Dano de DNA/Reparo de DNA
Os inibidores de dano/ reparo do DNA são compostos que interferem nos processos envolvidos na detecção e reparo de danos ao DNA. Esses inibidores são fundamentais para estudar os mecanismos de estabilidade genômica, mutagênese e resposta ao dano ao DNA. Eles também são importantes na pesquisa do câncer, pois muitos tumores dependem de vias específicas de reparo de DNA para sobreviver. Ao inibir essas vias, os inibidores de dano/reparo de DNA podem aumentar a eficácia da quimioterapia e da radioterapia. Na CymitQuimica, oferecemos uma ampla gama de inibidores de alta qualidade de dano/reparo de DNA para apoiar sua pesquisa em biologia molecular, oncologia e farmacologia.
Subcategorias de "Dano de DNA/Reparo de DNA"
- ATM/ATR(71 produtos)
- Alquilação de DNA(11 produtos)
- DNA Metiltransferase(421 produtos)
- DNA girase(11 produtos)
- DNA-PK(51 produtos)
- MTH1(1 produtos)
- Nucleosídeo Antimetabólito/Análogo(1.388 produtos)
- Transcriptase reversa(43 produtos)
- Sirtuína(88 produtos)
- Telomerase(33 produtos)
- Topoisomerase(136 produtos)
Exibir 3 mais subcategorias
Foram encontrados 958 produtos de "Dano de DNA/Reparo de DNA"
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Torin 1
CAS:<p>Torin 1 is an effective inhibitor of mTORC1/2 with (IC50: 2 nM/10 nM); has 1000-fold selectivity for mTOR than PI3K.</p>Fórmula:C35H28F3N5O2Pureza:98.3% - 99.33%Cor e Forma:SolidPeso molecular:607.62Adenine hydrochloride
CAS:<p>Adenine hydrochloride (6-Aminopurine hydrochloride) is a hydrochloride salt form of adenine which is a nucleobase with a variety of roles in biochemistry.</p>Fórmula:C5H5N5·HClPureza:98.86%Cor e Forma:White To Light Yellow Crystal PowderPeso molecular:171.59ITSA-1
CAS:<p>ITSA-1 is membrane permeable and specifically suppresses TSA inhibition of HDAC (histone deacetylase), but shows no activity towards other HDAC inhibitors.</p>Fórmula:C13H7Cl2N3OPureza:99.78% - 99.89%Cor e Forma:SolidPeso molecular:292.12SirReal2
CAS:<p>SirReal2 is a potent and selective Sirt2 inhibitor with IC50 of 140 nM.</p>Fórmula:C22H20N4OS2Pureza:98.96% - 99.75%Cor e Forma:SolidPeso molecular:420.55GSK3685032
CAS:<p>GSK3685032 is a non-covalent and selective DNMT1 inhibitor(IC50 = 36 nM).</p>Fórmula:C22H24N6OSPureza:98.56% - 99.49%Cor e Forma:SolidPeso molecular:420.53NU 7026
CAS:<p>NU 7026 (DNA-PK Inhibitor II) is an effective DNA-PK inhibitor (IC50: 0.23 μM, in cell-free assays), 60-fold selective for DNA-PK than PI3K and no inhibition</p>Fórmula:C17H15NO3Pureza:99.51% - >99.99%Cor e Forma:SolidPeso molecular:281.31Hinokitiol
CAS:<p>Hinokitiol prevents UVB-caused cell death, boosts antioxidant activity, and hinders breast cancer growth.</p>Fórmula:C10H12O2Pureza:99.49% - 99.67%Cor e Forma:SolidPeso molecular:164.2Carmustine
CAS:<p>Carmustine (bis-chloroethylnitrosourea) is a cell-cycle phase nonspecific alkylating antineoplastic agent.</p>Fórmula:C5H9Cl2N3O2Pureza:98% - 99.91%Cor e Forma:Light Yellow Powder Physical Description Orange-Yellow Solid (Ntp 1992)Peso molecular:214.05VAL-083
CAS:<p>VAL-083 (Dianhydrogalactitol) is an alkylating compound that creates N7 methylation on DNA. It also has antitumor activity.</p>Fórmula:C6H10O4Pureza:97.94%Cor e Forma:SolidPeso molecular:146.14PI3K-IN-1
CAS:<p>PI3K-IN-1 (Voxtalisib Analogue) is a dual inhibitor of mTOR/PI3K, mostly for p110γ , also inhibits DNA-PK and mTOR.</p>Fórmula:C31H29N5O6SPureza:97.03% - 98%Cor e Forma:SolidPeso molecular:599.66Niraparib
CAS:<p>Niraparib (MK-4827) inhibits PARP1/PARP2 (IC50: 3.8/2.1 nM), effective on BRCA mutant cancers, 330x less effective on PARP3, V-PARP, Tank1.</p>Fórmula:C19H20N4OPureza:98% - 99.91%Cor e Forma:SolidPeso molecular:320.39FIT-039
CAS:<p>FIT-039 is a selective and ATP-competitive, orally active inhibitor of CDK9( IC50 : 5.8 μM;CDK9/cyclin T1).</p>Fórmula:C17H18FN3SPureza:98.61%Cor e Forma:SolidPeso molecular:315.41BRD7116
CAS:<p>BRD7116 competitively binds to bacterial DNA gyrase, with cell-non-autonomous anti-leukemia activity.</p>Fórmula:C28H36N2O4SPureza:99.69% - 99.91%Cor e Forma:SolidPeso molecular:496.66Adenine hemisulfate
CAS:<p>Adenine hemisulfate (Diadenine sulphate) is a sulfate salt form of adenine which is a purine derivative and a nucleobase with a variety of roles in biochemistry</p>Fórmula:(C5H5N5)·H2SO4Pureza:99.48%Cor e Forma:White To Light Yellow Crystal PowderPeso molecular:368.33BIBR 1532
CAS:<p>BIBR 1532 is an effective, specific and non-competitive telomerase inhibitor (IC50: 100 nM, in a cell-free assay).</p>Fórmula:C21H17NO3Pureza:98.49% - 98.90%Cor e Forma:SolidPeso molecular:331.364-amino-1,8-Naphthalimide
CAS:<p>4-amino-1,8-Naphthalimide (4-ANI) is a PARP inhibitor with IC50 of 180 nM</p>Fórmula:C12H8N2O2Pureza:95.13%Cor e Forma:Yellow Solid PowderPeso molecular:212.2NMS-P118
CAS:<p>NMS-P118 is a potent, selective and orally available Inhibitor of PARP-1 for cancer therapy.</p>Fórmula:C20H24F3N3O2Pureza:98.79%Cor e Forma:SolidPeso molecular:395.42CP-466722
CAS:<p>CP-466722, an effective and reversible ATM inhibitor, does not inhibit ATR and PI3K or PIKK family members in cells.</p>Fórmula:C17H15N7O2Pureza:99.1% - 99.14%Cor e Forma:SolidPeso molecular:349.35CAY10603
CAS:<p>CAY10603 (BML-281) is a potent and selective inhibitor of HDAC6.</p>Fórmula:C22H30N4O6Pureza:95.75% - 98.1%Cor e Forma:SolidPeso molecular:446.5RK-287107
CAS:<p>RK-287107 is an effective and specific inhibitor of tankyrase (IC50s: 14.3 and 10.6 nM for tankyrase-1 and tankyrase-2, respectively).</p>Fórmula:C22H26F2N4O2Pureza:99.64%Cor e Forma:SolidPeso molecular:416.46Thiacloprid
