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Transportador de Membranas/Canal Iónico

Transportador de Membranas/Canal Iónico

Os inibidores de transportadores de membrana e canais iônicos são compostos que bloqueiam a função de proteínas responsáveis pelo transporte de íons, nutrientes e outras moléculas através das membranas celulares. Esses inibidores são cruciais para o estudo da regulação da homeostase celular, transdução de sinais e neurotransmissão. Os inibidores de transportadores de membrana e canais iônicos também são importantes no desenvolvimento de tratamentos para distúrbios como epilepsia, doenças cardiovasculares e síndromes metabólicas. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de alta qualidade de transportadores de membrana e canais iônicos para apoiar sua pesquisa em fisiologia, neurociência e farmacologia.

Subcategorias de "Transportador de Membranas/Canal Iónico"

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Foram encontrados 2277 produtos de "Transportador de Membranas/Canal Iónico"

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  • ATPase-IN-5
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    ATPase-IN-5

    CAS:
    <p>ATPase-IN-5 (Compound 11) is an antifungal Pma1p (H+ -ATPase) inhibitor (IC50 = 12.7 μM) that inhibits the growth of Candida albicans and Saccharomyces cerevisiae.</p>
    Fórmula:C10H10N4O3S
    Pureza:99.19%
    Cor e Forma:Solid
    Peso molecular:266.28

    Ref: TM-T204943

  • Logotipo do CymitQuimica
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    PDE1-IN-4

    <p>PDE1-IN-4: inhibits PDE1C/A/B with IC50s 10/145/354 nM, may help study idiopathic pulmonary fibrosis.</p>
    Fórmula:C33H33N3O4
    Cor e Forma:Solid
    Peso molecular:535.63

    Ref: TM-T63776

  • Logotipo do CymitQuimica
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    P2X receptor-1

    <p>P2X receptor-1 is a potential inhibitor of P2X receptor for the treatment of pain and inflammation.</p>
    Fórmula:C14H14ClN3O3S2
    Cor e Forma:Solid
    Peso molecular:371.86

    Ref: TM-T61490

  • 5-O-Desmethyl donepezil
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    5-O-Desmethyl donepezil

    CAS:
    <p>5-O-Desmethyl donepezil is a metabolite of Donepezil that acts as an inhibitor of hERG channels, with an IC50 of 1.5 μM.</p>
    Fórmula:C23H27NO3
    Cor e Forma:Solid
    Peso molecular:365.465

    Ref: TM-T206238

  • ICA-105665
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    ICA-105665

    CAS:
    <p>ICA-105665 is an orally active Kv7.2/7.3/7.5 channel opener, CNS-penetrant with antiseizure effects, and low hepatocyte cytotoxicity.</p>
    Fórmula:C19H15F2N3O2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:355.34

    Ref: TM-T11606

  • GNE-616
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    GNE-616

    CAS:
    <p>GNE-616: a potent, stable, oral Nav1.7 inhibitor; Ki: 0.79 nM, Kd: 0.38 nM; for chronic pain.</p>
    Fórmula:C24H23F4N5O3S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:537.53

    Ref: TM-T11439

  • (RS)-AMPA hydrobromide
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    (RS)-AMPA hydrobromide

    CAS:
    AMPAR agonist
    Fórmula:C7H11BrN2O4
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:267.08

    Ref: TM-T23267

  • KV1.3-IN-2
    Targetmol
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    KV1.3-IN-2

    CAS:
    <p>KV1.3-IN-2 (Compound I) selectively inhibits the kv1.3 potassium channel without affecting the hERG channel. It is applicable in research related to immune-associated diseases such as psoriasis, rheumatoid arthritis, and systemic lupus erythematosus.</p>
    Fórmula:C16H23ClN2O4
    Cor e Forma:Solid
    Peso molecular:342.818

    Ref: TM-T205655

  • Opakalim
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    Opakalim

    CAS:
    <p>Opakalim is an activator of potassium channels (potassium channel) and exhibits anticonvulsant activity.</p>
    Fórmula:C18H22F2N4O
    Cor e Forma:Solid
    Peso molecular:348.39

    Ref: TM-T206117

  • Logotipo do CymitQuimica
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    WS-898

    <p>WS-898 boosts paclitaxel efficacy in resistant cells by inhibiting ABCB1; IC50: SW620/Ad300 - 5.0 nM, KB-C2 - 3.67 nM, HEK293/ABCB1 - 3.68 nM.</p>
    Fórmula:C33H25N7OS
    Cor e Forma:Solid
    Peso molecular:567.66

    Ref: TM-T64016

  • Blixeprodil
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    Blixeprodil

