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Ciclo celular/Ponto de verificação

Ciclo celular/Ponto de verificação

Os inibidores do ciclo celular/ponto de verificação são compostos que interrompem a progressão normal do ciclo celular, particularmente em pontos de verificação regulatórios chave. Esses inibidores são cruciais para estudar a divisão celular, entender a proliferação de células cancerígenas e desenvolver terapias anticâncer. Ao direcionar fases específicas do ciclo celular, esses inibidores podem induzir a parada do ciclo celular, levando à apoptose ou senescência em células de divisão rápida. Na CymitQuimica, oferecemos uma ampla gama de inibidores de alta qualidade do ciclo celular/ponto de verificação para apoiar sua pesquisa em biologia do câncer, biologia celular e desenvolvimento de medicamentos.

Subcategorias de "Ciclo celular/Ponto de verificação"

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Foram encontrados 3477 produtos de "Ciclo celular/Ponto de verificação"

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  • Haspin-IN-2
    Targetmol
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    Haspin-IN-2

    CAS:
    <p>Haspin-IN-2 is a potent haspin inhibitor (IC50: 50 nM) and also inhibits CLK1 (IC50: 445 nM) and DYRK1A (IC50: 917 nM).</p>
    Fórmula:C12H8N4O3
    Cor e Forma:Solid
    Peso molecular:256.22

    Ref: TM-T60394

  • Fradafiban
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    Fradafiban

    CAS:
    <p>Fradafiban binds to the human platelet GP IIb/IIIa complex with a Kd value of 148 nM. Fradafiban is a non-polypeptide platelet glycoprotein IIb/IIIa antagonist.</p>
    Fórmula:C20H21N3O4
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:367.40

    Ref: TM-T11322

  • Logotipo do CymitQuimica
    Targetmol
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    2'-F-UMP

    CAS:
    <p>2'-F-UMP is a nucleotide analogue used in the synthesis of oligonucleotides.</p>
    Fórmula:C9H12FN2O8P
    Peso molecular:326.17

    Ref: TM-TSW-00948

  • 6-B345TTQ
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    6-B345TTQ

    CAS:
    <p>6-B345TTQ is an α4 integrin inhibitor that can impede the interaction between α4 and Leupaxin. This compound is applicable for studies focused on inflammation research.</p>
    Fórmula:C22H20BrNO4
    Cor e Forma:Solid
    Peso molecular:442.303

    Ref: TM-T204244

  • Galidesivir
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    Galidesivir

    CAS:
    <p>Galidesivir (BCX4430) is an antiviral compound that inhibits viral RNA-dependent RNA polymerase (RdRp) activity and reduces lung infections in infected animals.</p>
    Fórmula:C11H15N5O3
    Pureza:96.73% - 99.13%
    Cor e Forma:Solid
    Peso molecular:265.27

    Ref: TM-T10491

  • Des-ethyl-carafiban
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    Des-ethyl-carafiban

    CAS:
    <p>Des-ethyl-carafiban (Compound 44) is an antagonist of the fibrinogen receptor, effectively inhibiting platelet aggregation induced by various agonists. It is useful for research in thrombotic diseases.</p>
    Fórmula:C22H23N5O5
    Cor e Forma:Solid
    Peso molecular:437.448

    Ref: TM-T206156

  • 2′-O-MOE-AMP
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    2′-O-MOE-AMP

    CAS:
    <p>2′-O-MOE-AMP is a nucleotide analogue used in the synthesis of oligonucleotides.</p>
    Fórmula:C13H20N5O8P
    Cor e Forma:Solid
    Peso molecular:405.30

    Ref: TM-TSW-00946

  • CDK4/6-IN-13
    Targetmol
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    CDK4/6-IN-13

    CAS:
    <p>Compounds 10B and 10C: potent cdk4/6 inhibitors with low nM activity, great antiproliferative effects, excellent metabolism, and good pharmacokinetics.</p>
    Fórmula:C25H29N7O
    Cor e Forma:Solid
    Peso molecular:443.54

    Ref: TM-T62605

  • Aurora B inhibitor 1
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    Aurora B inhibitor 1

    CAS:
    <p>Aurora B inhibitor 1 is an Aurora B (Aurora-1) inhibitor (Ki &lt;0.010 uM) with potential anticancer activity for cancer research.</p>
    Fórmula:C25H26ClF2N7O2
    Pureza:98.37%
    Cor e Forma:Solid
    Peso molecular:529.97

    Ref: TM-T12010

  • PD-1/PD-L1-IN-53
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    PD-1/PD-L1-IN-53

