Dano de DNA/Reparo de DNA
Os inibidores de dano/ reparo do DNA são compostos que interferem nos processos envolvidos na detecção e reparo de danos ao DNA. Esses inibidores são fundamentais para estudar os mecanismos de estabilidade genômica, mutagênese e resposta ao dano ao DNA. Eles também são importantes na pesquisa do câncer, pois muitos tumores dependem de vias específicas de reparo de DNA para sobreviver. Ao inibir essas vias, os inibidores de dano/reparo de DNA podem aumentar a eficácia da quimioterapia e da radioterapia. Na CymitQuimica, oferecemos uma ampla gama de inibidores de alta qualidade de dano/reparo de DNA para apoiar sua pesquisa em biologia molecular, oncologia e farmacologia.
Subcategorias de "Dano de DNA/Reparo de DNA"
- ATM/ATR(71 produtos)
- Alquilação de DNA(11 produtos)
- DNA Metiltransferase(422 produtos)
- DNA girase(11 produtos)
- DNA-PK(51 produtos)
- MTH1(1 produtos)
- Nucleosídeo Antimetabólito/Análogo(1.388 produtos)
- Transcriptase reversa(43 produtos)
- Sirtuína(88 produtos)
- Telomerase(33 produtos)
- Topoisomerase(136 produtos)
Exibir 3 mais subcategorias
Foram encontrados 958 produtos de "Dano de DNA/Reparo de DNA"
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Ifosfamide
CAS:<p>Ifosfamide (NSC-109724), a prodrug, is a cyclophosphamide analog with antineoplastic action by DNA alkylation and crosslinking.</p>Fórmula:C7H15Cl2N2O2PPureza:99.86% - ≥95%Cor e Forma:SolidPeso molecular:261.09GED-0507-34 Levo
CAS:<p>GED-0507-34 Levo,(S)-3-(4-Aminophenyl)-2-methoxypropanoic acid,an orally available PPARγ modulator for amelioration of inflammation-driven intestinal fibrosis.</p>Fórmula:C10H13NO3Pureza:98.19%Cor e Forma:SolidPeso molecular:195.22Acyclovir
CAS:<p>Acyclovir (Aciclovir) is a synthetic analog of the purine nucleoside, guanosine, with potent antiviral activity against herpes simplex viruses type 1 and 2,</p>Fórmula:C8H11N5O3Pureza:99.77% - >99.99%Cor e Forma:Crystals From Methanol SolidPeso molecular:225.2Norfloxacin
CAS:<p>Norfloxacin (MK-0366)(Norxacin) is a broad-spectrum antibiotic that is active against both Gram-positive and Gram-negative bacteria.</p>Fórmula:C16H18FN3O3Pureza:98.54% - 99.83%Cor e Forma:White To Light-Yellow Crystalline Powder SolidPeso molecular:319.33Cisplatin
CAS:<p>Cisplatin (CDDP) is a DNA cross-linking agent.</p>Fórmula:Cl2H6N2PtPureza:97.13% - 99.63%Cor e Forma:Orange-Yellow To Deep Yellow Solid Or PowderPeso molecular:300.04Moxifloxacin hydrochloride
CAS:<p>Moxifloxacin hydrochloride (BAY12-8039 HCl) is a fourth generation fluoroquinolone with expanded activity against gram-positive bacteria and atypical pathogens.</p>Fórmula:C21H25ClFN3O4Pureza:99.91% - >99.99%Cor e Forma:SolidPeso molecular:437.89Cetaben
CAS:<p>Cetaben, a non-fibrotic drug, lowers cholesterol and triglycerides without PPARα activation.</p>Fórmula:C23H39NO2Pureza:99.59%Cor e Forma:SolidPeso molecular:361.56Nalidixic acid sodium salt
