Imunologia e Inflamação
Os inibidores de imunologia e inflamação são compostos que modulam a resposta imunológica e os processos inflamatórios. Esses inibidores são cruciais para estudar os mecanismos de regulação imunológica, autoimunidade e inflamação crônica, bem como para desenvolver tratamentos para doenças inflamatórias, alergias e distúrbios relacionados ao sistema imunológico. Ao direcionar vias-chave no sistema imunológico, esses inibidores podem ajudar a reduzir respostas imunológicas excessivas ou inadequadas. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de alta qualidade para apoiar sua pesquisa em imunologia, inflamação e desenvolvimento terapêutico.
Subcategorias de "Imunologia e Inflamação"
- CCR(136 produtos)
- CXCR(149 produtos)
- Parede celular(5 produtos)
- Receptor IL(112 produtos)
- IκB/IKK(59 produtos)
- LTR(3 produtos)
- MALT(23 produtos)
- MRP(6 produtos)
- NADPH-oxidase(1 produtos)
- NF-κB(443 produtos)
- NOD(18 produtos)
- NOS(63 produtos)
- Nrf2(78 produtos)
- PGE Sintase(31 produtos)
- ROS(69 produtos)
- TGF-beta/Smad(58 produtos)
- TLR(66 produtos)
- Tiorredoxina(12 produtos)
- gp120/CD4(4 produtos)
Exibir 11 mais subcategorias
Foram encontrados 3054 produtos de "Imunologia e Inflamação"
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Tri(TLR4-IN-C34-C2-amide-PEG1)-amide-C3-COOH
<p>Tri(TLR4-IN-C34-C2-amide-PEG1)-amide-C3-COOH, a linker with TLR4-IN-C34, reduces inflammation in mice.</p>Fórmula:C78H125N7O36Cor e Forma:SolidPeso molecular:1736.85AMG-424
<p>AMG-424 (XmAb968) is a human bispecific antibody (bsAb) targeting CD38 and CD3E. It effectively kills cancer cells that express CD38, stimulates T cell proliferation, and reduces cytokine release. AMG-424 exhibits antitumor activity in mouse cancer models with bone marrow invasion and induces peripheral B cell depletion in cynomolgus monkeys. It is used in studies of multiple myeloma. Recommended isotype control: half-IG G1-kappa/(scFv-heavy-lambda)-h-CH2-CH3.</p>Cor e Forma:Odour LiquidHistone Modification Compound Library
<p>A unique collection of xnum histone modification related compounds for high throughput screening (HTS) and high content screening (HCS);</p>Cor e Forma:Odour SolidDOPAL
CAS:<p>DOPAL, a neurotoxic aldehyde from dopamine metabolism, is linked to Parkinson's and can convert to DOPAC or DOPET.</p>Fórmula:C8H8O3Cor e Forma:SolidPeso molecular:152.15Dihydromyristicin
CAS:<p>Dihydromyristicin, a plant flavonoid, curbs inflammation by inhibiting ROS and PI3K/Akt/NF-κB pathways.</p>Fórmula:C11H14O3Cor e Forma:SolidPeso molecular:194.23Ketoprofen lysine salt
CAS:<p>Ketoprofen lysine salt is a lysine salt of ketoprofen, a Non-Steroidal Anti-Inflammatory Drug</p>Fórmula:C22H28N2O5Cor e Forma:SolidPeso molecular:400.48MTvkPABC-P5
<p>MTvkPABC-P5d, functioning as a TLR7 agonist, serves as an immune stimulant and is utilized in the synthesis of immune-stimulating antibody conjugates (ISACs) [1</p>Fórmula:C52H73N11O14Cor e Forma:SolidPeso molecular:1076.2Chemokine Inhibitor Library
<p>A unique collection of xnum chemokines or chemokine receptors targeted compounds for high throughput and high content screening;</p>Cor e Forma:Odour SolidN-Acetyldopamine dimer-2
CAS:<p>Compound 2, an N-acetyldopamine dimer from Periostracum Cicadae, exhibits antioxidant and anti-inflammatory properties.</p>Fórmula:C20H20N2O6Cor e Forma:SolidPeso molecular:384.38PS 1145 dihydrochloride
CAS:<p>IκB kinase (IKK) inhibitor</p>Fórmula:C17H13Cl3N4OPureza:98%Cor e Forma:SolidPeso molecular:395.67BuChE-IN-20
<p>BuChE-IN-20 is a selective hBuChE inhibitor (IC50= 0.13 μM) with the ability to cross the blood-brain barrier (BBB). This compound, a derivative of L-Tryptophan, exhibits neuroprotective effects by inhibiting nitric oxide (NO) production and reducing reactive oxygen species (ROS) levels. It effectively suppresses the self-aggregation of amyloid-beta (Aβ) peptides and is applicable in Alzheimer's disease research.</p>Cor e Forma:Odour SolidItolizumab
CAS:<p>Itolizumab (Anti-Human CD6 Recombinant Antibody) is a recombinant anti-CD6 monoclonal antibody that humanizes the extracellular SRCR distal domain 1 of CD6.</p>Pureza:> 95%Cor e Forma:LiquidPeso molecular:144.82 kDaTranscription Factor-Targeted Compound Library