    CAS:
    <p>Blixeprodil (GM-1020) is an orally active NMDA receptor antagonist with an affinity of Ki = 3.25 µM in rat cortical tissue. It inhibits NR1/2A-NMDAR-mediated currents in HEK293 cells with an IC50 of 1.192 µM. Blixeprodil demonstrates antidepressant effects in rat models and exhibits blood-brain barrier permeability.</p>
    Fórmula:C13H16FNO
    Cor e Forma:Solid
    Peso molecular:221.271

    Ref: TM-T206599

  • Logotipo do CymitQuimica
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    IAA65

    CAS:
    <p>IAA65 is a potent inhibitor of T-type calcium channels, exhibiting an IC50 value of 18.9 μM, and holds potential for use in epilepsy research [1].</p>
    Fórmula:C16H13F6NO2
    Cor e Forma:Solid
    Peso molecular:365.27

    Ref: TM-T61393

  • Logotipo do CymitQuimica
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    VU0463271 quarterhydrate

    <p>VU0463271 quarterhydrate is a potent KCC2 antagonist, with an IC 50 of 61 nM [1].</p>
    Fórmula:C19H20N4O2S2
    Cor e Forma:Solid
    Peso molecular:387

    Ref: TM-T61725

  • V-ATPase-IN-1
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    V-ATPase-IN-1

    CAS:
    <p>V-ATPase-IN-1 (Compound 3b-03) is an inhibitor of Vacuolar-type H+-ATPases (V-ATPase), exhibiting an inhibition constant (IC50) of 194.80 μM and effectively targeting the V-ATPase subunit A with a dissociation constant (Kd) of 0.803 μM. This compound demonstrates insecticidal activity against M. separata (LC50 = 2.64 mM), aiding in the development of chemical insecticides.</p>
    Fórmula:C21H20ClNO2
    Cor e Forma:Solid
    Peso molecular:353.84

    Ref: TM-T200467

  • (S)-Albuterol
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    (S)-Albuterol

    CAS:
    <p>(S)-Albuterol functions as a muscarinic receptor and phospholipase C activator, enhancing the intracellular free calcium concentration in airway smooth muscle cells.</p>
    Fórmula:C13H21NO3
    Cor e Forma:Solid
    Peso molecular:239.311

    Ref: TM-T206288

  • Lubeluzole dihydrochloride
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    Lubeluzole dihydrochloride

    CAS:
    <p>Lubeluzole (dihydrochloride) acts as a neuroprotective agent by blocking neuronal voltage-gated sodium channels and also affects cardiac sodium channels, exhibiting both tonic and blocking effects. This compound is considered promising in the research of antiarrhythmic agents.</p>
    Fórmula:C22H27Cl2F2N3O2S
    Cor e Forma:Solid
    Peso molecular:506.44

    Ref: TM-T200178

  • Kv7.2/Kv7.3 activator-1
    Targetmol
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    Kv7.2/Kv7.3 activator-1

    CAS:
    <p>Kv7.2/Kv7.3 Activator-1 (compound 517) serves as a powerful activator of the Kv7.2/Kv7.3 channels, exhibiting an EC50 value of less than 1 µM. It holds potential for use in neurological disease research.</p>
    Fórmula:C19H22F2N4O
    Cor e Forma:Solid
    Peso molecular:360.40

    Ref: TM-T89880

  • PF-05661014
    Targetmol
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    PF-05661014

    CAS:
    <p>PF-05661014, a demethylated analogue of PF-06526290, selectively inhibits Nav1.3 and Nav1.7 currents by stabilizing the inactivated state through interaction with the D4 VSD. This compound is utilized in research focused on sodium channel modulation.</p>
    Fórmula:C17H16N4O3S2
    Cor e Forma:Solid
    Peso molecular:388.46

    Ref: TM-T89885

  • CFTR corrector 16
    Targetmol
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    CFTR corrector 16

    CAS:
    <p>CFTRcorrector 16 (Compound 39) is a corrector of the cystic fibrosis transmembrane conductance regulator (CFTR), utilized in the research of cystic fibrosis disease.</p>
    Fórmula:C27H26ClN5O2S
    Cor e Forma:Solid
    Peso molecular:520.05

    Ref: TM-T200113

  • SP100030 analogue 1
    Targetmol
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    SP100030 analogue 1

    CAS:
    SP100030 analogue 1 (compound 11) is a selective transcription activation (SITA) inhibitor within the SP100030 class, capable of inhibiting XPO1-dependent upregulation of IL2 in a Jurkat-based IL2-Luc reporter assay, with an EC50 of 137 nM.
    Fórmula:C13H5ClF7N3O
    Cor e Forma:Solid
    Peso molecular:387.64

    Ref: TM-T89990