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Transportador de Membranas/Canal Iónico

Transportador de Membranas/Canal Iónico

Os inibidores de transportadores de membrana e canais iônicos são compostos que bloqueiam a função de proteínas responsáveis pelo transporte de íons, nutrientes e outras moléculas através das membranas celulares. Esses inibidores são cruciais para o estudo da regulação da homeostase celular, transdução de sinais e neurotransmissão. Os inibidores de transportadores de membrana e canais iônicos também são importantes no desenvolvimento de tratamentos para distúrbios como epilepsia, doenças cardiovasculares e síndromes metabólicas. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de alta qualidade de transportadores de membrana e canais iônicos para apoiar sua pesquisa em fisiologia, neurociência e farmacologia.

Subcategorias de "Transportador de Membranas/Canal Iónico"

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Foram encontrados 2290 produtos de "Transportador de Membranas/Canal Iónico"

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  • Tizolemide
    Targetmol
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    Tizolemide

    CAS:
    <p>Tizolemide, a sulfonamide diuretic compound with alkaline properties, is cleared through the tubular transport system. It induces changes in the passive transport components across the basolateral membrane of isolated frog skin.</p>
    Fórmula:C11H14ClN3O3S2
    Cor e Forma:Solid
    Peso molecular:335.83

    Ref: TM-T201590

  • Logotipo do CymitQuimica
    Targetmol
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    PDE1-IN-4

    <p>PDE1-IN-4: inhibits PDE1C/A/B with IC50s 10/145/354 nM, may help study idiopathic pulmonary fibrosis.</p>
    Fórmula:C33H33N3O4
    Cor e Forma:Solid
    Peso molecular:535.63

    Ref: TM-T63776

  • Desmethylflunitrazepam
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    Desmethylflunitrazepam

    CAS:
    <p>Desmethylflunitrazepam (Norflunitrazepam) is a benzodiazepine derivative and an active metabolite of Flunitrazepam.</p>
    Fórmula:C15H10FN3O3
    Cor e Forma:Solid
    Peso molecular:299.26

    Ref: TM-T201723

  • Logotipo do CymitQuimica
    Targetmol
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    P2X receptor-1

    <p>P2X receptor-1 is a potential inhibitor of P2X receptor for the treatment of pain and inflammation.</p>
    Fórmula:C14H14ClN3O3S2
    Cor e Forma:Solid
    Peso molecular:371.86

    Ref: TM-T61490

  • SOAT-IN-1
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    SOAT-IN-1

    CAS:
    SOAT-IN-1 (compound 40) is a potent and selective inhibitor targeting the sodium-dependent organic anion transporter (SOAT), exhibiting IC50 values of 1.6 µM for SOAT and 14.3 µM for NTCP.
    Fórmula:C20H16ClN3O6S
    Cor e Forma:Solid
    Peso molecular:461.88

    Ref: TM-T201002

  • 5-O-Desmethyl donepezil
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    5-O-Desmethyl donepezil

    CAS:
    <p>5-O-Desmethyl donepezil is a metabolite of Donepezil that acts as an inhibitor of hERG channels, with an IC50 of 1.5 μM.</p>
    Fórmula:C23H27NO3
    Cor e Forma:Solid
    Peso molecular:365.465

    Ref: TM-T206238

  • N-Depropylpropafenone
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    N-Depropylpropafenone

    CAS:
    <p>N-Depropylpropafenone, an active metabolite of Propafenone, is produced through the metabolism by the CYP450 enzyme system (primarily CYP2D6). It functions by blocking sodium ion channels, thereby delaying the depolarization process in myocardial cells and exhibiting antiarrhythmic properties.</p>
    Fórmula:C18H21NO3
    Cor e Forma:Solid
    Peso molecular:299.36

    Ref: TM-T201563

  • ICA-105665
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    ICA-105665

    CAS:
    ICA-105665 is an orally active Kv7.2/7.3/7.5 channel opener, CNS-penetrant with antiseizure effects, and low hepatocyte cytotoxicity.
    Fórmula:C19H15F2N3O2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:355.34

    Ref: TM-T11606

  • KCC2 Modulator-2
    Targetmol
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    KCC2 Modulator-2

