Imunologia e Inflamação
Os inibidores de imunologia e inflamação são compostos que modulam a resposta imunológica e os processos inflamatórios. Esses inibidores são cruciais para estudar os mecanismos de regulação imunológica, autoimunidade e inflamação crônica, bem como para desenvolver tratamentos para doenças inflamatórias, alergias e distúrbios relacionados ao sistema imunológico. Ao direcionar vias-chave no sistema imunológico, esses inibidores podem ajudar a reduzir respostas imunológicas excessivas ou inadequadas. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de alta qualidade para apoiar sua pesquisa em imunologia, inflamação e desenvolvimento terapêutico.
Subcategorias de "Imunologia e Inflamação"
- CCR(136 produtos)
- CXCR(149 produtos)
- Parede celular(5 produtos)
- Receptor IL(112 produtos)
- IκB/IKK(59 produtos)
- LTR(3 produtos)
- MALT(23 produtos)
- MRP(6 produtos)
- NADPH-oxidase(1 produtos)
- NF-κB(443 produtos)
- NOD(18 produtos)
- NOS(63 produtos)
- Nrf2(78 produtos)
- PGE Sintase(31 produtos)
- ROS(69 produtos)
- TGF-beta/Smad(58 produtos)
- TLR(66 produtos)
- Tiorredoxina(12 produtos)
- gp120/CD4(4 produtos)
Exibir 11 mais subcategorias
Foram encontrados 3054 produtos de "Imunologia e Inflamação"
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E6446
CAS:<p>E6446 inhibits Toll-like receptor (TLR)7 and 9 signaling.</p>Fórmula:C27H35N3O3Pureza:98.72%Cor e Forma:SolidPeso molecular:449.59IQ-1S free acid
CAS:<p>IQ-1S free acid (IQ-1S) is an effective and specific c-Jun N-Terminal Kinase Inhibitor. IQ-1S inhibits murine delayed-type hypersensitivity.</p>Fórmula:C15H9N3OPureza:97.92% - 99.05%Cor e Forma:SolidPeso molecular:247.25Tyrosol
CAS:<p>Tyrosol (2-(4-Hydroxyphenyl)ethanol) is a phenolic antioxidant that is naturally present in several foods such as wines and green tea and is present most</p>Fórmula:C8H10O2Pureza:99.24% - 99.86%Cor e Forma:SolidPeso molecular:138.16Malachite green oxalate
CAS:<p>Malachite green oxalate is a triphenylmethane dye which can be used to detect the release of phosphate in enzymatic reactions.</p>Fórmula:C23H25N2·C2HO4C2H2O4Cor e Forma:Dark Green Crystals With A Metallic LusterPeso molecular:463.51PF-3845
CAS:<p>PF-3845 is a potent, selective and irreversible FAAH inhibitor with Ki of 230 nM, showing negligible activity against FAAH2.</p>Fórmula:C24H23F3N4O2Pureza:99.54% - 99.58%Cor e Forma:SolidPeso molecular:456.46CADD522
CAS:<p>CADD522 (MFCD00167693) is a potent inhibitor of runt-related transcription factor-2 (RUNX2)-DNA binding with an IC50 of 10 nM, with antitumor activity</p>Fórmula:C15H13Cl2NO3Pureza:97.74%Cor e Forma:SolidPeso molecular:326.17Tapinarof
CAS:<p>Tapinarof (Benvitimod) is targeted as a topical cream treatment for psoriasis, a chronic autoimmune skin disease.</p>Fórmula:C17H18O2Pureza:99.64% - >99.99%Cor e Forma:SolidPeso molecular:254.32RO2959 Hydrochloride
CAS:<p>RO2959 Hydrochloride (RO2959 HCl) is a potent and selective inhibitor of CRAC channel(IC50: 402 nM). It is also a potent inhibitor of human IL-2.</p>Fórmula:C21H20ClF2N5OSPureza:99.24%Cor e Forma:SolidPeso molecular:463.93TBK1/IKKε-IN-5
