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Ciclo celular/Ponto de verificação

Ciclo celular/Ponto de verificação

Os inibidores do ciclo celular/ponto de verificação são compostos que interrompem a progressão normal do ciclo celular, particularmente em pontos de verificação regulatórios chave. Esses inibidores são cruciais para estudar a divisão celular, entender a proliferação de células cancerígenas e desenvolver terapias anticâncer. Ao direcionar fases específicas do ciclo celular, esses inibidores podem induzir a parada do ciclo celular, levando à apoptose ou senescência em células de divisão rápida. Na CymitQuimica, oferecemos uma ampla gama de inibidores de alta qualidade do ciclo celular/ponto de verificação para apoiar sua pesquisa em biologia do câncer, biologia celular e desenvolvimento de medicamentos.

Subcategorias de "Ciclo celular/Ponto de verificação"

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Foram encontrados 3764 produtos de "Ciclo celular/Ponto de verificação"

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  • Ac-MRGDH-NH2
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    Ac-MRGDH-NH2

    Ac-MRGDH-NH2 is a pentapeptide containing the RGD sequence. It is utilized in the synthesis of the diastereomeric prodrugs Λ- and Δ-[Ru(Ph2phen)2(κS,κN-(Ac-MRGDH-NH2))]Cl2. In these prodrugs, Ac-MRGDH-NH2 serves as a photolabile protecting group for the cytotoxic diruthenium aqua complexes [Ru(Ph2phen)2(OH2)2]2+, offering integrin targeting and photoactivation properties. Consequently, Ac-MRGDH-NH2 can be applied in studies exploring tumor-targeted photoactivatable chemotherapy.
    Fórmula:C25H41N11O8S
    Cor e Forma:Solid
    Peso molecular:655.727

    Ref: TM-TP3057

  • Pyrindamycin A
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    Pyrindamycin A

    CAS:
    Pyrindamycin A is an antibiotic that inhibits DNA synthesis,and shows antitumor activities against murine leukemia.
    Fórmula:C26H26ClN3O8
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:543.95

    Ref: TM-T12590

  • 11H-Benzo[a]carbazole
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    11H-Benzo[a]carbazole

    CAS:
    11H-Benzo[a]carbazole is a kinesin-like protein KIF11 inhibitor that can inhibit the viability of HeLa cells.
    Fórmula:C16H11N
    Pureza:99.14%
    Cor e Forma:Solid
    Peso molecular:217.27

    Ref: TM-TN9686

  • Barasertib
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    Barasertib

    CAS:
    AZD1152 is a pro-drug of Barasertib (AZD1152)-hQPA. Which is a highly selective Aurora B inhibitor with IC50 of 0.37 nM in a cell-free assay.
    Fórmula:C26H31FN7O6P
    Pureza:99.92% - 99.97%
    Cor e Forma:Solid
    Peso molecular:587.54

    Ref: TM-T14371

  • Logotipo do CymitQuimica
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    5'(R)-C-Methyl-5-fluorouridine

    5’(R)-C-Methyl-5-fluorouridine, a uridine analogue, possesses potential antiepileptic properties.
    Fórmula:C10H13FN2O6
    Cor e Forma:Solid
    Peso molecular:276.22

    Ref: TM-T75079

  • (S)-DI-87
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    (S)-DI-87

    CAS:
    <p>(S)-DI-87 is an isomer of DI-87, a oral dCK inhibitor，reduce dNTP production and cell cycle arrest. significantly inhibits tumor growth with thymidine.</p>
    Fórmula:C23H30N6O3S2
    Pureza:99.42%
    Cor e Forma:Soild
    Peso molecular:502.65

    Ref: TM-T39550L

  • Logotipo do CymitQuimica
    Targetmol
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    Anti-EMMPRIN/CD147 Antibody

    Anti-EMMPRIN/CD147 Antibody is a human-derived antibody expressed in CHO cells, targeting Basigin. For an isotype control, refer to HumanIgG1kappa, Isotype Control.
    Cor e Forma:Odour Liquid

    Ref: TM-T9901A-803

  • dUTP trisodium
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    dUTP trisodium

    CAS:
    <p>dUTP trisodium (Deoxyuridine triphosphate) is a deoxyuridine phosphate having a triphosphate group at the 5'-position and can be used for PCR.</p>
    Fórmula:C9H12N2Na3O14P3
    Pureza:100.00%
    Cor e Forma:Solid
    Peso molecular:534.09

    Ref: TM-T38427

  • Lorutengitide
    Targetmol
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    Lorutengitide

