Imunologia e Inflamação
Os inibidores de imunologia e inflamação são compostos que modulam a resposta imunológica e os processos inflamatórios. Esses inibidores são cruciais para estudar os mecanismos de regulação imunológica, autoimunidade e inflamação crônica, bem como para desenvolver tratamentos para doenças inflamatórias, alergias e distúrbios relacionados ao sistema imunológico. Ao direcionar vias-chave no sistema imunológico, esses inibidores podem ajudar a reduzir respostas imunológicas excessivas ou inadequadas. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de alta qualidade para apoiar sua pesquisa em imunologia, inflamação e desenvolvimento terapêutico.
Subcategorias de "Imunologia e Inflamação"
- CCR(136 produtos)
- CXCR(149 produtos)
- Parede celular(5 produtos)
- Receptor IL(112 produtos)
- IκB/IKK(59 produtos)
- LTR(3 produtos)
- MALT(23 produtos)
- MRP(6 produtos)
- NADPH-oxidase(1 produtos)
- NF-κB(443 produtos)
- NOD(18 produtos)
- NOS(62 produtos)
- Nrf2(78 produtos)
- PGE Sintase(31 produtos)
- ROS(69 produtos)
- TGF-beta/Smad(58 produtos)
- TLR(66 produtos)
- Tiorredoxina(12 produtos)
- gp120/CD4(4 produtos)
Exibir 11 mais subcategorias
Foram encontrados 3055 produtos de "Imunologia e Inflamação"
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BCX 1470
CAS:<p>BCX 1470 inhibits the esterolytic activity of factor D and C1s (IC50: 96 nM and 1.6 nM), 3.4- and 200-fold better than that of trypsin, respectively.</p>Fórmula:C14H10N2O2S2Pureza:98%Cor e Forma:SolidPeso molecular:302.37Tin(IV) mesoporphyrin IX dichloride
CAS:<p>Tin(IV) mesoporphyrin IX dichloride (Stannsoporfin) is an effective heme oxygenase (HO) inhibitor used for the treatment of hyperbilirubinemia.</p>Fórmula:C34H36Cl2N4O4SnPureza:99.82%Cor e Forma:SolidPeso molecular:754.29Naproxcinod
CAS:<p>Naproxcinod is a derivative of naproxen, analgesic and anti-inflammatory, a COX-inhibitory nitric oxide donor (CINOD), osteoarthritis and inflammatory.</p>Fórmula:C18H21NO6Cor e Forma:SolidPeso molecular:347.36UC-781
CAS:<p>UC-781, a potent NNRTI, inhibits HIV-1 with a C50 of 5 nM and is stable across pH and temperatures.</p>Fórmula:C17H18ClNO2SPureza:92.17%Cor e Forma:SolidPeso molecular:335.85NED-3238
CAS:<p>NED-3238 is a highly potent inhibitor of arginase I and II (IC50 of 1.3 nM and 8.1 nM, respectively).</p>Fórmula:C17H28BN3O4Pureza:98%Cor e Forma:SolidPeso molecular:349.23AXC-715 trihydrochloride
CAS:<p>AXC-715 trihydrochloride is a TLR7/8 agonist used to make PD-L1 adjuvanted antibody immunocouplings.</p>Fórmula:C18H28Cl3N5Pureza:99.74%Cor e Forma:SolidPeso molecular:420.81Vidarabine phosphate
CAS:Vidarabine phosphate is an adenosine monophosphate analog.Fórmula:C10H14N5O7PPureza:99.75%Cor e Forma:White Crystalline PowderPeso molecular:347.22Xanthine oxidase-IN-6
<p>Xanthine oxidase-IN-6: potent oral mixed-type XOD inhibitor, IC50 1.37 µM, anti-hyperuricemia, renal protection.</p>Fórmula:C29H34N2O15Cor e Forma:SolidPeso molecular:650.58MLT-747
CAS:MLT-747 is an effective and allosteric inhibitor of MALT1. It binds MALT1 in the allosteric Trp580 pocket (IC50: 14 nM).Fórmula:C20H21Cl2N7O3Cor e Forma:SolidPeso molecular:478.33COX-2-IN-11
