Imunologia e Inflamação
Os inibidores de imunologia e inflamação são compostos que modulam a resposta imunológica e os processos inflamatórios. Esses inibidores são cruciais para estudar os mecanismos de regulação imunológica, autoimunidade e inflamação crônica, bem como para desenvolver tratamentos para doenças inflamatórias, alergias e distúrbios relacionados ao sistema imunológico. Ao direcionar vias-chave no sistema imunológico, esses inibidores podem ajudar a reduzir respostas imunológicas excessivas ou inadequadas. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de alta qualidade para apoiar sua pesquisa em imunologia, inflamação e desenvolvimento terapêutico.
Subcategorias de "Imunologia e Inflamação"
- CCR(136 produtos)
- CXCR(149 produtos)
- Parede celular(5 produtos)
- Receptor IL(112 produtos)
- IκB/IKK(59 produtos)
- LTR(3 produtos)
- MALT(23 produtos)
- MRP(6 produtos)
- NADPH-oxidase(1 produtos)
- NF-κB(443 produtos)
- NOD(18 produtos)
- NOS(62 produtos)
- Nrf2(78 produtos)
- PGE Sintase(31 produtos)
- ROS(69 produtos)
- TGF-beta/Smad(58 produtos)
- TLR(66 produtos)
- Tiorredoxina(12 produtos)
- gp120/CD4(4 produtos)
Exibir 11 mais subcategorias
Foram encontrados 3055 produtos de "Imunologia e Inflamação"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
NoxA1ds acetate(1435893-78-9 free base)
<p>NoxA1ds acetate is a potent and selective NADPH oxidase 1 (NOX1) inhibitor (IC50 : 20 nM).</p>Fórmula:C52H92N14O17Pureza:96.92%Cor e Forma:SolidPeso molecular:1185.35Homo-PROTAC cereblon degrader 1
CAS:<p>Homo-PROTAC cereblon degrader 1 is a highly potent and efficient cereblon (CRBN) degrader with only minimal effects on IKZF1 and IKZF3.</p>Fórmula:C32H32N6O10Pureza:98.3%Cor e Forma:SolidPeso molecular:660.63CD73-IN-3
CAS:<p>CD73-IN-3 (LY-3475070) is a potent CD73 inhibitor with a 28 nM IC50, being tested in advanced cancer alone or with pembrolizumab.</p>Fórmula:C15H18N4O2Pureza:99.76%Cor e Forma:SolidPeso molecular:286.33Rhynchophylline
CAS:Rhynchophylline (Mitrinermine) is an alkaloid isolated from Crocus sativus and is widely used in anti-inflammatory and neuroprotective studies.Fórmula:C22H28N2O4Pureza:99.44% - 99.98%Cor e Forma:Red Brown Or White Fine PowderPeso molecular:384.47HS-1371
CAS:<p>HS-1371 is a novel kinase inhibitor of receptor-interacting protein kinase 3 (RIP3) with an IC50 of 20.8 nM.</p>Fórmula:C24H24N4OPureza:98%Cor e Forma:SolidPeso molecular:384.47ETHYL CAFFEATE
CAS:<p>Ethyl Caffeate (ETHYL 3,4-DIHYDROXYCINNAMATE) suppressed the differentiation of naive CD4+ T cells into Th1 in vitro.</p>Fórmula:C11H12O4Pureza:97.79%Cor e Forma:SolidPeso molecular:208.21GSK583
CAS:<p>GSK583 is a highly effective and specific RIP2 kinase inhibitor (IC50: 5 nM).</p>Fórmula:C20H19FN4O2SPureza:98.68% - 99.81%Cor e Forma:SolidPeso molecular:398.45L-Ascorbic acid 2-phosphate magnesium