CAS:<p>Thiacloprid: insecticide targeting insect nAChRs, IC50 - Drosophila: 2.7 nM, Mouse α4β2 nAChRs: 860 nM.</p>Fórmula:C10H9ClN4SPureza:98.66% - 99.95%Cor e Forma:Yellowish Crystalline PowderPeso molecular:252.72Ciprofloxacin hydrochloride monohydrate
CAS:<p>Ciprofloxacin hydrochloride monohydrate (Bay-09867 hydrochloride monohydrate) is a fluoroquinolone antibiotic with potent antibacterial activity.</p>Fórmula:C17H21ClFN3O4Pureza:99.23% - 99.85%Cor e Forma:White Or Yellowish Crystalline PowderPeso molecular:385.82Pentamidine dihydrochloride
CAS:<p>Pentamidine dihydrochloride (MP-601205 dihydrochloride) is an aromatic diamidine agent with activity against a number of microorganisms including protozoa (</p>Fórmula:C19H26Cl2N4O2Pureza:99.80%Cor e Forma:SolidPeso molecular:413.34Silver sulfadiazine
CAS:<p>Silver sulfadiazine (Dermazin) is a sulfonamide-based topical agent with antibacterial and antifungal activity.</p>Fórmula:C10H9AgN4O2SPureza:99.04% - 99.58%Cor e Forma:SolidPeso molecular:357.14BCH001
CAS:<p>BCH001 is a specific small-molecule inhibitor of PAPD5.</p>Fórmula:C20H15F3N2O5Pureza:99.06%Cor e Forma:SolidPeso molecular:420.34NU2058
CAS:<p>NU2058 (O(6)-Cyclohexylmethylguanine) is a guanine-based CDK inhibitor, also inhibits DNA topoisomerase II ATPase activity.</p>Fórmula:C12H17N5OPureza:99.34% - 99.92%Cor e Forma:SolidPeso molecular:247.3Pentamidine isethionate
CAS:<p>Pentamidine isethionate (Pentamidine diisethionate) is a synthetic amidine derivative, Pentamidine Isethionate is an antiprotozoal and antifungal agent.</p>Fórmula:C23H36N4O10S2Pureza:98% - 99.83%Cor e Forma:Slight Butyric Odor Very Bitter Taste Ph (5% Aqueous Solution) 4 5-6 5 (Ntp 1992)Peso molecular:592.68Trifluridine/tipiracil hydrochloride mixture
CAS:<p>Trifluridine/tipiracil hydrochloride mixture (TAS-102) is a novel oral combination drug containing trifluridine (TFT) and Tipiracil hydrochloride (TTP) in a</p>Fórmula:C29H34Cl2F6N8O12Pureza:98% - 99.79%Cor e Forma:SolidPeso molecular:871.53Remodelin hydrobromide
CAS:<p>Remodelin hydrobromide (Remodelin HBR) is a novel potent and selective inhibitor of the acetyl-transferase protein NAT10.</p>Fórmula:C15H15BrN4SPureza:97.22% - 99.84%Cor e Forma:SolidPeso molecular:363.275Rucaparib Phosphate
CAS:<p>Rucaparib Phosphate (PF-01367338 phosphate) is an inhibitor of PARP that is used in clinical therapy to sensitize cancer cells to chemotherapy.</p>Fórmula:C19H18FN3O·H3PO4Pureza:99.37%Cor e Forma:SolidPeso molecular:421.36Trovafloxacin
CAS:<p>Trovafloxacin, a broad-spectrum quinolone antibiotic, exhibits potent activity against Gram-positive bacteria.</p>Fórmula:C20H15F3N4O3Pureza:99.21% - 99.27%Cor e Forma:SolidPeso molecular:416.35Dxd
CAS:<p>Dxd (OQM5SD32BQ) is a potent DNA topoisomerase I inhibitor (IC50= 0.31 μM). Dxd was used as a conjugate drug for HER2-targeted ADCs. High-Quality, Low-Cost!</p>Fórmula:C26H24FN3O6Pureza:98.21% - ≥98%Cor e Forma:SolidPeso molecular:493.48Bendamustine
CAS:<p>Bendamustine (SDX105) for the treatment of Non-Hodgkin Lymphomas and Chronic Lymphocytic Leukemia</p>Fórmula:C16H21Cl2N3O2Pureza:≥98%Cor e Forma:SolidPeso molecular:358.26Clomesone
CAS:<p>Clomesone, a synthetic drug, treats female infertility by blocking brain estrogen, inducing ovulation.</p>Fórmula:C4H9ClO5S2Pureza:99%Cor e Forma:SolidPeso molecular:236.69AZ20
CAS:<p>AZ20 is an effective and specific inhibitor of ATR kinase (IC50: 5 nM, in a cell-free assay), 8-fold selectivity over mTOR.</p>Fórmula:C21H24N4O3SPureza:98% - 99.69%Cor e Forma:SolidPeso molecular:412.51Topovale
CAS:<p>Topovale (ARC111) is a potent inhibitor of topoisomerase I.</p>Fórmula:C23H23N3O5Pureza:99.94%Cor e Forma:SolidPeso molecular:421.45NU6027
CAS:<p>NU6027 is a potent ATR/CDK inhibitor, inhibits CDK1/2, ATR and DNA-PK with Ki of 2.5 μM/1.3 μM, 0.4 μM and 2.2 μM, enter cells more readily than the 6-</p>Fórmula:C11H17N5O2Pureza:98.36%Cor e Forma:SolidPeso molecular:251.29ME0328
CAS:<p>ME0328 is a potent and selective PARP inhibitor with IC50 of 0.89 μM for PARP3, about 7-fold selectivity over PARP1.</p>Fórmula:C19H19N3O2Pureza:99.22%Cor e Forma:SolidPeso molecular:321.37Razoxane
CAS:<p>Razoxane is used as an antimitotic agent with immunosuppressive properties.</p>Fórmula:C11H16N4O4Pureza:99.75%Cor e Forma:SolidPeso molecular:268.27KU60019
CAS:<p>Ku-60019 is a potent, reversible inhibitor of ATM kinase (IC50: 6.3 nM). It is much less effective or without effect against a panel of 229 other kinases.</p>Fórmula:C30H33N3O5SPureza:95.9% - 99.36%Cor e Forma:SolidPeso molecular:547.67TH34
CAS:<p>TH34 is an HDAC6/8/10 inhibitor (IC50s: 4.6/1.9/7.7 μM). It shows high selectivity over HDAC1/2/3.</p>Fórmula:C15H16N2O2Pureza:98.32%Cor e Forma:SolidPeso molecular:256.3KCC-07
CAS:<p>KCC-07: Selective, potent, brain-penetrant MBD2 inhibitor with anticancer effects, blocking MBD2-DNA binding and activating BAI1 signaling.</p>Fórmula:C14H11N3OSPureza:98.86% - 99.01%Cor e Forma:SolidPeso molecular:269.32Triazavirin
CAS:<p>Triazavirin is a nucleoside analogue of nucleic acid and an antiviral agent.</p>Fórmula:C5H7N6NaO5SPureza:99.55%Cor e Forma:SolidPeso molecular:286.2Tasquinimod
CAS:<p>Tasquinimod (ABR-215050) is an oral antiangiogenic agent and S100A9 inhibitor that binds to the HDAC4Zn2+ binding structural domain with Kd values ranging from 10 to 30 nM.Cost-effective and quality-assured.</p>Fórmula:C20H17F3N2O4Pureza:99.22% - >99.99%Cor e Forma:SolidPeso molecular:406.36T0070907
