Dano de DNA/Reparo de DNA
Os inibidores de dano/ reparo do DNA são compostos que interferem nos processos envolvidos na detecção e reparo de danos ao DNA. Esses inibidores são fundamentais para estudar os mecanismos de estabilidade genômica, mutagênese e resposta ao dano ao DNA. Eles também são importantes na pesquisa do câncer, pois muitos tumores dependem de vias específicas de reparo de DNA para sobreviver. Ao inibir essas vias, os inibidores de dano/reparo de DNA podem aumentar a eficácia da quimioterapia e da radioterapia. Na CymitQuimica, oferecemos uma ampla gama de inibidores de alta qualidade de dano/reparo de DNA para apoiar sua pesquisa em biologia molecular, oncologia e farmacologia.
Subcategorias de "Dano de DNA/Reparo de DNA"
- ATM/ATR(71 produtos)
- Alquilação de DNA(11 produtos)
- DNA Metiltransferase(422 produtos)
- DNA girase(11 produtos)
- DNA-PK(51 produtos)
- MTH1(1 produtos)
- Nucleosídeo Antimetabólito/Análogo(1.388 produtos)
- Transcriptase reversa(43 produtos)
- Sirtuína(88 produtos)
- Telomerase(33 produtos)
- Topoisomerase(136 produtos)
Exibir 3 mais subcategorias
Foram encontrados 958 produtos de "Dano de DNA/Reparo de DNA"
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Torin 1
CAS:<p>Torin 1 is an effective inhibitor of mTORC1/2 with (IC50: 2 nM/10 nM); has 1000-fold selectivity for mTOR than PI3K.</p>Fórmula:C35H28F3N5O2Pureza:98.3% - 99.33%Cor e Forma:SolidPeso molecular:607.62Adenine hydrochloride
CAS:<p>Adenine hydrochloride (6-Aminopurine hydrochloride) is a hydrochloride salt form of adenine which is a nucleobase with a variety of roles in biochemistry.</p>Fórmula:C5H5N5·HClPureza:98.86%Cor e Forma:White To Light Yellow Crystal PowderPeso molecular:171.59ITSA-1
CAS:<p>ITSA-1 is membrane permeable and specifically suppresses TSA inhibition of HDAC (histone deacetylase), but shows no activity towards other HDAC inhibitors.</p>Fórmula:C13H7Cl2N3OPureza:99.78% - 99.89%Cor e Forma:SolidPeso molecular:292.12SirReal2
CAS:<p>SirReal2 is a potent and selective Sirt2 inhibitor with IC50 of 140 nM.</p>Fórmula:C22H20N4OS2Pureza:98.96% - 99.75%Cor e Forma:SolidPeso molecular:420.55GSK3685032
CAS:<p>GSK3685032 is a non-covalent and selective DNMT1 inhibitor(IC50 = 36 nM).</p>Fórmula:C22H24N6OSPureza:98.56% - 99.49%Cor e Forma:SolidPeso molecular:420.53NU 7026
CAS:<p>NU 7026 (DNA-PK Inhibitor II) is an effective DNA-PK inhibitor (IC50: 0.23 μM, in cell-free assays), 60-fold selective for DNA-PK than PI3K and no inhibition</p>Fórmula:C17H15NO3Pureza:99.51% - >99.99%Cor e Forma:SolidPeso molecular:281.31Hinokitiol
CAS:<p>Hinokitiol prevents UVB-caused cell death, boosts antioxidant activity, and hinders breast cancer growth.</p>Fórmula:C10H12O2Pureza:99.49% - 99.67%Cor e Forma:SolidPeso molecular:164.2Carmustine