CAS:<p>Nalidixic acid sodium salt (Baktogram) is an antimicrobial agent with a limited bacteriocidal spectrum.</p>Fórmula:C12H11N2NaO3Pureza:99.72% - 99.95%Cor e Forma:White To Off-White PowderPeso molecular:254.22Pefloxacin Mesylate
CAS:<p>Pefloxacin Mesylate (Pefloxacinium mesylate) is a synthetic broad-spectrum fluoroquinolone antibacterial agent active against most gram-negative and gram-</p>Fórmula:C18H24FN3O6SPureza:99.86%Cor e Forma:SolidPeso molecular:429.46Enoxacin
CAS:<p>Enoxacin (NSC-629661) is a broad-spectrum 6-fluoronaphthyridinone antibacterial agent (fluoroquinolones) structurally related to nalidixic acid.</p>Fórmula:C15H17FN4O3Pureza:98.68% - 99.89%Cor e Forma:Off-White To Yellow CrystalsPeso molecular:320.32NSC 31150
CAS:<p>Indomethacin sodium hydrate (Indometacin sodium hydrate) is a COX1/2 inhibitor that induces migraine headaches and may be used in studies of rheumatoid joints.</p>Fórmula:C10H5Cl2NO2SPureza:98.07%Cor e Forma:SolidPeso molecular:274.12Dithranol
CAS:<p>Dithranol (cignoline) is an anthracene derivative that disrupts MITOCHONDRIA function and structure and is used for the treatment of DERMATOSES, especially</p>Fórmula:C14H10O3Pureza:93.49% - 99.33%Cor e Forma:Physical Description Lemon Yellow Leaflets Or Plates Or An Orange Powder MeltingPeso molecular:226.23Procarbazine hydrochloride
CAS:<p>Procarbazine hydrochloride (NSC-77213 HCl) is the hydrochloride salt of a methylhydrazine derivative with antineoplastic and mutagenic activities.</p>Fórmula:C12H19N3O·HClPureza:96.99% - ≥98%Cor e Forma:(Ntp 1992)Peso molecular:257.76Zidovudine
CAS:<p>Zidovudine, a synthetic dideoxynucleoside, blocks DNA replication by inhibiting DNA polymerase after activation.</p>Fórmula:C10H13N5O4Pureza:99.84% - 99.91%Cor e Forma:White To Off-White CrystalsPeso molecular:267.24Carboplatin
CAS:<p>Carboplatin (JM-8) is a cisplatin derivative, a DNA synthesis inhibitor.</p>Fórmula:C6H12N2O4PtPureza:98% - 99.72%Cor e Forma:White Crystalline PowderPeso molecular:371.25FEN1-IN-1
CAS:<p>FEN1-IN-1 (LNT-1), a FEN1 active site inhibitor, partly works by coordinating Mg2+ ions.</p>Fórmula:C15H12N2O5SPureza:99.65% - 99.80%Cor e Forma:SolidPeso molecular:332.33Lomefloxacin
CAS:<p>Lomefloxacin (SC47111A) is a synthetic broad-spectrum fluoroquinolone with antibacterial activity.</p>Fórmula:C17H19F2N3O3Pureza:98.59%Cor e Forma:Off-White To Yellow CrystalsPeso molecular:351.35LY518674
CAS:<p>LY518674 (LY-674) decreases triglycerides and increases HDL-C and is used for the treatment of atherosclerosis.</p>Fórmula:C23H27N3O4Pureza:98.87%Cor e Forma:SolidPeso molecular:409.48Abacavir
CAS:<p>Abacavir (Ziagen) is a nucleoside reverse transcriptase inhibitor analog of guanosine.</p>Fórmula:C14H18N6OPureza:99.36% - 99.81%Cor e Forma:White PowderPeso molecular:286.33MC3482
CAS:<p>MC3482 is a specific inhibitor of sirtuin5 (SIRT5).</p>Fórmula:C33H38N4O8Pureza:98% - 99.90%Cor e Forma:SoildPeso molecular:618.68Decitabine
CAS:<p>Decitabine (Deoxycytidine) is a deoxycytidine analog, a DNA methyltransferase inhibitor with oral activity.</p>Fórmula:C8H12N4O4Pureza:98.06% - 99.87%Cor e Forma:Physical Description Fine White Crystalline Powder Used As A DrugPeso molecular:228.21Levofloxacin hydrate