CAS:<p>COX-2-IN-11 (compound 7b2) is a potent and selective COX-2 inhibitor. COX-2-IN-11 has the potential in inflammation disease research[1].</p>Fórmula:C12H12OS3Cor e Forma:SolidPeso molecular:268.42M62812 free base
CAS:<p>M62812 (free base), a Toll-like receptor 4 (TLR4) signal transduction inhibitor, suppresses activation of endothelial cells and leukocytes and prevents lethal</p>Fórmula:C13H11N3OSCor e Forma:SolidPeso molecular:257.31Safrole oxide
CAS:<p>Safrole oxide inhibits neuronal growth, induces apoptosis, elevates COX-2, IL-8, ROS, promoting endothelial-to-neuron-like cell transdifferentiation.</p>Fórmula:C10H10O3Pureza:100%Cor e Forma:SolidPeso molecular:178.18PNRI-299
CAS:<p>PNRI-299 is a selective inhibitor of AP-1 transcription(IC50 of 20 uM ).</p>Fórmula:C21H15N5O4Pureza:98%Cor e Forma:SolidPeso molecular:401.37Naphazoline
CAS:<p>Naphazoline (Naphcon-a) is a sympathomimetic compound with marked alpha adrenergic activity.</p>Fórmula:C14H14N2Pureza:99.79%Cor e Forma:White Crystalline Powder SolidPeso molecular:210.27CD73-IN-1
CAS:CD73-IN-1 is a CD73 inhibitor with anticancer activity.Fórmula:C18H17N3O4SPureza:99.46% - 99.46%Cor e Forma:SolidPeso molecular:371.41Veledimex (S enantiomer)
CAS:Veledimex S is the oral S enantiomer of a gene therapy promoter activator and CYP3A4/5 inhibitor.Fórmula:C27H38N2O3Pureza:98%Cor e Forma:SolidPeso molecular:438.6COX-2/sEH-IN-1
CAS:<p>COX-2/sEH-IN-1, oral dual inhibitor: COX-2 (IC50=1.24 μM), sEH (IC50=0.40 μM); boosts anti-inflammatory action, cuts heart risk.</p>Fórmula:C23H18F3N5O3SCor e Forma:SolidPeso molecular:501.48Keap1-Nrf2-IN-14
CAS:<p>Keap1-Nrf2-IN-14, a KEAP1-NRF2 inhibitor (IC50: 75 nM, Kd: 24 nM), boosts NRF2 gene expression, antioxidative and anti-inflammatory response.</p>Fórmula:C30H29NO8SCor e Forma:SolidPeso molecular:563.62β-Nor-lapachone
CAS:β-Nor-lapachone is an antibiofilm agent of Candida glabrata.Fórmula:C14H12O3Cor e Forma:SolidPeso molecular:228.24COX-1/2-IN-1
CAS:<p>"COX-1/2-IN-2: Strong dual inhibitor of COX-1 (IC50 = 13.9 μM) and COX-2 (IC50 = 6.4 μM)."</p>Fórmula:C15H10BrClN2OCor e Forma:SolidPeso molecular:349.61Z-VRPR-FMK
CAS:<p>Z-VRPR-FMK: irreversible MALT1 inhibitor, halts growth/invasion of diffused B-cell lymphoma by blocking NF-κB activation and MMP expression.</p>Fórmula:C31H49FN10O6Cor e Forma:SolidPeso molecular:676.78COX-1/2-IN-3
CAS:<p>COX-1/2-IN-3 (Compound 7a) is a dual inhibitor of COX-1 and COX-2. COX-1/2-IN-3 has anti-inflammatory activity with low toxicity [1].</p>Fórmula:C14H8N2O8Cor e Forma:SolidPeso molecular:332.22IFN α-IFNAR-IN-1
CAS:<p>Nonpeptidic IFN-α/IFNAR blocker, halts MVA-triggered BM-pDC IFN-α response; IC50: 2-8 μM.</p>Fórmula:C18H17NSPureza:98%Cor e Forma:SolidPeso molecular:279.4COX-2-IN-23
CAS:<p>COX-2-IN-23 selectively inhibits COX-2 (IC50=0.28μM), weakly affects COX-1 (IC50=20.14μM), and has anti-inflammatory and low ulcerogenic properties.</p>Fórmula:C24H25N5O3S2Cor e Forma:SolidPeso molecular:495.62IRAK4-IN-13