CAS:<p>Carmustine (bis-chloroethylnitrosourea) is a cell-cycle phase nonspecific alkylating antineoplastic agent.</p>Fórmula:C5H9Cl2N3O2Pureza:98% - 99.91%Cor e Forma:Light Yellow Powder Physical Description Orange-Yellow Solid (Ntp 1992)Peso molecular:214.05VAL-083
CAS:<p>VAL-083 (Dianhydrogalactitol) is an alkylating compound that creates N7 methylation on DNA. It also has antitumor activity.</p>Fórmula:C6H10O4Pureza:97.94%Cor e Forma:SolidPeso molecular:146.14PI3K-IN-1
CAS:<p>PI3K-IN-1 (Voxtalisib Analogue) is a dual inhibitor of mTOR/PI3K, mostly for p110γ , also inhibits DNA-PK and mTOR.</p>Fórmula:C31H29N5O6SPureza:97.03% - 98%Cor e Forma:SolidPeso molecular:599.66Niraparib
CAS:<p>Niraparib (MK-4827) inhibits PARP1/PARP2 (IC50: 3.8/2.1 nM), effective on BRCA mutant cancers, 330x less effective on PARP3, V-PARP, Tank1.</p>Fórmula:C19H20N4OPureza:98% - 99.91%Cor e Forma:SolidPeso molecular:320.39FIT-039
CAS:<p>FIT-039 is a selective and ATP-competitive, orally active inhibitor of CDK9( IC50 : 5.8 μM;CDK9/cyclin T1).</p>Fórmula:C17H18FN3SPureza:98.61%Cor e Forma:SolidPeso molecular:315.41BRD7116
CAS:<p>BRD7116 competitively binds to bacterial DNA gyrase, with cell-non-autonomous anti-leukemia activity.</p>Fórmula:C28H36N2O4SPureza:99.69% - 99.91%Cor e Forma:SolidPeso molecular:496.66Adenine hemisulfate
CAS:<p>Adenine hemisulfate (Diadenine sulphate) is a sulfate salt form of adenine which is a purine derivative and a nucleobase with a variety of roles in biochemistry</p>Fórmula:(C5H5N5)·H2SO4Pureza:99.48%Cor e Forma:White To Light Yellow Crystal PowderPeso molecular:368.33BIBR 1532
CAS:<p>BIBR 1532 is an effective, specific and non-competitive telomerase inhibitor (IC50: 100 nM, in a cell-free assay).</p>Fórmula:C21H17NO3Pureza:98.49% - 98.90%Cor e Forma:SolidPeso molecular:331.364-amino-1,8-Naphthalimide
CAS:<p>4-amino-1,8-Naphthalimide (4-ANI) is a PARP inhibitor with IC50 of 180 nM</p>Fórmula:C12H8N2O2Pureza:95.13%Cor e Forma:Yellow Solid PowderPeso molecular:212.2NMS-P118
CAS:<p>NMS-P118 is a potent, selective and orally available Inhibitor of PARP-1 for cancer therapy.</p>Fórmula:C20H24F3N3O2Pureza:98.79%Cor e Forma:SolidPeso molecular:395.42CP-466722
CAS:<p>CP-466722, an effective and reversible ATM inhibitor, does not inhibit ATR and PI3K or PIKK family members in cells.</p>Fórmula:C17H15N7O2Pureza:99.1% - 99.14%Cor e Forma:SolidPeso molecular:349.35CAY10603
CAS:<p>CAY10603 (BML-281) is a potent and selective inhibitor of HDAC6.</p>Fórmula:C22H30N4O6Pureza:95.75% - 98.1%Cor e Forma:SolidPeso molecular:446.5RK-287107
CAS:<p>RK-287107 is an effective and specific inhibitor of tankyrase (IC50s: 14.3 and 10.6 nM for tankyrase-1 and tankyrase-2, respectively).</p>Fórmula:C22H26F2N4O2Pureza:99.64%Cor e Forma:SolidPeso molecular:416.46Thiacloprid