CAS:<p>L-Ascorbic acid 2-phosphate magnesium is an antioxidant that promotes HGF and collagen synthesis.</p>Fórmula:C6H9O9PMgPureza:99.48% - >99.99%Cor e Forma:White PowderPeso molecular:289.53Ponesimod
CAS:<p>Ponesimod (ACT-128800) is an orally available sphingosine-1-phosphate receptor 1 (S1PR1, S1P1) agonist with potential immunomodulating activity.</p>Fórmula:C23H25ClN2O4SPureza:99.42% - 99.96%Cor e Forma:SolidPeso molecular:460.97Chlorthenoxazine
CAS:<p>Chlorthenoxazine (Chlorethylbenzmethoxazone) has anti-inflammatory activity.</p>Fórmula:C10H10ClNO2Pureza:99.64%Cor e Forma:SolidPeso molecular:211.64Isovitexin
CAS:<p>1.</p>Fórmula:C21H20O10Pureza:99.79% - 99.97%Cor e Forma:SolidPeso molecular:432.38Sulindac sodium
CAS:<p>Sulindac (sodium) (MK-231) is an NSAID used for arthritis pain, swelling, gout, and as an immunomodulator in CRC therapy.</p>Fórmula:C20H16FNaO3SCor e Forma:SolidPeso molecular:378.39MD2-IN-1
CAS:<p>MD2-IN-1 is a Myeloid differentiation protein 2 (MD2) inhibitor with a KD of 189 μM for the recombinant human MD2 (rhMD2).</p>Fórmula:C20H22O6Pureza:99.87%Cor e Forma:SolidPeso molecular:358.39Nodakenin
CAS:<p>Nodakenin ((+)-Marmesinin) is a compound with anti-allergic and anti-inflammatory activities.</p>Fórmula:C20H24O9Pureza:95.46% - 98.93%Cor e Forma:SolidPeso molecular:408.4Denosumab
CAS:<p>Denosumab is a monoclonal antibody given subcutaneously that inhibits osteoclast activity by targeting the RANK ligand</p>Fórmula:C6404H9912N1724O2004S50Pureza:95.9% (SDS-PAGE); 98.4% (SEC-HPLC) - 99.90%Cor e Forma:LiquidPeso molecular:144.71 kDaITMN4077
CAS:<p>ITMN4077 is an antiviral that inhibits Hepatitis C replication in HuH7 cells, with an EC50 of 2.131μM.</p>Fórmula:C26H40N4O8SPureza:99.78%Cor e Forma:SolidPeso molecular:568.68Phorbol 12-myristate 13-acetate
CAS:<p>Phorbol 12-myristate 13-acetate (PMA) belongs to the phorbol ester group of natural products and is an activator of PKC, SphK, and NF-κB.</p>Fórmula:C36H56O8Pureza:98.55% - >99.99%Cor e Forma:White To Off-White SolidPeso molecular:616.83STING-IN-2
CAS:STING-IN-2 (C-170) is a potent and covalent inhibitor of STING. STING-IN-2 can be used for autoinflammatory disease research.Fórmula:C15H16N2O4Pureza:98.61%Cor e Forma:SolidPeso molecular:288.3H-151
CAS:H-151 is a highly potent and selective STING antagonist.Fórmula:C17H17N3OPureza:98% - 99.97%Cor e Forma:SolidPeso molecular:279.34Balsalazide disodium dihydrate
CAS:<p>Balsalazide sodium hydrate treats mild-to-moderate ulcerative colitis; higher doses enhance remission maintenance; it's safe and effective.</p>Fórmula:C17H17N3Na2O8Pureza:98.95% - 99.49%Cor e Forma:Yellow To Orange Crystalline PowderPeso molecular:437.31SN-008
CAS:<p>SN-008 is a less active analog SN-011 which is a STING antagonist. SN-008 can be used as a negative control.</p>Fórmula:C25H19FN2O3SPureza:99.53%Cor e Forma:SolidPeso molecular:446.49Picroside II
