Transportador de Membranas/Canal Iónico
Os inibidores de transportadores de membrana e canais iônicos são compostos que bloqueiam a função de proteínas responsáveis pelo transporte de íons, nutrientes e outras moléculas através das membranas celulares. Esses inibidores são cruciais para o estudo da regulação da homeostase celular, transdução de sinais e neurotransmissão. Os inibidores de transportadores de membrana e canais iônicos também são importantes no desenvolvimento de tratamentos para distúrbios como epilepsia, doenças cardiovasculares e síndromes metabólicas. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de alta qualidade de transportadores de membrana e canais iônicos para apoiar sua pesquisa em fisiologia, neurociência e farmacologia.
Subcategorias de "Transportador de Membranas/Canal Iónico"
- ABC(3 produtos)
- ATPase(101 produtos)
- Receptor de adiponectina(5 produtos)
- CFTR(65 produtos)
- Receptor CGRP(54 produtos)
- Canais de Cálcio(541 produtos)
- Canal de cloreto(53 produtos)
- Receptor GABA(365 produtos)
- Transportador de monoamina(30 produtos)
- Transportador de monocarboxilato(18 produtos)
- NKCC(2 produtos)
- NPC1L1(3 produtos)
- Cotransportador Na-K-Cl(10 produtos)
- OAT(32 produtos)
- OCT(7 produtos)
- P-gp(55 produtos)
- Canal de Potássio(280 produtos)
- Bomba de prótons(42 produtos)
- SGLT(31 produtos)
- Canal de Sódio(209 produtos)
- Canal TRP/TRPV(96 produtos)
Exibir 13 mais subcategorias
Foram encontrados 2521 produtos de "Transportador de Membranas/Canal Iónico"
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Kv7.2/Kv7.3 modulator-1
CAS:Kv7.2/Kv7.3 modulator-1 (compound 6a) acts as a modulator for Kv7.2/Kv7.3 channels, with a pEC50 value of 7.96 for opening these channels. Kv7.2/Kv7.3 modulator-1 is applicable in research related to epilepsy, depression, brain injury, and pain.Fórmula:C20H21F4N3O3Cor e Forma:SolidPeso molecular:427.393Caramboxin
CAS:Caramboxin, a neurotoxin, can induce acute kidney injury.Fórmula:C11H13NO6Cor e Forma:SolidPeso molecular:255.22DAD dichloride
DAD dichloride is a 3rd-gen photoelectric switch, blocks K+ channels, and helps in visual function research.Fórmula:C26H42Cl2N6OCor e Forma:SolidPeso molecular:525.56Dehydroindapamide
CAS:Dehydroindapamide, an indole form of Indapamide, is utilized to quantify the turnover rate of Indapamide in CYP3A4, which is approximately 10 times higher than that of Indoline, with slightly enhanced affinity for CYP3A4.Fórmula:C16H14ClN3O3SCor e Forma:SolidPeso molecular:363.82TRPA1 Antagonist 1
CAS:TRPA1 Antagonist 1 is an antagonist of TRPA1(IC50: 8 nM) and is a methylene phosphate prodrug which converts to its active parent drug.Fórmula:C24H20F6N5Na2O7PSPureza:98%Cor e Forma:SolidPeso molecular:713.45pan-HCN-IN-1
CAS:Pan-HCN-IN-1 (Compound J&J12e) is an inhibitor of the hyperpolarization-activated and cyclic-nucleotide-gated 1 (HCN1) ion channel, with an IC50 of 58 nM. Pan-HCN-IN-1 reduces the voltage sag response and enhances EPSP summation in ex vivo rat brain slices [1].Fórmula:C23H37N3O2Cor e Forma:SolidPeso molecular:387.56ABCA1 inducer 2