CAS:<p>T0070907(IC50=1 nM) , an effective and specific PPARγ inhibitor, with the >800-fold selectivity over PPARα and PPARδ.</p>Fórmula:C12H8ClN3O3Pureza:98.25% - 99.98%Cor e Forma:SolidPeso molecular:277.66UBCS039
CAS:<p>UBCS039 is the first synthetic Sirt6 activator(EC50 : 38 μM)</p>Fórmula:C16H13N3Pureza:98.31%Cor e Forma:SolidPeso molecular:247.29PI-3065
CAS:<p>PI-3065 is a novel potent and selective PI3K p110δ inhibitor.</p>Fórmula:C27H31FN6OSPureza:99.84% - ≥95%Cor e Forma:SolidPeso molecular:506.64SRT 1720
CAS:<p>SRT 1720 is a selective activator of human SIRT1 (EC1.5: 0.16 μM) and is >230-fold less potent for SIRT2 and SIRT3.</p>Fórmula:C25H23N7OSPureza:98.84%Cor e Forma:SolidPeso molecular:469.56GW9662
CAS:<p>GW9662 (TIMTEC-BB SBB006523) is a PPARγ antagonist (IC50=3.3 nM) with selectivity. GW9662 has anti-tumor effect. High-Quality, Low-Cost!</p>Fórmula:C13H9ClN2O3Pureza:98% - 99.95%Cor e Forma:Off-White SolidPeso molecular:276.681,4-Naphthoquinone
CAS:<p>1,4-Naphthoquinone used as inhibitor for monoamine oxidase, DNA topoisomerase, and acetyltransferase.</p>Fórmula:C10H6O2Pureza:99.24% - 99.56%Cor e Forma:SolidPeso molecular:158.151-Hydroxyanthraquinone
CAS:<p>1-Hydroxyanthraquinone is an anthraquinone that has been found in Morinda officinalis and has genotoxic and carcinogenic activities.</p>Fórmula:C14H8O3Pureza:99.56%Cor e Forma:Orange Red Needles Red-Orange To Fine Yellow CrystalsPeso molecular:224.21Rubitecan
CAS:<p>Rubitecan: a semisynthetic DNA topoisomerase I inhibitor with antitumor and antiviral effects.</p>Fórmula:C20H15N3O6Pureza:97.54%Cor e Forma:Yellow Amorphous PowderPeso molecular:393.35AG14361
CAS:<p>AG14361 is an effective inhibitor of PARP1 (Ki<5 nM).</p>Fórmula:C19H20N4OPureza:98.7% - 99.93%Cor e Forma:SolidPeso molecular:320.39Gatifloxacin hydrochloride
CAS:<p>Gatifloxacin hydrochloride, a fourth-gen fluoroquinolone antibiotic, blocks bacterial DNA rotase and topoisomerase IV.</p>Fórmula:C19H23ClFN3O4Pureza:99.85% - 99.89%Cor e Forma:SolidPeso molecular:411.86EIDD-1931
CAS:<p>EIDD-1931 (Beta-d-N4-hydroxycytidine) is a ribonucleoside analog with antiviral activity. It inhibits replication of SARS-CoV, MERS-CoV, and SARS-CoV-2.</p>Fórmula:C9H13N3O6Pureza:99.14% - 99.73%Cor e Forma:SolidPeso molecular:259.22CXD101
CAS:<p>CXD101 is a novel class I-selective HDACi (HDAC1 (IC50 : 63nM), HDAC2 (IC50 :570nM), HDAC3 (IC50 :550nM)). CXD101(CXD-101) has no activity against HDAC class II</p>Fórmula:C24H29N5OPureza:99.82%Cor e Forma:SolidPeso molecular:403.521-Oleoyl lysophosphatidic acid sodium
CAS:<p>1-Oleoyl lysophosphatidic acid sodium (1-Oleoyl lysophosphatidic acid sodium salt) salt is an Endogenous agonist of LPA1 and LPA2</p>Fórmula:C21H40O7P·NaPureza:98.75% - 99.24%Cor e Forma:SolidPeso molecular:458.51MK-4827 Racemate
CAS:<p>MK-4827 Racemate (Niraparib Racemate) is a selective PARP1 and PARP2 inhibitor with IC50s of 3.8 nM and 2.1 nM, respectively, over 330-fold selectivity for</p>Fórmula:C19H20N4OPureza:99.86%Cor e Forma:SolidPeso molecular:320.39Cycloastragenol
CAS:<p>Cycloastragenol, a saponin from Astragalus, could be a new depression treatment.</p>Fórmula:C30H50O5Pureza:99.85% - 99.92%Cor e Forma:SolidPeso molecular:490.71GNE-3511
CAS:<p>GNE-3511 is a potent and selective dual leucine zipper kinase inhibitors.</p>Fórmula:C23H26F2N6OPureza:98.3% - 99.51%Cor e Forma:SolidPeso molecular:440.49PIK-93
CAS:PIK-93 is the first potent, synthetic PI4K inhibitor with IC50 of 19 nM; inhibits PI3Kα with IC50 of 39 nM.Fórmula:C14H16ClN3O4S2Pureza:97.72%Cor e Forma:SolidPeso molecular:389.889-Hydroxycamptothecin
CAS:<p>9-Hydroxycampothecin is a camptothecin derivative with anticancer activity.</p>Fórmula:C20H16N2O5Pureza:98.28%Cor e Forma:SolidPeso molecular:364.35Xanthosine 5'-monophosphate sodium salt
CAS:<p>Xanthosine 5'-monophosphate sodium salt (L-XMP Sodium) is an intermediate in purine metabolism.</p>Fórmula:C10H11N4Na2O9PPureza:99% - 99.77%Cor e Forma:SolidPeso molecular:408.17Deoxycytidine triphosphate
CAS:<p>dCTP is a nucleotide used in DNA synthesis, PCR, cDNA creation, and sequencing.</p>Fórmula:C9H16N3O13P3Pureza:99.68%Cor e Forma:SolidPeso molecular:467.16NKL 22
CAS:<p>NKL 22 (Histone Deacetylase Inhibitor IV) is an effective Histone Deacetylase Inhibitor.</p>Fórmula:C19H23N3O2Pureza:96.16% - 96.24%Cor e Forma:SolidPeso molecular:325.4AGK7
CAS:<p>AGK7 is an AGK2 control; it's a less selective SIRT2 inhibitor, with IC50s >5 μM for SIRT3, and >50 μM for SIRT1/2.</p>Fórmula:C23H13Cl2N3O2Pureza:98.31%Cor e Forma:SolidPeso molecular:434.27MN-64
CAS:<p>MN-64 is a tankyrases inhibitor, showed 6 nM potency against tankyrase 1, isoenzyme selectivity, and Wnt signaling inhibition.</p>Fórmula:C18H16O2Pureza:99.5% - 99.93%Cor e Forma:SolidPeso molecular:264.32E7449
CAS:<p>E7449 is a potent inhibitor of PARP1, PARP2, TNKS1, and TNKS2 with IC50s of 2, 1, ~50, and ~50 nM respectively.</p>Fórmula:C18H15N5OPureza:97.13%Cor e Forma:SolidPeso molecular:317.34Methotrexate disodium
CAS:<p>Methotrexate disodium is an tetrahydrofolate dehydrogenase inhibitor</p>Fórmula:C20H20N8Na2O5Pureza:99.77% - 99.96%Cor e Forma:SolidPeso molecular:498.4AZD-7648
CAS:<p>AZD-7648 is an inhibitor of DNA-dependent protein kinase (DNA-PK) with the IC50 of 0.63 nM in an enzyme assay,has anti-tumor activity.</p>Fórmula:C18H20N8O2Pureza:99.03% - 99.85%Cor e Forma:SolidPeso molecular:380.4AZ6102
CAS:<p>AZ6102: Potent TNKS1/2 inhibitor, 100x selective over PARPs, IC50 = 5 nM in DLD-1 Wnt pathway.</p>Fórmula:C25H28N6OPureza:97.98% - 99.91%Cor e Forma:SolidPeso molecular:428.53OUL35
