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Ciclo celular/Ponto de verificação

Ciclo celular/Ponto de verificação

Os inibidores do ciclo celular/ponto de verificação são compostos que interrompem a progressão normal do ciclo celular, particularmente em pontos de verificação regulatórios chave. Esses inibidores são cruciais para estudar a divisão celular, entender a proliferação de células cancerígenas e desenvolver terapias anticâncer. Ao direcionar fases específicas do ciclo celular, esses inibidores podem induzir a parada do ciclo celular, levando à apoptose ou senescência em células de divisão rápida. Na CymitQuimica, oferecemos uma ampla gama de inibidores de alta qualidade do ciclo celular/ponto de verificação para apoiar sua pesquisa em biologia do câncer, biologia celular e desenvolvimento de medicamentos.

Subcategorias de "Ciclo celular/Ponto de verificação"

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Foram encontrados 3739 produtos de "Ciclo celular/Ponto de verificação"

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  • Logotipo do CymitQuimica
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    3'-β-C-Methyl-2-thiouridine

    3’-β-C-Methyl-2-thiouridine, a purine nucleoside analog, exhibits extensive antitumor activity, particularly against indolent lymphoid malignancies.
    Fórmula:C10H14N2O5S
    Cor e Forma:Solid
    Peso molecular:274.29

    Ref: TM-T75053

  • Logotipo do CymitQuimica
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    USP7-IN-15

    USP7-IN-15 (compound J21) is an inhibitor of USP7, exhibiting an IC50 value of 41.35 ± 2.16 nM.
    Cor e Forma:Odour Solid

    Ref: TM-T200570

  • 5'-O-DMT-PAC-dA
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    5'-O-DMT-PAC-dA

    CAS:
    <p>5’-O-DMT-PAC-dA can be used in the synthesis of oligoribonucleotides[1].</p>
    Fórmula:C39H37N5O7
    Cor e Forma:Solid
    Peso molecular:687.74

    Ref: TM-T37139

  • 6-Thioguanosine
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    6-Thioguanosine

    CAS:
    6-Thioguanosine (6-Mercaptoguanosine) is an active nucleoside and low molecular weight gel.6-Thioguanosine has immunosuppressive properties.
    Fórmula:C10H13N5O4S
    Pureza:97.05%
    Cor e Forma:Yellow-Green Powder
    Peso molecular:299.31

    Ref: TM-T20511

  • ROCK-IN-32
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    ROCK-IN-32

    CAS:
    ROCK-IN-32 is an effective Rho-kinase inhibitor.
    Fórmula:C20H17Cl2N3O2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:402.27

    Ref: TM-T24722

  • Thailanstatin C
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    Thailanstatin C

    CAS:
    Thailanstatin C from Burkholderia thailandensis blocks pre-mRNA splicing, IC50 6.84 μM.
    Fórmula:C30H46ClNO9
    Cor e Forma:Solid
    Peso molecular:600.15

    Ref: TM-T38890

  • CDK12-IN-6
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    CDK12-IN-6

    CAS:
    CDK12-IN-6, a pyrazolotriazine, strongly inhibits CDK12 (IC50 1.19 μM at 2 mM ATP), but not CDK2/Cyclin E or CDK9/Cyclin T1 (both IC50 >20 μM).
    Fórmula:C20H21F2N9
    Cor e Forma:Solid
    Peso molecular:425.448

    Ref: TM-T40289

  • Hemsloside Ma 1
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    Hemsloside Ma 1

    CAS:
    Hemsloside Ma 1 is a useful organic compound for research related to life sciences. The catalog number is T123850 and the CAS number is 95851-41-5.
    Fórmula:C47H74O18
    Cor e Forma:Solid
    Peso molecular:927.091

    Ref: TM-T123850

  • Chk1-IN-6
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    Chk1-IN-6

    CAS:
    <p>Chk1-IN-6 is a potent, selective, and orally bioavailable CHK1 inhibitor candidate.</p>
    Fórmula:C16H18F3N7
    Cor e Forma:Solid
    Peso molecular:365.364

    Ref: TM-T40091

  • Uridine triphosphate 13C9,15N2 sodium
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    Uridine triphosphate 13C9,15N2 sodium