    CAS:
    <p>PD-1/PD-L1-IN-53 (compound B3) serves as an inhibitor targeting both the PD-1/PD-L1 and VISTA signaling pathways. It is utilized in cancer research.</p>
    Fórmula:C31H37N3O4
    Cor e Forma:Solid
    Peso molecular:515.64

    Ref: TM-T200774

  • Logotipo do CymitQuimica
    Targetmol
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    2'-F-AMP

    CAS:
    <p>2'-F-AMP is a nucleotide analogue used in the synthesis of oligonucleotides.</p>
    Fórmula:C10H13FN5O6P
    Peso molecular:349.21

    Ref: TM-TSW-00945

  • CDK2-IN-30
    Targetmol
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    CDK2-IN-30

    CAS:
    <p>CDK2-IN-30 (Formula (I)) is a CDK2 inhibitor with an IC50 of ≤20 nM, utilized primarily in tumor research.</p>
    Fórmula:C18H25N7O3S
    Cor e Forma:Solid
    Peso molecular:419.50

    Ref: TM-T200706

  • LNA-UTP
    Targetmol
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    LNA-UTP

    CAS:
    <p>LNA-UTP is a nucleotide analogue used in the synthesis of oligonucleotides.</p>
    Fórmula:C10H15N2O15P3
    Cor e Forma:Solid
    Peso molecular:496.15

    Ref: TM-TSW-00943

  • BWC0977
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    BWC0977

    CAS:
    <p>BWC0977 is an effective topoisomerase inhibitor that disrupts bacterial DNA replication by targeting both DNA gyrase and topoisomerase IV. The minimum inhibitory concentration (MIC90) of BWC0977 against MDR (multi-drug resistant) Gram-negative bacteria ranges from 0.03 to 2 µg/mL.</p>
    Fórmula:C22H21FN6O5
    Cor e Forma:Solid
    Peso molecular:468.44

    Ref: TM-T201074

  • DYRK1-IN-1
    Targetmol
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    DYRK1-IN-1

    CAS:
    <p>DYRK1-IN-1: Selective DYRK1A inhibitor with IC50 of 220 nM, good permeability, CNS penetrant for research, no P-glycoprotein issues.</p>
    Fórmula:C12H12N6
    Cor e Forma:Solid
    Peso molecular:240.26

    Ref: TM-T60334

  • GSK3-IN-10
    Targetmol
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    GSK3-IN-10

    CAS:
    <p>GSK3-IN-10 (Compound 4) is a multi-target inhibitor primarily affecting GSK3α and GSK3β with IC50 values of 1.0 nM and 2.0 nM, respectively. It inhibits the activation of β-catenin, enhances neuronal survival, and provides protective effects against endoplasmic reticulum stress.</p>
    Fórmula:C17H18F2N4O3
    Cor e Forma:Solid
    Peso molecular:364.347

    Ref: TM-T206481

  • Logotipo do CymitQuimica
    Targetmol
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    Antitumor agent-74

    <p>Antitumor agent-74, a quinazoline derivative, inhibits DNA, arrests cell cycle, and induces apoptosis with agent-75.</p>
    Fórmula:C26H23FN6
    Cor e Forma:Solid
    Peso molecular:438.5

    Ref: TM-T62509

  • Pseudouridine 5'-OTBDPS
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    Pseudouridine 5'-OTBDPS

    CAS:
    <p>Pseudouridine5'-OTBDPS [5-(5-O-TBDPS-β-D-ribofuranosyl)uracil] is an intermediate of Pseudouridine.</p>
    Fórmula:C25H30N2O6Si
    Cor e Forma:Solid
    Peso molecular:482.60

    Ref: TM-TSW-00962

  • N6-Benzoyl-2'-deoxy-3'-O-DMT-adenosine
    Targetmol
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    N6-Benzoyl-2'-deoxy-3'-O-DMT-adenosine

    CAS:
    <p>N6-Benzoyl-2'-deoxy-3'-O-DMT-adenosine is a nucleoside analog that resembles the natural nucleotide adenosine in structure. It acts as an activator of ribonucleotide reductase, facilitating the conversion of ribonucleotides into deoxyribonucleotides.</p>
    Fórmula:C38H35N5O6
    Cor e Forma:Solid
    Peso molecular:657.714

    Ref: TM-T206424

  • RNAP-σ interaction inhibitor-1
    Targetmol
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    RNAP-σ interaction inhibitor-1

    CAS:
    <p>RNAP-σ interaction inhibitor-1 (compound 5d) acts as an inhibitor of the interaction between RNA polymerase and the sigma factor. It exhibits activity against Streptococci with a minimum inhibitory concentration (MIC) ranging from 1-2 µg/mL.</p>
    Fórmula:C19H11Cl3N2O6S2
    Cor e Forma:Solid
    Peso molecular:533.79

    Ref: TM-T207529