CAS:<p>Thiacloprid: insecticide targeting insect nAChRs, IC50 - Drosophila: 2.7 nM, Mouse α4β2 nAChRs: 860 nM.</p>Fórmula:C10H9ClN4SPureza:98.66% - 99.95%Cor e Forma:Yellowish Crystalline PowderPeso molecular:252.72Ciprofloxacin hydrochloride monohydrate
CAS:<p>Ciprofloxacin hydrochloride monohydrate (Bay-09867 hydrochloride monohydrate) is a fluoroquinolone antibiotic with potent antibacterial activity.</p>Fórmula:C17H21ClFN3O4Pureza:99.23% - 99.85%Cor e Forma:White Or Yellowish Crystalline PowderPeso molecular:385.82Pentamidine dihydrochloride
CAS:<p>Pentamidine dihydrochloride (MP-601205 dihydrochloride) is an aromatic diamidine agent with activity against a number of microorganisms including protozoa (</p>Fórmula:C19H26Cl2N4O2Pureza:99.80%Cor e Forma:SolidPeso molecular:413.34Silver sulfadiazine
CAS:<p>Silver sulfadiazine (Dermazin) is a sulfonamide-based topical agent with antibacterial and antifungal activity.</p>Fórmula:C10H9AgN4O2SPureza:99.04% - 99.58%Cor e Forma:SolidPeso molecular:357.14BCH001
CAS:<p>BCH001 is a specific small-molecule inhibitor of PAPD5.</p>Fórmula:C20H15F3N2O5Pureza:99.06%Cor e Forma:SolidPeso molecular:420.34NU2058
CAS:<p>NU2058 (O(6)-Cyclohexylmethylguanine) is a guanine-based CDK inhibitor, also inhibits DNA topoisomerase II ATPase activity.</p>Fórmula:C12H17N5OPureza:99.34% - 99.92%Cor e Forma:SolidPeso molecular:247.3Pentamidine isethionate
CAS:<p>Pentamidine isethionate (Pentamidine diisethionate) is a synthetic amidine derivative, Pentamidine Isethionate is an antiprotozoal and antifungal agent.</p>Fórmula:C23H36N4O10S2Pureza:98% - 99.83%Cor e Forma:Slight Butyric Odor Very Bitter Taste Ph (5% Aqueous Solution) 4 5-6 5 (Ntp 1992)Peso molecular:592.68Trifluridine/tipiracil hydrochloride mixture
CAS:<p>Trifluridine/tipiracil hydrochloride mixture (TAS-102) is a novel oral combination drug containing trifluridine (TFT) and Tipiracil hydrochloride (TTP) in a</p>Fórmula:C29H34Cl2F6N8O12Pureza:98% - 99.79%Cor e Forma:SolidPeso molecular:871.53Remodelin hydrobromide
CAS:<p>Remodelin hydrobromide (Remodelin HBR) is a novel potent and selective inhibitor of the acetyl-transferase protein NAT10.</p>Fórmula:C15H15BrN4SPureza:97.22% - 99.84%Cor e Forma:SolidPeso molecular:363.275Rucaparib Phosphate
CAS:<p>Rucaparib Phosphate (PF-01367338 phosphate) is an inhibitor of PARP that is used in clinical therapy to sensitize cancer cells to chemotherapy.</p>Fórmula:C19H18FN3O·H3PO4Pureza:99.37%Cor e Forma:SolidPeso molecular:421.36Trovafloxacin
CAS:<p>Trovafloxacin, a broad-spectrum quinolone antibiotic, exhibits potent activity against Gram-positive bacteria.</p>Fórmula:C20H15F3N4O3Pureza:99.21% - 99.27%Cor e Forma:SolidPeso molecular:416.35Dxd
CAS:<p>Dxd (OQM5SD32BQ) is a potent DNA topoisomerase I inhibitor (IC50= 0.31 μM). Dxd was used as a conjugate drug for HER2-targeted ADCs. High-Quality, Low-Cost!</p>Fórmula:C26H24FN3O6Pureza:98.21% - ≥98%Cor e Forma:SolidPeso molecular:493.48Bendamustine