    CAS:
    Uridine triphosphate 13C9,15N2 sodium is an isotopically labeled.UTP is a key in RNA synthesis molecule a substrate for RNA polymerase.
    Fórmula:C9H1415N2NaO15P3
    Cor e Forma:Solid
    Peso molecular:517.04

    Ref: TM-T36299

  • CBR-2092
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    CBR-2092

    CAS:
    CBR-2092 is a DNA-directed RNA polymerase and DNA topoisomerase inhibitor.
    Fórmula:C65H81FN6O15
    Cor e Forma:Solid
    Peso molecular:1205.388

    Ref: TM-T26963

  • Logotipo do CymitQuimica
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    Etrolizumab

    CAS:
    MEDI-578 is a CHO-expressed humanized monoclonal antibody targeting NGF/bNGF for the study of neurological and immune system disorders.
    Pureza:98.9% (SDS-PAGE); 96.6% (SEC-HPLC) - 98.9% (SDS-PAGE); 96.6% (SEC-HPLC)
    Cor e Forma:Liquid

    Ref: TM-T77154

  • Centaureidin
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    Centaureidin

    CAS:
    <p>Centaureidin is a useful organic compound for research related to life sciences. The catalog number is T125588 and the CAS number is 17313-52-9.</p>
    Fórmula:C18H16O8
    Cor e Forma:Solid
    Peso molecular:360.318

    Ref: TM-T125588

  • Psammaplin A
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    Psammaplin A

    CAS:
    <p>Psammaplin A: marine-derived, inhibits HDAC/DNA methyltransferases, strong DAC1 blocker (IC50=0.9nM), antimicrobial against Gram-positive bacteria, anticancer.</p>
    Fórmula:C22H24Br2N4O6S2
    Cor e Forma:Solid
    Peso molecular:664.38

    Ref: TM-T36303

  • 2'-Deoxyguanosine 5'-monophosphate (sodium salt hydrate)
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    2'-Deoxyguanosine 5'-monophosphate (sodium salt hydrate)

    CAS:
    dGMP is a substrate for DNA synthesis, phosphorylated to dGDP and dGTP, and linked to mitochondrial DNA depletion syndrome in humans.
    Fórmula:C10H14N5Na2O8P
    Cor e Forma:Solid
    Peso molecular:409.202

    Ref: TM-T35652

  • Logotipo do CymitQuimica
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    DSPE-PEG1000-cRGD

    DSPE-PEG1000-cRGD is a PEG compound composed of DSPE and the αvβ3-targeting peptide (cRGD). The cRGD peptide specifically binds to the αvβ3 receptors present on the surfaces of various cancer cells and angiogenic vascular cells. DSPE-PEG1000-cRGD is applicable in drug delivery.
    Cor e Forma:Odour Solid

    Ref: TM-TCL-01160

  • Logotipo do CymitQuimica
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    CDK9-IN-25

    <p>CDK9-IN-25 (compound 4a), an imidazopyrazine derivative, functions as a CDK9 inhibitor with an IC50 of 0.24 μM.</p>
    Fórmula:C15H16FN5
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:285.32

    Ref: TM-T79630

  • AG2034
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    AG2034

    CAS:
    AG2034 is an inhibitor of the glycinamide ribonucleotide formyltransferase (GARFT).
    Fórmula:C18H21N5O6S2
    Cor e Forma:Solid
    Peso molecular:467.52

    Ref: TM-T26572

  • Ficellomycin
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    Ficellomycin

    CAS:
    Ficellomycin is an aziridine antibiotic produced by Streptomyces ficellus. Which shows high in vitro activity against Gram-positive bacteria.
    Fórmula:C13H24N6O3
    Cor e Forma:Solid
    Peso molecular:312.37

    Ref: TM-T24063

  • 5'-O-DMT-rI
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    5'-O-DMT-rI

    CAS:
    5’-O-DMT-Ri can be used in the synthesis of oligoribonucleotides[1].
    Fórmula:C31H30N4O7
    Cor e Forma:Solid
    Peso molecular:570.59

    Ref: TM-T37140