Ciclo celular/Ponto de verificação

Os inibidores do ciclo celular/ponto de verificação são compostos que interrompem a progressão normal do ciclo celular, particularmente em pontos de verificação regulatórios chave. Esses inibidores são cruciais para estudar a divisão celular, entender a proliferação de células cancerígenas e desenvolver terapias anticâncer. Ao direcionar fases específicas do ciclo celular, esses inibidores podem induzir a parada do ciclo celular, levando à apoptose ou senescência em células de divisão rápida. Na CymitQuimica, oferecemos uma ampla gama de inibidores de alta qualidade do ciclo celular/ponto de verificação para apoiar sua pesquisa em biologia do câncer, biologia celular e desenvolvimento de medicamentos.

Subcategorias de "Ciclo celular/Ponto de verificação"

Exibir 10 mais subcategorias

Foram encontrados 3764 produtos de "Ciclo celular/Ponto de verificação"

Pureza (%)

100

produtos por página.

+ Info
GS-443902 trisodium
CAS:
- 1355050-21-3
GS-443902 trisodium, a strong RdRp blocker, inhibits RSV/HCV with IC50 of 1.1/5 μM and is Remdesivir's active form.
Fórmula:C₁₂H₁₆N₅O₁₃P₃·xNa
Cor e Forma:Solid
Ref: TM-T38761
+ Info
PLK1-IN-2
CAS:
- 2640254-52-8
PLK1-IN-2 is a PLK1 kinase inhibitor with an IC 50 value of 0.384 μM.
Fórmula:C₂₄H₂₇FN₈OS
Cor e Forma:Solid
Peso molecular:494.59
Ref: TM-T40265
+ Info
11H-Benzo[a]carbazole
CAS:
- 239-01-0
11H-Benzo[a]carbazole is a kinesin-like protein KIF11 inhibitor that can inhibit the viability of HeLa cells.
Fórmula:C₁₆H₁₁N
Pureza:99.14%
Cor e Forma:Solid
Peso molecular:217.27
Ref: TM-TN9686
+ Info
Uridine-5-oxo-acetyl-(9-fluorenylmethyl) ester
Uridine analogue with antitumor effects; inhibits DNA synthesis, induces apoptosis in lymphoid cancers.
Fórmula:C₂₄H₂₄N₂O₉
Cor e Forma:Solid
Peso molecular:484.46
Ref: TM-T75087
+ Info
Heliquinomycin
CAS:
- 178182-49-5
Heliquinomycin, a Streptomyces metabolite, inhibits DNA helicase (Ki=6.8 μM) and fights Gram-positive bacteria and various cancer cells.
Fórmula:C₃₃H₃₀O₁₇
Cor e Forma:Solid
Peso molecular:698.586
Ref: TM-T36748
+ Info
3'-Deoxyuridine-5'-triphosphate trisodium
3'-dUTP trisodium, a nucleotide analogue, inhibits RNA polymerases I/II and UTP integration into RNA (Ki=2.0 μM).
Fórmula:C₉H₁₂N₂Na₃O₁₄P₃
Cor e Forma:Soild
Peso molecular:534.08
Ref: TM-T35658
+ Info
(1S,3R,5R)-PIM447 dihydrochloride
(1S,3R,5R)-PIM447 (dihydrochloride) an inhibitor of PIM(IC50 of 0.095 μM for Pim1, 0.522 μM for Pim2 and 0.369 μM for Pim3).
Fórmula:C₂₄H₂₅Cl₂F₃N₄O
Pureza:98%
Cor e Forma:Solid
Peso molecular:513.38
Ref: TM-T13425
+ Info
GK13S
G13KS: UCHL1 ligand, deubiquitinase inhibitor; reduces monoubiquitin in glioblastoma cells.
Fórmula:C₂₁H₂₂N₆O₂
Cor e Forma:Solid
Peso molecular:390.44
Ref: TM-T75182
+ Info
Chrysomycin A
CAS:
- 82196-88-1
Chrysomycin A is an antibiotic that can be derived from Streptomyces.
Fórmula:C₂₈H₂₈O₉
Cor e Forma:Solid
Peso molecular:508.52
Ref: TM-T36467
