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Transportador de Membranas/Canal Iónico

Transportador de Membranas/Canal Iónico

Os inibidores de transportadores de membrana e canais iônicos são compostos que bloqueiam a função de proteínas responsáveis pelo transporte de íons, nutrientes e outras moléculas através das membranas celulares. Esses inibidores são cruciais para o estudo da regulação da homeostase celular, transdução de sinais e neurotransmissão. Os inibidores de transportadores de membrana e canais iônicos também são importantes no desenvolvimento de tratamentos para distúrbios como epilepsia, doenças cardiovasculares e síndromes metabólicas. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de alta qualidade de transportadores de membrana e canais iônicos para apoiar sua pesquisa em fisiologia, neurociência e farmacologia.

Subcategorias de "Transportador de Membranas/Canal Iónico"

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Foram encontrados 2277 produtos de "Transportador de Membranas/Canal Iónico"

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  • CFTR corrector 15
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    CFTR corrector 15

    CAS:
    <p>CFTR Corrector 15 (Compound 4172) serves as a corrector for cystic fibrosis transmembrane conductance regulator (CFTR). When used in combination with VX-809, it addresses the folding defects of F508del-CFTR. CFTR Corrector 15 is also applicable in the research of cystic fibrosis.</p>
    Fórmula:C24H22ClN5O2S
    Cor e Forma:Solid
    Peso molecular:479.98

    Ref: TM-T89966

  • (2S,3S,11bR)-Dihydrotetrabenazine
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    (2S,3S,11bR)-Dihydrotetrabenazine

    CAS:
    <p>(2S,3S,11bR)-Dihydrotetrabenazine ((2S,3S,11bR)-DHTBZ) is a highly selective inhibitor of vesicular monoamine transporter 2 (VMAT2) with a Ki value of 593 nM. It suppresses the vesicular transport of monoamine neurotransmitters, such as dopamine and serotonin, leading to reduced release into the synaptic cleft. This compound holds potential for research in Huntington's disease and other hyperkinetic movement disorders.</p>
    Fórmula:C19H29NO3
    Cor e Forma:Solid
    Peso molecular:319.44

    Ref: TM-T207440

  • S 0960
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    S 0960

    CAS:
    <p>S 0960 is a dimeric bile acid analogue, a specific inhibitor of the sodium-dependent bile salt transporter in the ileum, used in metabolic disease research.</p>
    Fórmula:C48H79NO8
    Pureza:99.32% - >99.99%
    Cor e Forma:Solid
    Peso molecular:798.14

    Ref: TM-T70688

  • PF-06462894
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    PF-06462894

    CAS:
    PF-06462894: morpholinopyrimidone, mGlu5 antagonist (Ki=6nM), no immune activation in mouse model.
    Fórmula:C18H23N3O3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:329.39

    Ref: TM-T28372

  • 2-PPA
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    2-PPA

    CAS:
    2-PPA serves as a selective TMEM175 inhibitor (IC 50 =32 μM), primarily influencing lysosomal activity. Through acute inhibition of TMEM175, 2-PPA enhances lysosomal macromolecular catabolism, which in turn boosts macrophage activity and other digestive processes. This compound holds significance in Parkinson's disease research.
    Fórmula:C11H10N2
    Cor e Forma:Solid
    Peso molecular:170.21

    Ref: TM-T89916

  • Caramboxin
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    Caramboxin

    CAS:
    <p>Caramboxin, a neurotoxin, can induce acute kidney injury.</p>
    Fórmula:C11H13NO6
    Cor e Forma:Solid
    Peso molecular:255.22

    Ref: TM-T201088

  • Dehydroindapamide
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    Dehydroindapamide

    CAS:
    <p>Dehydroindapamide, an indole form of Indapamide, is utilized to quantify the turnover rate of Indapamide in CYP3A4, which is approximately 10 times higher than that of Indoline, with slightly enhanced affinity for CYP3A4.</p>
    Fórmula:C16H14ClN3O3S
    Cor e Forma:Solid
    Peso molecular:363.82

    Ref: TM-T200811

  • Perfluoroheptanesulfonic acid
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    Perfluoroheptanesulfonic acid

    CAS:
    <p>Perfluoroheptanesulfonic acid (1-Perfluoroheptanesulfonic acid; Perfluoroheptanesulphonic acid) is a perfluoroalkyl substance (PFAS). This compound has been detected in landfill leachate and has been shown to induce deformities in zebrafish larvae (EC50=168.1 μM). Exposure to PFHpS in fetuses can lead to reduced birth weight.</p>
    Fórmula:C7HF15O3S
    Cor e Forma:Solid
    Peso molecular:450.12