CAS:<p>IRAK4-IN-13 (compound 21) is a potent IRAK4 inhibitor, IC50 0.6 nM, with high HLM clearance at 96 μL/min/mg.</p>Fórmula:C24H27N9OCor e Forma:SolidPeso molecular:457.53OXSI-2
CAS:<p>OXSI-2 (Syk Inhibitor) is an inhibitor of Syk with an EC50 of 313 nM and an IC50 of 14 nM.</p>Fórmula:C18H15N3O3SPureza:98%Cor e Forma:Dark Orange SolidPeso molecular:353.39PPM-18
CAS:<p>PPM-18 (NSC 73233), a potent anti-inflammatory, inhibits iNOS and NF-κB binding; also suppresses bladder cancer cell growth.</p>Fórmula:C17H11NO3Cor e Forma:SolidPeso molecular:277.27Carpro-AM1
CAS:<p>Carpro-AM1, dual FAAH/COX inhibitor, IC50: 94 nM.</p>Fórmula:C21H18ClN3OCor e Forma:SolidPeso molecular:363.84ASP-6537
CAS:ASP-6537 is a selective and reversible inhibitor of cyclooxygenase-1.Fórmula:C17H17N3O3Pureza:98%Cor e Forma:SolidPeso molecular:311.34COX-2-IN-24
CAS:<p>COX-2-IN-24 is an orally active COX-2 inhibitor (IC50: 0.17 μM) with anti-inflammatory and hypo-ulcerogenic effects.</p>Fórmula:C24H24BrN5O3S2Cor e Forma:SolidPeso molecular:574.51CU-32
CAS:<p>CU-32 is a cGAS inhibitor with IC50=0.45 μM, blocks DNA-stimulated IFN-β production, and is selective over RIG-I-MAVS and TLRs pathways.</p>Fórmula:C11H10IN5O2Cor e Forma:SolidPeso molecular:371.1312(R)-HETE
CAS:<p>12(R)-HETE made in invertebrates by lipoxygenation, in mammals by 12(R)-LOs/CYP450. Mainly proinflammatory, attracts leukocytes, reduces rabbit eye pressure.</p>Fórmula:C20H32O3Cor e Forma:SolidPeso molecular:320.471-Dehydro-[10]-gingerdione
CAS:<p>1-Dehydro-[10]-gingerdione blocks IKKβ, curbs IκBα phosphorylation, halts NF-κB activity, and aids inflammation research.</p>Fórmula:C21H30O4Cor e Forma:SolidPeso molecular:346.46L-NMMA acetate
CAS:L-NMMA acetate inhibits all NOS types (nNOS, eNOS, iNOS); Ki: 0.18, 0.4, 6 µM respectively.Fórmula:C9H20N4O4Pureza:99.72% - 99.8%Cor e Forma:White To Off-White SolidPeso molecular:248.28(R,1R)-Tenofovir amibufenamide
CAS:<p>(R,1R)-Tenofovir amibufenamide ((R,1R)-HS-10234) can be used as a Tenofovir prodrug, which can be taken orally and has antiviral activity.</p>Fórmula:C22H31N6O5PPureza:98.79% - 99.02%Cor e Forma:SolidPeso molecular:490.49COX-2-IN-19
CAS:<p>COX-2-IN-19, a potent COX-2 inhibitor, IC50 of 1.76 μM, has strong anti-inflammatory effects in vivo.</p>Fórmula:C18H18N4O2SCor e Forma:SolidPeso molecular:354.43CAY10589
CAS:<p>CAY10589 is an mPGES-1 inhibitor.</p>Fórmula:C25H28ClN3O2SCor e Forma:SolidPeso molecular:470.03DMX-129
CAS:<p>DMX-129 is a chemical compound acting as an inhibitor for both ΙΚΚε and TBK-1, demonstrating efficacy with IC50 values of below 30 nM for each [1].</p>Fórmula:C19H17FN8Cor e Forma:SolidPeso molecular:376.39COX-2/5-LOX-IN-2
CAS:<p>COX-2/5-LOX-IN-2, a benzothiophen derivative, inhibits COX-1, COX-2, 5-LOX with IC50s of 5.40, 0.01, 1.78 μM. More effective than Celecoxib, Indomethacin.</p>Fórmula:C18H13N3O4S2Cor e Forma:SolidPeso molecular:399.44COX-2-IN-17
CAS:<p>COX-2-IN-17 is a potent, blood-brain barrier permeable COX-2 (cyclooxygenase-2) inhibitor (IC50: 0.02 μM) with anti-inflammatory and analgesic activity.</p>Fórmula:C20H23ClN6O2Cor e Forma:SolidPeso molecular:414.89PT4
