Apoptose
Os inibidores da apoptose são compostos que previnem ou retardam o processo de morte celular programada, conhecido como apoptose. Esses inibidores são vitais no estudo dos mecanismos de sobrevivência celular e são usados para investigar doenças onde a apoptose é desregulada, como câncer, distúrbios neurodegenerativos e doenças autoimunes. Ao modular a apoptose, esses inibidores podem ajudar no desenvolvimento de terapias destinadas a controlar a morte celular. Na CymitQuimica, oferecemos uma ampla seleção de inibidores da apoptose de alta qualidade para apoiar sua pesquisa em biologia celular, oncologia e áreas relacionadas.
Subcategorias de "Apoptose"
- ASK(9 produtos)
- BCL(11 produtos)
- Caspase(144 produtos)
- FOXO1(3 produtos)
- IAP(67 produtos)
- Mdm2(12 produtos)
- PD-1/PD-L1(139 produtos)
- PDK(9 produtos)
- PERK(26 produtos)
- Serina/treonina quinase(18 produtos)
- Survivina(14 produtos)
- TNF(93 produtos)
- c-RET(61 produtos)
- p53(63 produtos)
Exibir 6 mais subcategorias
Foram encontrados 6071 produtos de "Apoptose"
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p53-MDM2-IN-1
CAS:<p>p53-MDM2-IN-1 (Example 30), an inhibitor targeting the p53-MDM2/X protein interaction, exhibits a K i value of 23.35 µM.</p>Fórmula:C23H20ClN3O3Pureza:99.98%Cor e Forma:SoildPeso molecular:421.88LCS3
CAS:LCS3 is a reversible and non-competitive synergistic inhibitor of glutathione disulfide reductase (GSR) and thioredoxin reductase 1 (TXNRD1) with IC50s of 3.3Fórmula:C11H7ClN2O4Pureza:99.84%Cor e Forma:SolidPeso molecular:266.64Erastin2
CAS:<p>Erastin2 is an iron death inducer that induces cell death by binding to the lipophilic free radical trapping antioxidant ferrostatin-1 or the iron chelator DFO.</p>Fórmula:C36H35ClN4O4Pureza:99.63%Cor e Forma:SolidPeso molecular:623.14FA16
FA16 is a selective, metabolically stable ferroptosis inducer with an IC50 value of 1.26 μM.FA16 is a derivative of 2-(trifluoromethyl)benzimidazole.FA16Fórmula:C22H27F3N4O2SPureza:99.44%Cor e Forma:SolidPeso molecular:468.54VAS 3947
CAS:VAS 3947: NOX inhibitor, induces platelet apoptosis via UPR, not linked to NOX inhibition.Fórmula:C14H10N6OSPureza:99.25%Cor e Forma:SolidPeso molecular:310.33Ref: TM-T29097
1mg48,00€5mg97,00€10mg170,00€25mg295,00€50mg424,00€100mg562,00€200mg743,00€1mL*10mM (DMSO)105,00€ZDLD20
CAS:ZDLD20 is a CDK4 inhibitor with anti-HCT116 and anticancer activity that inhibits colony formation and blocks the G1 phase of the cell cycle.Fórmula:C22H22N6OPureza:98.59%Cor e Forma:SolidPeso molecular:386.45Cot inhibitor-1
CAS:Cot inhibitor-1 selectively blocks Tpl2 kinase, reducing TNF-alpha in blood (IC50: 5.7 nM). It may treat arthritis, IBD, and certain cancers.Fórmula:C27H27Cl2FN8Pureza:98.87%Cor e Forma:SolidPeso molecular:553.46Ref: TM-T10865
1mg77,00€5mg160,00€10mg235,00€25mg424,00€50mg635,00€100mg935,00€200mg1.283,00€1mL*10mM (DMSO)187,00€Antifolate C2
CAS:Antifolate C2 (AGF 154) inhibits tumor growth with 0.14 nM IC, useful in cancer/autoimmune research.Fórmula:C19H21N5O6SPureza:99.57%Cor e Forma:SolidPeso molecular:447.46UNC0321