CAS:<p>Bendamustine (SDX105) for the treatment of Non-Hodgkin Lymphomas and Chronic Lymphocytic Leukemia</p>Fórmula:C16H21Cl2N3O2Pureza:≥98%Cor e Forma:SolidPeso molecular:358.26Clomesone
CAS:<p>Clomesone, a synthetic drug, treats female infertility by blocking brain estrogen, inducing ovulation.</p>Fórmula:C4H9ClO5S2Pureza:99%Cor e Forma:SolidPeso molecular:236.69AZ20
CAS:<p>AZ20 is an effective and specific inhibitor of ATR kinase (IC50: 5 nM, in a cell-free assay), 8-fold selectivity over mTOR.</p>Fórmula:C21H24N4O3SPureza:98% - 99.69%Cor e Forma:SolidPeso molecular:412.51Topovale
CAS:<p>Topovale (ARC111) is a potent inhibitor of topoisomerase I.</p>Fórmula:C23H23N3O5Pureza:99.94%Cor e Forma:SolidPeso molecular:421.45NU6027
CAS:<p>NU6027 is a potent ATR/CDK inhibitor, inhibits CDK1/2, ATR and DNA-PK with Ki of 2.5 μM/1.3 μM, 0.4 μM and 2.2 μM, enter cells more readily than the 6-</p>Fórmula:C11H17N5O2Pureza:98.36%Cor e Forma:SolidPeso molecular:251.29ME0328
CAS:<p>ME0328 is a potent and selective PARP inhibitor with IC50 of 0.89 μM for PARP3, about 7-fold selectivity over PARP1.</p>Fórmula:C19H19N3O2Pureza:99.22%Cor e Forma:SolidPeso molecular:321.37Razoxane
CAS:<p>Razoxane is used as an antimitotic agent with immunosuppressive properties.</p>Fórmula:C11H16N4O4Pureza:99.75%Cor e Forma:SolidPeso molecular:268.27KU60019
CAS:<p>Ku-60019 is a potent, reversible inhibitor of ATM kinase (IC50: 6.3 nM). It is much less effective or without effect against a panel of 229 other kinases.</p>Fórmula:C30H33N3O5SPureza:95.9% - 99.36%Cor e Forma:SolidPeso molecular:547.67TH34
CAS:<p>TH34 is an HDAC6/8/10 inhibitor (IC50s: 4.6/1.9/7.7 μM). It shows high selectivity over HDAC1/2/3.</p>Fórmula:C15H16N2O2Pureza:98.32%Cor e Forma:SolidPeso molecular:256.3KCC-07
CAS:<p>KCC-07: Selective, potent, brain-penetrant MBD2 inhibitor with anticancer effects, blocking MBD2-DNA binding and activating BAI1 signaling.</p>Fórmula:C14H11N3OSPureza:98.86% - 99.01%Cor e Forma:SolidPeso molecular:269.32Triazavirin
CAS:<p>Triazavirin is a nucleoside analogue of nucleic acid and an antiviral agent.</p>Fórmula:C5H7N6NaO5SPureza:99.55%Cor e Forma:SolidPeso molecular:286.2Tasquinimod
CAS:<p>Tasquinimod (ABR-215050) is an oral antiangiogenic agent and S100A9 inhibitor that binds to the HDAC4Zn2+ binding structural domain with Kd values ranging from 10 to 30 nM.Cost-effective and quality-assured.</p>Fórmula:C20H17F3N2O4Pureza:99.22% - >99.99%Cor e Forma:SolidPeso molecular:406.36T0070907
CAS:<p>T0070907(IC50=1 nM) , an effective and specific PPARγ inhibitor, with the >800-fold selectivity over PPARα and PPARδ.</p>Fórmula:C12H8ClN3O3Pureza:98.25% - 99.98%Cor e Forma:SolidPeso molecular:277.66UBCS039
CAS:<p>UBCS039 is the first synthetic Sirt6 activator(EC50 : 38 μM)</p>Fórmula:C16H13N3Pureza:98.31%Cor e Forma:SolidPeso molecular:247.29PI-3065