CAS:<p>PT4: treats CL, disrupts parasite mitochondria, kills Leishmania spp., IC50- L. amazonensis 125.18 μM, L. braziliensis 233.18 μM, anti-inflammatory.</p>Fórmula:C18H14N4O2Cor e Forma:SolidPeso molecular:318.33P2X7-IN-2
CAS:<p>P2X7-IN-2 is a P2X7 receptor blocker, halts IL-Iβ release (IC50: 0.01 nM), researched for autoimmunity and heart issues.</p>Fórmula:C22H21F4N3O2Cor e Forma:SolidPeso molecular:435.41IT-901
CAS:<p>IT-901: Oral NF-κB c-Rel inhibitor, IC50 0.1 µM. Blocks c-Rel/DNA binding, IC50 3 µM. Antitumor naphthalene derivative for lymphoma/myeloma therapy.</p>Fórmula:C17H14N2O4SPureza:98.06%Cor e Forma:SolidPeso molecular:342.37Piroxicam cinnamate
CAS:<p>Cinnoxicam is a COX inhibitor used for bone/joint inflammation, rheumatic issues, and varicocele-related oligospermia.</p>Fórmula:C24H19N3O5SCor e Forma:SolidPeso molecular:461.49Keap1-Nrf2-IN-12
CAS:<p>eap1-Nrf2-IN-12 is a potent inhibitor of Keap1-Nrf2 (IC50: 2.30 μM). eap1-Nrf2-IN-12 is metabolically stable in human liver microsomes.</p>Fórmula:C26H28N2O10S2Cor e Forma:SolidPeso molecular:592.64Ophthalmic acid
CAS:<p>Ophthalmic acid is a glutathione analog in which cysteine is substituted by L-aminobutyrate.</p>Fórmula:C11H19N3O6Cor e Forma:SolidPeso molecular:289.29Avanafil dibesylate
CAS:<p>Avanafil dibesylate is a PDE5 inhibitor.</p>Fórmula:C35H38ClN7O9S2Cor e Forma:SolidPeso molecular:800.3APHS
CAS:<p>APHS is a cyclooxygenase-2 (COX-2) inhibitor with anti-inflammatory action. It also more potent than aspirin in the inhibition of COX-1.</p>Fórmula:C15H18O2SCor e Forma:SolidPeso molecular:262.37CAY10575
CAS:<p>CAY10575 (IKK2-IN-3) is a potent IKK2 inhibitor with potential anti-inflammatory activity for the study of inflammatory and endocrine diseases.</p>Fórmula:C22H21N3O6S2Cor e Forma:SolidPeso molecular:487.55Feprazone
CAS:<p>Feprazone (DA-2370) possesses anti-inflammatory and antiadipogenic properties. Feprazone can be used in studies about the treatment of joint and muscular pain.</p>Fórmula:C20H20N2O2Pureza:99.6% - 99.89%Cor e Forma:SolidPeso molecular:320.39PD 127443
CAS:<p>PD 127443 is a Leukotriene B4 antagonist, it is also a dual inhibitor of cyclooxygenase and 5-lipoxygenase.</p>Fórmula:C20H28N2OCor e Forma:SolidPeso molecular:312.45NLRP3-IN-16
CAS:<p>NLRP3-IN-16: potent NLRP3 inflammasome inhibitor; IC50=0.065μM; curbs IL-1β; used in inflammation studies.</p>Fórmula:C25H25NO5Pureza:98%Cor e Forma:SolidPeso molecular:419.478A8
CAS:<p>8A8 is a potent NO inhibitor with proinflammatory factor properties, exhibiting an IC50 of 4.7 μM.</p>Fórmula:C36H37BrClN5O9Pureza:98%Cor e Forma:SolidPeso molecular:799.06NXPZ-2
CAS:<p>NXPZ-2, an oral Keap1-Nrf2 PPI inhibitor (Ki: 95 nM, EC50: 120-170 nM), may improve cognition and neuron health in AD.</p>Fórmula:C27H27N5O7S2Cor e Forma:SolidPeso molecular:597.66Ferric citrate
CAS:<p>Ferric citrate as a source of iron used in cell culture applications can provide iron with a less toxic form compared to free iron salts.</p>Fórmula:C6H8FeO7Cor e Forma:Limit Its Spread To The Environment It Is Used In Medicine In Making Blueprints And As A FeedPeso molecular:247.968IMD-biphenylB
