CymitQuimica logo
Ciclo celular/Ponto de verificação

Ciclo celular/Ponto de verificação

Os inibidores do ciclo celular/ponto de verificação são compostos que interrompem a progressão normal do ciclo celular, particularmente em pontos de verificação regulatórios chave. Esses inibidores são cruciais para estudar a divisão celular, entender a proliferação de células cancerígenas e desenvolver terapias anticâncer. Ao direcionar fases específicas do ciclo celular, esses inibidores podem induzir a parada do ciclo celular, levando à apoptose ou senescência em células de divisão rápida. Na CymitQuimica, oferecemos uma ampla gama de inibidores de alta qualidade do ciclo celular/ponto de verificação para apoiar sua pesquisa em biologia do câncer, biologia celular e desenvolvimento de medicamentos.

Subcategorias de "Ciclo celular/Ponto de verificação"

Exibir 10 mais subcategorias

Foram encontrados 3485 produtos de "Ciclo celular/Ponto de verificação"

Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
produtos por página.
  • ROCK-IN-10
    Targetmol
    + Info

    ROCK-IN-10

    CAS:
    <p>ROCK-IN-10 (compound 50) serves as a powerful inhibitor of ROCK, exhibiting IC50 values of 6 nM for ROCK1 and 4 nM for ROCK2, respectively. It demonstrates over 100-fold selectivity towards ROCK1 and ROCK2 when compared to other kinases [1].</p>
    Fórmula:C25H25N5O3
    Cor e Forma:Solid
    Peso molecular:443.507

    Ref: TM-T84502

  • Fosfluridine tidoxil
    Targetmol
    + Info

    Fosfluridine tidoxil

    CAS:
    <p>Fosfluridine tidoxil, a thymidylate synthase inhibitor, is used potentially for the treatment of colorectal cancer, and breast cancer.</p>
    Fórmula:C34H62FN2O10PS
    Cor e Forma:Solid
    Peso molecular:740.9

    Ref: TM-T27349

  • AAPK-25
    Targetmol
    + Info

    AAPK-25

    CAS:
    <p>AAPK-25, a dual Aurora/PLK inhibitor, disrupts mitosis, induces apoptosis, and has antitumor properties.</p>
    Fórmula:C21H13Cl2N3O2S
    Pureza:97.05%
    Cor e Forma:Solid
    Peso molecular:442.32

    Ref: TM-T10215

  • CDK9-IN-23
    Targetmol
    + Info

    CDK9-IN-23

    CAS:
    <p>CDK9-IN-23 (Example 4) is a potent inhibitor of CDK9, exhibiting an IC50 value of less than 20 nM [1].</p>
    Fórmula:C22H25ClN4O3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:428.91

    Ref: TM-T79037

  • WRN inhibitor 2
    Targetmol
    + Info

    WRN inhibitor 2

    CAS:
    <p>WRN Inhibitor 2 (example 118), a potent inhibitor of the WRN (Werner Syndrome ATP-dependent helicase enzyme), exhibits a pIC50 value of 7.0 or greater [1].</p>
    Fórmula:C15H11F3N2O5S2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:420.38

    Ref: TM-T79178

  • Sapacitabine
    Targetmol
    + Info

    Sapacitabine

    CAS:
    <p>Sapacitabine (CS682) is a nucleoside analog precursor with anticancer activity used in the study of leukemia.</p>
    Fórmula:C26H42N4O5
    Pureza:98.82%
    Cor e Forma:Solid
    Peso molecular:490.64

    Ref: TM-TQ0245

  • PDD00031705
    Targetmol
    + Info

    PDD00031705

    CAS:
    <p>PDD00031705 is a benzimidazolone core cell-inactive Poly (ADP-ribose) glycohydrolase (PARG) inhibitor.</p>
    Fórmula:C20H22N6O3S3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:490.62

    Ref: TM-T12388

  • BMT-090605
    Targetmol
    + Info

    BMT-090605

    CAS:
    <p>BMT-090605: AAK1 inhibitor (IC50=0.6 nM), also affects BIKE (45 nM) and GAK (60 nM), has antinociceptive properties.</p>
    Fórmula:C21H24N4O2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:364.44

    Ref: TM-T14691

  • NTRC 0066-0
    Targetmol
    + Info

    NTRC 0066-0

    CAS:
    <p>NTRC 0066-0 is a TTK inhibitor that can be used in cancer research.</p>
    Fórmula:C33H39N7O2
    Pureza:98.30%
    Cor e Forma:Solid
    Peso molecular:565.71