CAS:<p>PI-3065 is a novel potent and selective PI3K p110δ inhibitor.</p>Fórmula:C27H31FN6OSPureza:99.84% - ≥95%Cor e Forma:SolidPeso molecular:506.64SRT 1720
CAS:<p>SRT 1720 is a selective activator of human SIRT1 (EC1.5: 0.16 μM) and is >230-fold less potent for SIRT2 and SIRT3.</p>Fórmula:C25H23N7OSPureza:98.84%Cor e Forma:SolidPeso molecular:469.56GW9662
CAS:<p>GW9662 (TIMTEC-BB SBB006523) is a PPARγ antagonist (IC50=3.3 nM) with selectivity. GW9662 has anti-tumor effect. High-Quality, Low-Cost!</p>Fórmula:C13H9ClN2O3Pureza:98% - 99.95%Cor e Forma:Off-White SolidPeso molecular:276.681,4-Naphthoquinone
CAS:<p>1,4-Naphthoquinone used as inhibitor for monoamine oxidase, DNA topoisomerase, and acetyltransferase.</p>Fórmula:C10H6O2Pureza:99.24% - 99.56%Cor e Forma:SolidPeso molecular:158.151-Hydroxyanthraquinone
CAS:<p>1-Hydroxyanthraquinone is an anthraquinone that has been found in Morinda officinalis and has genotoxic and carcinogenic activities.</p>Fórmula:C14H8O3Pureza:99.56%Cor e Forma:Orange Red Needles Red-Orange To Fine Yellow CrystalsPeso molecular:224.21Rubitecan
CAS:<p>Rubitecan: a semisynthetic DNA topoisomerase I inhibitor with antitumor and antiviral effects.</p>Fórmula:C20H15N3O6Pureza:97.54%Cor e Forma:Yellow Amorphous PowderPeso molecular:393.35AG14361
CAS:<p>AG14361 is an effective inhibitor of PARP1 (Ki<5 nM).</p>Fórmula:C19H20N4OPureza:98.7% - 99.93%Cor e Forma:SolidPeso molecular:320.39Gatifloxacin hydrochloride
CAS:<p>Gatifloxacin hydrochloride, a fourth-gen fluoroquinolone antibiotic, blocks bacterial DNA rotase and topoisomerase IV.</p>Fórmula:C19H23ClFN3O4Pureza:99.85% - 99.89%Cor e Forma:SolidPeso molecular:411.86EIDD-1931
CAS:<p>EIDD-1931 (Beta-d-N4-hydroxycytidine) is a ribonucleoside analog with antiviral activity. It inhibits replication of SARS-CoV, MERS-CoV, and SARS-CoV-2.</p>Fórmula:C9H13N3O6Pureza:99.14% - 99.73%Cor e Forma:SolidPeso molecular:259.22CXD101
CAS:<p>CXD101 is a novel class I-selective HDACi (HDAC1 (IC50 : 63nM), HDAC2 (IC50 :570nM), HDAC3 (IC50 :550nM)). CXD101(CXD-101) has no activity against HDAC class II</p>Fórmula:C24H29N5OPureza:99.82%Cor e Forma:SolidPeso molecular:403.521-Oleoyl lysophosphatidic acid sodium
CAS:<p>1-Oleoyl lysophosphatidic acid sodium (1-Oleoyl lysophosphatidic acid sodium salt) salt is an Endogenous agonist of LPA1 and LPA2</p>Fórmula:C21H40O7P·NaPureza:98.75% - 99.24%Cor e Forma:SolidPeso molecular:458.51MK-4827 Racemate
CAS:<p>MK-4827 Racemate (Niraparib Racemate) is a selective PARP1 and PARP2 inhibitor with IC50s of 3.8 nM and 2.1 nM, respectively, over 330-fold selectivity for</p>Fórmula:C19H20N4OPureza:99.86%Cor e Forma:SolidPeso molecular:320.39Cycloastragenol
CAS:<p>Cycloastragenol, a saponin from Astragalus, could be a new depression treatment.</p>Fórmula:C30H50O5Pureza:99.85% - 99.92%Cor e Forma:SolidPeso molecular:490.71GNE-3511
