Imunologia e Inflamação
Os inibidores de imunologia e inflamação são compostos que modulam a resposta imunológica e os processos inflamatórios. Esses inibidores são cruciais para estudar os mecanismos de regulação imunológica, autoimunidade e inflamação crônica, bem como para desenvolver tratamentos para doenças inflamatórias, alergias e distúrbios relacionados ao sistema imunológico. Ao direcionar vias-chave no sistema imunológico, esses inibidores podem ajudar a reduzir respostas imunológicas excessivas ou inadequadas. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de alta qualidade para apoiar sua pesquisa em imunologia, inflamação e desenvolvimento terapêutico.
Subcategorias de "Imunologia e Inflamação"
- CCR(140 produtos)
- CXCR(153 produtos)
- Parede celular(5 produtos)
- Receptor IL(108 produtos)
- IκB/IKK(59 produtos)
- LTR(3 produtos)
- MALT(24 produtos)
- MRP(6 produtos)
- NADPH-oxidase(1 produtos)
- NF-κB(445 produtos)
- NOD(17 produtos)
- NOS(62 produtos)
- Nrf2(82 produtos)
- PGE Sintase(31 produtos)
- ROS(70 produtos)
- TGF-beta/Smad(59 produtos)
- TLR(74 produtos)
- Tiorredoxina(12 produtos)
- gp120/CD4(4 produtos)
Exibir 11 mais subcategorias
Foram encontrados 3269 produtos de "Imunologia e Inflamação"
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7-O-Methylaloeasinol
CAS:7-O-Methylaloeasinol is a useful organic compound for research related to life sciences. The catalog number is T126468 and the CAS number is 105317-69-9.Fórmula:C20H26O9Cor e Forma:SolidPeso molecular:410.419D-NAME (hydrochloride)
CAS:D-NAME, a less active NO synthase inhibitor enantiomer, has mild cardiovascular effects in rats; inactive in mouse nociception.Fórmula:C7H16ClN5O4Cor e Forma:SolidPeso molecular:269.69Hispaglabridin A
CAS:Hispaglabridin A, an effective antioxidant, inhibits lipid peroxidation [1].Fórmula:C25H28O4Cor e Forma:SolidPeso molecular:392.49AChE-IN-85
<p>AChE-IN-85 (Compound 7k) is an acetylcholinesterase inhibitor with an IC50 of 0.083 μM. It reduces nitric oxide (NO) release, the production of TNF-α and IL-1β, as well as levels of LDH and ROS, and inhibits Aβ42 aggregation. AChE-IN-85 exhibits anti-inflammatory and neuroprotective effects and is applicable for research on diseases such as Alzheimer's.</p>Cor e Forma:Odour SolidIPH5301
<p>IPH5301 is a human IgG1 monoclonal antibody (mAb) that targets NT5E/CD73. It features a functionally silenced Fc domain and specifically inhibits the enzymatic activity of both soluble and membrane-bound CD73, thereby restoring the proliferation of immune T cells. IPH5301 is applicable for research in anti-tumor immunotherapy. Recommended isotype control: HumanIgG1kappa, Isotype Control.</p>Cor e Forma:Odour LiquidSepteremophilane E
Septeremophilane E, from Septoria rudbeckiae fungus, inhibits NO production.Fórmula:C21H26O5Cor e Forma:SolidPeso molecular:358.43COX-2-IN-52
<p>COX-2-IN-52 (Compound 5l) is an orally active and selective COX-2 inhibitor with an IC50 of 54 nM. It can suppress the release of NO in cells, exhibiting anti-inflammatory properties. COX-2-IN-52 offers high gastrointestinal safety and is suitable for research on oral anti-inflammatory drugs.</p>Fórmula:C16H13IN4O4S2Cor e Forma:SolidPeso molecular:516.333Cyclo(L-Pro-L-Val)
CAS:<p>Cyclo(L-Pro-L-Val), from Mycobacterium spp., has anti-inflammatory effects, hinders phytopathogens, and suppresses IKKα, NF-κB, iNOS, and COX-2 activation.</p>Fórmula:C10H16N2O2Pureza:98.18%Cor e Forma:SolidPeso molecular:196.25C12-rrw-NH2
C12-rrw-NH2 (Compound Lip7) is an antimicrobial agent effective against Gram-positive bacteria, particularly demonstrating significant activity against Methicillin-resistant Staphylococcus aureus (MRSA). It induces bacterial cell death by depolarizing the bacterial cell membrane, disrupting membrane integrity, causing nucleic acid and protein leakage, and promoting the generation of Reactive Oxygen Species (ROS). C12-rrw-NH2 is applicable in research focused on developing highly stable antimicrobial peptides.Fórmula:C35H58N10O5Cor e Forma:SolidPeso molecular:698.9Nrf2/HO-1 activator 3