CAS:<p>OUL35 (NSC-39047) is a selective PARP-10 inhibitor, and small-molecule ARTD10 inhibitor. OUL35 has been shown to rescue cells from ARTD10-induced cell death.</p>Fórmula:C14H12N2O3Pureza:99.2%Cor e Forma:SolidPeso molecular:256.26AG-494
CAS:<p>AG-494 (Tyrphostin B48) is an inhibitor of epidermal growth factor receptor kinase.</p>Fórmula:C16H12N2O3Pureza:98.69%Cor e Forma:SolidPeso molecular:280.28Clofibrate
CAS:<p>Clofibrate (Clofibrato) is an aryloxyisobutyric acid derivate with antihyperlipidemic activity.</p>Fórmula:C12H15ClO3Pureza:98.77%Cor e Forma:Oil LiquidPeso molecular:242.70Selisistat S-enantiomer
CAS:<p>Selisistat S-enantiomer (EX-527 S-enantiomer) is an effective and specific SIRT1 inhibitor (IC50 = 98 nM) and shows >200-fold selectivity against SIRT2/3.</p>Fórmula:C13H13ClN2OPureza:99.86%Cor e Forma:SolidPeso molecular:248.71Suramin Sodium Salt
CAS:<p>Suramin Sodium Salt (BAY-205) is a polysulphonated naphthylurea with potential antineoplastic activity. Suramin blocks the binding of various growth factors.</p>Fórmula:C51H34N6Na6O23S6Pureza:97.47% - 99.97%Cor e Forma:WhitePeso molecular:1429.15Citarinostat
CAS:<p>ACY-241 (Citarinostat), a potent oral HDAC inhibitor, may induce tumor cell death and block growth by altering gene expression.</p>Fórmula:C24H26ClN5O3Pureza:98.06% - 99.06%Cor e Forma:SolidPeso molecular:467.95Pamiparib
CAS:<p>Pamiparib (BGB-290) is an orally active, potent, highly selective PARP inhibitor. It has potent PARP trapping, and capability to penetrate the brain.</p>Fórmula:C16H15FN4OPureza:99.69%Cor e Forma:SolidPeso molecular:298.31Fluzoparib
CAS:<p>Fluzoparib (SHR3162) is a novel, potent, and orally available inhibitor of PARP, potentially for the treatment of solid tumours.</p>Fórmula:C22H16F4N6O2Pureza:98.53% - 99.63%Cor e Forma:SolidPeso molecular:472.4Bisantrene
CAS:<p>Bisantrene, an anthracene derivative, targets DNA causing breaks and replication inhibition; it's like doxorubicin minus the cardiotoxicity.</p>Fórmula:C22H22N8Pureza:96.07% - 98.57%Cor e Forma:SolidPeso molecular:398.46DMNB
CAS:<p>DMNB (6-Nitroveratraldehyde) is DNA-dependent protein kinase (DNA-PK) inhibitor, an enzyme involved in the NHEJ pathway of DSB repair in human cells.</p>Fórmula:C9H9NO5Pureza:97.87%Cor e Forma:Yellow SolidPeso molecular:211.17Bobcat339
CAS:<p>Bobcat339 is a novel cytosine-based TET enzyme inhibitor (IC50s: 33/73 uM for TET1/2), but not DNMT3a, does not inhibit the DNA methyltransferase DNMT3a.</p>Fórmula:C16H12ClN3OPureza:97.79% - 99.24%Cor e Forma:SolidPeso molecular:297.74CGK733
CAS:<p>CGK733 (CGK 733) is a potent and selective inhibitor of ATM/ATR.</p>Fórmula:C23H18Cl3FN4O3SPureza:98% - 99.67%Cor e Forma:SolidPeso molecular:555.84AZD 6482
CAS:<p>AZD 6482 (KIN-193) is a potent and selective inhibitor of p110β and PI3Kβ with IC50 values of 0.69nM and 10nM.Cost-effective and quality-assured.</p>Fórmula:C22H24N4O4Pureza:99.79% - 99.95%Cor e Forma:SolidPeso molecular:408.452-Aminopurine
CAS:<p>2-Aminopurine is a double-stranded RNA-dependent protein kinase, protein kinase R (PKR) inhibitor.</p>Fórmula:C5H5N5Pureza:99.51%Cor e Forma:White To Light Yellow Crystal PowderPeso molecular:135.13Compound 401
CAS:<p>Compound 401 (2-morpholino-4H-pyrimido[2,1-a]isoquinolin-4-one) is a synthetic DNA-PK inhibitor (IC50 = 0.28 μM) that also targets mTOR but not PI3K.</p>Fórmula:C16H15N3O2Pureza:99.73% - 99.78%Cor e Forma:SolidPeso molecular:281.31Selisistat R-enantiomer
CAS:<p>Selisistat R-enantiomer (EX-527 (R-enantiomer)) is a SIRT1 inhibitor with much less activity than the R-enantiomer of Selisistat (IC50 of SIRT1 > 100 μM).</p>Fórmula:C13H13ClN2OPureza:99.8%Cor e Forma:SolidPeso molecular:248.71G007-LK
CAS:<p>G007-LK is a selective inhibitor of TNKS1 and TNKS2, with IC50s of 46 nM and 25 nM, respectively.</p>Fórmula:C25H16ClN7O3SPureza:97.63% - 98.17%Cor e Forma:SolidPeso molecular:529.96Trabectedin
CAS:<p>Trabectedin (Ecteinascidin 743) has potent antitumor activity and the potential for soft tissue sarcoma and ovarian cancer research.</p>Fórmula:C39H43N3O11SPureza:≥98%Cor e Forma:SolidPeso molecular:761.84Niraparib tosylate monohyrate
CAS:Niraparib (MK-4827), a PARP inhibitor, boosts DNA breaks to trigger genomic instability and apoptosis, offering anti-cancer effects.Fórmula:C26H30N4O5SPureza:97.7% - 98.41%Cor e Forma:SolidPeso molecular:510.61Isosteviol
CAS:<p>Isosteviol is a natural sweetener with anti-inflammatory, anti-tumor, glucose-lowering, and other health benefits.</p>Fórmula:C20H30O3Pureza:99.72% - 99.97%Cor e Forma:SolidPeso molecular:318.45SW044248
CAS:<p>SW044248 is a noncanonical Top1 inhibitor. It has selective toxicity for NSCLC cells.</p>Fórmula:C22H23N5O2SPureza:99.56% - 99.87%Cor e Forma:SolidPeso molecular:421.52CM-272
CAS:<p>CM-272 is a dual G9a/DNA methyltransferases (DNMTs) inhibitor.</p>Fórmula:C28H38N4O3Pureza:97.83%Cor e Forma:SolidPeso molecular:478.63LY294002
CAS:<p>LY294002 (SF 1101) is a broad-spectrum inhibitor of PI3K, inhibiting PI3Kα, PI3Kδ, and PI3Kβ (IC50=0.5/0.57/0.97 μM).</p>Fórmula:C19H17NO3Pureza:98% - 99.96%Cor e Forma:Pale Yellow SolidPeso molecular:307.34Torin 2
CAS:<p>Torin 2: mTOR inhibitor, IC50=0.25 nM, 800x more selective than PI3K, with EC50=28/35/118 nM for ATM/ATR/DNA-PK.</p>Fórmula:C24H15F3N4OPureza:98.31% - 99.32%Cor e Forma:SolidPeso molecular:432.4Cardioxane
CAS:<p>Cardioxane (ADR-529) is a cardio-protective drug.</p>Fórmula:C11H16N4O4·HClPureza:98.08%Cor e Forma:SolidPeso molecular:304.73Adefovir
