PPAR
Os receptores ativados por proliferadores de peroxissomas (PPARs) são um grupo de proteínas receptoras nucleares que funcionam como fatores de transcrição, regulando a expressão de genes envolvidos no metabolismo, particularmente no armazenamento de ácidos graxos e no metabolismo da glicose. Inibidores de PPAR são ferramentas importantes para o estudo de distúrbios metabólicos como diabetes, obesidade e doenças cardiovasculares. Esses inibidores podem modular o metabolismo lipídico, a sensibilidade à insulina e a inflamação, tornando-os valiosos na pesquisa terapêutica. Na CymitQuimica, oferecemos uma gama de inibidores de PPAR para apoiar sua pesquisa em doenças metabólicas, endocrinologia e desenvolvimento de medicamentos.
Foram encontrados 170 produtos de "PPAR"
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NSC-87877
CAS:NSC-87877 inhibits Shp2 (IC50=0.318μM), Shp1 (IC50=0.355μM), and DUSP26 phosphatases.Fórmula:C19H13N3O7S2Pureza:97.35%Cor e Forma:SolidPeso molecular:459.45Pioglitazone
CAS:Pioglitazone (U 72107) is a selective and oral PPARγ agonist with EC50 of 0.93 and 0.99 μM on human and mouse PPARγ, respectively . High-Quality, Low-Cost!Fórmula:C19H20N2O3SPureza:95% - 99.57%Cor e Forma:White PowderPeso molecular:356.44Magnolol
CAS:Magnolol (5,5'-Diallyl-2,2'-biphenyldiol) is a dual agonist of RXRα( EC50=10.4 μM) and PPARγ(EC50=17.7 μM). It blocks TNF-α-induced NF-KB activation.Fórmula:C18H18O2Pureza:99.49% - 99.98%Cor e Forma:A Bioactive Compound Found In The Bark Of The Houpu MagnoliaPeso molecular:266.33Clofibric acid
CAS:Clofibric acid (Chlorofibrinic acid) is an antilipemic agent that is the biologically active metabolite of CLOFIBRATE.Fórmula:C10H11ClO3Pureza:99.47% - 99.8%Cor e Forma:Pale Yellow SolidPeso molecular:214.65LY518674
CAS:LY518674 (LY-674) decreases triglycerides and increases HDL-C and is used for the treatment of atherosclerosis.Fórmula:C23H27N3O4Pureza:98.87%Cor e Forma:SolidPeso molecular:409.48Ref: TM-T15821
1mg170,00€5mg359,00€10mg533,00€25mg847,00€50mg1.159,00€100mg1.568,00€1mL*10mM (DMSO)398,00€Fenofibric acid
CAS:Fenofibric acid (FNF acid) is the active form of fenofibrate, a synthetic phenoxy-isobutyric acid derivate with antihyperlipidemic activity.Fórmula:C17H15ClO4Pureza:99.36%Cor e Forma:White Or Almost White Crystalline PowderPeso molecular:318.75Daidzein
CAS:Daidzein (Isoflavone) is an isoflavone extract from soy, which is an inactive analog of the tyrosine kinase inhibitor genistein.Fórmula:C15H10O4Pureza:98.08%Cor e Forma:SolidPeso molecular:254.24EHP-101
CAS:EHP-101 is a PPARγ/CB2 dual agonist with anti-inflammatory properties, inhibits fat formation, and combats diet-related obesity.Fórmula:C28H35NO3Pureza:98.36%Cor e Forma:SolidPeso molecular:433.58Ref: TM-T13289
1mg107,00€5mg227,00€10mg378,00€25mg620,00€50mg868,00€100mg1.169,00€1mL*10mM (DMSO)250,00€Retinoic acid
CAS:Retinoic acid (Tretinoin) binds to and activates RARs, thereby inducing changes in gene expression that lead to inhibition of tumorigenesis.Fórmula:C20H28O2Pureza:97.21% - 99.60%Cor e Forma:Yellow-Orange PowderPeso molecular:300.44MK-0533