CAS:<p>Levofloxacin hydrate (Cravit hydrate) is a third-generation fluoroquinolone antibiotic and optically active L-isomer of ofloxacin with antibacterial activity.</p>Fórmula:C18H20FN3O4H2OPureza:98.26%Cor e Forma:Pale Yellow SolidPeso molecular:370.38Ledoxantrone trihydrochloride
CAS:<p>Ledoxantrone trihydrochloride is a Top II inhibitor with anticancer activity and is used in the study of digestive disorders and urologic disorders.</p>Fórmula:C21H30Cl3N5OSPureza:98.13%Cor e Forma:SoildPeso molecular:506.92YPX-C-05
CAS:<p>YPX-C-05, an isohydroxamic acid derivative, is an HDAC inhibitor with vasodilatory and antihypertensive activity.CAS 번호134608-84-5</p>Fórmula:C21H19N3O4Pureza:98.09%Cor e Forma:SoildPeso molecular:377.39Telomerase-IN-2
CAS:<p>Telomerase-IN-2 (Telomerase inhibitor 2) shows potent inhibitory activity against telomerase by decreasing the expression of dyskerin (IC50: 0.89 µM).</p>Fórmula:C34H39N3O9Pureza:99.32%Cor e Forma:SolidPeso molecular:633.69Methotrexate
CAS:<p>Methotrexate (WR19039) is a folate analog, an inhibitor of the dihydrofolate reductase DHFR.</p>Fórmula:C20H22N8O5Pureza:96.84% - 99.91%Cor e Forma:Orange-Brown Crystalline Powder Chemotherapy Drug That Interferes With Dna And Rna SynthesisPeso molecular:454.44STL127705
CAS:<p>STL127705 inhibits Ku 70/80 protein & DNA-PKCS kinase, IC50s: 3.5 μM & 2.5 μM.</p>Fórmula:C22H20FN5O4Pureza:99.53% - 99.81%Cor e Forma:SolidPeso molecular:437.42Teniposide
CAS:<p>Teniposide (VM26), a semisynthetic derivative of podophyllotoxin with antitumor activity, inhibits DNA synthesis by forming a complex with topoisomerase II and</p>Fórmula:C32H32O13SPureza:97.7% - 99.45%Cor e Forma:White Or Off-White Crystalline PowderPeso molecular:656.65CG347B
CAS:<p>CG347B is a selective inhibitor of HDAC6.</p>Fórmula:C16H17N3O2Pureza:98.34%Cor e Forma:SolidPeso molecular:283.33Ramatroban
CAS:<p>Ramatroban (BAY u3405) (BAY u3405) is a thromboxane A(2) (TxA(2)) antagonist marketed for allergic rhinitis.</p>Fórmula:C21H21FN2O4SPureza:98.75% - >99.99%Cor e Forma:Crystalline SolidPeso molecular:416.47Elimusertib hydrochloride(1876467-74-1 free base)
<p>Elimusertib hydrochloride(1876467-74-1 free base) (BAY-1895344 hydrochloride) is a effective, orally available and selective ATR inhibitor with anti-tumor</p>Fórmula:C20H22ClN7OPureza:98.8% - 99.03%Cor e Forma:SolidPeso molecular:411.89DC-05
CAS:<p>DC-05 is an inhibitor of DNA methyltransferase 1 (DNMT1) (IC50 and a Kd: 10.3 μM and 1.09 μM, respectively).</p>Fórmula:C25H25N3OPureza:98.95%Cor e Forma:SolidPeso molecular:383.49Ceramides Mixture
CAS:<p>Ceramides Mixture: endogenous, regulates cell cycle, growth, and telomerase activity, with hydroxy/non-hydroxy fatty acids.</p>Fórmula:C36H71NO4Pureza:98%Cor e Forma:SolidPeso molecular:581.967Abexinostat
CAS:<p>Abexinostat (PCI-24781) is a pan-HDAC inhibitor, strongest on HDAC1; less so on HDACs 2, 3, 6, 10. Very select for HDAC8. In Phase 1/2 trials.</p>Fórmula:C21H23N3O5Pureza:98.19% - 98.43%Cor e Forma:SolidPeso molecular:397.42Nalidixic acid
