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Ciclo celular/Ponto de verificação

Ciclo celular/Ponto de verificação

Os inibidores do ciclo celular/ponto de verificação são compostos que interrompem a progressão normal do ciclo celular, particularmente em pontos de verificação regulatórios chave. Esses inibidores são cruciais para estudar a divisão celular, entender a proliferação de células cancerígenas e desenvolver terapias anticâncer. Ao direcionar fases específicas do ciclo celular, esses inibidores podem induzir a parada do ciclo celular, levando à apoptose ou senescência em células de divisão rápida. Na CymitQuimica, oferecemos uma ampla gama de inibidores de alta qualidade do ciclo celular/ponto de verificação para apoiar sua pesquisa em biologia do câncer, biologia celular e desenvolvimento de medicamentos.

Subcategorias de "Ciclo celular/Ponto de verificação"

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Foram encontrados 3485 produtos de "Ciclo celular/Ponto de verificação"

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  • Spirofylline
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    Spirofylline

    CAS:
    <p>Spirofylline is an agent of bronchodilator, has the potential for asthma and bronchitis and emphysema treatment.</p>
    Fórmula:C24H28N6O5
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:480.52

    Ref: TM-T13899

  • Netropsin dihydrochloride
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    Netropsin dihydrochloride

    CAS:
    <p>Netropsin dihydrochloride, a small MGB, blocks topoisomerase I/II, hindering cleavable complex stabilization.</p>
    Fórmula:C18H28Cl2N10O3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:503.39

    Ref: TM-T12209

  • Cdc7-IN-7
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    Cdc7-IN-7

    CAS:
    <p>Cdc7-IN-7 is a potent inhibitor of Cdc7 kinase.</p>
    Fórmula:C21H22N4O5
    Pureza:98.78%
    Cor e Forma:Solid
    Peso molecular:410.42

    Ref: TM-T10729

  • DHX9-IN-4
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    DHX9-IN-4

    CAS:
    <p>DHX9-IN-4 is an ATP-dependent RNA helicase DHX9 inhibitor used in cancer research.</p>
    Fórmula:C21H22ClN5O4S2
    Pureza:98.12%
    Cor e Forma:Solid
    Peso molecular:508.01

    Ref: TM-T86200

  • Nε-(1-Carboxyethyl)-L-lysine
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    Nε-(1-Carboxyethyl)-L-lysine

    CAS:
    <p>Nε-(1-Carboxyethyl)-L-lysine (CEL) is an advanced glycation end-product (AGE). Exposure to CEL reduces glutamate uptake and S100B secretion in the hippocampus.</p>
    Fórmula:C9H18N2O4
    Cor e Forma:Solid
    Peso molecular:218.25

    Ref: TM-T85157

  • Senexin C
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    Senexin C

    CAS:
    <p>Senexin C is a CDK8/19 inhibitor with anticancer activity.Senexin C inhibits the growth of MV4-11 leukemia cells.</p>
    Fórmula:C28H27N5O
    Pureza:98.06%
    Cor e Forma:Solid
    Peso molecular:449.55

    Ref: TM-T62702

  • CDK4/6-IN-15
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    CDK4/6-IN-15

    CAS:
    <p>CDK4/6-IN-15: Oral, selective CDK4/6 inhibitor, halts cancer cell growth, G1 arrest, suppresses Rb phosphorylation.</p>
    Fórmula:C21H27FN8S
    Cor e Forma:Solid
    Peso molecular:442.56

    Ref: TM-T72928

  • Senexin A hydrochloride
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    Senexin A hydrochloride

    CAS:
    <p>Senexin A hydrochloride functions as a selective inhibitor of CDK8/19, with an IC 50 of 280 nM for CDK8, and specifically inhibits p21-induced transcription without affecting other biological effects of p21. Additionally, it suppresses CMV-GFP induction and the stimulatory activity of the consensus NF-κB-dependent promoters [1] [2].</p>
    Fórmula:C17H15ClN4
    Cor e Forma:Solid
    Peso molecular:310.78

    Ref: TM-T84893

  • Galidesivir hydrochloride
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    Galidesivir hydrochloride