    Ref: TM-T200995

  • ZK 93426 hydrochloride
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    ZK 93426 hydrochloride

    CAS:
    <p>benzodiazepine receptor antagonist,competitive</p>
    Fórmula:C18H21ClN2O3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:348.82

    Ref: TM-T23562

  • CAD204520
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    CAD204520

    CAS:
    <p>CAD204520 functions as an inhibitor of SERCA (IC50 = 0.34 μM), specifically targeting mutations in the wild-type NOTCH1 protein associated with T-cell acute lymphoblastic leukemia (T-ALL) and mantle cell lymphoma (MCL).</p>
    Fórmula:C23H32F3N3O2
    Cor e Forma:Solid
    Peso molecular:439.51

    Ref: TM-T200097

  • AP-6
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    AP-6

    CAS:
    AP-6, a selective TMEM175 inhibitor, enhances lysosomal macromolecular catabolism by acutely inhibiting TMEM175, thus speeding up macrophage and other digestive activities. This compound holds potential for use in Parkinson's disease research due to its role in modulating lysosomal function.
    Fórmula:C16H14N4
    Cor e Forma:Solid
    Peso molecular:262.31

    Ref: TM-T200356

  • AN-988
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    AN-988

    CAS:
    <p>AN-988 (compound 6) is a covalent CRM1 inhibitor.</p>
    Fórmula:C22H22N2O4S
    Cor e Forma:Solid
    Peso molecular:410.49

    Ref: TM-T200424

  • Fletazepam
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    Fletazepam

    CAS:
    <p>Fletazepam, a benzodiazepine derivative, exhibits sedative, anti-anxiety, and muscle-relaxant properties. It is utilized in neurological research.</p>
    Fórmula:C17H13ClF4N2
    Cor e Forma:Solid
    Peso molecular:356.74

    Ref: TM-T201147

  • SOAT-IN-1
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    SOAT-IN-1

    CAS:
    <p>SOAT-IN-1 (compound 40) is a potent and selective inhibitor targeting the sodium-dependent organic anion transporter (SOAT), exhibiting IC50 values of 1.6 µM for SOAT and 14.3 µM for NTCP.</p>
    Fórmula:C20H16ClN3O6S
    Cor e Forma:Solid
    Peso molecular:461.88

    Ref: TM-T201002

  • LY 215490
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    LY 215490

    CAS:
    <p>LY 215490 is a selective AMPA receptor antagonist with neuroprotective properties in rat ischemia.</p>
    Fórmula:C13H21N5O2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:279.34

    Ref: TM-T27897

  • Lorajmine
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    Lorajmine

    CAS:
    <p>Lorajmine, a monochloroacetyl derivative of ajmaline, is a class Ia antiarrhythmic agent that is rapidly hydrolyzed to ajmaline by plasma and tissue esterases.</p>
    Fórmula:C22H27ClN2O3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:402.91

    Ref: TM-T25755

  • PD-217014
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    PD-217014

    CAS:
    <p>PD-217014 is an α2δ ligand that exhibits visceral analgesic activity and can suppress visceral hypersensitivity. Its antihyperalgesic effects are dose-dependent.</p>
    Fórmula:C10H17NO2
    Cor e Forma:Solid
    Peso molecular:183.25

    Ref: TM-T200642

  • SDZ 220-040
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    SDZ 220-040

    CAS:
    <p>SDZ 220-040 是一种选择性哺乳动物 NMDA 受体拮抗剂，可诱导根系生长的部分无重力模式 。</p>
    Fórmula:C16H16Cl2NO6P
    Pureza:98.13%
    Cor e Forma:Solid
    Peso molecular:420.18

    Ref: TM-T23344

  • Suzetrigine
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    Suzetrigine

    CAS:
    <p>Suzetrigine (VX-548) is an oral NaV1.8 inhibitor with analgesic properties for acute pain research.</p>
    Fórmula:C21H20F5N3O4
    Pureza:98.08% - 99.27%
    Cor e Forma:Solid
    Peso molecular:473.39

    Ref: TM-T69552

  • Odevixibat
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    Odevixibat

    CAS:
    <p>Odevixibat (A4250) is a selective oral inhibitor for ileal bile acid transport, potentially treating primary biliary cirrhosis.</p>
    Fórmula:C37H48N4O8S2
    Pureza:99.53% - 99.83%
    Cor e Forma:Solid
    Peso molecular:740.93

    Ref: TM-T16376