CAS:<p>IMD-biphenylB: Potent NF-κB inhibitor, curbs tumor growth with low inflammation and toxicity.</p>Fórmula:C35H33N5O3Pureza:98%Cor e Forma:SolidPeso molecular:571.6710-Cl-BBQ
CAS:<p>10-Cl-BBQ is a ligand of aryl hydrocarbon receptor (AhR).</p>Fórmula:C18H9ClN2OCor e Forma:SolidPeso molecular:304.73IKK2-IN-4
CAS:<p>IKK2-IN-4(IKK2 Inhibitor VI) is a highly potent IKK-2 inhibitor with an IC50 value of 25 nM. IKK2-IN-4 inhibited the production of TNF-α in PBMC induced by LPS.</p>Fórmula:C12H11N3O2SPureza:>99.99%Cor e Forma:SolidPeso molecular:261.3Leptospermone
CAS:<p>Leptospermone is an essential oil from Leptospermum scoparium (manuka oil).</p>Fórmula:C15H22O4Cor e Forma:SolidPeso molecular:266.33STING agonist-30
CAS:<p>STING agonist-30 is a STING agonist that stimulates STING-dependent immune activation and inhibits HSV, rotavirus and SARS-CoV-2.</p>Fórmula:C15H16N4O8Pureza:98.80%Cor e Forma:SolidPeso molecular:380.31TFC-007
CAS:TFC-007 is an H-PGDS inhibitor, reducing inflammation, useful for studying guinea pig allergic rhinitis induced by cedar pollen.Fórmula:C27H29N5O4Pureza:98.07%Cor e Forma:SolidPeso molecular:487.55Keap1-Nrf2-IN-11
CAS:<p>Keap1-Nrf2-IN-11 (6k) inhibits Keap1-Nrf2, KD 0.21 nM; reduces ROS, NO, TNF-α; aids anti-inflammatory research.</p>Fórmula:C36H43N7O8S2Cor e Forma:SolidPeso molecular:765.9iNOs-IN-3
CAS:<p>iNOs-IN-3: oral iNOS inhibitor, IC50 = 3.342 μM, anti-inflammatory, for LPS-induced ALI study.</p>Fórmula:C27H24N2O5SCor e Forma:SolidPeso molecular:488.55CD38 inhibitor 3
CAS:<p>CD38 Inhibitor 3 (compound 1), with an IC50 of 11 nM, is a potent agent that enhances mitochondrial biogenesis, diminishes lactate levels, and augments both NAD</p>Fórmula:C16H14F3N7O3Pureza:98%Cor e Forma:SolidPeso molecular:409.32NLRP3-IN-20
CAS:<p>NLRP3-IN-20 (compound 11) is an orally administered inhibitor targeting the NLRP3 inflammasome, exhibiting potent inhibition with an IC50 of 25 nM against IL-1β</p>Fórmula:C22H27N3O3SPureza:98%Cor e Forma:SolidPeso molecular:413.53iNOS inhibitor-10
CAS:<p>iNOS Inhibitor-10, with an IC50 of 65 nM, exhibits antiproliferative effects on triple-negative breast cancer cells [1].</p>Fórmula:C22H23N3O2SPureza:98%Cor e Forma:SolidPeso molecular:393.5CK-119
CAS:<p>CK-119 inhibits IL-1, blocking corneal/conjunctival cell growth by halting DNA/RNA synthesis.</p>Fórmula:C21H23ClN4O5Cor e Forma:SolidPeso molecular:446.88COX-2-IN-32
CAS:<p>COX-2-IN-32 (Compound 2f) is a dual inhibitor of iNOS and COX-2, known to downregulate NF-κB expression.</p>Fórmula:C25H24O6Pureza:98%Cor e Forma:SolidPeso molecular:420.45SZM679
<p>SZM679: Oral RIPK1 inhibitor, Kd 8.6 nM, weak RIPK3 affinity (>5000 nM). Reduces inflammation, Tau phosphorylation in AD research.</p>Fórmula:C27H18F5N3O5SPureza:98%Cor e Forma:SolidPeso molecular:591.51HSR1304
CAS:<p>HSR1304 (5d) inhibits NFκB, key in diseases like cancer, offering research potential.</p>Fórmula:C24H21ClN2O3Cor e Forma:SolidPeso molecular:420.89Anti-inflammatory agent 21
