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Ciclo celular/Ponto de verificação

Ciclo celular/Ponto de verificação

Os inibidores do ciclo celular/ponto de verificação são compostos que interrompem a progressão normal do ciclo celular, particularmente em pontos de verificação regulatórios chave. Esses inibidores são cruciais para estudar a divisão celular, entender a proliferação de células cancerígenas e desenvolver terapias anticâncer. Ao direcionar fases específicas do ciclo celular, esses inibidores podem induzir a parada do ciclo celular, levando à apoptose ou senescência em células de divisão rápida. Na CymitQuimica, oferecemos uma ampla gama de inibidores de alta qualidade do ciclo celular/ponto de verificação para apoiar sua pesquisa em biologia do câncer, biologia celular e desenvolvimento de medicamentos.

Subcategorias de "Ciclo celular/Ponto de verificação"

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Foram encontrados 3739 produtos de "Ciclo celular/Ponto de verificação"

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  • VPC-18005
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    VPC-18005

    CAS:
    <p>VPC-18005: a luciferase inhibitor that blocks ERG-induced transcription by binding ERG-ETS, hindering DNA attachment.</p>
    Fórmula:C15H17N3O3S
    Pureza:99.95%
    Cor e Forma:Soild
    Peso molecular:319.38

    Ref: TM-T60051

  • Cyclopentyluracil
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    Cyclopentyluracil

    CAS:
    Cyclopentyluracil is a carbocyclic analogue of uridine.
    Fórmula:C10H14N2O5
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:242.23

    Ref: TM-T19255

  • Logotipo do CymitQuimica
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    DNA Gyrase-IN-17

    DNA Gyrase-IN-17 (Compound 5C) is an inhibitor of DNA gyrase. It demonstrates significant antimicrobial activity against a range of Gram-positive and Gram-negative strains, including Enterococcus faecium, Escherichia coli, and Pseudomonas aeruginosa, with a MIC value of 62.5 μg/mL. By inhibiting bacterial DNA gyrase, DNA Gyrase-IN-17 disrupts DNA replication. This compound can be useful in the development of antibiotics, particularly for studying resistant strains.
    Fórmula:C18H15ClFN5O
    Cor e Forma:Solid
    Peso molecular:371.09492

    Ref: TM-T207323

  • Phen-DC3 Trifluoromethanesulfonate
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    Phen-DC3 Trifluoromethanesulfonate

    CAS:
    Phen-DC3 Trifluoromethanesulfonate targets G-quadruplexes and inhibits FANCJ/DinG helicases; IC50s: 65±6/50±10 nM.
    Fórmula:C36H26F6N6O8S2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:848.75

    Ref: TM-T13817L

  • Logotipo do CymitQuimica
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    wrwycr-NH2 TFA

    wrwycr-NH2 (TFA) is a peptide that exhibits cytotoxic properties against various cancer cells, inducing DNA damage and cell cycle arrest without causing endoplasmic reticulum stress. It possesses antitumor activity, and its efficacy is enhanced when used in combination with DNA-damaging agents.
    Cor e Forma:Odour Solid

    Ref: TM-TP3227

  • Risuteganib
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    Risuteganib

    CAS:
    <p>Risuteganib is a synthetic RGD (arginyl-glycyl-aspartic acid)-class peptide that regulates the functions of multiple integrin isoforms.</p>
    Fórmula:C22H39N9O11S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:637.66

    Ref: TM-TP1489

  • 4-Amino-1-(2-C-methyl-β-D-ribofuranosyl)-1H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile
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    4-Amino-1-(2-C-methyl-β-D-ribofuranosyl)-1H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile

    CAS:
    4-Amino-5-cyano-1-(2-β-C-methyl-β-D-ribofuranosyl)-7H-pyrrolo[2.3-d]pyrimidine, a purine nucleoside analogue, exhibits widespread antitumor efficacy,
    Fórmula:C13H15N5O4
    Cor e Forma:Solid
    Peso molecular:305.29

    Ref: TM-T75076

  • Logotipo do CymitQuimica
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    Biotin-PEG8-Vidarabine

    Biotin-PEG8-Vidarabine is an antiviral PEG linker targeting herpes and varicella zoster with adenosine analog Vidarabine.
    Fórmula:C36H60N8O13S
    Cor e Forma:Solid
    Peso molecular:844.97

    Ref: TM-T74384

  • Nogalamycin
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    Nogalamycin