CAS:UNC0321 is an effective inhibitor of histone methyltransferase G9a with a Ki of 63 pM and with IC50s 9 nM and 6 nM in ECSD and CLOT assays.Fórmula:C27H45N7O3Pureza:99.80%Cor e Forma:SolidPeso molecular:515.69RET-IN-23
CAS:RET-IN-23 is an orally available and highly potent RET inhibitor with significant antitumor activity for the study of non-small cell lung cancer.Fórmula:C28H28FN11Pureza:97.46%Cor e Forma:SolidPeso molecular:537.59UCB-5307
CAS:UCB-5307 inhibits TNFR1, binds TNFα with 9 nM KD, shows slow kinetics (KD=6 nM), and penetrates hTNF/hTNFR1 complexes.Fórmula:C22H21N3OPureza:98.76%Cor e Forma:SolidPeso molecular:343.42AQ4
CAS:AQ4 is a topoisomerase II inhibitor and DNA-inserting agent that inhibits proliferation and induces apoptosis in two cell lines.Fórmula:C22H28N4O4Pureza:96.28% - 97.15%Cor e Forma:SolidPeso molecular:412.48P505-15 Acetate
CAS:<p>P505-15 Acetate inhibits spleen tyrosine kinase, reduces immune response and inflammation, and lowers arthritis severity.</p>Fórmula:C21H27N9O3Pureza:99.99%Cor e Forma:SolidPeso molecular:453.5Tiomolibdate diammonium
CAS:Tiomolibdate diammonium (NSC-286644) blocks SOD1 and COX, acting as an antiangiogenic and antitumor agent.Fórmula:H8MoN2S4Pureza:98%Cor e Forma:Brown To Black Iridescent Crystalline PowderPeso molecular:260.28HTH-01-091
CAS:HTH-01-091 is a potent and selective maternal embryonic leucine zipper kinase (MELK) inhibitor (IC50: 10.5 nM).HTH-01-091 inhibits PIM1/2/3, RIPK2, DYRK3,Fórmula:C26H28Cl2N4O2Pureza:98.82%Cor e Forma:SolidPeso molecular:499.43Ref: TM-T24152
1mg281,00€5mg692,00€10mg938,00€25mg1.454,00€50mg1.882,00€100mg2.375,00€1mL*10mM (DMSO)775,00€HBED
CAS:HBED (CHELII) is an iron chelator and can be used in research on the treatment of chronic iron overload and acute iron poisoning.Fórmula:C20H24N2O6Pureza:97.35% - 98.58%Cor e Forma:SolidPeso molecular:388.41STAT3-IN-13
CAS:STAT3-IN-13 is a STAT3 inhibitor with antiproliferative activity that induces apoptosis and can be used to study breast and liver cancer.Fórmula:C21H20N6O3SPureza:98.89%Cor e Forma:SolidPeso molecular:436.49NLRP3/AIM2-IN-3
CAS:NLRP3/AIM2-IN-3 selectively blocks NLRP3/AIM2 inflammasomes; IC50 for cell lysis is 0.077 μM, disrupting ASC oligomerization.Fórmula:C16H14N2O2Pureza:97.04%Cor e Forma:SolidPeso molecular:266.29Ref: TM-T60442
5mg74,00€10mg107,00€25mg216,00€50mg354,00€100mg567,00€500mg1.198,00€1mL*10mM (DMSO)82,00€CBS9106
CAS:CBS9106 (SL-801) is a CRM1 inhibitor with CRM1-degrading and anti-tumor activity that inhibits CRM1-dependent nuclear export.Fórmula:C18H21ClF3N3O3Pureza:98.98%Cor e Forma:SolidPeso molecular:419.83HS-276
CAS:HS-276, a selective oral TAK1 inhibitor (Ki: 2.5 nM), also targets CLK2, GCK, ULK2, MAP4K5; potential for RA research.Fórmula:C24H29N5O2Pureza:97.67% - 98.81%Cor e Forma:SolidPeso molecular:419.52Ref: TM-T62209
1mg66,00€5mg144,00€10mg219,00€25mg430,00€50mg690,00€100mg1.064,00€200mg1.434,00€1mL*10mM (DMSO)170,00€