CAS:<p>Compound 9o: orally active, low-toxicity anti-inflammatory; inhibits NO (IC50: 0.76 μM), blocks NF-κB/MAPK, reduces arthritis symptoms.</p>Fórmula:C24H21FO6Cor e Forma:SolidPeso molecular:424.42Fc 11a-2
CAS:<p>Fc 11a-2, an oral benzimidazole, potently inhibits NLRP3 inflammasome and caspase-1 to prevent colitis.</p>Fórmula:C16H16N2Cor e Forma:SolidPeso molecular:236.31IMD-catechol
CAS:<p>IMD-catechol: an imidazoquinolinone-based dimer with NF-κB activity; improves CT26 cancer treatment, low toxicity.</p>Fórmula:C31H34N6O3Pureza:98%Cor e Forma:SolidPeso molecular:538.64NLRP3-IN-19
CAS:<p>JT001 (NLRP3-IN-19) is a potent, specific, and orally active NLRP3 inhibitor that impedes the assembly of the NLRP3 inflammasome.</p>Fórmula:C19H22N4O4SPureza:98%Cor e Forma:SolidPeso molecular:402.47NF-κB-IN-8
CAS:<p>NF-κB-IN-8 is a competitive antagonist of LPS for MD-2 binding, and it impedes the expression of inflammatory factors by engaging MD-2.</p>Fórmula:C24H21N3O3Pureza:98%Cor e Forma:SolidPeso molecular:399.44COX-2-IN-22
CAS:<p>COX-2-IN-22 inhibits COX-2 (IC50: 8.6μM) and crosses the blood-brain barrier, also affects AChE, BChE, β-Secretase, LOX-5, DPPH.</p>Fórmula:C29H24O7Cor e Forma:SolidPeso molecular:484.5MIF-IN-3
CAS:<p>MIF-IN-3 inhibits MIF; useful in immunoinflammation research. (WO2021258272A1, compound 31)</p>Fórmula:C20H20N4O5SCor e Forma:SolidPeso molecular:428.46BBS-4
CAS:<p>BBS-4 inhibits NOS2 dimerization (IC50: 0.49 nM), guarding mice against sepsis-related heart issues.</p>Fórmula:C22H24N6O3Cor e Forma:SolidPeso molecular:420.46IMD-biphenylA
CAS:<p>IMD-biphenylA, a novel imidazoquinolinone-based dimer, functions as an NF-κB immunomodulator and enhances the adjuvant properties of small molecule immune</p>Fórmula:C35H33N5O2Pureza:98%Cor e Forma:SolidPeso molecular:555.67NF-κB-IN-11
CAS:<p>NF-κB-IN-11 (Compound 3i) is an inhibitor of NF-κB, effectively blocking TNF-α-induced NF-κB pathway activation and the nuclear translocation of NF-κB.</p>Fórmula:C19H18O5Pureza:98%Cor e Forma:SolidPeso molecular:326.34Nrf2 activator-4
CAS:Nrf2 activator-4 is an Nrf2 activator for the treatment of fatty liver disease associated with metabolic dysfunction in humans.Fórmula:C23H24ClF3N2O3Pureza:98.53%Cor e Forma:SolidPeso molecular:468.9Ro 106-9920
CAS:Inhibitor of NF-κB activationFórmula:C10H7N5OSPureza:98%Cor e Forma:SolidPeso molecular:245.26Loxoprofenol-SRS tromethamine
CAS:<p>Loxoprofenol-SRS tromethamine (HR1405-01), a metabolite of Loxoprofen, is a safe IV NSAID with strong anti-inflammatory and pain relief properties.</p>Fórmula:C19H31NO6Cor e Forma:SolidPeso molecular:369.45TNF-α-IN-18
CAS:<p>TNF-α-IN-18 is a small molecule TNF-α inhibitor that blocks NF-κB translocation, alleviates sepsis in models, and protects against rheumatoid arthritis in mice.</p>Fórmula:C16H7ClF2O4Pureza:99.77%Cor e Forma:SolidPeso molecular:336.67Simvastatin acid calcium hydrate
CAS:<p>Simvastatin (Tenivastatin) calcium hydrate is an oral HMG-CoA reductase inhibitor that reduces ROS by blocking indoxyl sulfate.</p>Fórmula:C25H40O6Cor e Forma:SolidPeso molecular:436.28249Antimicrobial agent-2