CAS:<p>TBK1/IKKε-IN-5 is a dual TBK1 and IKKε inhibitor(IC50 of 1 nM and 5.6 nM, respectively).</p>Fórmula:C28H31N7O3Pureza:98.77%Cor e Forma:SolidPeso molecular:513.5920(S)-Ginsenoside Rg3
CAS:<p>20(S)-Ginsenoside Rg3 (Rg3) possess an ability to inhibit the lung metastasis of tumor cells via inhibition of the adhesion and invasion of tumor cells.</p>Fórmula:C42H72O13Pureza:98.11% - 99.93%Cor e Forma:SolidPeso molecular:785.01Apilimod mesylate
CAS:<p>Apilimod mesylate (STA 5326 mesylate) is a potent IL-12/IL-23 inhibitor.</p>Fórmula:C25H34N6O8S2Pureza:99.51% - ≥95%Cor e Forma:SolidPeso molecular:610.7Ustekinumab
CAS:<p>Ustekinumab is an anti-IL-12/IL-23 IgG1κ human monoclonal antibody.</p>Pureza:98% - 99.70%Cor e Forma:LiquidPeso molecular:148 kDa2,4-Diamino-6-hydroxypyrimidine
CAS:<p>2,4-Diamino-6-hydroxypyrimidine (DAHP) (DAHP) is a selective, specific inhibitor of GTP cyclohydrolase I, the rate limiting step for de novo pterin synthesis</p>Fórmula:C4H6N4OPureza:99.82%Cor e Forma:White Solid CrystalsPeso molecular:126.1211-Keto-β-boswellic acid
CAS:<p>11-Keto-beta-boswellic acid, a novel Nrf2 activator, and a selective 5-lipoxygenase (5-LOX) inhibitor, exerts dose dependent cardioprotective effect manifested.</p>Fórmula:C30H46O4Pureza:99.68%Cor e Forma:SolidPeso molecular:470.68α-Demethylnaproxen
CAS:<p>α-Demethylnaproxen is a competitive inhibitor of COX(Ki values of 21 and 19 μM for ovine COX-1 and -2, respectively)</p>Fórmula:C13H12O3Pureza:97.57%Cor e Forma:Off-White SolidPeso molecular:216.23Articaine
CAS:<p>Articaine (Hoe-045 free base), an amide anesthetic featuring an ester group, effectively relieves pain by reversibly binding to the α-subunit of the voltage-</p>Fórmula:C13H20N2O3SCor e Forma:SolidPeso molecular:284.37Bay 11-7085
CAS:<p>Bay 11-7085 can irreversibly inhibit the IκBα phosphorylation induced by TNFα (IC50: 10 μM).</p>Fórmula:C13H15NO2SPureza:99.76% - 99.94%Cor e Forma:White SolidPeso molecular:249.33Tomatidine
CAS:<p>Tomatidine serves as an anti-inflammatory agent by inhibiting NF-κB and JNK signaling pathways.</p>Fórmula:C27H45NO2Pureza:99.94% - 99.98%Cor e Forma:SolidPeso molecular:415.65Glu-urea-Lys TFA(1025796-69-3 free base)
<p>Glu-urea-Lys TFA (1025796-69-3 free base) is a PSMA inhibitor.</p>Fórmula:C14H22F3N3O9Pureza:99.91%Cor e Forma:SolidPeso molecular:433.34Tolmetin
CAS:<p>Tolmetin (Tolectin) NSAID; acts as a cyclooxygenase inhibitor; classified as an anti-inflammatory.</p>Fórmula:C15H15NO3Pureza:99.74% - >99.99%Cor e Forma:Off-White Crystalline PowerPeso molecular:257.28Evolocumab
CAS:<p>Evolocumab is an inhibitor of the humanized monoclonal antibody PCSK9.Evolocumab can inhibit the binding of PCSK9 to LDLR.Cost-effective and quality-assured.</p>Pureza:95% - 98.3%Cor e Forma:LiquidPeso molecular:144 kDaFas C-Terminal Tripeptide Acetate
<p>Fas C-Terminal Tripeptide Acetate shows inhibitory activity of Fas/FAP-1 binding.</p>Fórmula:C18H33N3O8Pureza:99.12%Cor e Forma:SolidPeso molecular:419.47Indacaterol