    CAS:
    Nogalamycin is an anthracycline antibiotic with antitumor properties produced by soil bacteria Streptomyces nogalater.
    Fórmula:C39H49NO16
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:787.812

    Ref: TM-T28185

  • 5'-O-DMT-2'-O-TBDMS-Ac-rC
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    5'-O-DMT-2'-O-TBDMS-Ac-rC

    CAS:
    5’-O-DMT-2’-O-TBDMS-Ac-rC is a modified nucleoside and can be used to synthesize DNA or RNA.
    Fórmula:C38H47N3O8Si
    Cor e Forma:Solid
    Peso molecular:701.892

    Ref: TM-T37132

  • Rachelmycin
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    Rachelmycin

    CAS:
    Rachelmycin, a potent antibiotic and antitumor agent from Streptomyces zelensis, binds to DNA's minor groove.
    Fórmula:C37H33N7O8
    Cor e Forma:Solid
    Peso molecular:703.712

    Ref: TM-T40810

  • CDK8-IN-12
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    CDK8-IN-12

    CAS:
    CDK8-IN-12: selective CDK8 inhibitor (Ki 14 nM), oral anticancer, blocks GSK-3α/β, PCK-θ, halts MV4-11 cell growth.
    Fórmula:C21H20ClN3O2
    Pureza:98.55% - 99.22%
    Cor e Forma:Soild
    Peso molecular:381.86

    Ref: TM-T72048

  • Fibronectin CS1 Peptide
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    Fibronectin CS1 Peptide

    CAS:
    Fibronectin CS1 peptide inhibits tumor metastasis, lacking RGD domain; may aid cancer therapy.
    Fórmula:C38H64N8O15
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:872.96

    Ref: TM-TP1526

  • Logotipo do CymitQuimica
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    N6-Methyl-2'-O-(2-methoxyethyl) adenosine

    N6-Methyl-2’-O-(2-methoxyethyl) adenosine, a purine nucleoside analog, exhibits broad antitumor activity, particularly against indolent lymphoid malignancies.
    Fórmula:C14H21N5O5
    Cor e Forma:Solid
    Peso molecular:339.35

    Ref: TM-T75062

  • Gantofiban
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    Gantofiban

    CAS:
    Gantofiban is a glycoprotein IIb/IIIa (GP IIb/IIIa) antagonist used in the treatment of cardiovascular disease and may be used to study thrombosis.
    Fórmula:C21H29N5O6
    Pureza:99.57%
    Cor e Forma:Solid
    Peso molecular:447.48

    Ref: TM-T68078

  • Logotipo do CymitQuimica
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    DHFR-IN-11

    DHFR-IN-11 (compound 6b) is a DHFR inhibitor with demonstrated inhibitory efficacy against the M.
    Cor e Forma:Odour Solid

    Ref: TM-T82570

  • Fibrinogen Binding Inhibitor Peptide
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    Fibrinogen Binding Inhibitor Peptide

    CAS:
    Synthetic dodecapeptide mimics human fibrinogen g-chain, inhibits platelet receptor (residues 400-411).
    Fórmula:C50H80N18O16
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:1189.28

    Ref: TM-TP1778

  • Cotylenin A
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    Cotylenin A

    CAS:
    Cotylenin A is a phenanthraquinone compound that synergistically works with vitamin K2 to induce monocyte differentiation and growth arrest. It also inhibits c-Myc expression while inducing cyclin G2 expression in human leukemia HL-60 cells. Cotylenin A is applicable in acute myeloid leukemia research.
    Fórmula:C33H50O11
    Cor e Forma:Solid
    Peso molecular:622.744

    Ref: TM-TN8969

  • MYC-IN-2
    Targetmol
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    MYC-IN-2

    CAS:
    MYC-IN-2 is a protein-protein inhibitor targeting the MYC protein, designed for use in cancer research.
    Fórmula:C25H17N3O2S
    Cor e Forma:Solid
    Peso molecular:423.49

    Ref: TM-T39751

  • K34c hydrochloride
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    K34c hydrochloride

    CAS:
    <p>K34c hydrochloride is an alpha5β1 integrin antagonist for glioblastoma study.</p>
    Fórmula:C26H30ClN3O4
    Pureza:99.76% - 99.89%
    Cor e Forma:Soild
    Peso molecular:483.99

    Ref: TM-T41151L