CAS:<p>Picroside II (Vanilloyl catalpol) is the main active ingredient in iridoid glycosides.</p>Fórmula:C23H28O13Pureza:98% - 99.83%Cor e Forma:SolidPeso molecular:512.46Iguratimod
CAS:<p>Iguratimod (T614) is a COX-2 inhibitor (IC50: 20 μM), does not affect COX-1, and inhibits MIF (IC50: 6.81 μM).</p>Fórmula:C17H14N2O6SPureza:99.93%Cor e Forma:White PowderPeso molecular:374.37Diethylmaleate
CAS:<p>Diethylmaleate (Maleic acid, diethyl ester) is the diethyl ester of maleic acid and a glutathione-depleting compound that inhibits NF-kB.</p>Fórmula:C8H12O4Pureza:98%Cor e Forma:Colourless LiquidPeso molecular:172.18Gardiquimod
CAS:<p>Gardiquimod, an imidazoquinoline TLR7 agonist, inhibits HIV-1 in macrophages and PBMCs under 10μM.</p>Fórmula:C17H23N5OPureza:98.02% - 99.68%Cor e Forma:SolidPeso molecular:313.4TLR7 agonist 2
CAS:<p>TLR7 agonist 2 (TLR7-IN-1) is a specific and effective Toll-like Receptor 7 (TLR7) agonist (LEC=0.4 μM).</p>Fórmula:C17H16N6O2Pureza:99.33%Cor e Forma:SolidPeso molecular:336.35N-tert-butyl-α-Phenylnitrone
CAS:N-tert-butyl-α-Phenylnitrone ((Z)-N-benzylidene-2-Methylpropan-2-aMine oxide) inhibits COX2 catalytic activity.Fórmula:C11H15NOPureza:99.46% - 99.84%Cor e Forma:SolidPeso molecular:177.24OPHIOPOGONIN D
CAS:<p>Ophiopogonin D is a natural product,and is a CYP2J3 inducer that significantly inhibits Ang II induced NF-κB nuclear translocation.</p>Fórmula:C44H70O16Pureza:99.46% - ≥95%Cor e Forma:SolidPeso molecular:855.02Trimethylamine N-oxide dihydrate
CAS:<p>TMANO Dihydrate, from trimethylamine oxidation, stabilizes proteins against sharks' urea.</p>Fórmula:C3H13NO3Pureza:98.75%Cor e Forma:White CrystalPeso molecular:111.14Sonlicromanol
CAS:<p>KH-176 is a REDOX regulator targeting reactive oxygen species for treating mitochondrial diseases.</p>Fórmula:C19H28N2O3Cor e Forma:SolidPeso molecular:332.44Flavanomarein
CAS:<p>Flavanomarein: Antioxidant with radical scavenging, lipid peroxidation inhibition, and lipid-lowering in HepG2 cells.</p>Fórmula:C21H22O11Pureza:98.63% - 99.54%Cor e Forma:SolidPeso molecular:450.39GSK2981278
CAS:<p>GSK2981278 (ROR gama modulator 1) is a highly potent and selective inverse agonist of retinoic acid receptor-related orphan receptor gamma (ROR gamma).</p>Fórmula:C25H35NO5SPureza:99.31% - 99.67%Cor e Forma:SolidPeso molecular:461.61INH14
CAS:INH14 is a novel inhibitor of the IKKα/β-dependent TLR inflammatory response (IC50s: 8.97/3.59 μM for IKKα/IKKβ).Fórmula:C15H16N2OPureza:95.41%Cor e Forma:SolidPeso molecular:240.3sphondin
CAS:<p>Sphondin inhibits IL-1beta, reduces COX-2 and PGE(2) in A549 cells, and has anticonvulsant, anti-inflammatory, anti-proliferative properties.</p>Fórmula:C12H8O4Pureza:99.9% - ≥95%Cor e Forma:SolidPeso molecular:216.19Tectochrysin
CAS:<p>Tectochrysin: antioxidant, hinders ABCG2 transport, induces apoptosis in NSC-LC by blocking STAT3 and activating DR3/Fas.</p>Fórmula:C16H12O4Pureza:99.26%Cor e Forma:SolidPeso molecular:268.26Tenuigenin