CAS:<p>Nalidixic acid (NSC-82174), a synthetic antimicrobial, targets bacterial DNA gyrase A, with a narrow bactericidal range.</p>Fórmula:C12H12N2O3Pureza:99.9% - 99.95%Cor e Forma:Pale Buff Crystalline Powder Physical Description Cream-Colored Powder (Ntp 1992)Peso molecular:232.24AES-135
CAS:<p>AES-135 is a potent HDAC inhibitor, inhibits HDAC3, HDAC6, HDAC11 (IC50s: 654, 190, and 636 nM) with anti-tumor activity.</p>Fórmula:C33H29F6N3O5SPureza:97.72%Cor e Forma:SolidPeso molecular:693.661-Naphthohydroxamic acid
CAS:<p>1-Naphthohydroxamic acid (Compound 2) is a potent and selective HDAC8 inhibitor with an IC50 of 14 μM, and it is more selectively for HDAC8 than class I HDAC1</p>Fórmula:C11H9NO2Pureza:99.19%Cor e Forma:SolidPeso molecular:187.19Adenine
CAS:<p>Adenine: a purine nucleobase vital for ATP, NAD, FAD production, and DNA/RNA synthesis.</p>Fórmula:C5H5N5Pureza:99.39% - 99.95%Cor e Forma:SolidPeso molecular:135.13SIRT-IN-2
CAS:<p>SIRT-IN-2 is a potent SIRT1/2/3 inhibitor(IC50s of 4, 1, 7 μM, respectively).</p>Fórmula:C15H21N5O3S2Pureza:98.26%Cor e Forma:SolidPeso molecular:383.49NTP42
CAS:<p>NTP42 is an antagonist of thromboxane A2 (TXA2) receptor(IC50 of 3.278 nM)</p>Fórmula:C25H23F2N3O5SPureza:97.55%Cor e Forma:SolidPeso molecular:515.53Thio-TEPA
CAS:<p>Thio-TEPA (Tiofosyl) is a polyfunctional, organophosphorus alkylating agent with antineoplastic activity.</p>Fórmula:C6H12N3PSPureza:98.45% - 99.07%Cor e Forma:White Crystals Or PowderPeso molecular:189.22Gimeracil
CAS:<p>Gimeracil (Gimestat) is a competitive, reversible inhibitor of dihydropyrimidine dehydrogenase.</p>Fórmula:C5H4ClNO2Pureza:99.80%Cor e Forma:SolidPeso molecular:145.54Bendamustine hydrochloride
CAS:<p>Bendamustine hydrochloride (EP-3101) (IC50 of 50 μM) is an alkylating agent associated with DNA damage.</p>Fórmula:C16H21Cl2N3O2·HClPureza:97.71%Cor e Forma:SolidPeso molecular:394.72Lurtotecan
CAS:<p>Lurtotecan (GI147211) is a semisynthetic Camptothecin analog. Lurtotecan is a topoisomerase I inhibitor with anticancer effects.</p>Fórmula:C28H30N4O6Pureza:99.18%Cor e Forma:SoildPeso molecular:518.56HDAC-IN-40
CAS:<p>HDAC-IN-40 is a potent alkoxyamide-based HDAC inhibitor with Ki of 60 nM and 30 nM for HDAC2 and HDAC6, respectively. HDAC-IN-40 had antitumor effects</p>Fórmula:C15H22N2O6Pureza:99.04%Cor e Forma:SoildPeso molecular:326.35Ganciclovir
CAS:<p>Ganciclovir (2'-Nor-2'-deoxyguanosine) is an ACYCLOVIR analog that is a potent inhibitor of the Herpesvirus family including cytomegalovirus.</p>Fórmula:C9H13N5O4Pureza:99.55% - 99.58%Cor e Forma:White PowderPeso molecular:255.23XR-11576 HCl
<p>XR-11576 HCl is a novel orally active dual topoisomerase I and II inhibitor with antitumor activity.</p>Fórmula:C23H25ClN4O2Pureza:98.52%Cor e Forma:SoildPeso molecular:424.92Dihydro-5-azacytidine FA