    CAS:
    <p>KCC2 Modulator-2 (example 53) is a regulator of KCC2 with an EC50 of 0.215 μM. It is used in the research of neurological diseases.</p>
    Fórmula:C35H45N5O3
    Cor e Forma:Solid
    Peso molecular:583.76

    Ref: TM-T201666

  • GNE-616
    Targetmol
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    GNE-616

    CAS:
    <p>GNE-616: a potent, stable, oral Nav1.7 inhibitor; Ki: 0.79 nM, Kd: 0.38 nM; for chronic pain.</p>
    Fórmula:C24H23F4N5O3S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:537.53

    Ref: TM-T11439

  • Tuclazepam
    Targetmol
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    Tuclazepam

    CAS:
    <p>Tuclazepam (KC 1956) is a derivative of the benzodiazepine class of drugs, exhibiting anti-anxiety and sedative properties.</p>
    Fórmula:C17H16Cl2N2O
    Cor e Forma:Solid
    Peso molecular:335.23

    Ref: TM-T201570

  • (RS)-AMPA hydrobromide
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    (RS)-AMPA hydrobromide

    CAS:
    AMPAR agonist
    Fórmula:C7H11BrN2O4
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:267.08

    Ref: TM-T23267

  • SC-435 mesylate
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    SC-435 mesylate

    CAS:
    <p>SC-435 is an ileal apical sodium co-dependent bile acid transporter (ASBT). SC-435 inhibits plasma cholesterol.</p>
    Fórmula:C37H59N3O7S2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:722.01

    Ref: TM-T28700

  • Suloctidil HCl
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    Suloctidil HCl

    CAS:
    <p>Suloctidil HCl is a peripheral vascular dilator.</p>
    Fórmula:C20H36ClNOS
    Cor e Forma:Solid
    Peso molecular:374.02

    Ref: TM-T0712L

  • TRPC5-IN-4
    Targetmol
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    TRPC5-IN-4

    CAS:
    <p>TRPC5-IN-4: Potent, safe inhibitor; IC50 14.07 nM (TRPC5), 65 nM (TRPC4); non-toxic to liver/kidney cells; for CKD research.</p>
    Fórmula:C18H11ClF4N4O3
    Cor e Forma:Solid
    Peso molecular:442.75

    Ref: TM-T62589

  • P-gp/BCRP-IN-1
    Targetmol
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    P-gp/BCRP-IN-1

    CAS:
    <p>P-gp/BCRP-IN-1, safe and oral, inhibits P-gp/BCRP transporters, enhancing Paclitaxel bioavailability.</p>
    Fórmula:C27H25ClN4O3
    Cor e Forma:Solid
    Peso molecular:488.97

    Ref: TM-T63267

  • Logotipo do CymitQuimica
    Targetmol
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    DAD

    <p>DAD is an ion channel blocker (blocks voltage-gated potassium channels) and is a third generation photoelectric switch that responds to visible light.</p>
    Fórmula:C26H40N6O
    Cor e Forma:Solid
    Peso molecular:452.64

    Ref: TM-T62770

  • Logotipo do CymitQuimica
    Targetmol
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    Cav 3.2 inhibitor 1

    <p>Cav 3.2 inhibitor 1 targets T-type calcium channels, weakly binds D2 receptors, and aids physical and visceral pain research.</p>
    Fórmula:C32H39N3O
    Cor e Forma:Solid
    Peso molecular:481.67

    Ref: TM-T63186

  • KV1.3-IN-2
    Targetmol
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    KV1.3-IN-2

    CAS:
    <p>KV1.3-IN-2 (Compound I) selectively inhibits the kv1.3 potassium channel without affecting the hERG channel. It is applicable in research related to immune-associated diseases such as psoriasis, rheumatoid arthritis, and systemic lupus erythematosus.</p>
    Fórmula:C16H23ClN2O4
    Cor e Forma:Solid
    Peso molecular:342.818

    Ref: TM-T205655

  • TP003
    Targetmol
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    TP003

    CAS:
    <p>TP003 is a novel non-selective GABAA receptor benzodiazepine site agonist with affinity for α1β2gam2, α2β3gam2, α3β3gam2, α5β2gam2, EC50 of 20.3, 10.6, 3.24, 5.</p>
    Fórmula:C23H16F3N3O
    Pureza:99.17%
    Cor e Forma:Solid
    Peso molecular:407.39

    Ref: TM-T23466