CAS:Tenuigenin (Senegenin) is a natural product from Polygala tenuifolia used in Chinese medicine with antioxidative and anti-inflammatory activity.Fórmula:C30H45ClO6Pureza:98.9% - 99.53%Cor e Forma:SolidPeso molecular:537.13Praeruptorin A
CAS:<p>Praeruptorin A ((+)-Praeruptorin A) has the potential to inhibit migration/fusion of preosteoclasts in vitro and bone erosion in vivo by targeting calmodulin</p>Fórmula:C21H22O7Pureza:99.63% - 99.65%Cor e Forma:SolidPeso molecular:386.4Esonarimod
CAS:Esonarimod (KE-298) is an antirheumatic drug.Fórmula:C14H16O4SPureza:97.44%Cor e Forma:SolidPeso molecular:280.34TB500
CAS:<p>TB-500 is a synthesised peptide, essentially a short-chain version of the naturally occurring Thymosin Beta-4.</p>Fórmula:C38H68N10O14Pureza:99.51%Cor e Forma:SolidPeso molecular:889.01Ac2-26 acetate
<p>Ac2-26 acetate is an active N-terminal peptide of annexin A1(AnxA1).</p>Fórmula:C141H210N32O44SPureza:98%Cor e Forma:SolidPeso molecular:3089.43CORM-3
CAS:<p>CORM-3 is a carbon monoxide-releasing molecule with anti-inflammatory and cardioprotective activity.</p>Fórmula:C5H4ClNO5RuPureza:98%Cor e Forma:SolidPeso molecular:294.61Dexamethasone Sodium Phosphate
CAS:<p>Dexamethasone Sodium Phosphate (Dexadreson) is a powerful anti-inflammatory and immunosuppressant synthetic glucocorticoid.</p>Fórmula:C22H30FO8P·2NaPureza:99.01% - 99.81%Cor e Forma:SolidPeso molecular:516.4CU-CPT9b
CAS:<p>CU-CPT9b (TLR8-specific antagonist 1) is an antagonist of toll-like receptor 8 (TLR8; Kd = 21 nM).</p>Fórmula:C16H13NO2Pureza:98.1%Cor e Forma:SolidPeso molecular:251.28Adelmidrol
CAS:Adelmidrol is an anti-inflammatory ethanolamide derivative of azelaic acid.Fórmula:C13H26N2O4Pureza:99.35% - 99.73%Cor e Forma:SolidPeso molecular:274.36Brincidofovir
CAS:Brincidofovir (HDP-CDV) is an orally active, lipophilic form of cidofovir.Fórmula:C27H52N3O7PPureza:98% - 99.62%Cor e Forma:SolidPeso molecular:561.69hPGDS-IN-1
CAS:<p>hPGDS-IN-1 is a hPGDS inhibitor.</p>Fórmula:C22H20N6O3Pureza:99.77% - >99.99%Cor e Forma:SolidPeso molecular:416.43Sinomenine
CAS:<p>Sinomenine (Kukoline) is a pure alkaloid isolated from the Sinomenium acutum, is utilized in the treatment of rheumatism and arthritis.</p>Fórmula:C19H23NO4Pureza:99.02% - 99.73%Cor e Forma:White PowderPeso molecular:329.39CTX-0294885
CAS:CTX-0294885, a bisanilino pyrimidine, inhibits many kinases; used for Sepharose-based kinase capture.Fórmula:C22H24ClN7OPureza:98.73% - ≥95%Cor e Forma:SolidPeso molecular:437.93ISOGINKGETIN
CAS:<p>ISOGINKGETIN (4',4'''-Dimethylamentoflavone), a compound derived from the leaves of Ginkgo biloba, to up-regulate adiponectin secretion.</p>Fórmula:C32H22O10Pureza:98% - 99.72%Cor e Forma:SolidPeso molecular:566.51AZD3264
CAS:<p>AZD3264 is a new type IKK2 inhibitor.</p>Fórmula:C21H23N5O4SPureza:98.98% - 99.17%Cor e Forma:SolidPeso molecular:441.5