<p>Well-chosen xnum compounds with unique structures targeting transcription factor;</p>Cor e Forma:Odour SolidPterisolic acid B
<p>Pterisolic acid B is a useful organic compound for research related to life sciences and the catalog number is T125924.</p>Fórmula:C20H26O4Cor e Forma:SolidPeso molecular:330.424Nonsteroidal Anti-Inflammatory Compound Library
<p>xnum non-steroidal anti-inflammatory compounds for high-throughput and high-content screening.</p>Cor e Forma:Odour SolidIL-17-IN-3
<p>IL-17-IN-3 (compound 11) is an IL-17A inhibitor with an IC50 value of 35 nM. In a rat tolerance study, it showed no adverse reactions when administered at doses up to 300 mg/kg/day for four consecutive days.</p>Fórmula:C22H25F6N5O3SCor e Forma:SolidPeso molecular:553.521Post-Translational Modification Compound Library
<p>Contains xnum active small molecules for research related to post-translational modifications (PTMs);</p>Cor e Forma:Odour SolidBiotin-labeled ODN 1018 sodium
<p>Biotin-labeled ODN 1018 (sodium), a TLR-9 agonist oligodeoxynucleotide, serves as a tool for assessing cellular uptake and localization of CpG ODNs through</p>Cor e Forma:Odour SolidFITC-labeled ODN 1826 sodium
<p>FITC-labeled ODN 1826 (sodium), a class B CpG ODN (oligodeoxynucleotide) and TLR9 agonist, facilitates the assessment of CpG ODN cellular uptake and</p>Cor e Forma:Odour SolidJAB-BX102
<p>JAB-BX102 is a human monoclonal antibody (mAb) that targets NT5E/CD73. It is applicable in research studies involving breast cancer, pancreatic cancer, prostate cancer, and other cancers.</p>Cor e Forma:Odour LiquidhCYP1B1-IN-1
<p>hCYP1B1-IN-1 (compound B18) is an inhibitor of hCYP1B1 with an IC50 value of 3.6 nM and also acts as an antagonist of the Aryl Hydrocarbon Receptor.</p>Fórmula:C18H14ClF3O3Cor e Forma:SolidPeso molecular:370.75Inhibitor Library
<p>A unique collection of 8328 inhibitors for research in cell signaling, high throughput screening (HTS) and high content screening (HCS) for new drugs;</p>Cor e Forma:Odour SolidP2X7-IN-2 TFA
P2X7-IN-2 TFA inhibits IL-Iβ release (IC50=0.01nM), used in autoimmunity, inflammation & cardiovascular research.Fórmula:C24H22F7N3O4Cor e Forma:SolidPeso molecular:549.44NLRP3 modulators 1
CAS:<p>Compound 107 (WO2017184746A1) is a potent NLRP3 modulator, useful for studying diseases linked to NLRP3 activity.</p>Fórmula:C17H18N6OCor e Forma:SolidPeso molecular:322.372PMX-53
CAS:<p>PMX-53: MrgX2 agonist; C5aR antagonist; lessens atherosclerotic lesions & metastasis in mice; blocks rat hypernociception.</p>Fórmula:C47H65N11O7Pureza:98%Cor e Forma:SolidPeso molecular:896.09L-156,602
CAS:<p>L-156,602 has a wide range of applications in life science related research.</p>Fórmula:C38H64N8O13Cor e Forma:SolidPeso molecular:840.973Ziltivekimab
CAS:<p>Ziltivekimab (MEDI 5117) is a CHO-expressed humanized monoclonal antibody targeting IL-6/IFNb2 for use in immune system diseases.</p>Pureza:95% - 97.9% (SDS-PAGE); 97.3% (SEC-HPLC)Cor e Forma:SoildSTING agonist-25
CAS:<p>STING agonist-25 is a non-nucleotide that activates STING, enhances immune response, and is active against SARS-CoV strains.</p>Fórmula:C36H41N13O6Cor e Forma:SolidPeso molecular:751.79STING-IN-14
CAS:<p>STING-IN-14 is a STING inhibitor with an IC50 of 0.6 nM. It effectively suppresses the activation of the IRF pathway in THP1-DualTM cells. This compound is applicable in research related to autoimmune diseases.</p>Fórmula:C46H43F2N11O5Cor e Forma:SolidPeso molecular:867.901Histamine & Melatonin Receptor-Targeted Compound Library
<p>A unique collection of xnum compounds targeting histaminergic receptor and melatonin receptor for high throughput screening (HTS) and high content screening (HCS</p>Cor e Forma:Odour SolidAc-macropa
Ac-macropa is a conjugate of Actinium-225 that targets PSMA, and it is useful for researching prostate cancer.Fórmula:C39H52AcN6O9SPeso molecular:1007.3794Xanthine oxidase-IN-12
<p>Xanthine oxidase-IN-12 (Compound 11), an inhibitor of xanthine oxidase (XO), possesses an IC50 value of 91 nM and exhibits antioxidant properties, additionally</p>Pureza:98%Cor e Forma:Odour SolidGuretolimod hydrochloride