CAS:<p>MK-0533 is a novel PPARγ partial agonist for the prevention of vascular endothelial dysfunction (VED) and VED-related cardiovascular disease.</p>Fórmula:C28H24F3NO6Pureza:99.03%Cor e Forma:SoildPeso molecular:527.49MA-0204
CAS:MA-0204 is a highly selective and orally available peroxisome proliferator-activated receptor δ (PPARδ) modulator (EC50s: 0.4 nM, 7.9 nM and 10 nM for human,Fórmula:C25H27F3N2O4Pureza:97.8%Cor e Forma:SolidPeso molecular:476.49Ref: TM-T15945
1mg96,00€5mg178,00€10mg301,00€25mg490,00€50mg677,00€100mg900,00€200mg1.206,00€1mL*10mM (DMSO)187,00€NTP42
CAS:NTP42 is an antagonist of thromboxane A2 (TXA2) receptor(IC50 of 3.278 nM)Fórmula:C25H23F2N3O5SPureza:97.55%Cor e Forma:SolidPeso molecular:515.53Ref: TM-T12268
1mg59,00€2mg86,00€5mg133,00€10mg203,00€25mg344,00€50mg512,00€100mg735,00€1mL*10mM (DMSO)150,00€Arhalofenate
CAS:Arhalofenate (JNJ 39659100) is a selective partial agonist of peroxisome proliferator-activated receptor PPARγ. It is used for the treatment of type 2 diabetes.Fórmula:C19H17ClF3NO4Pureza:98.97%Cor e Forma:SolidPeso molecular:415.79Ref: TM-T16022
1mg62,00€5mg205,00€10mg359,00€25mg588,00€50mg825,00€100mg1.111,00€200mg1.501,00€1mL*10mM (DMSO)270,00€Candesartan
CAS:Candesartan (CV 11974) is an angiotensin II receptor blocker used widely in the therapy of hypertension and heart failure.Fórmula:C24H20N6O3Pureza:98.3% - 99.55%Cor e Forma:Colorless Solid CrystallinePeso molecular:440.47Pioglitazone hydrochloride
CAS:Pioglitazone hydrochloride (AD 4833) is the hydrochloride salt of an orally-active thiazolidinedione with antidiabetic properties and potential antineoplasticFórmula:C19H20N2O3S·HClPureza:99.64% - >99.99%Cor e Forma:White Crystals Or Crystalline PowderPeso molecular:392.90Anandamide
CAS:Anandamide ((5Z,8Z,11Z,14Z)-N-(2-Hydroxyethyl)icosa-5,8,11,14-tetraenamide), an immune modulator, acts via not only cannabinoid receptors (CB1 and CB2) but alsoFórmula:C22H37NO2Pureza:95.037% - 99.22%Cor e Forma:Light Yellow OilPeso molecular:347.53Ref: TM-T14046
1mg35,00€2mg48,00€5mg71,00€10mg124,00€25mg234,00€50mg349,00€100mg512,00€200mg713,00€1mL*10mM (DMSO)77,00€Muraglitazar
CAS:Muraglitazar (BMS-298585) is a PPAR α/γ dual agonist for the treatment of type 2 diabetes and associated dyslipidemia.Fórmula:C29H28N2O7Pureza:99.17%Cor e Forma:SolidPeso molecular:516.54Oleoylethanolamide
CAS:Oleoylethanolamide (N-Oleoylethanolamide) is a high affinity endogenous agonist of PPAR-α.Fórmula:C20H39NO2Pureza:99.98%Cor e Forma:SolidPeso molecular:325.53Ref: TM-T12296
2mg35,00€5mg52,00€10mg80,00€25mg145,00€50mg250,00€100mg376,00€200mg550,00€1mL*10mM (DMSO)58,00€Mifobate
CAS:Mifobate (SR-202) 是一种有效且特异性的 PPARγ拮抗剂，可选择性抑制噻唑烷二酮 (TZD) 诱导的 PPARγ 转录活性，IC50为140 μM，具有抗肥胖和抗糖尿病作用。Fórmula:C11H17ClO7P2Pureza:99.12%Cor e Forma:SolidPeso molecular:358.65GW7647
CAS:GW 7647 is an effective and highly selective PPARα agonist. GW 7647 can reduce the production of nitric oxide in macrophages. Cost-effective and quality-assured.Fórmula:C29H46N2O3SPureza:99.3% - 99.34%Cor e Forma:SolidPeso molecular:502.75