CAS:<p>Indacaterol (Onbrez; Arcapta) is a β2-Adrenergic Agonist. The mechanism of action of indacaterol is as an Adrenergic beta2-Agonist.</p>Fórmula:C24H28N2O3Pureza:99.96%Cor e Forma:SolidPeso molecular:392.49CU-CPT-9a
CAS:<p>CU-CPT-9a is a potent TLR8 inhibitor (IC50 : 0.5 nM), that suppresses TLR8-mediated proinflammatory signaling in various cell lines and human primary cells-</p>Fórmula:C17H15NO2Pureza:99.01%Cor e Forma:SolidPeso molecular:265.31NOD-IN-1
CAS:<p>NOD-IN-1 (Compound 4) is a potent mixed inhibitor of nucleotide-binding oligomerization domain (NOD)-like receptors.</p>Fórmula:C18H17NO4SPureza:99.93% - >99.99%Cor e Forma:SolidPeso molecular:343.45-fluoro 203
CAS:5-fluoro 203 (NSC-703786) is a cytotoxic molecule leading to cell death by forming DNA adducts.Fórmula:C14H11FN2SPureza:97.61%Cor e Forma:SolidPeso molecular:258.31ITE
CAS:<p>ITE is a potent endogenous agonist of aryl hydrocarbon receptor (AhR) (Ki : 3 nM), has immunosuppressive activity.</p>Fórmula:C14H10N2O3SPureza:97.91% - 99.14%Cor e Forma:SolidPeso molecular:286.31BX795
CAS:<p>BX795 selectively inhibits PDK1 (IC50: 6 nM), 140x over PKA, 1600x over PKC, 100x over GSK3β in cell-free assays.</p>Fórmula:C23H26IN7O2SPureza:98% - 99.57%Cor e Forma:SolidPeso molecular:591.47DMNQ
CAS:DMNQ: a 1,4-naphthoquinone that boosts intracellular superoxide & H2O2 by redox-cycling, raising ROS levels.Fórmula:C12H10O4Pureza:99.12% - 99.42%Cor e Forma:SolidPeso molecular:218.21IKKγ NBD Inhibitory Peptide acetate
<p>IKKγ NBD Inhibitory Peptide acetate is a NEMO-binding domain peptide (NBD peptide) acetate corresponding to the NEMO amino-terminal alpha-helical region.</p>Pureza:99.15%Cor e Forma:SolidPeso molecular:N/ADendrophenol
CAS:<p>Dendrophenol (Moscatilin) is a natural product isolated from the stem of Dendrobium loddigesii Rolfe, act as a NF-κB inhibitor. Antineoplastic activity.</p>Fórmula:C17H20O5Pureza:98.2% - 99.36%Cor e Forma:SolidPeso molecular:304.34DMPO
CAS:<p>DMPO is a water-soluble spin trap for measuring free radicals via electron spin resonance.</p>Fórmula:C6H11NOPureza:99.39% - 99.46%Cor e Forma:White To Faintly Yellow SolidPeso molecular:113.16Polygalasaponin F
CAS:<p>Polygalasaponin F reduces neuroinflammation, blocks TNF-α/NO, and protects neurons by modulating NF-kB and NMDAR pathways.</p>Fórmula:C53H86O23Pureza:98% - 99.83%Cor e Forma:SolidPeso molecular:1091.24Coelenterazine
CAS:<p>Coelenterazine is a superoxide anion-sensitive chemiluminescent probe.Cost-effective and quality-assured.</p>Fórmula:C26H21N3O3Pureza:97.05% - 99.02%Cor e Forma:Yellow SolidPeso molecular:423.468-Deoxygartanin
CAS:<p>8-Deoxygartanin is a butyrylcholinesterase (BChE) selective inhibitor, it exhibits significant inhibition of self-induced α2-amyloid (Aα2) aggregation, it has</p>Fórmula:C23H24O5Pureza:99.04% - 99.88%Cor e Forma:SolidPeso molecular:380.43Vamorolone