CAS:<p>GNE-3511 is a potent and selective dual leucine zipper kinase inhibitors.</p>Fórmula:C23H26F2N6OPureza:98.3% - 99.51%Cor e Forma:SolidPeso molecular:440.49PIK-93
CAS:PIK-93 is the first potent, synthetic PI4K inhibitor with IC50 of 19 nM; inhibits PI3Kα with IC50 of 39 nM.Fórmula:C14H16ClN3O4S2Pureza:97.72%Cor e Forma:SolidPeso molecular:389.889-Hydroxycamptothecin
CAS:<p>9-Hydroxycampothecin is a camptothecin derivative with anticancer activity.</p>Fórmula:C20H16N2O5Pureza:98.28%Cor e Forma:SolidPeso molecular:364.35Xanthosine 5'-monophosphate sodium salt
CAS:<p>Xanthosine 5'-monophosphate sodium salt (L-XMP Sodium) is an intermediate in purine metabolism.</p>Fórmula:C10H11N4Na2O9PPureza:99% - 99.77%Cor e Forma:SolidPeso molecular:408.17Deoxycytidine triphosphate
CAS:<p>dCTP is a nucleotide used in DNA synthesis, PCR, cDNA creation, and sequencing.</p>Fórmula:C9H16N3O13P3Pureza:99.68%Cor e Forma:SolidPeso molecular:467.16NKL 22
CAS:<p>NKL 22 (Histone Deacetylase Inhibitor IV) is an effective Histone Deacetylase Inhibitor.</p>Fórmula:C19H23N3O2Pureza:96.16% - 96.24%Cor e Forma:SolidPeso molecular:325.4AGK7
CAS:<p>AGK7 is an AGK2 control; it's a less selective SIRT2 inhibitor, with IC50s >5 μM for SIRT3, and >50 μM for SIRT1/2.</p>Fórmula:C23H13Cl2N3O2Pureza:98.31%Cor e Forma:SolidPeso molecular:434.27MN-64
CAS:<p>MN-64 is a tankyrases inhibitor, showed 6 nM potency against tankyrase 1, isoenzyme selectivity, and Wnt signaling inhibition.</p>Fórmula:C18H16O2Pureza:99.5% - 99.93%Cor e Forma:SolidPeso molecular:264.32E7449
CAS:<p>E7449 is a potent inhibitor of PARP1, PARP2, TNKS1, and TNKS2 with IC50s of 2, 1, ~50, and ~50 nM respectively.</p>Fórmula:C18H15N5OPureza:97.13%Cor e Forma:SolidPeso molecular:317.34Methotrexate disodium
CAS:<p>Methotrexate disodium is an tetrahydrofolate dehydrogenase inhibitor</p>Fórmula:C20H20N8Na2O5Pureza:99.77% - 99.96%Cor e Forma:SolidPeso molecular:498.4AZD-7648
CAS:<p>AZD-7648 is an inhibitor of DNA-dependent protein kinase (DNA-PK) with the IC50 of 0.63 nM in an enzyme assay,has anti-tumor activity.</p>Fórmula:C18H20N8O2Pureza:99.03% - 99.85%Cor e Forma:SolidPeso molecular:380.4AZ6102
CAS:<p>AZ6102: Potent TNKS1/2 inhibitor, 100x selective over PARPs, IC50 = 5 nM in DLD-1 Wnt pathway.</p>Fórmula:C25H28N6OPureza:97.98% - 99.91%Cor e Forma:SolidPeso molecular:428.53OUL35
CAS:<p>OUL35 (NSC-39047) is a selective PARP-10 inhibitor, and small-molecule ARTD10 inhibitor. OUL35 has been shown to rescue cells from ARTD10-induced cell death.</p>Fórmula:C14H12N2O3Pureza:99.2%Cor e Forma:SolidPeso molecular:256.26AG-494
CAS:<p>AG-494 (Tyrphostin B48) is an inhibitor of epidermal growth factor receptor kinase.</p>Fórmula:C16H12N2O3Pureza:98.69%Cor e Forma:SolidPeso molecular:280.28Clofibrate