CAS:<p>Compound V-a: broad-spectrum, low-toxicity antimicrobial with no resistance, high bioavailability, damages membranes, targets MRSA (MIC 1μg/mL).</p>Fórmula:C16H14N2O4SCor e Forma:SolidPeso molecular:330.36Nrf2 activator-5
CAS:<p>Nrf2 activator-5 combats oxidative stress and inflammation in microglia, with potent antioxidant effects.</p>Fórmula:C25H30Cl2O6Cor e Forma:SolidPeso molecular:497.41NLRP3-IN-25
CAS:<p>NLRP3-IN-25 (compound 32), an orally available NLRP3 inhibitor, exhibits anti-inflammatory properties by attenuating renal injury in a mouse model of doxorubicin-induced glomerulonephritis and inhibiting IL-1β secretion in THP-1 cells, with an IC 50 value of 21 nM [1].</p>Fórmula:C17H19F3N4O5SCor e Forma:SolidPeso molecular:448.42CL264
CAS:<p>CL264, a selective agonist of TLR7, can be used in studies about innate immune signals.</p>Fórmula:C19H23N7O4Pureza:98.01%Cor e Forma:SolidPeso molecular:413.43Galectin-3-IN-1
CAS:<p>Galectin-3-IN-1 is a potent Gal-3 inhibitor, key in cancer-related metabolic processes.</p>Fórmula:C18H26O10SCor e Forma:SolidPeso molecular:434.46AR-C 102222
CAS:<p>AR-C 102222 is an iNOS inhibitor.</p>Fórmula:C19H16F2N6OPureza:98%Cor e Forma:SolidPeso molecular:382.37Indolokine A5
CAS:<p>Indolokine A5, a catabolite of L-cysteine, is a potent AhR agonist .</p>Fórmula:C13H8N2O3SCor e Forma:SolidPeso molecular:272.28NBC 19
CAS:<p>Potent NLRP3 inflammasome inhibitor (IC50 = 60-80 nM). Inhibits nigericin- and ATP-induced IL-1β release.</p>Fórmula:C24H26BCl3N2O2Cor e Forma:SolidPeso molecular:491.65COX-2/5-LOX-IN-3
CAS:<p>COX-2/5-LOX-IN-3 inhibits COX-2/5-LOX with IC50s: COX-1 45.73μM, COX-2 5.45μM, 5-LOX 4.33μM; promising for inflammation research.</p>Fórmula:C17H16ClN3O2SCor e Forma:SolidPeso molecular:361.85MIF degrader MD13
CAS:<p>MD13, a MIF-degrading PROTAC, disrupts vital protein interactions in cancer and inflammation, showing promise as a therapeutic research tool.</p>Fórmula:C35H35N5O8Cor e Forma:SolidPeso molecular:653.686,2',4'-Trimethoxyflavone
CAS:<p>The compound is an Aryl hydrocarbon receptor antagonist (EC50 = 0.9 μM). It also has no short term agonist activity and no species or promoter dependence.</p>Fórmula:C18H16O5Pureza:98%Cor e Forma:SolidPeso molecular:312.32Tilarginine citrate
CAS:<p>Tilarginine citrate is a competitive nitric oxide synthetase inhibitor.</p>Fórmula:C13H24N4O9Pureza:98%Cor e Forma:SolidPeso molecular:380.354Pifoxime
CAS:<p>Pifoxime: a NSAID with COX-1/2 inhibition, used in anti-inflammatory treatment and neuropsychiatric studies.</p>Fórmula:C15H20N2O3Cor e Forma:SolidPeso molecular:276.33IL-17A modulator-3
CAS:<p>IL-17A modulator-3 inhibits IL-17A/A, IC50 <10 μM, for inflammation, cancer, autoimmune research.</p>Fórmula:C34H50FN7O4Cor e Forma:SolidPeso molecular:639.8AChE/Nrf2 modulator 1
CAS:<p>AChE/Nrf2 modulator 1: oral, targets AChE/Nrf2, IC50s: 0.07 μM (eeAChE), 0.38 μM (hAChE); for Alzheimer's research.</p>Fórmula:C27H27FN4O2Cor e Forma:SolidPeso molecular:458.53
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