CAS:<p>Vamorolone (VBP15) is a steroid-like drug that treats muscular dystrophy with fewer side effects and inhibits NF-κB.</p>Fórmula:C22H28O4Pureza:99.54%Cor e Forma:SolidPeso molecular:356.46N-acetylcysteine amide
CAS:<p>N-Acetylcysteine amide is a thiol antioxidant and a neuroprotective agent with cell permeability and blood-brain barrier permeability. Cost-effective and quality-assured.</p>Fórmula:C5H10N2O2SPureza:99.36% - ≥98%Cor e Forma:SolidPeso molecular:162.21Lumiracoxib
CAS:<p>Lumiracoxib (Prexige) is a novel, selective COX-2 inhibitor with IC50 and Ki of 0.14 μM and 0.06 μM, exhibits 515-fold selectivity over COX-1. Phase 4.</p>Fórmula:C15H13ClFNO2Pureza:96.64% - 99.77%Cor e Forma:Pale Yellow SolidPeso molecular:293.72GLX351322
CAS:<p>GLX351322 is NADPH Oxidase 4 Inhibitor with IC50 of 5 μM.</p>Fórmula:C21H25N3O5SPureza:99.93%Cor e Forma:SolidPeso molecular:431.51Robinin
CAS:<p>Robinin: a kaempferol-derived flavone glycoside with antibacterial, diuretic traits; minimal effect on Colo 320 MDR1/LRP resistance; detected in MCF-7 cells.</p>Fórmula:C33H40O19Pureza:98.78% - 99.13%Cor e Forma:SolidPeso molecular:740.66Carbidopa monohydrate
CAS:<p>Carbidopa monohydrate (S(-)-Carbidopa) is an inhibitor of DOPA decarboxylase, preventing the conversion of levodopa to dopamine.</p>Fórmula:C10H16N2O5Pureza:98.11% - 98.30%Cor e Forma:SolidPeso molecular:244.24Demethyleneberberine
CAS:<p>Demethyleneberberine, which is composed of a potential antioxidant structure, could penetrate the membrane of mitochondria and accumulate in mitochondria either</p>Fórmula:C19H18NO4Pureza:98.08% - 99.18%Cor e Forma:SolidPeso molecular:324.35JTE-607
CAS:<p>JTE-607 is a cytokine production inhibitor. JTE-607 induces apoptosis accompanied by an increase in p21waf1/cip1 in acute myelogenous leukemia cells.</p>Fórmula:C25H33Cl4N3O5Pureza:97.88%Cor e Forma:SolidPeso molecular:597.36Danicopan
CAS:<p>Danicopan (ACH-4471), an oral factor D inhibitor, binds strongly (Kd 0.54 nM) and may treat PNH and aHUS.</p>Fórmula:C26H23BrFN7O3Pureza:99.94%Cor e Forma:SolidPeso molecular:580.41Dauricine
CAS:<p>1.</p>Fórmula:C38H44N2O6Pureza:99.24% - 99.75%Cor e Forma:White PowderPeso molecular:624.77Ginsenoside Rb3
CAS:<p>Ginsenoside Rb3 (Gypenoside IV) is a natural triterpenoid saponin, exhibiting inhibition effect on TNFα-induced NF-κB transcriptional activity.</p>Fórmula:C53H90O22Pureza:98% - 99.98%Cor e Forma:SolidPeso molecular:1079.27Caffeic Acid Phenethyl Ester
CAS:<p>CAPE, in propolis, blocks NF-kappa B, suppresses p70S6K/Akt pathways, and inhibits PDGF, aiding in cancer protection and immune modulation.</p>Fórmula:C17H16O4Pureza:99.18% - 99.35%Cor e Forma:Less Transparent Liquid Colorless Transparent LiquidPeso molecular:284.31IRAK-1-4 Inhibitor I
CAS:<p>IRAK-1-4 Inhibitor I is a dual inhibitor of IRAK4 and IRAK1.</p>Fórmula:C20H21N5O4Pureza:98% - 99.89%Cor e Forma:SolidPeso molecular:395.41Ginsenoside Rg2
CAS:<p>Ginsenoside Rg2 (Chikusetsusaponin I) is one of the major active components of ginseng, act as an NF-κB inhibitor.</p>Fórmula:C42H72O13Pureza:99.77% - 99.78%Cor e Forma:SolidPeso molecular:785.01