<p>Guretolimod hydrochloride acts as an agonist for Toll-like receptor 7 (TLR7) [1].</p>Fórmula:C24H35ClF3N5O4Cor e Forma:SolidPeso molecular:550.018-Nitroguanine
CAS:<p>8-Nitroguanine is a product of DNA nitration damage caused by reactive nitrogen species and may be a potential biomarker for the progression of malignant</p>Fórmula:C5H4N6O3Cor e Forma:SolidPeso molecular:196.12MAPK Inhibitor Library
<p>A unique collection of 365 compounds targeting MAPK signaling for drug discovery in MAPK related diseases;</p>Cor e Forma:Odour SolidIL-1β-IN-1
CAS:<p>IL-1β-IN-1, a cannabidiol derivative, acts as a potent inhibitor of IL-1β, exhibiting significant anti-inflammatory and pain relief properties [1].</p>Fórmula:C22H34O2Cor e Forma:SolidPeso molecular:330.5Eramkafusp Alfa
<p>Eramkafusp alfa is a human IgG1 antibody that targets the murine B lymphocyte antigen CD20, also known as MS4A1 [1].</p>Cor e Forma:Odour LiquidProstaglandin D synthase
CAS:<p>Prostaglandin D synthase is a biomarker for meningioma cells and coronary artery disease. Lipocalin-type prostaglandin D synthase (L-PGDS) is found in human coronary atherosclerotic plaques and can be detected in human serum.</p>Cor e Forma:SolidMurrayafoline A
CAS:<p>Murrayafoline A is a useful organic compound for research related to life sciences. The catalog number is T124835 and the CAS number is 4532-33-6.</p>Fórmula:C14H13NOCor e Forma:SolidPeso molecular:211.264Isuventatug
CAS:<p>Isuventatug is a monoclonal antibody that targets human MICA (MHC I chain-related molecule A) and MICB (MHC I chain-related molecule B). By binding to MICA and MICB, Isuventatug modulates the interaction between immune cells and tumor cells, exhibiting anti-tumor activity. This compound holds potential for research in cancer immunotherapy.</p>Cor e Forma:LiquidPIC1 PA TFA
<p>PIC1 PATFA is the trifluoroacetate form of PIC1 PA. PIC1 PA TFA is a peptide composed of 15 amino acids and serves as an effective PIC1 analog capable of inhibiting complement activation mediated by the classical pathway.</p>Fórmula:C71H123N19O21S2·xC2HF3O2Cor e Forma:SolidPROTAC STING degrader-3
<p>PROTACSTING degrader-3 (Compound ST9) is a STINGPROTAC-type degrader with a DC50 of 0.62 μM. It induces STING degradation via the ubiquitin-proteasome pathway. This compound exerts anti-inflammatory effects by inhibiting the STING/TBK1/NF-κB signaling. Additionally, it offers renal protection and can be used in research on acute kidney injury.</p>Cor e Forma:Odour SolidBRCA2-IN-1
<p>BRCA2-IN-1 (Compound 3j) is a potential BRCA2 inhibitor with antiproliferative activity against the breast cancer MCF-7 cell line. This compound also demonstrates DPPH radical scavenging ability, with an IC50 value of 12.36 µM.</p>Cor e Forma:Odour SolidEftilagimod alfa
CAS:<p>Eftilagimod alfa (IMP321), a recombinant LAG-3Ig fusion protein, binds to MHC class II and mediates the activation of antigen-presenting cells (APCs), which in</p>Cor e Forma:LiquidSDH-IN-23
<p>SDH-IN-23 (Compound B21) is an SDH inhibitor with exceptional nematicidal activity. It can suppress nematode feeding, reproduction, and embryonic development while also inducing lethal effects through mechanisms such as oxidative stress, intestinal damage, and SDH inhibition.</p>Fórmula:C19H11ClF6N2O2Cor e Forma:SolidPeso molecular:448.75Exosome Compound Library
<p>76 exosome-related compounds that can be used for high-throughput and high-content screening.</p>Cor e Forma:Odour SolidLemnalol
CAS:<p>Lemnalol, from Lemnalia cervicorni, has anti-inflammatory and analgesic properties.</p>Fórmula:C15H24OPureza:98%Cor e Forma:SolidPeso molecular:220.35PROTAC IRAK4 degrader-3
CAS:PROTAC IRAK4 degrader-3 is a PROTAC-induced IRAK4 degrader based on von Hippel-Lindau.Fórmula:C57H68FN11O8SCor e Forma:SolidPeso molecular:1086.3Diprovocim-X
<p>Diprovocim-X, a potent TLR1/2 agonist, has EC50s of 0.14nM (hTLR) and 0.75nM (mTLR), enhances mice's adaptive immunity.</p>Fórmula:C66H83N7O10Cor e Forma:SolidPeso molecular:1134.41Endoplasmic Reticulum Stress Compound Library
<p>A unique collection of 193 endoplasmic reticulum stress (ER stress) related compounds used for high throughput screening (HTS) and high content screening (HCS);</p>Cor e Forma:Odour Solid