    CAS:
    <p>Galidesivir hydrochloride is an inhibitor of viral RNA-dependent RNA polymerase (RdRp). It inhibits SARS-CoV-2 by tightly binding to its RdRp.</p>
    Fórmula:C11H16ClN5O3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:301.73

    Ref: TM-T10491L

  • EHT 5372
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    EHT 5372

    CAS:
    <p>EHT 5372 inhibits DYRK kinases; IC50: 0.22-221 nM for DYRK1A/B, DYRK2/3, CLK1/2/4, GSK-3α/β.</p>
    Fórmula:C17H11Cl2N5OS
    Cor e Forma:Solid
    Peso molecular:404.27

    Ref: TM-T61985

  • Integrin Antagonists 27
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    Integrin Antagonists 27

    CAS:
    <p>Integrin Antagonists 27 is a small molecule integrin αvβ3 antagonist. It has a binding affinity of 18 nM and as a novel anticancer agent.</p>
    Fórmula:C24H20N4O5
    Cor e Forma:Solid
    Peso molecular:444.44

    Ref: TM-T15584

  • OXA-06 hydrochloride
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    OXA-06 hydrochloride

    CAS:
    <p>OXA-06 hydrochloride, an ATP-competitive ROCK inhibitor, impedes anchorage-dependent growth and invasion in non-small cell lung cancer cell lines. It effectively inhibits cofilin phosphorylation without inducing apoptosis [1].</p>
    Fórmula:C21H20Cl2FN3
    Cor e Forma:Solid
    Peso molecular:404.31

    Ref: TM-T84882

  • Riviciclib
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    Riviciclib

    CAS:
    <p>Riviciclib, a CDK inhibitor (CDK9/T1, CDK4/D1, CDK1/B), has IC50s: 20, 63, 79 nM respectively, and fights cisplatin-resistant tumors.</p>
    Fórmula:C21H20ClNO5
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:401.84

    Ref: TM-T12737

  • αvβ6 integrin inhibitor 2
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    αvβ6 integrin inhibitor 2

    CAS:
    <p>αvβ6 Integrin Inhibitor 2 is a potent inhibitor of αvβ6 integrin, demonstrating an inhibition concentration (IC50) of 96.5 nM.</p>
    Fórmula:C21H30N4O3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:386.49

    Ref: TM-T79140

  • ON 108600
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    ON 108600

    CAS:
    <p>ON 108600 is a chemical inhibitor targeting CK2 (Casein Kinase 2), TNIK, and DYRK1, demonstrating IC50 values of 0.016 μM and 0.007 μM for DYRK1A and DYRK1B, 0.</p>
    Fórmula:C22H14Cl2N2O6S2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:537.39

    Ref: TM-T79908

  • Cdc7-IN-12
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    Cdc7-IN-12

    CAS:
    <p>Cdc7-IN-12, a sub-1 nM CDC7 inhibitor, may aid cancer research; hinders COLO205 cell growth (IC50: 100-1000 nM).</p>
    Fórmula:C16H14N2O2S
    Cor e Forma:Solid
    Peso molecular:298.36

    Ref: TM-T60659

  • Inixaciclib
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    Inixaciclib

    CAS:
    <p>Inixaciclib is a potent CDK inhibitor, can be used to research anticancer.</p>
    Fórmula:C26H30F2N6O
    Cor e Forma:Solid
    Peso molecular:480.55

    Ref: TM-T69662

  • Tirofiban HCl
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    Tirofiban HCl

    CAS:
    <p>Tirofiban HCl is an antagonist of platelet glycoprotein-IIb/IIIa receptor.</p>
    Fórmula:C22H37ClN2O5S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:477.06

    Ref: TM-T20552

  • GSK2646264
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    GSK2646264

    CAS:
    <p>GSK2646264 (Compound 44) inhibits SYK (pIC50=7.1) and kinases like LCK, LRRK2; penetrates skin.</p>
    Fórmula:C24H26N2O2
    Cor e Forma:Solid
    Peso molecular:374.48

    Ref: TM-T61527

  • CDK7-IN-22
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    CDK7-IN-22

    CAS:
    <p>CDK7-IN-22 (compound 101) is a selective CDK7 inhibitor that exhibits antitumor activity, demonstrating specificity for CDK7 [1].</p>
    Fórmula:C22H25F3N6
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:430.47

    Ref: TM-T79169