CAS:<p>Clofibrate (Clofibrato) is an aryloxyisobutyric acid derivate with antihyperlipidemic activity.</p>Fórmula:C12H15ClO3Pureza:98.77%Cor e Forma:Oil LiquidPeso molecular:242.70Selisistat S-enantiomer
CAS:<p>Selisistat S-enantiomer (EX-527 S-enantiomer) is an effective and specific SIRT1 inhibitor (IC50 = 98 nM) and shows >200-fold selectivity against SIRT2/3.</p>Fórmula:C13H13ClN2OPureza:99.86%Cor e Forma:SolidPeso molecular:248.71Suramin Sodium Salt
CAS:<p>Suramin Sodium Salt (BAY-205) is a polysulphonated naphthylurea with potential antineoplastic activity. Suramin blocks the binding of various growth factors.</p>Fórmula:C51H34N6Na6O23S6Pureza:97.47% - 99.97%Cor e Forma:WhitePeso molecular:1429.15Citarinostat
CAS:<p>ACY-241 (Citarinostat), a potent oral HDAC inhibitor, may induce tumor cell death and block growth by altering gene expression.</p>Fórmula:C24H26ClN5O3Pureza:98.06% - 99.06%Cor e Forma:SolidPeso molecular:467.95Pamiparib
CAS:<p>Pamiparib (BGB-290) is an orally active, potent, highly selective PARP inhibitor. It has potent PARP trapping, and capability to penetrate the brain.</p>Fórmula:C16H15FN4OPureza:99.69%Cor e Forma:SolidPeso molecular:298.31Fluzoparib
CAS:<p>Fluzoparib (SHR3162) is a novel, potent, and orally available inhibitor of PARP, potentially for the treatment of solid tumours.</p>Fórmula:C22H16F4N6O2Pureza:98.53% - 99.63%Cor e Forma:SolidPeso molecular:472.4Bisantrene
CAS:<p>Bisantrene, an anthracene derivative, targets DNA causing breaks and replication inhibition; it's like doxorubicin minus the cardiotoxicity.</p>Fórmula:C22H22N8Pureza:96.07% - 98.57%Cor e Forma:SolidPeso molecular:398.46DMNB
CAS:<p>DMNB (6-Nitroveratraldehyde) is DNA-dependent protein kinase (DNA-PK) inhibitor, an enzyme involved in the NHEJ pathway of DSB repair in human cells.</p>Fórmula:C9H9NO5Pureza:97.87%Cor e Forma:Yellow SolidPeso molecular:211.17Bobcat339
CAS:<p>Bobcat339 is a novel cytosine-based TET enzyme inhibitor (IC50s: 33/73 uM for TET1/2), but not DNMT3a, does not inhibit the DNA methyltransferase DNMT3a.</p>Fórmula:C16H12ClN3OPureza:97.79% - 99.24%Cor e Forma:SolidPeso molecular:297.74CGK733
CAS:<p>CGK733 (CGK 733) is a potent and selective inhibitor of ATM/ATR.</p>Fórmula:C23H18Cl3FN4O3SPureza:98% - 99.67%Cor e Forma:SolidPeso molecular:555.84AZD 6482
CAS:<p>AZD 6482 (KIN-193) is a potent and selective inhibitor of p110β and PI3Kβ with IC50 values of 0.69nM and 10nM.Cost-effective and quality-assured.</p>Fórmula:C22H24N4O4Pureza:99.79% - 99.95%Cor e Forma:SolidPeso molecular:408.452-Aminopurine
CAS:<p>2-Aminopurine is a double-stranded RNA-dependent protein kinase, protein kinase R (PKR) inhibitor.</p>Fórmula:C5H5N5Pureza:99.51%Cor e Forma:White To Light Yellow Crystal PowderPeso molecular:135.13Compound 401
CAS:<p>Compound 401 (2-morpholino-4H-pyrimido[2,1-a]isoquinolin-4-one) is a synthetic DNA-PK inhibitor (IC50 = 0.28 μM) that also targets mTOR but not PI3K.</p>Fórmula:C16H15N3O2Pureza:99.73% - 99.78%Cor e Forma:SolidPeso molecular:281.31Selisistat R-enantiomer