<p>Dihydro-5-azacytidine FA (DHAC) is a pyrimidine analog that has antitumor activity, inhibits cell growth, inhibits DNA methylation, and may be used in the study of malignant mesothelioma.</p>Fórmula:C9H16N4O7Pureza:>99.99%Cor e Forma:SolidPeso molecular:292.25DRF-1042 HCl
<p>DRF-1042 HCl is an orally active camptothecin analog with antitumor activity, inhibits DNA topoisomerase I, and is used in the study of refractory solid tumors.</p>Fórmula:C22H21ClN2O6Pureza:97.93%Cor e Forma:SolidPeso molecular:444.87Foscarnet sodium
CAS:<p>Foscarnet sodium (Phosphonoformate) is an antiviral agent used in the treatment of cytomegalovirus retinitis.</p>Fórmula:CNa3O5PPureza:98.52%Cor e Forma:White Or Almost White Crystalline PowderPeso molecular:191.95Tallimustine HCl
CAS:<p>Tallimustine HCl, an AT-specific alkylating agent, treats leukemia in immunodeficiency mouse models.</p>Fórmula:C32H39Cl3N10O4Pureza:98.52%Cor e Forma:SoildPeso molecular:734.08Candesartan
CAS:<p>Candesartan (CV 11974) is an angiotensin II receptor blocker used widely in the therapy of hypertension and heart failure.</p>Fórmula:C24H20N6O3Pureza:98.3% - 99.55%Cor e Forma:Colorless Solid CrystallinePeso molecular:440.47Oxaquin TEA
<p>Oxaquin TEA (MCB-3837 TEA), a precursor compound to MCB3681, is a DNA topoisomerase inhibitor that can be used to study Clostridium difficile infections and</p>Fórmula:C37H48F2N5O11PPureza:99.79%Cor e Forma:SolidPeso molecular:807.77MSDC-0602K
CAS:<p>MSDC-0602K, a Ps-TZD, targets PPARγ (IC50: 18.25 μM) and MPC, may help study fatty liver, lipid imbalance, inflammation, and insulin issues.</p>Fórmula:C19H16KNO5SPureza:99.42%Cor e Forma:SolidPeso molecular:409.5Flumequine
CAS:<p>Flumequine (R-802) is a broad-spectrum antibiotic targeting DNA gyrase and topoisomerase IV in Gram-positive and Gram-negative bacteria.</p>Fórmula:C14H12FNO3Pureza:98.92% - 99.4%Cor e Forma:White Crystalline Powder SolidPeso molecular:261.25RBN-2397
CAS:<p>RBN-2397 is a potent, selective and orally active accross species NAD+ competitive PARP7 inhibitor with IC50 less than 3 nM.</p>Fórmula:C20H23F6N7O3Pureza:98.48% - 99.8%Cor e Forma:SolidPeso molecular:523.43Ciprofloxacin
CAS:<p>Ciprofloxacin (Bay-09867) mainly targets bacterial DNA Gyrase (IC50=0.22-0.31 µM) and topoisomerase IV (IC50=0.3-1.9 µM). antibiotic. High-Quality, Low-Cost!</p>Fórmula:C17H18FN3O3Pureza:98.77% - 99.91%Cor e Forma:White PowderPeso molecular:331.34Balofloxacin
CAS:<p>Balofloxacin, a quinolone antibiotic, can inhibit the synthesis of bacterial DNA by interfering with the DNA gyrase.</p>Fórmula:C20H24FN3O4Pureza:99.62% - 99.98%Cor e Forma:Crystalline SolidPeso molecular:389.42Niraparib (R-enantiomer)
CAS:<p>Niraparib R-enantiomer (MK 4827 R-enantiomer) is an inhibitor of PARP1(IC50 of 2.4 nM).</p>Fórmula:C19H20N4OPureza:99.83%Cor e Forma:SolidPeso molecular:320.39Hydroxychloroquine sulfate
CAS:<p>Hydroxychloroquine sulfate (Acidum iopanoicum) inhibits plasmodial heme polymerase.</p>Fórmula:C18H26ClN3O·H2SO4Pureza:98.92% - 99.88%Cor e Forma:Odorless SolidPeso molecular:433.95Enoxacin hydrate
