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Ciclo celular/Ponto de verificação

Ciclo celular/Ponto de verificação

Os inibidores do ciclo celular/ponto de verificação são compostos que interrompem a progressão normal do ciclo celular, particularmente em pontos de verificação regulatórios chave. Esses inibidores são cruciais para estudar a divisão celular, entender a proliferação de células cancerígenas e desenvolver terapias anticâncer. Ao direcionar fases específicas do ciclo celular, esses inibidores podem induzir a parada do ciclo celular, levando à apoptose ou senescência em células de divisão rápida. Na CymitQuimica, oferecemos uma ampla gama de inibidores de alta qualidade do ciclo celular/ponto de verificação para apoiar sua pesquisa em biologia do câncer, biologia celular e desenvolvimento de medicamentos.

Subcategorias de "Ciclo celular/Ponto de verificação"

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Foram encontrados 3764 produtos de "Ciclo celular/Ponto de verificação"

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  • 5-Methylcytidine 5′-triphosphate
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    5-Methylcytidine 5′-triphosphate

    CAS:
    5-Methylcytidine 5′-triphosphate (5-Methyl-CTP), a modified nucleoside triphosphate, enhances translational properties and stability while reducing innate
    Fórmula:C10H18N3O14P3
    Cor e Forma:Solid
    Peso molecular:497.18

    Ref: TM-T74584

  • Stigmatellin
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    Stigmatellin

    CAS:
    <p>Stigmatellin is an antibiotic derived from the cell mass of the myxobacterium, effective against yeasts (yeasts), filamentous fungi (filamentous fungi), and several Gram-positive bacteria (Gram-positive bacteria). Additionally, it serves as a potent inhibitor of photosynthetic electron (photosynthetic electron) transfer. Stigmatellin utilizes various sugars, polysaccharides, and acids from the citric acid cycle as substrates, inhibiting RNA and protein synthesis. It has two different inhibitory sites: one located on the reducing side of photosystem II and the other at the cytochrome b6/f complex. Stigmatellin holds potential for use in antimicrobial and photosynthesis research.</p>
    Fórmula:C30H42O7
    Cor e Forma:Solid
    Peso molecular:514.65

    Ref: TM-TN8168

  • CDK5-IN-1
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    CDK5-IN-1

    CAS:
    CDK5-IN-1: Potent CDK5 inhibitor (<10 nM) used in kidney disease research.
    Fórmula:C24H25FN6O3S
    Cor e Forma:Solid
    Peso molecular:496.56

    Ref: TM-T40263

  • c-Myc inhibitor 7
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    c-Myc inhibitor 7

    CAS:
    c-Myc inhibitor 7 degrades c-MYC, CK1α, GSPT1, IKZF1/2/3 proteins in tumors, for research on related diseases.
    Fórmula:C35H30N6O5
    Cor e Forma:Soild
    Peso molecular:614.65

    Ref: TM-T72040

  • 11H-Benzo[a]carbazole
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    11H-Benzo[a]carbazole

    CAS:
    11H-Benzo[a]carbazole is a kinesin-like protein KIF11 inhibitor that can inhibit the viability of HeLa cells.
    Fórmula:C16H11N
    Pureza:99.14%
    Cor e Forma:Solid
    Peso molecular:217.27

    Ref: TM-TN9686

  • Cytidine 5'-diphosphate trisodium salt
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    Cytidine 5'-diphosphate trisodium salt

    CAS:
    <p>CDP, a trisodium salt, helps synthesize DNA/RNA by aiding phosphoryl transfer from ATP to CMP via UMPK.</p>
    Fórmula:C9H15N3Na3O11P2
    Pureza:99.55%
    Cor e Forma:White Crystalline Powder
    Peso molecular:472.15

    Ref: TM-T40426

  • Logotipo do CymitQuimica
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    PKMYT1-IN-3

    PKMYT1-IN-3 (compound 8ma) is a potent, selective inhibitor of PKMYT1, demonstrating an IC50 of 16.5 nM and exhibiting antitumor activity.
    Fórmula:C24H26FN5O2
    Cor e Forma:Solid
    Peso molecular:435.49

    Ref: TM-T200211

  • Logotipo do CymitQuimica
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    5-Methylcytidine 5′-triphosphate trisodium

    <p>5-Methylcytidine 5′-triphosphate trisodium (5-Methyl-CTP trisodium), a modified nucleoside triphosphate, enhances translational properties and stability, while</p>
    Fórmula:C10H15N3Na3O14P3
    Cor e Forma:Solid
    Peso molecular:563.13

    Ref: TM-T74585

  • Logotipo do CymitQuimica
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    2-Methylbutyrylcarnitine chloride