CAS:<p>Selisistat R-enantiomer (EX-527 (R-enantiomer)) is a SIRT1 inhibitor with much less activity than the R-enantiomer of Selisistat (IC50 of SIRT1 > 100 μM).</p>Fórmula:C13H13ClN2OPureza:99.8%Cor e Forma:SolidPeso molecular:248.71G007-LK
CAS:<p>G007-LK is a selective inhibitor of TNKS1 and TNKS2, with IC50s of 46 nM and 25 nM, respectively.</p>Fórmula:C25H16ClN7O3SPureza:97.63% - 98.17%Cor e Forma:SolidPeso molecular:529.96Trabectedin
CAS:<p>Trabectedin (Ecteinascidin 743) has potent antitumor activity and the potential for soft tissue sarcoma and ovarian cancer research.</p>Fórmula:C39H43N3O11SPureza:≥98%Cor e Forma:SolidPeso molecular:761.84Niraparib tosylate monohyrate
CAS:Niraparib (MK-4827), a PARP inhibitor, boosts DNA breaks to trigger genomic instability and apoptosis, offering anti-cancer effects.Fórmula:C26H30N4O5SPureza:97.7% - 98.41%Cor e Forma:SolidPeso molecular:510.61Isosteviol
CAS:<p>Isosteviol is a natural sweetener with anti-inflammatory, anti-tumor, glucose-lowering, and other health benefits.</p>Fórmula:C20H30O3Pureza:99.72% - 99.97%Cor e Forma:SolidPeso molecular:318.45SW044248
CAS:<p>SW044248 is a noncanonical Top1 inhibitor. It has selective toxicity for NSCLC cells.</p>Fórmula:C22H23N5O2SPureza:99.56% - 99.87%Cor e Forma:SolidPeso molecular:421.52CM-272
CAS:<p>CM-272 is a dual G9a/DNA methyltransferases (DNMTs) inhibitor.</p>Fórmula:C28H38N4O3Pureza:97.83%Cor e Forma:SolidPeso molecular:478.63LY294002
CAS:<p>LY294002 (SF 1101) is a broad-spectrum inhibitor of PI3K, inhibiting PI3Kα, PI3Kδ, and PI3Kβ (IC50=0.5/0.57/0.97 μM).</p>Fórmula:C19H17NO3Pureza:98% - 99.96%Cor e Forma:Pale Yellow SolidPeso molecular:307.34Torin 2
CAS:<p>Torin 2: mTOR inhibitor, IC50=0.25 nM, 800x more selective than PI3K, with EC50=28/35/118 nM for ATM/ATR/DNA-PK.</p>Fórmula:C24H15F3N4OPureza:98.31% - 99.32%Cor e Forma:SolidPeso molecular:432.4Cardioxane
CAS:<p>Cardioxane (ADR-529) is a cardio-protective drug.</p>Fórmula:C11H16N4O4·HClPureza:98.08%Cor e Forma:SolidPeso molecular:304.73Adefovir
CAS:<p>Adefovir: acyclic nucleoside phosphonate, reverse transcriptase inhibitor for hepatitis B and herpes treatment.</p>Fórmula:C8H12N5O4PPureza:99.56%Cor e Forma:White To Off-White PowderPeso molecular:273.19PJ34 hydrochloride
CAS:<p>PJ34 hydrochloride (PJ34 HCl) is a potent specific inhibitor of PARPl/2.</p>Fórmula:C17H18ClN3O2Pureza:98.87% - ≥95%Cor e Forma:SolidPeso molecular:331.8SRT 2104
CAS:<p>SRT 2104 (GSK2245840) is a selective and brain-permeable SIRT1 activator.</p>Fórmula:C26H24N6O2S2Pureza:98.34% - 99.82%Cor e Forma:SolidPeso molecular:516.64Leniolisib
CAS:<p>Leniolisib (CDZ173) (CDZ173) is a potent and selective PI3Kδ inhibitor (IC50: 11 nM).</p>Fórmula:C21H25F3N6O2Pureza:99.88%Cor e Forma:SolidPeso molecular:450.46