CAS:ABCA1 inducer 2 is a non-lipogenic inducer of ABCA1. It increases the expression of ABCA1 by targeting the LXR pathway, thereby reducing lipid accumulation induced by ox-LDL and inhibiting foam cell formation. ABCA1 inducer 2 holds potential as an anti-atherosclerotic agent.Fórmula:C16H11BrN2OCor e Forma:SolidPeso molecular:327.175Perfluoroheptanesulfonic acid
CAS:Perfluoroheptanesulfonic acid (1-Perfluoroheptanesulfonic acid; Perfluoroheptanesulphonic acid) is a perfluoroalkyl substance (PFAS). This compound has been detected in landfill leachate and has been shown to induce deformities in zebrafish larvae (EC50=168.1 μM). Exposure to PFHpS in fetuses can lead to reduced birth weight.Fórmula:C7HF15O3SCor e Forma:SolidPeso molecular:450.12ZK 93426 hydrochloride
CAS:benzodiazepine receptor antagonist,competitiveFórmula:C18H21ClN2O3Pureza:98%Cor e Forma:SolidPeso molecular:348.82CAD204520
CAS:CAD204520 functions as an inhibitor of SERCA (IC50 = 0.34 μM), specifically targeting mutations in the wild-type NOTCH1 protein associated with T-cell acute lymphoblastic leukemia (T-ALL) and mantle cell lymphoma (MCL).Fórmula:C23H32F3N3O2Cor e Forma:SolidPeso molecular:439.51AP-6
CAS:AP-6, a selective TMEM175 inhibitor, enhances lysosomal macromolecular catabolism by acutely inhibiting TMEM175, thus speeding up macrophage and other digestive activities. This compound holds potential for use in Parkinson's disease research due to its role in modulating lysosomal function.Fórmula:C16H14N4Cor e Forma:SolidPeso molecular:262.31AN-988
CAS:AN-988 (compound 6) is a covalent CRM1 inhibitor.Fórmula:C22H22N2O4SCor e Forma:SolidPeso molecular:410.49Suloctidil HCl
CAS:Suloctidil HCl is a peripheral vascular dilator.Fórmula:C20H36ClNOSCor e Forma:SolidPeso molecular:374.02Fletazepam
CAS:Fletazepam, a benzodiazepine derivative, exhibits sedative, anti-anxiety, and muscle-relaxant properties. It is utilized in neurological research.Fórmula:C17H13ClF4N2Cor e Forma:SolidPeso molecular:356.74MSK-195
CAS:MSK-195 is an effective TRPV1 agonist.Fórmula:C28H40N2O5Pureza:98%Cor e Forma:SolidPeso molecular:484.63P-gp inhibitor 2
CAS:Potent P-gp inhibitor 2 reverses Doxorubicin resistance in colorectal carcinoma cells with IC50 of 0.22 µM.Fórmula:C29H26N2O6Cor e Forma:SolidPeso molecular:498.53Dehydelone
CAS:Dehydelone(KOS-1584, R-1645, SK-10088) is a microtubule stabilizer that may be used in the treatment of non-small cell lung cancer.Fórmula:C27H39NO5SCor e Forma:SolidPeso molecular:489.67SOAT-IN-1
CAS:SOAT-IN-1 (compound 40) is a potent and selective inhibitor targeting the sodium-dependent organic anion transporter (SOAT), exhibiting IC50 values of 1.6 µM for SOAT and 14.3 µM for NTCP.Fórmula:C20H16ClN3O6SCor e Forma:SolidPeso molecular:461.88(+)-Tetrabenazine
CAS:(+)-Tetrabenazine ((3R,11bR)-Tetrabenazine) is a reversible vesicular monoamine transporter 2 (VMAT-2) inhibitor, inhibits transport by VMAT2 with 10-foldFórmula:C19H27NO3Pureza:98.69%Cor e Forma:SolidPeso molecular:317.42Odevixibat
CAS:Odevixibat (A4250) is a selective oral inhibitor for ileal bile acid transport, potentially treating primary biliary cirrhosis.Fórmula:C37H48N4O8S2Pureza:99.53% - 99.83%Cor e Forma:SolidPeso molecular:740.93