CAS:<p>Adefovir: acyclic nucleoside phosphonate, reverse transcriptase inhibitor for hepatitis B and herpes treatment.</p>Fórmula:C8H12N5O4PPureza:99.56%Cor e Forma:White To Off-White PowderPeso molecular:273.19PJ34 hydrochloride
CAS:<p>PJ34 hydrochloride (PJ34 HCl) is a potent specific inhibitor of PARPl/2.</p>Fórmula:C17H18ClN3O2Pureza:98.87% - ≥95%Cor e Forma:SolidPeso molecular:331.8SRT 2104
CAS:<p>SRT 2104 (GSK2245840) is a selective and brain-permeable SIRT1 activator.</p>Fórmula:C26H24N6O2S2Pureza:98.34% - 99.82%Cor e Forma:SolidPeso molecular:516.64Leniolisib
CAS:<p>Leniolisib (CDZ173) (CDZ173) is a potent and selective PI3Kδ inhibitor (IC50: 11 nM).</p>Fórmula:C21H25F3N6O2Pureza:99.88%Cor e Forma:SolidPeso molecular:450.46Palifosfamide
CAS:<p>Palifosfamide lysine (ZIO-201) stable, effective vs. sarcomas in vitro. IC50: 2.25-6.75 μM, except OS222 at 31.5 μM.</p>Fórmula:C4H11Cl2N2O2PPureza:99.72%Cor e Forma:SolidPeso molecular:221.02360A
CAS:<p>360A is a stabilizing G-Quadruplex ligand, and also inhibits telomerase activity for telomerase in TRAP-G4 assay(IC50 : 300 nM).</p>Fórmula:C27H23N5O2Pureza:98.68%Cor e Forma:SolidPeso molecular:449.5Lomeguatrib
CAS:<p>Lomeguatrib (PaTrin-2), a modified guanine base, inhibits the activity of DNA repair protein O(6)-alkylguanine-DNA alkyltransferase (MGMT) .</p>Fórmula:C10H8BrN5OSPureza:99.26% - >99.99%Cor e Forma:SolidPeso molecular:326.17Nexturastat A
CAS:<p>Nexturastat A is an effective and specific HDAC6 inhibitor (IC50: 5 nM). Its selectivity is >190-fold than other HDACs.</p>Fórmula:C19H23N3O3Pureza:99.40% - 99.57%Cor e Forma:SolidPeso molecular:341.4ETP-45658
CAS:<p>ETP-45658 (ETP45658) is a PI 3-kinase inhibitor (IC50 values are 22, 30, 129 and 710 nM for PI 3-Kα, PI 3-Kδ, PI 3-Kβ and PI 3-Kγ respectively).</p>Fórmula:C16H17N5O2Pureza:99.14%Cor e Forma:SolidPeso molecular:311.34Dactolisib
CAS:<p>Dactolisib (BEZ235) is an orally bioavailable inhibitor of PI3K and mTOR (IC50s: 4 nM/5 nM/7 nM/75 nM, and 20.7 nM for p110α/p110γ/p110δ/p110β and mTOR).</p>Fórmula:C30H23N5OPureza:97.64% - 99.85%Cor e Forma:SolidPeso molecular:469.54Pimelic diphenylamide 106
CAS:<p>Pimelic diphenylamide 106 (RGFA-8) is a slow, tight-binding inhibitor of class I HDAC, showing no activity against class II HDACs.</p>Fórmula:C20H25N3O2Pureza:95.25% - 99.28%Cor e Forma:SolidPeso molecular:339.43TMP269
CAS:<p>TMP269: Class IIa HDAC inhibitor; HDAC4 IC50=157 nM, HDAC5 IC50=97 nM, HDAC7 IC50=43 nM, HDAC9 IC50=23 nM.</p>Fórmula:C25H21F3N4O3SPureza:98% - 99.72%Cor e Forma:SolidPeso molecular:514.52Amonafide
CAS:<p>Amonafide (NSC-308847, AS1413) causes DNA breaks via topoisomerase II, not topoisomerase I.</p>Fórmula:C16H17N3O2Pureza:99.39%Cor e Forma:SolidPeso molecular:283.33A-966492
CAS:<p>A-96649 is a new-type and effective inhibitor. The Ki of A-966492 for PARP1 and PARP2 is 1 nM and 1.5 nM, respectively.</p>Fórmula:C18H17FN4OPureza:98.53% - 99.27%Cor e Forma:SolidPeso molecular:324.356-AZATHYMINE
CAS:<p>6-azathymine inhibits D-3-aminoisobutyrate-pyruvate aminotransferase; 6-azauracil competes with beta-alanine, uncompetitive with pyruvic acid, Ki ~8.9 mM.</p>Fórmula:C4H5N3O2Pureza:99.47%Cor e Forma:SolidPeso molecular:127.1ACY-775
CAS:<p>ACY-775 is an effective and specific inhibitor of HDAC6 (IC50: 7.5 nM).</p>Fórmula:C17H19FN4O2Pureza:97.67% - 98.83%Cor e Forma:SolidPeso molecular:330.36Satraplatin
CAS:<p>Satraplatin (BMS182751) is an orally available antineoplastic platinum(IV) complex.Satraplatin has a favorable toxicity profile and appears to have clinical</p>Fórmula:C10H22Cl2N2O4PtPureza:98.25%Cor e Forma:SolidPeso molecular:500.28CRT0044876
CAS:<p>CRT0044876 (7-NO2-ICA) is a potent and selective APE1 inhibitor with IC50 of ~3 μM.</p>Fórmula:C9H6N2O4Pureza:98.27% - 98.98%Cor e Forma:Brown PowderPeso molecular:206.15azd1390
CAS:<p>AZD1390: Potent ATM inhibitor (IC50: 0.78 nM), >10,000-fold selectivity vs. PIKK enzymes.</p>Fórmula:C27H32FN5O2Pureza:97.41% - 99.72%Cor e Forma:SolidPeso molecular:477.57RGFP966
CAS:<p>RGFP966 is an HDAC3 inhibitor (IC50: 0.08 μM) and does not affect other HDACs at concentrations up to 15 μM.</p>Fórmula:C21H19FN4OPureza:99.2% - 99.88%Cor e Forma:SolidPeso molecular:362.4RG2833
CAS:<p>RG2833 (RGFP109) (RGFP109), a brain-penetrant HDAC inhibitor, is with IC50 of 60 nM and 50 nM for HDAC1 and HDAC3, respectively.</p>Fórmula:C20H25N3O2Pureza:99% - 99.50%Cor e Forma:SolidPeso molecular:339.433,4-Dicaffeoylquinic acid
CAS:<p>3,4-Dicaffeoylquinic acid (Isochlorogenic acid B) has antioxidant activity.</p>Fórmula:C25H24O12Pureza:96.33% - 98.82%Cor e Forma:SolidPeso molecular:516.45Seclidemstat
CAS:<p>Seclidemstat (SP-2577) is an effective LSD1 inhibitor, with a mean IC50 of 127 nM.</p>Fórmula:C20H23ClN4O4SPureza:98.28% - 99.76%Cor e Forma:SolidPeso molecular:450.94Veliparib dihydrochloride
CAS:<p>Veliparib dihydrochloride (ABT-888 dihydrochloride) is a potent inhibitor of PARP1 and PARP2 with Ki of 5.2 nM and 2.9 nM in cell-free assays, respectively.</p>Fórmula:C13H18Cl2N4OPureza:98% - 99.81%Cor e Forma:SolidPeso molecular:317.21Prexasertib dihydrochloride
CAS:<p>Prexasertib dihydrochloride (LY2606368) inhibits CHK1 (Ki: 0.9 nM); IC50: CHK2 8 nM, RSK 9 nM.</p>Fórmula:C18H21Cl2N7O2Pureza:98.46% - 99.82%Cor e Forma:SolidPeso molecular:438.316-Thioguanine
CAS:<p>6-Thioguanine (2-Amino-6-purinethiol) is an antineoplastic compound which also has antimetabolite action. The drug is used in the therapy of acute leukemia.</p>Fórmula:C5H5N5SPureza:98.34% - >99.99%Cor e Forma:Odorless Or Almost Odorless Pale Yellow Crystalline PowderPeso molecular:167.19SIS17