    CAS:
    <p>Lorutengitide is a transcription-regulating peptide with antiproliferative activity.</p>
    Fórmula:C30H50N8O12
    Cor e Forma:Solid
    Peso molecular:714.764

    Ref: TM-TP3135

  • Cytarabine triphosphate
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    Cytarabine triphosphate

    CAS:
    Ara-CTP, active Cytarabine metabolite, inhibits DNA synthesis, predicts leukemic chemosensitivity.
    Fórmula:C9H16N3O14P3
    Cor e Forma:Solid
    Peso molecular:483.16

    Ref: TM-T38718

  • Aclacinomycin A
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    Aclacinomycin A

    CAS:
    Aclacinomycin A has a wide range of applications in life science related research.
    Fórmula:C42H53NO15
    Pureza:99.43%
    Cor e Forma:Solid
    Peso molecular:811.87

    Ref: TM-T21502

  • Logotipo do CymitQuimica
    Targetmol
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    BLINK15

    BLINK15 is a blood-brain barrier-permeable Cdk5 inhibitor. It reduces CDK5 activity in CDK5/p35 (IC50= 29.34 nM) and CDK5/p25 (IC50= 12.08 nM) complexes. Additionally, BLINK15 exhibits antidiabetic and neuroprotective effects. It lowers blood glucose levels in type 2 diabetes (T2D) mice, enhances cognitive abilities, and diminishes neurodegenerative lesions.
    Cor e Forma:Odour Solid

    Ref: TM-T206737

  • 5'-O-TBDMS-Bz-dA
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    5'-O-TBDMS-Bz-dA

    CAS:
    5’-O-TBDMS-Bz-dA is a nucleoside with protective and modification effects.
    Fórmula:C23H31N5O4Si
    Cor e Forma:Solid
    Peso molecular:469.617

    Ref: TM-T37142

  • THK01
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    THK01

    CAS:
    THK01: ROCK2 inhibitor (IC50=5.7nM), less effective on ROCK1 (923nM). Hinders breast cancer spread via ROCK2-STAT3. For cancer research.
    Fórmula:C20H13N3O2
    Cor e Forma:Solid
    Peso molecular:327.34

    Ref: TM-T74808

  • 5'-O-DMT-Bz-rC
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    5'-O-DMT-Bz-rC

    CAS:
    <p>5’-O-DMT-Bz-Rc is a modified nucleoside and can be used to synthesize DNA or RNA.</p>
    Fórmula:C37H35N3O8
    Cor e Forma:Solid
    Peso molecular:649.69

    Ref: TM-T37135

  • 5'-ODMT cEt G Phosphoramidite (Amidite)
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    5'-ODMT cEt G Phosphoramidite (Amidite)

    CAS:
    5'-ODMT cEt G Amidite is a safe, effective nucleic acid analog with strong antisense activity.
    Fórmula:C46H56N7O9P
    Cor e Forma:Solid
    Peso molecular:881.95

    Ref: TM-T74703

  • Thailanstatin C
    Targetmol
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    Thailanstatin C

    CAS:
    Thailanstatin C from Burkholderia thailandensis blocks pre-mRNA splicing, IC50 6.84 μM.
    Fórmula:C30H46ClNO9
    Cor e Forma:Solid
    Peso molecular:600.15

    Ref: TM-T38890

  • Logotipo do CymitQuimica
    Targetmol
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    DSPE-PEG5000-cRGD

    DSPE-PEG5000-cRGD is a PEG compound composed of DSPE and an αvβ3 targeting peptide (cRGD). The cRGD peptide has the ability to specifically bind to the αvβ3 present on the surfaces of numerous cancer cells and new vascular cells. DSPE-PEG5000-cRGD is useful for drug delivery applications.
    Cor e Forma:Odour Solid

    Ref: TM-TCL-01154

  • Logotipo do CymitQuimica
    Targetmol
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    N1-Benzoyl pseudouridine

    N1-Benzoyl pseudouridine, a purine nucleoside analog, inhibits DNA synthesis and induces apoptosis to combat lymphoid cancers.
    Fórmula:C16H16N2O7
    Cor e Forma:Solid
    Peso molecular:348.31

    Ref: TM-T75038

  • Emicoron
    Targetmol
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    Emicoron

    CAS:
    Importazole is an inhibitor of the transport receptor importin-β. It specifically inhibits importin-β likely by altering its interaction with RanGTP.
    Fórmula:C52H58N6O4
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:831.05

    Ref: TM-T27258