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Ciclo celular/Ponto de verificação

Ciclo celular/Ponto de verificação

Os inibidores do ciclo celular/ponto de verificação são compostos que interrompem a progressão normal do ciclo celular, particularmente em pontos de verificação regulatórios chave. Esses inibidores são cruciais para estudar a divisão celular, entender a proliferação de células cancerígenas e desenvolver terapias anticâncer. Ao direcionar fases específicas do ciclo celular, esses inibidores podem induzir a parada do ciclo celular, levando à apoptose ou senescência em células de divisão rápida. Na CymitQuimica, oferecemos uma ampla gama de inibidores de alta qualidade do ciclo celular/ponto de verificação para apoiar sua pesquisa em biologia do câncer, biologia celular e desenvolvimento de medicamentos.

Subcategorias de "Ciclo celular/Ponto de verificação"

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Foram encontrados 3764 produtos de "Ciclo celular/Ponto de verificação"

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  • Ceftriaxone
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    Ceftriaxone

    CAS:
    Ceftriaxone: cephalosporin antibiotic, effective against Gram-positive/negative bacteria, with anti-inflammatory/antioxidant properties.
    Fórmula:C18H18N8O7S3
    Pureza:96.08%
    Cor e Forma:Solid
    Peso molecular:554.58

    Ref: TM-T75295

  • Logotipo do CymitQuimica
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    Chrexanthomycin C

    <p>Chrexanthomycin C, orally active, binds DNA (G4C2)4 G4, Kd 2.8 mM, potential in ALS research.</p>
    Fórmula:C31H24O15
    Cor e Forma:Solid
    Peso molecular:636.51

    Ref: TM-T75527

  • Cytarabine triphosphate
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    Cytarabine triphosphate

    CAS:
    Ara-CTP, active Cytarabine metabolite, inhibits DNA synthesis, predicts leukemic chemosensitivity.
    Fórmula:C9H16N3O14P3
    Cor e Forma:Solid
    Peso molecular:483.16

    Ref: TM-T38718

  • Logotipo do CymitQuimica
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    Methylcarbamyl PAF C-8

    Methylcarbamyl PAF C-8 is resistant to degradation by PAF-AH and has a half-life of over 100 minutes in platelet-poor plasma, exhibiting platelet aggregation activity. In NRK-49 cells overexpressing PAF receptor, it induces the expression of c-myc, c-fos, and activates mitogen-activated protein kinase (MAPK). Furthermore, Methylcarbamyl PAF C-8 can induce G1 phase cell cycle arrest. This compound shows potential for research in cardiovascular and anti-cancer applications.
    Cor e Forma:Odour Solid

    Ref: TM-T206879

  • Carbazole
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    Carbazole

    CAS:
    <p>Carbazole belongs to the class of carbazole-based organic compounds. Carbazole can form novel DNA small groove complexes, inhibiting the synthesis of new DNA or RNA.</p>
    Fórmula:C12H9N
    Pureza:99.82%
    Cor e Forma:Solid
    Peso molecular:167.211

    Ref: TM-PDK0380

  • Phen-DC3 Trifluoromethanesulfonate
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    Phen-DC3 Trifluoromethanesulfonate

    CAS:
    Phen-DC3 Trifluoromethanesulfonate targets G-quadruplexes and inhibits FANCJ/DinG helicases; IC50s: 65±6/50±10 nM.
    Fórmula:C36H26F6N6O8S2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:848.75

    Ref: TM-T13817L

  • GS-443902 trisodium
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    GS-443902 trisodium

    CAS:
    GS-443902 trisodium, a strong RdRp blocker, inhibits RSV/HCV with IC50 of 1.1/5 μM and is Remdesivir's active form.
    Fórmula:C12H16N5O13P3·xNa
    Cor e Forma:Solid

    Ref: TM-T38761

  • Logotipo do CymitQuimica
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    5-Aza-xylo-cytidine

    <p>5-Aza-xylo-cytidine, a purine analog with antitumor effects, inhibits DNA synthesis and induces apoptosis in lymphoid cancers.</p>
    Fórmula:C8H12N4O5
    Cor e Forma:Solid
    Peso molecular:244.2

    Ref: TM-T75220

  • Logotipo do CymitQuimica
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    Mps1-IN-6

    Mps1-IN-6 is a potent Mps1 inhibitor that demonstrates antiproliferative and antitumor activities, exhibiting an IC50 of 2.596 nM [1].
    Fórmula:C35H39N9O3
    Cor e Forma:Solid
    Peso molecular:633.74