CAS:<p>SIS17: Potent, selective HDAC11 inhibitor (IC50: 0.83 μM), blocks serine hydroxymethyl transferase 2 demyristoylation, spares other HDACs.</p>Fórmula:C21H38N2OSPureza:98.22%Cor e Forma:SolidPeso molecular:366.6CC-115
CAS:<p>CC-115 is a inhibitor of mTOR/DNA-PK (IC50= 21/ 13 nM).</p>Fórmula:C16H16N8OPureza:86.79% - 99.01%Cor e Forma:SolidPeso molecular:336.35SRT 1460
CAS:<p>SRT 1460 is a SIRT1 activator.</p>Fórmula:C26H29N5O4SPureza:98.25%Cor e Forma:SolidPeso molecular:507.6Venadaparib
CAS:<p>Venadaparib, a PARP inhibitor (IC50: 1.4/1.0 nM for PARP1/2), is orally active, selective, not affecting PARP-5, used in tumor studies.</p>Fórmula:C23H23FN4O2Pureza:99.86%Cor e Forma:SolidPeso molecular:406.45Ochromycinone
CAS:<p>Ochromycinone (STA 21) is a selective STAT3 inhibitor.</p>Fórmula:C19H14O4Pureza:99.21%Cor e Forma:SolidPeso molecular:306.315-Methyl-2'-deoxycytidine
CAS:<p>5-Methyl-2'-deoxycytidine (5MedCyd) is a pyrimidine nucleoside that when incorporated into single-stranded DNA can act in cis to signal de novo.</p>Fórmula:C10H15N3O4Pureza:99.18% - 99.69%Cor e Forma:SolidPeso molecular:241.245-Fluoro-2'-deoxycytidine
CAS:<p>5-Fluoro-2'-deoxycytidine (2'-DEOXY-5-FLUOROCYTIDINE) is an inhibitor of DNA methyltransferase (DNMT) .</p>Fórmula:C9H12FN3O4Pureza:97.91%Cor e Forma:Fine White PowderPeso molecular:245.21Bimolane
CAS:<p>Bimolane is a topoisomerase II inhibitor.</p>Fórmula:C20H32N6O6Pureza:99.13% - 99.29%Cor e Forma:SolidPeso molecular:452.5Amsacrine hydrochloride
CAS:<p>Amsacrine hydrochloride (acridinyl anisidide hydrochloride) is topoisomerase II inhibitor , is used in the treatment of acute myelogenous leukemia.</p>Fórmula:C21H20ClN3O3SPureza:99.05% - 99.92%Cor e Forma:SolidPeso molecular:429.92Levofloxacin
CAS:<p>Levofloxacin ((-)-Ofloxacin) is a synthetic fluoroquinolone antibiotic that prevents DNA replication. Cost-effective and quality-assured.</p>Fórmula:C18H20FN3O4Pureza:98.14% - 99.80%Cor e Forma:Off-White To Yellow CrystalsPeso molecular:361.37ACY-738
CAS:<p>ACY-738 demonstrates inhibitory activity against recombinant HDAC6 (IC50: 1.7 nM), with respective average selectivity over class I HDACs being 100-fold.</p>Fórmula:C14H14N4O2Pureza:98.85% - 99.89%Cor e Forma:SolidPeso molecular:270.29YU238259
CAS:<p>YU238259 is a novel inhibitor of homology-dependent DNA repair(HDR), but does not inhibit non-homologous end-joining (NHEJ), in cell-based GFP reporter assays.</p>Fórmula:C22H22ClN3O4SPureza:99.28% - 99.56%Cor e Forma:SolidPeso molecular:459.95GeA-69
CAS:<p>GeA-69 (GeA69) is a selective and allosteric PARP14 macrodomain 2 (MD2) inhibitor (Kd: 0.86 μM in ITC assays).</p>Fórmula:C20H16N2OPureza:99.85%Cor e Forma:SolidPeso molecular:300.35Talazoparib
CAS:<p>Talazoparib (LT-673) is a new-type PARP inhibitor (IC50: 0.58 nM), It similarly binds to PARP1/2 (Kis: 1.2/0.85 nM).</p>Fórmula:C19H14F2N6OPureza:97.02% - 99.92%Cor e Forma:SolidPeso molecular:380.35Tunicamycin
CAS:<p>Tunicamycin is a mixture of antibiotics that inhibit N-linked glycosylation by blocking GlcNAc phosphotransferase (GPT).</p>Fórmula:C39H64N4O16Pureza:98.77%Cor e Forma:White Crystalline SolidPeso molecular:844.94 (n=10)LY-294002 hydrochloride
CAS:<p>LY-294002 HCl (NSC 697286) is a stable PI3K inhibitor (IC50: 0.5-0.97 µM) and prevents autophagosome formation.</p>Fórmula:C19H17NO3·HClPureza:99.95%Cor e Forma:SolidPeso molecular:343.81HDAC8-IN-1
CAS:<p>MDK-7933 (HDAC8-IN-1) is a HDAC8 inhibitor with an IC50 of 27.2 nM in cancer cell lines.</p>Fórmula:C22H19NO3Pureza:97.13% - 99.19%Cor e Forma:SolidPeso molecular:345.39Belinostat
CAS:<p>Belinostat (PXD101) is an inhibitor of hydroxamic acid-type histone deacetylase (HDAC, IC50 of 27 nM in HeLa cell extracts),and with antineoplastic activity.</p>Fórmula:C15H14N2O4SPureza:99.75% - >99.99%Cor e Forma:SolidPeso molecular:318.35Veliparib
CAS:<p>Veliparib (ABT-888) (ABT-888) is an orally bioavailable inhibitor of PARP (Kis: 5.2/2.9 nM for PARP1/2). It enhances apoptosis and autophagy.</p>Fórmula:C13H16N4OPureza:98.66% - 99%Cor e Forma:SolidPeso molecular:244.29SF2523
CAS:<p>SF2523 is a highly selective and potent inhibitor.</p>Fórmula:C19H17NO5SPureza:99.1% - 99.51%Cor e Forma:SolidPeso molecular:371.41SGI-1027
CAS:<p>SGI-1027 (DNA Methyltransferase Inhibitor II) is an effective and selective inhibitor of DNA methyltransferase (DNMT).</p>Fórmula:C27H23N7OPureza:99.45% - 99.78%Cor e Forma:SolidPeso molecular:461.523-Methoxybenzamide
CAS:<p>3-Methoxybenzamide (3-MBA) is a competitive inhibitor of poly(ADP-ribose) synthetase.</p>Fórmula:C8H9NO2Pureza:98.52%Cor e Forma:SolidPeso molecular:151.16HDAC-IN-7
CAS:<p>HDAC-IN-7 (HBI-8000) (Chidamide impurity) is an impurity of Chidamide.</p>Fórmula:C22H19FN4O2Pureza:97.64% - 98.45%Cor e Forma:SolidPeso molecular:390.41Pirarubicin
CAS:<p>Pirarubicin (Theprubicin), an anthracycline antibiotic, inhibits DNA/RNA synthesis and is used as an antineoplastic.</p>Fórmula:C32H37NO12Pureza:97.80% - 99.15%Cor e Forma:Red Crystalline PowderPeso molecular:627.64Potassium acetate
CAS:<p>Potassium acetate (Diuretic salt) with antibacterial and antifungal properties.</p>Fórmula:C2H3KO2Pureza:≥98%Cor e Forma:Colorless Lustrous Rapidly Deliquescent Crystals Or White Crystal Powder Or Flakes Solid Repidly Deliquescent Crystals Or White Crystal Powder Or FlakesPeso molecular:98.14TAS-103 dihydrochloride