<p>Nrf2/HO-1 Activator 3 (Compound C3a) is an activator of the Nrf2 signaling pathway that facilitates the translocation of Nrf2 into the nucleus and enhances the expression of heme oxygenase-1 (HO-1). In H9c2 cardiomyocytes subjected to H2O2 or high glucose stimulation, Nrf2/HO-1 Activator 3 inhibits the excessive expression of ROS and MDA, suppressing cell viability and colony formation, thereby exhibiting antioxidant activity.</p>Fórmula:C27H26N2O6Cor e Forma:SolidPeso molecular:474.51TLR4 agonist-1 TEA
<p>TLR4 agonist-1 (TEA, compound 17a) is a potent activator of Toll-like Receptor 4 (TLR4) and prompts the production of MIP-1β in RAW 264.7 and MM6 cells [1].</p>Cor e Forma:Odour SolidAChE-IN-3
CAS:AChE-IN-3 had inhibitory effect on AChE and stronger inhibitory effect on NO, with EC50 of 0.57 μM.Fórmula:C25H21N3O4Pureza:99.88%Cor e Forma:SolidPeso molecular:427.45Antiviral agent 38
CAS:(6R)-6-Tert-butyl-10-(3-methoxypropoxy)-dihydro-2-oxo-indazole carboxylic acid has antiviral and antibacterial properties, useful for Hepatitis B research.Fórmula:C23H27N3O5Pureza:99.99%Cor e Forma:SoildPeso molecular:425.48ZL-1102
<p>ZL-1102 is a humanized monoclonal antibody inhibitor targeting interleukin-17A (IL-17A). SCH-900117 is being investigated for its potential use in the treatment of autoimmune diseases such as psoriasis and rheumatoid arthritis.</p>Cor e Forma:Odour LiquidPascolizumab
CAS:<p>Pascolizumab (SB-240683) is a humanized monoclonal antibody against IL-4. Pascolizumab has asthmatic effects and can be used to study allergic rhinitis.</p>Pureza:> 95%Cor e Forma:LiquidPeso molecular:147.18 kDaAChE-IN-82
<p>AChE-IN-82 (compound 49) is an acetylcholinesterase (AChE) inhibitor. It inhibits eeAChE, eqBChE, hMAO-A, hMAO-B, and BACE-1 with IC50 values of 0.072, 9.81, 14.52, 0.024, and 2.42 μM, respectively. Additionally, AChE-IN-82 inhibits COX-1, COX-2, and 5-LOX with IC50 values of 60.41, 0.187, and 0.18 μM, respectively. The compound also demonstrates strong neuroprotective effects by significantly reducing H2O2-induced oxidative stress.</p>Fórmula:C21H18N4O5S2Cor e Forma:SolidPeso molecular:470.52NVP-DKY709
CAS:NVP-DKY709 is a potent IKZF2 inhibitor for the treatment of cancers.Fórmula:C25H27N3O3Pureza:99%Cor e Forma:SolidPeso molecular:417.5ROS inducer 8
<p>ROS inducer 8 (Compound 11g) acts as an inhibitor of glutathione (GSH) and promotes the accumulation of reactive oxygen species (ROS) in Enterococcus faecalis, exhibiting antibacterial properties. It is capable of disrupting biofilms and inhibiting S. aureus and E. faecalis with minimum inhibitory concentrations (MICs) of 8 μg/mL and 2 μg/mL, respectively, demonstrating a post-antibiotic effect. Additionally, ROS inducer 8 shows low hemolytic toxicity on sheep red blood cells with an HC50 greater than 1280 μg/mL.</p>Fórmula:C26H31FN6O6Cor e Forma:SolidPeso molecular:542.56Keap1-Nrf2-IN-25
Keap1-Nrf2-IN-25 (Compound 19) is a potent Keap1-Nrf2 inhibitor with an IC50 of 0.55 μM and exhibits a Keap1 binding affinity (Kd of 0.50 μM). This compound activates Nrf2, reducing reactive oxygen species (ROS) and pro-inflammatory cytokines (IL-1β, IL-6). Additionally, Keap1-Nrf2-IN-25 provides protective effects against DSS-induced colitis.Fórmula:C25H28N2O6SCor e Forma:SolidPeso molecular:484.565STING agonist-3 trihydrochloride
STING agonist-3 is a selective, non-nucleotide small-molecule with anti-tumor properties and potential in cancer therapy.Fórmula:C37H45Cl3N12O6Pureza:98%Cor e Forma:SolidPeso molecular:860.19