    Ref: TM-T78965

  • 5'-O-TBDMS-dA
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    5'-O-TBDMS-dA

    CAS:
    <p>5’-O-TBDMS-dA is a modified nucleoside and can be used to synthesize DNA or RNA.</p>
    Fórmula:C16H27N5O3Si
    Cor e Forma:Solid
    Peso molecular:365.509

    Ref: TM-T37143

  • 11H-Benzo[a]carbazole
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    11H-Benzo[a]carbazole

    CAS:
    11H-Benzo[a]carbazole is a kinesin-like protein KIF11 inhibitor that can inhibit the viability of HeLa cells.
    Fórmula:C16H11N
    Pureza:99.14%
    Cor e Forma:Solid
    Peso molecular:217.27

    Ref: TM-TN9686

  • Logotipo do CymitQuimica
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    N6-Methyl-2'-O-(2-methoxyethyl) adenosine

    N6-Methyl-2’-O-(2-methoxyethyl) adenosine, a purine nucleoside analog, exhibits broad antitumor activity, particularly against indolent lymphoid malignancies.
    Fórmula:C14H21N5O5
    Cor e Forma:Solid
    Peso molecular:339.35

    Ref: TM-T75062

  • Logotipo do CymitQuimica
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    RNA polymerase II-IN-2

    RNA Pol II-IN-2 (20iii) strongly inhibits Pol II (Ki=9.5 nM), is more toxic to CHO/HEK293 than α-amanitin.
    Fórmula:C41H58N10O12S
    Cor e Forma:Solid
    Peso molecular:915.02

    Ref: TM-T74631

  • Logotipo do CymitQuimica
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    KIF2C-IN-1

    <p>KIF2C-IN-1 (Compound 7S9) is a selective and potent small molecule inhibitor of KIF2C. It stabilizes the interaction between KIF2C and microtubule proteins, preventing the depolymerization of polyglutamylated microtubules. KIF2C-IN-1 enhances the cytotoxicity of Paclitaxel in Paclitaxel-resistant triple-negative breast cancer (TNBC) cells and, when combined with Paclitaxel, significantly reduces tumor growth in mouse models.</p>
    Fórmula:C36H39ClN4O9S
    Cor e Forma:Solid
    Peso molecular:738.21263

    Ref: TM-T207280

  • Logotipo do CymitQuimica
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    Anti-EMMPRIN/CD147 Antibody

    Anti-EMMPRIN/CD147 Antibody is a human-derived antibody expressed in CHO cells, targeting Basigin. For an isotype control, refer to HumanIgG1kappa, Isotype Control.
    Cor e Forma:Odour Liquid

    Ref: TM-T9901A-803

  • Logotipo do CymitQuimica
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    DHFR-IN-8

    DHFR-IN-8 (compound 6r), a dihydrofolate reductase (DHFR) inhibitor, disrupts purine and thymidylate biosynthesis critical for cell proliferation and growth.
    Fórmula:C18H14N6S
    Cor e Forma:Solid
    Peso molecular:346.41

    Ref: TM-T79734

  • Xanthosine-5'-Triphosphate
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    Xanthosine-5'-Triphosphate

    CAS:
    <p>Xanthosine-5'-Triphosphate (5'-XTP), a nucleotide derived from the deamination of purine bases, plays a crucial role in various biological processes.</p>
    Fórmula:C10H15N4O15P3
    Cor e Forma:Solid
    Peso molecular:524.164

    Ref: TM-T40714

  • 5-Methylcytidine 5′-triphosphate
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    5-Methylcytidine 5′-triphosphate

    CAS:
    5-Methylcytidine 5′-triphosphate (5-Methyl-CTP), a modified nucleoside triphosphate, enhances translational properties and stability while reducing innate
    Fórmula:C10H18N3O14P3
    Cor e Forma:Solid
    Peso molecular:497.18

    Ref: TM-T74584

  • Logotipo do CymitQuimica
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    PAT-LM1

    PAT-LM1 is a human monoclonal antibody that targets NRB54/NONO. It is applicable in the study of hematological malignancies.
    Cor e Forma:Odour Liquid

    Ref: TM-T9901A-1103

  • Lorutengitide
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    Lorutengitide

    CAS:
    <p>Lorutengitide is a transcription-regulating peptide with antiproliferative activity.</p>
    Fórmula:C30H50N8O12
    Cor e Forma:Solid
    Peso molecular:714.764

    Ref: TM-TP3135