Apoptose
Os inibidores da apoptose são compostos que previnem ou retardam o processo de morte celular programada, conhecido como apoptose. Esses inibidores são vitais no estudo dos mecanismos de sobrevivência celular e são usados para investigar doenças onde a apoptose é desregulada, como câncer, distúrbios neurodegenerativos e doenças autoimunes. Ao modular a apoptose, esses inibidores podem ajudar no desenvolvimento de terapias destinadas a controlar a morte celular. Na CymitQuimica, oferecemos uma ampla seleção de inibidores da apoptose de alta qualidade para apoiar sua pesquisa em biologia celular, oncologia e áreas relacionadas.
Subcategorias de "Apoptose"
- ASK(9 produtos)
- BCL(6 produtos)
- Caspase(151 produtos)
- FOXO1(2 produtos)
- IAP(67 produtos)
- Mdm2(12 produtos)
- PD-1/PD-L1(106 produtos)
- PDK(9 produtos)
- PERK(26 produtos)
- Serina/treonina quinase(18 produtos)
- Survivina(14 produtos)
- TNF(59 produtos)
- c-RET(61 produtos)
- p53(63 produtos)
Exibir 6 mais subcategorias
Foram encontrados 6041 produtos de "Apoptose"
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HJC0152 free base
CAS:HJC0152 (free base) is an orally active, potent STAT3 inhibitor that impedes cell cycle progression, induces apoptosis, and notably reduces MDA-MB-231 xenograftFórmula:C15H13Cl2N3O4Pureza:98%Cor e Forma:SolidPeso molecular:370.19MAO-B-IN-26
CAS:MAO-B-IN-26 (Compound IC9) serves as both a MAO-B and acetylcholinesterase inhibitor.Fórmula:C17H12BrNOPureza:98%Cor e Forma:SolidPeso molecular:326.19GDC-2394
CAS:GDC-2394: Oral, selective NLRP3 inhibitor; blocks IL-1β (human 0.4μM, mouse 0.1μM), spares NLRC4.Fórmula:C20H25N5O4SCor e Forma:SolidPeso molecular:431.51TM5441 sodium
CAS:TM5441, an orally bioavailable plasminogen activator inhibitor-1 (PAI-1) inhibitor with IC50 values ranging from 13.9 to 51.1 μM, effectively induces intrinsic apoptosis across multiple human cancer cell lines. Additionally, it mitigates Nω-nitro-l-arginine methyl ester-induced cardiac hypertension and vascular senescence [1] [2].Fórmula:C21H16ClN2NaO6Cor e Forma:SolidPeso molecular:450.8eIF4A3-IN-9
CAS:eIF4A3-IN-9, a silvestrol analogue, disrupts eIF4F complex assembly; EC50s: 29/450/80 nM (myc/tub-LUC, MB-231 cells); for cancer research.Fórmula:C28H27NO8Cor e Forma:SolidPeso molecular:505.52MTP
CAS:MTP, a PKM2 inhibitor, promotes apoptosis in cancer cells via caspase-3 activation while also inducing autophagy and enhancing ROS generation.Fórmula:C29H23F3N4O2Pureza:98%Cor e Forma:SolidPeso molecular:516.51Anticancer agent 118
CAS:Anticancer Agent 118, an N‑acylated ciprofloxacin derivative, exhibits antibacterial efficacy against Gram-positive strains and antiproliferative effects onFórmula:C19H19ClFN3O4Cor e Forma:SolidPeso molecular:407.82Riboxin
CAS:Riboxin (IDP), an orally administered purine derivative known as hypoxanthine riboside, exhibits antihypoxic and antihyperthermic effects.Fórmula:C10H14N4O11P2Cor e Forma:SolidPeso molecular:428.19HDAC-IN-59
CAS:HDAC-IN-59 (compound 13a), a potent histone deacetylase (HDAC) inhibitor, enhances intracellular reactive oxygen species (ROS) production, induces DNA damage,Fórmula:C20H25NO7Pureza:98%Cor e Forma:SolidPeso molecular:391.42iMAC2 hydrochloride
CAS:iMAC2 hydrochloride, a potent inhibitor of the mitochondrial apoptosis-induced channel (MAC), demonstrates an IC50 of 28 nM and an LD50 of 15000 nM. It exhibits an anti-apoptotic effect by blocking the release of cytochrome c [1].Fórmula:C19H22Br2Cl2FN3Cor e Forma:SolidPeso molecular:542.11AR420626
CAS:AR420626: selective FA3R agonist, guards against SALS, effects blocked by BHB, a FA3R antagonist.Fórmula:C21H18Cl2N2O3Pureza:98.62%Cor e Forma:SolidPeso molecular:417.29RIPK3-IN-4
CAS:RIPK3-IN-4 (Compound 42) is a RIPK3 inhibitor that mitigates necroptosis, inflammatory responses, and HK-2 cell damage.Fórmula:C24H18BrFN4O3SPureza:98%Cor e Forma:SolidPeso molecular:541.39eIF4A3-IN-18
CAS:eIF4A3-IN-18, a silvestrol analogue with EC50s: 0.8/35/2 nM, inhibits eIF4F complex and is cytotoxic (LC50: 0.06 nM) for cancer research.Fórmula:C29H28N2O6Cor e Forma:SolidPeso molecular:500.54BPR1J-340
CAS:BPR1J-340, a novel potent FLT3 inhibitor, shows anticancer promise, with IC50 ~25 nM and GC50 ~5 nM, causing apoptosis in AML cells.Fórmula:C29H34N8O3Cor e Forma:SolidPeso molecular:542.63Purinostat mesylate
CAS:Purinostat mesylate, a selective HDAC inhibitor (IC50: 0.81-11.5 nM), induces apoptosis and has potent anti-leukemic effects.Fórmula:C24H30N10O6SCor e Forma:SolidPeso molecular:586.63cis-3,4',5-Trimethoxy-3'-hydroxystilbene
CAS:Cis-3,4',5-Trimethoxy-3'-hydroxystilbene, a stilbene derivative, induces apoptosis through the mitochondrial release of cytochrome c and suppresses tubulin polymerization. It is also noted for its application in leukemic research [1].Fórmula:C17H18O4Cor e Forma:SolidPeso molecular:286.327Ac-YVAD-pNA
CAS:Ac-YVAD-pNA, a specific substrate for Caspase-1, serves to detect Caspase-1 activity, a crucial mediator of inflammatory processes [1] [2].Fórmula:C29H36N6O10Cor e Forma:SolidPeso molecular:628.639RIP2 kinase inhibitor 1
CAS:Potent RIP2 kinase inhibitor with 0.03 μM IC50, selective for autoimmune disease treatment.Fórmula:C17H17N5O2SPureza:98%Cor e Forma:SolidPeso molecular:355.41WNY1613
CAS:WNY1613: Potent PI3Kδ inhibitor with anti-NHL properties, induces apoptosis in cells, affects phosphorylation in vitro/in vivo.Fórmula:C29H35N9O3Cor e Forma:SolidPeso molecular:557.65Sirt1/2-IN-3
CAS:Sirt1/2-IN-3 (compound PS9) serves as a dual inhibitor of SIRT1/2, exhibiting IC50 values of 1.4 μM (SIRT1) and 2.0 μM (SIRT2), respectively.Fórmula:C17H14ClNO4SPureza:98%Cor e Forma:SolidPeso molecular:363.82