CAS:<p>Enoxacin hydrate (AT-2266 hydrate) is a broad-spectrum 6-fluoronaphthyridinone antibacterial agent.</p>Fórmula:C15H17FN4O3H2OPureza:99.50%Cor e Forma:SolidPeso molecular:347.34Gemfibrozil
CAS:<p>Gemfibrozil, a fibric acid derivative, stimulates PPARalpha, boosts fatty acid oxidation, LPL, lowers VLDL-C, apoC-III, and raises HDL-C.</p>Fórmula:C15H22O3Pureza:99.53% - 99.88%Cor e Forma:Crystals From Hexane SolidPeso molecular:250.33Altretamine
CAS:<p>Altretamine (ENT-50852) is an alkylating agent with antineoplastic activity.</p>Fórmula:C9H18N6Pureza:99.54%Cor e Forma:Less Crystalline Solid Insoluble In Water (Ntp 1992) Physical Description Colorless Crystalline Solid Insoluble In Water (Ntp 1992)Peso molecular:210.28Chlorambucil
CAS:<p>Chlorambucil (CB-1348) is an orally-active antineoplastic aromatic nitrogen mustard.</p>Fórmula:C14H19Cl2NO2Pureza:97.37% - 98.45%Cor e Forma:Off-White Slightly Granular Powder Melting Point 65-69°CPeso molecular:304.21Ciprofloxacin monohydrochloride
CAS:<p>Ciprofloxacin monohydrochloride (Bay-09867 hydrochloride) is a broad-spectrum antimicrobial carboxyfluoroquinoline.</p>Fórmula:C17H18FN3O3·HClPureza:99.5% - >99.99%Cor e Forma:White Or Light Yellow Crystalline PowderPeso molecular:367.80G150
CAS:<p>G150 suppresses DSDNA-induced interferon; IC50: 10.2 nM. It's a potent, selective H-CGAS inhibitor.</p>Fórmula:C18H16Cl2N4O2Pureza:97.75%Cor e Forma:SolidPeso molecular:391.25BRD 4354
CAS:<p>BRD 4354 is an inhibitor of HDAC5 and HDAC9. For HDAC5 and HDAC9, the IC50s values are 0.85 and 1.88 μM, respectively.</p>Fórmula:C21H23ClN4OPureza:99.86%Cor e Forma:SolidPeso molecular:382.89Levetiracetam
CAS:<p>Levetiracetam (SIB-S1) is a relatively unique anticonvulsant that is typically used in combination with other antiepileptic medications for partial onset</p>Fórmula:C8H14N2O2Pureza:99.67% - 99.86%Cor e Forma:White Crystalline PowderPeso molecular:170.215-Azacytidine
CAS:<p>5-Azacytidine (Ladakamycin) is a cytidine nucleoside analog, a DNA methylation inhibitor with specificity.</p>Fórmula:C8H12N4O5Pureza:99.31% - 99.79%Cor e Forma:Crystals From Methanol Physical Description White Crystalline Powder (Ntp 1992)Peso molecular:244.2LTURM34
CAS:<p>LTURM34 is an inhibitor of DNA-PK with IC50 of 34 nM.</p>Fórmula:C24H18N2O3SPureza:99.34%Cor e Forma:SolidPeso molecular:414.48Clofibric acid
CAS:<p>Clofibric acid (Chlorofibrinic acid) is an antilipemic agent that is the biologically active metabolite of CLOFIBRATE.</p>Fórmula:C10H11ClO3Pureza:99.47% - 99.8%Cor e Forma:Pale Yellow SolidPeso molecular:214.65Sparfloxacin
CAS:<p>Sparfloxacin (CI-978) is a fluoroquinolone antibiotic that inhibits bacterial DNA gyrase, thereby inhibiting DNA replication and transcription.</p>Fórmula:C19H22F2N4O3Pureza:99.67% - >99.99%Cor e Forma:Light Yellow PowderPeso molecular:392.40Fleroxacin
CAS:<p>Fleroxacin (RO 23-6240) is a broad-spectrum antimicrobial fluoroquinolone. It strongly inhibits the DNA-supercoiling activity of DNA gyrase.</p>Fórmula:C17H18F3N3O3Pureza:99.58% - 99.79%Cor e Forma:White Needle-Like CrystalsPeso molecular:369.34Mifobate