    Ref: TM-T28216

  • PLK4-IN-4
    Targetmol
    + Info

    PLK4-IN-4

    CAS:
    <p>PLK4-IN-4 (compound 22), a potent inhibitor of PLK4, exhibits an IC50 value of 7.9 nM, suggesting its potential use in cancer research [1].</p>
    Fórmula:C21H23F2N9
    Cor e Forma:Solid
    Peso molecular:439.46

    Ref: TM-T84697

  • WRN inhibitor 1
    Targetmol
    + Info

    WRN inhibitor 1

    CAS:
    <p>WRN Inhibitor 1 (example 7) is an inhibitor of the Werner Syndrome ATP-dependent helicase enzyme (WRN), selectively targeting its helicase domain.</p>
    Fórmula:C16H13FN2O4S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:348.35

    Ref: TM-T79107

  • PD-L1-IN-2
    Targetmol
    + Info

    PD-L1-IN-2

    CAS:
    <p>PD-L1-IN-2, a Naamidine J derivative, serves as a promising antineoplastic immunomodulator by hindering PD-L1 activity.</p>
    Fórmula:C33H38N4O6
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:586.68

    Ref: TM-T78053

  • CCT241533
    Targetmol
    + Info

    CCT241533

    CAS:
    <p>CCT241533 is an effective and selective ATP competitive inhibitor of CHK2 (Ki: 1.16 nM; IC50: 3 nM).</p>
    Fórmula:C23H27FN4O4
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:442.48

    Ref: TM-T10718

  • ICAM-1-IN-1
    Targetmol
    + Info

    ICAM-1-IN-1

    CAS:
    <p>ICAM-1-IN-1 is a potent and selective E-selectin(IC50 = 7 nM) and ICAM-1(IC50 = 5 nM) inhibitor.</p>
    Fórmula:C15H11BrN2O2S
    Pureza:99.67%
    Cor e Forma:Solid
    Peso molecular:363.23

    Ref: TM-T13147

  • SC-52012
    Targetmol
    + Info

    SC-52012

    CAS:
    <p>SC-52012 is a novel and potent fibrinogen receptor antagonist, an RGD mimetic, which inhibits platelet aggregation.</p>
    Fórmula:C25H30N4O6
    Pureza:97.20%
    Cor e Forma:Solid
    Peso molecular:482.53

    Ref: TM-T12857

  • USP7-IN-12
    Targetmol
    + Info

    USP7-IN-12

    CAS:
    <p>USP7-IN-12 (compound 1) is a potent, orally active inhibitor of Usp7, exhibiting an IC50 of 3.67 nM and demonstrating antiproliferative activity [1].</p>
    Fórmula:C29H28ClFN4O2S
    Cor e Forma:Solid
    Peso molecular:551.07

    Ref: TM-T79164

  • DNA gyrase B-IN-3
    Targetmol
    + Info

    DNA gyrase B-IN-3

    CAS:
    <p>DNA gyrase B-IN-3 (Compound A), with an IC50 of less than 10 nM, acts as an inhibitor of bacterial DNA gyrase B and exhibits antibacterial activity against Gram</p>
    Fórmula:C14H9Cl2N3O4S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:386.21

    Ref: TM-T78776

  • Kif15-IN-2
    Targetmol
    + Info

    Kif15-IN-2

    CAS:
    <p>Kif15-IN-2 is a kinesin Kif15 inhibitor with potential anticancer activity and can be used in prostate cancer research.</p>
    Fórmula:C20H20N6O4S
    Pureza:98.17%
    Cor e Forma:Solid
    Peso molecular:440.48

    Ref: TM-T11759

  • CI 972 anhydrous
    Targetmol
    + Info

    CI 972 anhydrous

    CAS:
    <p>CI 972 anhydrous is an inhibitor of purine nucleoside phosphorylase (PNP) (Ki: 0.83 μM) used as a T cell-selective immunosuppressive agent.</p>
    Fórmula:C11H12ClN5OS
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:297.76

    Ref: TM-T14964

  • Myt1-IN-2
    Targetmol
    + Info

    Myt1-IN-2

    CAS:
    <p>Myt1-IN-2, a highly potent Myt1 inhibitor, exhibits remarkable anticancer properties with an IC50 value below 10 nM (WO2021195782A1; compound 28) [1].</p>
    Fórmula:C18H16N6O2S
    Cor e Forma:Solid
    Peso molecular:380.42

    Ref: TM-T61615