+ Info
UnyLinker 12 TEA
UnyLinker 12 TEA is a versatile linker used in the synthesis of oligoribonucleotides.
Fórmula:C₃₉H₃₅NO₁₀C₆H₁₅N
Cor e Forma:Solid
Peso molecular:778.34655
Ref: TM-TSW-00947
+ Info
5'-O-DMT-Bz-rC
CAS:
- 81246-76-6
5’-O-DMT-Bz-Rc is a modified nucleoside and can be used to synthesize DNA or RNA.
Fórmula:C₃₇H₃₅N₃O₈
Cor e Forma:Solid
Peso molecular:649.69
Ref: TM-T37135
+ Info
JB300
CAS:
- 3038446-90-8
JB300 is a PROTAC-based compound that serves as a highly selective degrader of Aurora A, with a DC50 of 30 nM. It is utilized in cancer research. JB300 comprises the PROTAC target protein ligand MK-5108 [pink part], E3 ligase ligand Thalidomide-O-COOH [blue part], and PROTAC Linker Boc-NH-PEG2-C2-NH2 [black part]. The conjugate of the E3 ubiquitin ligase ligand and linker is Thalidomide-O-COOH-NH2-C2-PEG2-NH-Boc.
Fórmula:C₄₃H₄₅ClFN₇O₁₀S
Cor e Forma:Solid
Peso molecular:906.375
Ref: TM-T204223
+ Info
Anti-EMMPRIN/CD147 Antibody
Anti-EMMPRIN/CD147 Antibody is a human-derived antibody expressed in CHO cells, targeting Basigin. For an isotype control, refer to HumanIgG1kappa, Isotype Control.
Cor e Forma:Odour Liquid
Ref: TM-T9901A-803
+ Info
m7GpppCpG
CAS:
- 2638447-78-4
m7GpppCpG, a trinucleotide cap analogue, is used for synthesizing RNA with cap 0 or cap 1 structures.
Fórmula:C₃₀H₄₁N₁₃O₂₅P₄
Cor e Forma:Solid
Peso molecular:1107.61
Ref: TM-T74480
+ Info
Lorutengitide
CAS:
- 2559326-61-1
Lorutengitide is a transcription-regulating peptide with antiproliferative activity.
Fórmula:C₃₀H₅₀N₈O₁₂
Cor e Forma:Solid
Peso molecular:714.764
Ref: TM-TP3135
+ Info
5'-O-TBDMS-dA
CAS:
- 51549-30-5
5’-O-TBDMS-dA is a modified nucleoside and can be used to synthesize DNA or RNA.
Fórmula:C₁₆H₂₇N₅O₃Si
Cor e Forma:Solid
Peso molecular:365.509
Ref: TM-T37143
+ Info
Anticancer agent 263
Anticanceragent 263 (compound 7) is an effective anticancer agent. It binds with the G-quadruplex DNA (G4) sequence 22-mer Pu22 (a c-Myc DNA analog). As a structural modulator, Anticanceragent 263 significantly enhances the formation of protein α-helices and has the capacity to form a supramolecular network. Furthermore, Anticanceragent 263 exhibits no cytotoxicity.
Fórmula:C₁₃H₂₀N₂O₆
Cor e Forma:Solid
Peso molecular:300.308
Ref: TM-T204102
+ Info
WAY-647802
CAS:
- 852225-20-8
WAY-647802 is a CDK inhibitor.
Fórmula:C₁₁H₁₄N₄O₃
Pureza:99.53%
Cor e Forma:Solid
Peso molecular:250.25
Ref: TM-T9971
+ Info
Obtustatin
Potent α1β1 integrin inhibitor, 0.8 nM IC50 for IV collagen binding. Selective over other integrins. Inhibits FGF2 angiogenesis; antitumor in mouse models.
Fórmula:C₁₈₄H₂₈₄N₅₂O₅₇S₈
Pureza:98%
Cor e Forma:Solid
Peso molecular:4393.07
Ref: TM-TP1974
+ Info
Carboxy pyridostatin trifluoroacetate salt
Carboxy pyridostatin trifluoroacetate salt exhibits higher molecular specificity for RNA over DNA G4s.
Fórmula:C₃₇H₃₅F₃N₁₀O₉
Pureza:98%
Cor e Forma:Solid
Peso molecular:820.73
Ref: TM-T13595