CAS:Mifobate (SR-202) 是一种有效且特异性的 PPARγ拮抗剂，可选择性抑制噻唑烷二酮 (TZD) 诱导的 PPARγ 转录活性，IC50为140 μM，具有抗肥胖和抗糖尿病作用。Fórmula:C11H17ClO7P2Pureza:99.12%Cor e Forma:SolidPeso molecular:358.65Topixantrone 2HCl
CAS:<p>Topixantrone 2HCl is a DNA topoisomerase inhibitor with antitumor activity for the study of gastric and prostate cancer.</p>Fórmula:C21H28Cl2N6O2Pureza:99.96% - >99.99%Cor e Forma:SoildPeso molecular:467.39Ofloxacin
CAS:<p>Ofloxacin (Oxaldin) is a fluoroquinolone antibacterial antibiotic.</p>Fórmula:C18H20FN3O4Pureza:99.33% - 99.87%Cor e Forma:Off-White SolidPeso molecular:361.37Gatifloxacin
CAS:<p>Gatifloxacin (CG5501), a fourth-gen fluoroquinolone antibiotic, blocks bacterial DNA gyrase and topoisomerase IV.</p>Fórmula:C19H22FN3O4Pureza:99.50% - 99.85%Cor e Forma:White PowderPeso molecular:375.39TRF1-TIN2 interaction-IN-1
<p>TRF1-TIN2 interaction-IN-1 (Compound 40) is an inhibitor of the TRF1-TIN2 interaction. It binds to the TRFH domain of TRF1 (KD= 29 μM) and competitively inhibits the binding of the TIN2 peptide (IC50= 67 μM). By occupying a hotspot at the TRF1-TIN2 interface, TRF1-TIN2 interaction-IN-1 disrupts the interaction between TRF1 and TIN2. This compound can remove TRF1 from the shelterin complex, making it useful for research on shelterin-related cancers.</p>Fórmula:C19H18O6SCor e Forma:SolidPeso molecular:374.41(R)-VX-984
CAS:<p>(R)-VX-984 ((R)-M9831) is the (R)-enantiomer of VX-984. VX-984 is a potent inhibitor of DNA-PK.</p>Fórmula:C23H21D2N7OPureza:98%Cor e Forma:SolidPeso molecular:415.49PDPH Crosslinker
CAS:<p>PDPH crosslinker(SPDP Hydrazide) is a lytic heterobisfunctional protein crosslinker.</p>Fórmula:C8H11N3OS2Cor e Forma:SolidPeso molecular:229.32DB1255 2TFA
<p>DB1255 2TFA is an ERG/DNA binding inhibitor with an unusual and potent monomer binding pattern at the minor groove site for the study of genetic disorders.</p>Fórmula:C26H20F6N4O4S2Pureza:98.32%Cor e Forma:SolidPeso molecular:630.58CAY10599
CAS:<p>CAY10599 has a wide range of applications in life science related research.</p>Fórmula:C38H41NO5Cor e Forma:SolidPeso molecular:591.748NHC-triphosphate tetrasodium
<p>NHC-triphosphate tetrasodium, a metabolite of β-d-N4-Hydroxycytidine, acts as a viral polymerase substrate affecting HCV RNA replication.</p>Fórmula:C9H12N3Na4O15P3Cor e Forma:SolidPeso molecular:587.08Amorfrutin B
CAS:<p>Amorfrutin B is a useful organic compound for research related to life sciences. The catalog number is T124211 and the CAS number is 78916-42-4.</p>Fórmula:C26H32O4Cor e Forma:SolidPeso molecular:408.538Tibesaikosaponin V
CAS:<p>TKV, a triterpene diglycoside from Bupleurum chinense, curbs lipid build-up and fat content in adipocytes without harm and hinders fat cell differentiation.</p>Fórmula:C42H68O15Cor e Forma:SolidPeso molecular:812.98GW 1929 hydrochloride
CAS:<p>Oral PPARγ agonist with pEC50 of 8.05; low affinity for PPARα, PPARδ. Reduces blood glucose, fatty acids, triglycerides in vivo.</p>Fórmula:C30H30ClN3O4Cor e Forma:SolidPeso molecular:532.04SMPB Crosslinker
