Desidrogenase
As desidrogenases são enzimas envolvidas nas reações de oxidação-redução das vias metabólicas, desempenhando um papel central na produção de energia e na respiração celular. Estas enzimas são cruciais para processos como o ciclo do ácido cítrico, a glicólise e a oxidação dos ácidos graxos. Os inibidores de desidrogenases são ferramentas importantes no estudo de doenças metabólicas, câncer e estresse oxidativo. Na CymitQuimica, oferecemos uma seleção abrangente de inibidores de desidrogenases para apoiar sua pesquisa em metabolismo, biologia do câncer e bioquímica.
Foram encontrados 267 produtos de "Desidrogenase"
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Mycophenolic acid
CAS:<p>Mycophenolic acid (Mycophenolate) is an inosine monophosphate dehydrogenase(IMPDH) inhibitor with anti-proliferative activity.</p>Fórmula:C17H20O6Pureza:98.79% - 99.77%Cor e Forma:SolidPeso molecular:320.34SCD1 inhibitor-4
CAS:<p>SCD1 inhibitor-4 is stearoylCoA desaturase-1 (SCD1) inhibitor. SCD1 inhibitor-4 can be used for the research of diabetes.</p>Fórmula:C17H16F3N5OPureza:99.71%Cor e Forma:SolidPeso molecular:363.34CAY10566
CAS:<p>CAY10566 is a potent SCD1 inhibitor, orally bioavailable, with IC50s: HepG2 cells, 7.9nM; mouse, 4.5nM; human, 26nM.</p>Fórmula:C18H17ClFN5O2Pureza:99.5% - 99.54%Cor e Forma:SolidPeso molecular:389.81CVT-10216
CAS:<p>CVT-10216 inhibits ALDH2 (IC50: 29 nM) and ALDH-1 (IC50: 1.3 μM), reducing alcohol intake and anxiety in rats.</p>Fórmula:C24H19NO7SPureza:98.76%Cor e Forma:SolidPeso molecular:465.48KPLH1130
CAS:<p>KPLH1130, a PDK inhibitor, boosts glucose tolerance and reduces inflammation in high-fat diet mice.</p>Fórmula:C15H13N3O3Pureza:99.07%Cor e Forma:SolidPeso molecular:283.28MF-438
CAS:<p>MF-438 is an effective and orally bioavailable stearoyl-CoA desaturase 1 (SCD1) inhibitor (EC50: 2.3 nM for rSCD1).</p>Fórmula:C19H18F3N5OSPureza:98.98% - 99.50%Cor e Forma:SolidPeso molecular:421.44LY 345899
CAS:<p>LY 345899 is a Folate analog and is a methylenetetrahydrofolate dehydrogenase and MTHFD2 inhibitor (IC50: 96 nM and 663 nM, respectively and a Ki: 18 nM for</p>Fórmula:C20H21N7O7Pureza:99.7%Cor e Forma:SolidPeso molecular:471.42BAY-2402234
CAS:<p>BAY-2402234: a selective DHODH inhibitor targeting myeloid cancers with low-nanomolar potency.</p>Fórmula:C21H18ClF5N4O4Pureza:98.9%Cor e Forma:SolidPeso molecular:520.84ML390
CAS:<p>ML390 exerts its potent differentiation effect on multiple leukemia models.</p>Fórmula:C21H21F3N2O3Pureza:99.76%Cor e Forma:SolidPeso molecular:406.4NCT-502
CAS:<p>NCT-502 (N-(4,6-dimethylpyridin-2-yl)-4-[5-(trifluoromethyl)pyridin-2-yl]piperazine-1-carbothioamide) is a human phosphoglycerate dehydrogenase inhibitor,</p>Fórmula:C18H20F3N5SPureza:99.60%Cor e Forma:SolidPeso molecular:395.45PTC299
CAS:<p>PTC299 ((4-chlorophenyl) (1S)-6-chloro-1-(4-methoxyphenyl)-1,3,4,9-tetrahydropyrido[3,4-b]indole-2-carboxylate) is an orally active inhibitor of VEGFA mRNA</p>Fórmula:C25H20Cl2N2O3Pureza:99.72%Cor e Forma:SolidPeso molecular:467.34LDH-IN-1
CAS:<p>LDH-IN-1 is a pyrazole-based human lactate dehydrogenase (LDH) inhibitor(IC50s of 32 and 27 nM for LDHA and LDHB, respectively).</p>Fórmula:C30H26N4O4S2Pureza:99.6%Cor e Forma:SolidPeso molecular:570.68XEN723
CAS:<p>XEN723 is a potent thiazolylimidazolidinone Stearoyl-CoA Desaturase (SCD1) inhibitor(IC50s of 45 and 524 nM in mouse and HepG2 cell, respectively).</p>Fórmula:C21H20FN5O2SPureza:99.5%Cor e Forma:SolidPeso molecular:425.48CBR-5884
CAS:<p>CBR-5884: active PHGDH inhibitor, IC50=33μM, disrupts serine synthesis, selectively targets high-serine cancers.</p>Fórmula:C14H12N2O4S2Pureza:99.97%Cor e Forma:SolidPeso molecular:336.39DHODH-IN-11
CAS:<p>DHODH-IN-11 is a leflunomide derivative and weak dihydroorotate dehydrogenase (DHODH) inhibitor with a pKa of 5.03.</p>Fórmula:C15H11N3O2Pureza:98.14%Cor e Forma:SolidPeso molecular:265.27Adrenosterone
CAS:<p>Adrenosterone (11-ketoandrostenedione) is a steroid hormone isolated from the adrenal cortex.</p>Fórmula:C19H24O3Pureza:98.13% - 98.29%Cor e Forma:SolidPeso molecular:300.39Trilostane
CAS:<p>Trilostane (Win 24540) is a synthetic derivative of androstane with adrenocortical suppressive properties.</p>Fórmula:C20H27NO3Pureza:99.46% - >99.99%Cor e Forma:Tan CrystalsPeso molecular:329.43IDH-305
CAS:<p>IDH-305: Oral, mutation-specific IDH1 inhibitor, 200x selective for R132 mutants; IC50: 27/28/6.14 nM for R132H/C/WT.</p>Fórmula:C23H22F4N6O2Pureza:99.68%Cor e Forma:SolidPeso molecular:490.45RS 61443
CAS:<p>RS 61443 (Mycophenolate mofetil) is an immunosuppressant, a non-competitive, selective and reversible inhibitor of inosine monophosphate dehydrogenase (IMPDH)</p>Fórmula:C23H31NO7Pureza:99.37% - 99.91%Cor e Forma:SolidPeso molecular:433.5Mutant IDH1 inhibitor
CAS:<p>Mutant IDH1 inhibitor is an effective inhibitor of mutant IDH1 R132H (IC50: < 72 nM).</p>Fórmula:C25H34N6O3Pureza:98.3%Cor e Forma:SolidPeso molecular:466.58