CAS:<p>TAS-103 dihydrochloride (BMS-247615 dihydrochloride) is a novel anticancer agent targeting both topoisomerase (Topo) I and Topo II.</p>Fórmula:C20H21Cl2N3O2Pureza:97.78%Cor e Forma:SolidPeso molecular:406.31KU-0060648
CAS:<p>KU-0060648 is a dual inhibitor of DNA-PK and PI3Kα, PI3Kβ, PI3Kδ with IC50 of 8.6 nM and 4 nM, 0.5 nM, 0.1 nM respectively, less inhibition of PI3Kγ.</p>Fórmula:C33H34N4O4SPureza:98.75%Cor e Forma:SolidPeso molecular:582.71Hypericin
CAS:<p>Hypericin (Cyclosan) is a natural anthraquinone compound. Hypericin exhibits antimicrobial, antiviral, antitumor, and antidepressant effects. Cost-effective and quality-assured.</p>Fórmula:C30H16O8Pureza:99.05% - ≥98%Cor e Forma:Red-Coloured Anthraquinone-DerivativePeso molecular:504.44PIK-75
CAS:<p>PIK-75, a DNA-PK and PI3K inhibitor, suppresses DNA-PK(IC50=2 nM), p110α(IC50=5.8 nM) and p110γ(IC50=76 nM).</p>Fórmula:C16H14BrN5O4SPureza:98.52% - >99.99%Cor e Forma:SolidPeso molecular:452.28RG108
CAS:<p>RG108 (N-Phthalyl-L-tryptophan) is an DNA methyltransferase inhibitor(IC50=115 nM).</p>Fórmula:C19H14N2O4Pureza:98% - 99.43%Cor e Forma:SolidPeso molecular:334.33ETP-46464
CAS:<p>ETP-46464 is an effective and specific ATR inhibitor (IC50: 25 nM).</p>Fórmula:C30H22N4O2Pureza:97.76%Cor e Forma:SolidPeso molecular:470.52Brincidofovir
CAS:<p>Brincidofovir (HDP-CDV) is an orally active, lipophilic form of cidofovir.</p>Fórmula:C27H52N3O7PPureza:98% - 99.62%Cor e Forma:SolidPeso molecular:561.69Neobavaisoflavone
CAS:<p>Neobavaisoflavone: DNA polymerase inhibitor, potential for treating bone loss, anti-inflammatory, reduces ROS, RNS, cytokines in macrophages.</p>Fórmula:C20H18O4Pureza:99.31% - 99.87%Cor e Forma:SolidPeso molecular:322.35CHDI-390576
CAS:<p>CHDI-390576 is an HDAC inhibitor that inhibits class IIa HDAC 4, HDAC 5, HDAC 7, and HDAC 9, and can be used in cancer research.</p>Fórmula:C19H13F4N3O2Pureza:98.92% - 99.03%Cor e Forma:SolidPeso molecular:391.32MDL-800
CAS:<p>MDL-800 is a SIRT6 modulator with antitumor activity for the study of hepatocellular carcinoma and non-small cell lung cancer.</p>Fórmula:C21H16BrCl2FN2O6S2Pureza:99.95% - 99.96%Cor e Forma:SolidPeso molecular:626.3Talazoparib tosylate
CAS:<p>PF-3882845 is an MR antagonist that binds to the progesterone receptor (PR) and is used in the study of endocrine disorders and urogenital disorders.</p>Fórmula:C26H22F2N6O4SPureza:99.79%Cor e Forma:SolidPeso molecular:552.55CBHcy
CAS:<p>CBHcy, a dual substrate analog, is a specific BHMT inhibitor that may induce cysteinemia.</p>Fórmula:C9H17NO4SPureza:>99.99% - >99.99%Cor e Forma:SolidPeso molecular:235.3IndiMitecan
CAS:<p>IndiMitecan (LMP776) is an inhibitor of topoisomerase I (Top1) with anticancer activities [1].</p>Fórmula:C25H21N3O6Pureza:98.53%Cor e Forma:SoildPeso molecular:459.45Mouse PARP2(Poly [ADP-ribose] polymerase 2) ELISA Kit
<p>The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse PARP2. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse PARP2. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Mouse PARP2, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Mouse PARP2 in the samples is then determined by comparing the OD of the samples to the standard curve.</p>Cor e Forma:Colourless TransparentliquidRGFP966 (E-isomer)
CAS:<p>RGFP966 is an HDAC3 inhibitor with IC50 of 0.08 μM, exhibits > 200-fold selectivity over other HDAC.</p>Fórmula:C21H19FN4OPureza:99.93%Cor e Forma:SolidPeso molecular:362.4Semustine
CAS:<p>Semustine, a DNA alkylating agent, is a cancer chemotherapy compound that is nephrotoxic in patients with malignant melanoma receiving adjuvant chemotherapy for</p>Fórmula:C10H18ClN3O2Pureza:99.70%Cor e Forma:Light Yellow PowderPeso molecular:247.72Exatecan
CAS:<p>Exatecan (DX-8951f) is a DNA topoisomerase I (TOP1) inhibitor with an IC50 value of 2.2 μM (0.975 μg/mL).Exatecan has antitumor activity and may be used in</p>Fórmula:C24H22FN3O4Pureza:99.64% - 99.84%Cor e Forma:SolidPeso molecular:435.45Cyclophosphamide-d4
CAS:<p>Cyclophosphamide-d4 is a deuterated compound of Cyclophosphamide. Cyclophosphamide has a CAS number of 50-18-0. Cyclophosphamide is an alkylating agent used in the treatment of several forms of cancer including leukemias, lymphomas and breast cancer.</p>Fórmula:C7H11D4Cl2N2O2PCor e Forma:SolidPeso molecular:265.11Mirin
CAS:<p>Mirin is a Mre11-Rad50-Nbs1 (MRN) complex inhibitor and also inhibits Mre11-associated exonuclease activity.Mirin induces cell cycle arrest in G1 phase.</p>Fórmula:C10H8N2O2SPureza:99.24%Cor e Forma:SolidPeso molecular:220.25ART0380
CAS:<p>ART0380 is a potent, antitumor, selective, orally available, ATP-competitive ATR kinase inhibitor for the study of ataxia telangiectasia mutated (ATM) cancer.</p>Fórmula:C18H24N6O2SPureza:99.06% - >99.99%Cor e Forma:SolidPeso molecular:388.49PNU-159682
CAS:<p>PNU-159682 is a highly effective metabolite of the anthracycline nemorubicin.</p>Fórmula:C32H35NO13Pureza:98.24%Cor e Forma:SolidPeso molecular:641.62BRD 4354 ditrifluoroacetate
<p>BRD 4354 (ditrifluoroacetate) is a moderately potent inhibitor of HDAC5 and HDAC9 (IC50s: 0.85 and 1.88 μM).</p>Fórmula:C25H25ClF6N4O5Pureza:98%Cor e Forma:SolidPeso molecular:610.93MY-1B
CAS:<p>MY-1B is a nitrogen-substituted butenamide stereoprobe that blocks stereoselective enrichment of NSUN2, binding selectively to the C271 of NSUN2.</p>Fórmula:C22H18BrN3O2Pureza:99.81% - >99.99%Cor e Forma:SoildPeso molecular:436.37-Methyladenine
CAS:<p>7-Methyladenine (NSC-7857) can be used as a marker of exposure to exogenous and carcinogenic methylating agents.</p>Fórmula:C6H7N5Pureza:99.90%Cor e Forma:SolidPeso molecular:149.15Elaidyl-sulfamide