    2-Methylbutyrylcarnitine (chloride) acts as a gut microbial metabolite that targets integrin α2β1 on platelets, facilitating the activation of cytosolic phospholipase A2 (cPLA2) and enhancing platelet hyperresponsiveness. This compound further augments platelet hyperreactivity and promotes thrombus formation in mice. It is also characterized as a branched-chain acylcarnitine.
    Fórmula:C12H24ClNO4
    Cor e Forma:Solid
    Peso molecular:281.78

    Ref: TM-T200397

  • IV-361
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    IV-361

    CAS:
    IV-361, an orally active and selective CDK7 inhibitor with a Ki value of less than or equal to 50 nM, demonstrates potent anti-cancer activity (US20190256531A1
    Fórmula:C23H32FN5O2Si
    Cor e Forma:Solid
    Peso molecular:457.625

    Ref: TM-T39456

  • Logotipo do CymitQuimica
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    5-Aza-xylo-cytidine

    <p>5-Aza-xylo-cytidine, a purine analog with antitumor effects, inhibits DNA synthesis and induces apoptosis in lymphoid cancers.</p>
    Fórmula:C8H12N4O5
    Cor e Forma:Solid
    Peso molecular:244.2

    Ref: TM-T75220

  • FF-10502
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    FF-10502

    CAS:
    FF-10502, a pyrimidine analog of Gemcitabine, inhibits DNA polymerases α/β, targeting dormant cancer cells.
    Fórmula:C9H12FN3O3S
    Cor e Forma:Solid
    Peso molecular:261.27

    Ref: TM-T39290

  • Pseudouridimycin
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    Pseudouridimycin

    CAS:
    Pseudouridimycin: a C-nucleoside antibiotic, inhibits bacterial RNAP, targets Gram-negative and Gram-positive bacteria.
    Fórmula:C17H26N8O9
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:486.44

    Ref: TM-T16673

  • Logotipo do CymitQuimica
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    AURKA against 1

    <p>Compound Ac13, also termed AURKA against 1, acts as an inhibitor of the Aurora kinase (AURKA) with an IC50 of less than 0.5 nM, targeting the acetylation of endogenous lysine (K162) and exhibiting anti-tumor cell proliferation activity. The kinase activity of AURKA, acetylated at K162 and induced by AURKA against 1, is reversibly restored in HCT116 cells transfected with SIRT3.</p>
    Fórmula:C28H32FN9O2
    Cor e Forma:Solid
    Peso molecular:545.61

    Ref: TM-T89903

  • Anticancer agent 263
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    Anticancer agent 263

    Anticanceragent 263 (compound 7) is an effective anticancer agent. It binds with the G-quadruplex DNA (G4) sequence 22-mer Pu22 (a c-Myc DNA analog). As a structural modulator, Anticanceragent 263 significantly enhances the formation of protein α-helices and has the capacity to form a supramolecular network. Furthermore, Anticanceragent 263 exhibits no cytotoxicity.
    Fórmula:C13H20N2O6
    Cor e Forma:Solid
    Peso molecular:300.308

    Ref: TM-T204102

  • Logotipo do CymitQuimica
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    2'-Fluoro-2'-deoxy-arabinoadenosine 5'-triphosphate triethylamine

    2’-Fluoro-2’-deoxy-arabinoadenosine 5’-triphosphate (triethylamine) is a purine nucleoside analog with significant antitumor properties, particularly effective
    Fórmula:C34H75FN9O12P3
    Cor e Forma:Solid
    Peso molecular:913.93

    Ref: TM-T75207

  • αVβ8-IN-1
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    αVβ8-IN-1

    CAS:
    <p>αVβ8-IN-1 is an αVβ8 integrin inhibitor that suppresses the growth of multiple tumour cell lines (EMT6, CT26, KPC, TKCC-10).</p>
    Fórmula:C25H32ClN5O4
    Cor e Forma:Solid
    Peso molecular:502.01

    Ref: TM-T200044

  • Logotipo do CymitQuimica
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    Anti-EMMPRIN/CD147 Antibody

    Anti-EMMPRIN/CD147 Antibody is a human-derived antibody expressed in CHO cells, targeting Basigin. For an isotype control, refer to HumanIgG1kappa, Isotype Control.
    Cor e Forma:Odour Liquid

    Ref: TM-T9901A-803

  • JH-XVI-178
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    JH-XVI-178

    CAS:
    JH-XVI-178: potent CDK8/19 inhibitor with good pharmacokinetics, low clearance, moderate oral bioavailability.
    Fórmula:C22H22ClN7O
    Cor e Forma:Solid
    Peso molecular:435.92

    Ref: TM-T40280

  • Lorutengitide
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    Lorutengitide

    CAS:
    <p>Lorutengitide is a transcription-regulating peptide with antiproliferative activity.</p>
    Fórmula:C30H50N8O12
    Cor e Forma:Solid
    Peso molecular:714.764

    Ref: TM-TP3135