor for acute myeloid leukemia, MDS, and Myelofibrosis; induces apoptosis by regulating p53, PUMA, and BCLXL.</p>Fórmula:C42H50FN7O8S2Pureza:99.05%Cor e Forma:SolidPeso molecular:864.02Trk-IN-9
CAS:Trk-IN-9 is a TRK inhibitor with anticancer and antiproliferative activity and can be used in cancer research.Fórmula:C23H24ClFN6OPureza:98.15%Cor e Forma:SolidPeso molecular:454.93RS1-PDK1 inhibitor
CAS:<p>RS1-PDK1 inhibitor (RS 1) is a selective inhibitor of the protein kinase PDK1 that can be used to treat and prevent disease or disorders.</p>Fórmula:C15H9ClN2O2S3Pureza:98.12%Cor e Forma:SolidPeso molecular:380.89Tanimilast
CAS:Tanimilast (CHF-6001) is a potent PDE4 inhibitor with IC50 of 0.026 nM, used topically for obstructive lung disease.Fórmula:C30H30Cl2F2N2O8SPureza:99.18%Cor e Forma:SolidPeso molecular:687.54R306465
CAS:R306465 (JNJ-16241199) is an HDAC 1 inhibitor with broad-spectrum anti-tumor activity, inducing apoptosis, and can be used to study solid tumors.Fórmula:C19H19N5O4SPureza:98.46% - 99.54%Cor e Forma:SolidPeso molecular:413.45Dasatinib hydrochloride
CAS:Dasatinib hydrochloride is an oral Src/Bcr-Abl inhibitor with potent antitumor effects, Ki values of 16 pM (Src) and 30 pM (Bcr-Abl).Fórmula:C22H27Cl2N7O2SPureza:99.88% - 99.98%Cor e Forma:SolidPeso molecular:524.47Triparanol
CAS:Triparanol (NSC-65345) interferes with posttranslational modification of Hedgehog signaling molecules as well as the sterol sensing domain of its receptor PTCH1Fórmula:C27H32ClNO2Pureza:99.72%Cor e Forma:SolidPeso molecular:438Ref: TM-T26296
1mg284,00€5mg645,00€10mg867,00€25mg1.283,00€50mg1.700,00€100mg2.347,00€1mL*10mM (DMSO)690,00€TT01001
CAS:TT01001, a mitoNEET agonist, may treat type II diabetes by reducing oxidative stress and preventing neuronal death.Fórmula:C15H19Cl2N3O2SPureza:99.93%Cor e Forma:SolidPeso molecular:376.3