CAS:<p>Elaidyl-sulfamide is a sulfamoyl analogue of oleoylethanolamide (OEA). ES is a lipid mediator of satiety that acts through the PPARα.</p>Fórmula:C18H38N2O2SPureza:98%Cor e Forma:SolidPeso molecular:346.57A 20832
CAS:<p>A-20832 blocks strand cleavage in resolvase-driven recombination; doesn't prevent resolvase-res binding or synapse formation, only binds at res site I.</p>Fórmula:C10H14Cl2O3Pureza:98%Cor e Forma:SolidPeso molecular:253.12GSK-7227
CAS:<p>GSK-7227 is a novel PPARδ partial agonist that upregulates target genes in muscle cells, indicating its potential role in modulating muscle metabolism and energy.</p>Fórmula:C25H22N2O6SPureza:99.17%Cor e Forma:SolidPeso molecular:478.52LMP744
CAS:<p>LMP744 is a DNA intercalator and Topoisomerase I (Top1) inhibitor with antitumor activity.</p>Fórmula:C24H24N2O7Cor e Forma:SolidPeso molecular:452.46A-1062
CAS:<p>A-1062, a resolvase-binding inhibitor, inhibits resolvase binding to the res site.</p>Fórmula:C18H10O6SPureza:98%Cor e Forma:SolidPeso molecular:354.33L-764406
CAS:<p>L-764406 is a partial agonist of human PPAR gamma.</p>Fórmula:C15H11ClN2O2SPureza:98%Cor e Forma:SolidPeso molecular:318.78A 9387
CAS:<p>A 9387 is an inhibitor of resolvase protein.</p>Fórmula:C12H6Br2Cl2O2SCor e Forma:SolidPeso molecular:444.95SIRT2-IN-9
CAS:<p>SIRT2-IN-9: selective SIRT2 inhibitor; IC50=1.3μM; halts MCF-7 cell growth; for cancer study.</p>Fórmula:C21H22N6OS2Pureza:99.5%Cor e Forma:SolidPeso molecular:438.57Lobeglitazone Sulfate
CAS:<p>Lobeglitazone Sulfate (CKD-501) is an anti-inflammatory thiazolidinedione that prevents NLRP3 inflammasome activation and is used in T2DM research.</p>Fórmula:C24H26N4O9S2Pureza:98.69%Cor e Forma:SolidPeso molecular:578.61BVT.13
CAS:<p>BVT.13 is used as a selective PPAR-gamma activator.</p>Fórmula:C18H11Cl2N3O4Cor e Forma:SolidPeso molecular:404.2RSC-133
CAS:<p>promotes the reprogramming of human somatic cells to pluripotent stem cells</p>Fórmula:C18H15N3O2Pureza:98%Cor e Forma:SolidPeso molecular:305.33Aldoxorubicin
CAS:<p>Aldoxorubicin, an albumin-binding prodrug of Doxorubicin, exhibits potent antitumor effects in cancer lines and mouse models.</p>Fórmula:C37H42N4O13Pureza:98%Cor e Forma:SolidPeso molecular:750.75Cas9-IN-3
CAS:<p>Cas9-IN-3 is a potent inhibitor of Cas9 with IC50 of 28 μM. CRISPR/Cas systems have revolutionized gene editing in several species [1].</p>Fórmula:C19H21NOCor e Forma:SolidPeso molecular:279.38Exifone
CAS:<p>Exifone (NSC-680919) is a mixed, nonessential activator of HDAC1 that is capable of binding to both free and substrate-bound enzyme, resulting in an increased</p>Fórmula:C13H10O7Pureza:99.77% - 99.95%Cor e Forma:Yellow SolidPeso molecular:278.21BRD0539
CAS:<p>BRD0539 is a cell-permeable spCas9 inhibitor that blocks the binding of spCas9 to DNA and inhibits Streptococcus pyogenes Cas9 (SpCas9).</p>Fórmula:C25H25FN2O3SPureza:98.03%Cor e Forma:SolidPeso molecular:452.54Guadecitabine
CAS:<p>Guadecitabine is a second-generation DNA methyltransferases inhibitor. It is used for research on acute myeloid leukemia and myelodysplastic syndromes.</p>Fórmula:C18H24N9O10PPureza:98%Cor e Forma:SolidPeso molecular:557.41Naveglitazar racemate
CAS:<p>Naveglitazar racemate is the racemate of Naveglitazar.</p>Fórmula:C25H26O6Pureza:98%Cor e Forma:SolidPeso molecular:422.47Chlornaphazine
CAS:<p>Chlornaphazine is an antineoplastic and has been identified as a human carcinogen.</p>Fórmula:C14H15Cl2NPureza:98%Cor e Forma:Less Plates Or Brown Solid (Ntp 1992) Physical Description Colorless Plates Or Brown Solid (Ntp 1992)Peso molecular:268.18Arazine
CAS:<p>Arazine, a cell-permeable G protein modulator, is an isoprenylcysteine methyltransferase substrate.</p>Fórmula:C20H33NO3SPureza:90%Cor e Forma:SolidPeso molecular:367.55NU/ICRF 500
CAS:<p>NU/ICRF 500 is a novel anthracenyl-amino acid catalytic inhibitor of topoisomerase II.</p>Fórmula:C17H15N3O5Pureza:98%Cor e Forma:SolidPeso molecular:341.32S-Aristeromycinylhomocysteine
CAS:<p>S-Aristeromycinylhomocysteine is an inhibitor of adenosylmethionine decarboxylase.</p>Fórmula:C15H22N6O4SCor e Forma:SolidPeso molecular:382.44GW0072
CAS:<p>GW0072 is a partial agonist of PPARγ.</p>Fórmula:C36H44N2O4SCor e Forma:SolidPeso molecular:600.81PPARγ agonist 3
CAS:<p>PPARγ agonist 3, also known as Compound 18a, is a potent and selective agonist of PPARγ.</p>Fórmula:C24H23N3OCor e Forma:SolidPeso molecular:369.46XR-11576
CAS:XR-11576 is a DNA topoisomerase I and II inhibitor for the treatment of solid tumors.Fórmula:C23H24N4O2Pureza:98%Cor e Forma:SolidPeso molecular:388.46NC182
CAS:<p>NC182 is a topo II inhibitor that shows selective and potent topo II inhibition on the induction of topo II-dependent DNA fragmentation.</p>Fórmula:C24H24N4O5Pureza:98%Cor e Forma:SolidPeso molecular:448.47GW2433
CAS:<p>GW2433 is an agonist of PPAR receptor.</p>Fórmula:C28H28Cl3FN2O4Cor e Forma:SolidPeso molecular:581.89Leurubicin
CAS:<p>Leurubicin is used as a prodrug of doxorubicin.</p>Fórmula:C33H40N2O12Pureza:98.66% - >99.99%Cor e Forma:SolidPeso molecular:656.68ICRF-193
CAS:<p>ICRF-193 is a DNA topoisomerase II inhibitor.</p>Fórmula:C12H18N4O4Cor e Forma:SolidPeso molecular:282.32′-Deoxy-5-nitrocytidine
CAS:<p>2′-Deoxy-5-nitrocytidine is a DNA Methyltransferase inhibitor that can be used for cancer research[1].</p>Fórmula:C9H12N4O6Cor e Forma:SolidPeso molecular:272.21
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