CAS:<p>SMPB crosslinker reacts with sulfhydryl/amino groups, has a longer chain than MBS, and a non-cleavable spacer arm.</p>Fórmula:C18H16N2O6Pureza:98%Cor e Forma:SolidPeso molecular:356.33Anti-obesity agent 1
<p>Compound 4 (Anti-obesity agent 1) demonstrates potential for enhanced lipolysis, highlighting its anti-obesity characteristics.</p>Fórmula:C21H22N2O6Cor e Forma:SolidPeso molecular:398.409ACT-387042
CAS:<p>ACT-387042 is a Bacterial Topoisomerase Inhibitor, it has broad-spectrum activity against Gram-positive and Gram-negative bacteria.</p>Fórmula:C23H26FN5O4SCor e Forma:SolidPeso molecular:487.55CUDA disodium
<p>CUDA disodium is an effective, soluble epoxide hydrolase (sEH) inhibitor, with IC50 values of 11.1 nM for murine sEH and 112 nM for human sEH. It selectively enhances the activity of peroxisome proliferator-activated receptor PPARalpha. CUDA disodium may be valuable for cardiovascular disease research.</p>Cor e Forma:Odour SolidGemfibrozil 1-O-β-glucuronide
CAS:<p>Gemfibrozil 1-O-β-Glucuronide, a metabolite of Gemfibrozil , is a potent and competitive P450 (CYP) isoform CYP2C8 inhibitor with an IC50 of 4.07 μM.</p>Fórmula:C21H30O9Pureza:98%Cor e Forma:SolidPeso molecular:426.46DNA Damage & Repair Compound Library
<p>A unique collection of xnum DNA Damage &amp; Repair related compounds for high throughput screening (HTS) and high content screening (HCS);</p>Cor e Forma:Odour SolidWAY-323061
CAS:<p>WAY-323061 is a SIRT2 inhibitor.</p>Fórmula:C25H21N5O2SPureza:99.33%Cor e Forma:SolidPeso molecular:455.53NHC-diphosphate triammonium
<p>NHC-triphosphate triammonium is a phosphorylated metabolite of NHC, incorporated into HCV RNA by viral polymerase.</p>Cor e Forma:SolidTAK1 inhibitor
CAS:<p>TAK1 inhibitor is an inhibitor, which can inhibit MCF-7, A549, DU-145 and MDA MB-231, with IC50 of 0.021, 0.14, 0.064 and 0.19, respectively.</p>Fórmula:C22H19ClN6O2SPureza:98%Cor e Forma:SoildPeso molecular:466.94MS9024
<p>MS9024 is a degrader of DNA methyltransferase 1 (DNMT1), facilitating its degradation in HCT116 cells via the ubiquitin-proteasome pathway, with a DC50 of 35 nM (DC50 values are 254 nM in MDA-MB-468 and 101 nM in H1299). Additionally, MS9024 inhibits DNMT1 with an IC50 of 0.43 μM.</p>Cor e Forma:Odour SolidGSK3735967
CAS:<p>GSK3735967: DNMT1 inhibitor, IC50 40 nM, dicyanopyridine core, binds hemimethylated CpG, interacts with H4K20me3.</p>Fórmula:C25H31N7OSCor e Forma:SolidPeso molecular:477.62Ciprofibrate impurity A
CAS:<p>Ciprofibrate impurity A is an impurity of Ciprofibrate. Ciprofibrate is a PPARα agonist[1].</p>Fórmula:C12H14O3Cor e Forma:SolidPeso molecular:206.241Murrayanol
<p>Murrayanol is a useful organic compound for research related to life sciences and the catalog number is T125851.</p>Fórmula:C24H29NO2Cor e Forma:SolidPeso molecular:363.501Elomotecan
CAS:<p>Elomotecan (BN 80927 free base) is a potent inhibitor of topoisomerases I and II.Cost-effective and quality-assured.</p>Fórmula:C29H32ClN3O4Cor e Forma:SolidPeso molecular:522.04
