Desidrogenase
As desidrogenases são enzimas envolvidas nas reações de oxidação-redução das vias metabólicas, desempenhando um papel central na produção de energia e na respiração celular. Estas enzimas são cruciais para processos como o ciclo do ácido cítrico, a glicólise e a oxidação dos ácidos graxos. Os inibidores de desidrogenases são ferramentas importantes no estudo de doenças metabólicas, câncer e estresse oxidativo. Na CymitQuimica, oferecemos uma seleção abrangente de inibidores de desidrogenases para apoiar sua pesquisa em metabolismo, biologia do câncer e bioquímica.
Foram encontrados 302 produtos de "Desidrogenase"
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LDH-IN-1
CAS:LDH-IN-1 is a pyrazole-based human lactate dehydrogenase (LDH) inhibitor(IC50s of 32 and 27 nM for LDHA and LDHB, respectively).Fórmula:C30H26N4O4S2Pureza:99.6%Cor e Forma:SolidPeso molecular:570.68Ref: TM-T11829
1mg188,00€5mg393,00€10mg588,00€25mg938,00€50mg1.359,00€100mg1.786,00€200mg2.442,00€1mL*10mM (DMSO)494,00€SCD1 inhibitor-4
CAS:SCD1 inhibitor-4 is stearoylCoA desaturase-1 (SCD1) inhibitor. SCD1 inhibitor-4 can be used for the research of diabetes.Fórmula:C17H16F3N5OPureza:99.71%Cor e Forma:SolidPeso molecular:363.34Ref: TM-T10525
2mg43,00€5mg60,00€10mg99,00€25mg192,00€50mg309,00€100mg444,00€200mg617,00€1mL*10mM (DMSO)71,00€RS 61443
CAS:RS 61443 (Mycophenolate mofetil) is an immunosuppressant, a non-competitive, selective and reversible inhibitor of inosine monophosphate dehydrogenase (IMPDH)Fórmula:C23H31NO7Pureza:99.37% - 99.96%Cor e Forma:SolidPeso molecular:433.5Mycophenolic acid
CAS:Mycophenolic acid (Mycophenolate) is an inosine monophosphate dehydrogenase(IMPDH) inhibitor with anti-proliferative activity.Fórmula:C17H20O6Pureza:98.79% - 99.77%Cor e Forma:SolidPeso molecular:320.34XEN723
CAS:XEN723 is a potent thiazolylimidazolidinone Stearoyl-CoA Desaturase (SCD1) inhibitor(IC50s of 45 and 524 nM in mouse and HepG2 cell, respectively).Fórmula:C21H20FN5O2SPureza:99.5%Cor e Forma:SolidPeso molecular:425.48Ref: TM-T13356
1mg52,00€5mg110,00€10mg170,00€25mg289,00€50mg414,00€100mg583,00€200mg785,00€1mL*10mM (DMSO)132,00€MF-438
CAS:MF-438 is an effective and orally bioavailable stearoyl-CoA desaturase 1 (SCD1) inhibitor (EC50: 2.3 nM for rSCD1).Fórmula:C19H18F3N5OSPureza:98.98% - 99.50%Cor e Forma:SolidPeso molecular:421.44Ref: TM-T16068
1mg97,00€2mg144,00€5mg215,00€10mg328,00€25mg557,00€50mg797,00€100mg1.103,00€500mg2.205,00€1mL*10mM (DMSO)235,00€BAY-2402234
CAS:BAY-2402234: a selective DHODH inhibitor targeting myeloid cancers with low-nanomolar potency.Fórmula:C21H18ClF5N4O4Pureza:98.9%Cor e Forma:SolidPeso molecular:520.84Ref: TM-T14501
1mg170,00€2mg234,00€5mg349,00€10mg537,00€25mg858,00€50mg1.161,00€100mg1.558,00€1mL*10mM (DMSO)401,00€CAY10566
CAS:CAY10566 is a potent SCD1 inhibitor, orally bioavailable, with IC50s: HepG2 cells, 7.9nM; mouse, 4.5nM; human, 26nM.Fórmula:C18H17ClFN5O2Pureza:99.5% - 99.54%Cor e Forma:SolidPeso molecular:389.81Ref: TM-T14878
1mg50,00€5mg138,00€10mg205,00€25mg373,00€50mg533,00€100mg748,00€200mg1.008,00€1mL*10mM (DMSO)118,00€CVT-10216
CAS:CVT-10216 inhibits ALDH2 (IC50: 29 nM) and ALDH-1 (IC50: 1.3 μM), reducing alcohol intake and anxiety in rats.Fórmula:C24H19NO7SPureza:98.76%Cor e Forma:SolidPeso molecular:465.48NCT-502
CAS:NCT-502 (N-(4,6-dimethylpyridin-2-yl)-4-[5-(trifluoromethyl)pyridin-2-yl]piperazine-1-carbothioamide) is a human phosphoglycerate dehydrogenase inhibitor,Fórmula:C18H20F3N5SPureza:99.60%Cor e Forma:SolidPeso molecular:395.45Ref: TM-T16277
2mg39,00€5mg57,00€10mg87,00€25mg159,00€50mg240,00€100mg415,00€500mg933,00€1mL*10mM (DMSO)63,00€LY 345899
CAS:LY 345899 is a Folate analog and is a methylenetetrahydrofolate dehydrogenase and MTHFD2 inhibitor (IC50: 96 nM and 663 nM, respectively and a Ki: 18 nM for
Fórmula:C20H21N7O7Pureza:99.7%Cor e Forma:SolidPeso molecular:471.42KPLH1130
CAS:KPLH1130, a PDK inhibitor, boosts glucose tolerance and reduces inflammation in high-fat diet mice.
Fórmula:C15H13N3O3Pureza:99.07%Cor e Forma:SolidPeso molecular:283.28PTC299
CAS:PTC299 ((4-chlorophenyl) (1S)-6-chloro-1-(4-methoxyphenyl)-1,3,4,9-tetrahydropyrido[3,4-b]indole-2-carboxylate) is an orally active inhibitor of VEGFA mRNAFórmula:C25H20Cl2N2O3Pureza:99.72%Cor e Forma:SolidPeso molecular:467.34Ref: TM-T12574
1mg117,00€5mg243,00€10mg369,00€25mg622,00€50mg885,00€100mg1.206,00€1mL*10mM (DMSO)250,00€CBR-5884
CAS:CBR-5884: active PHGDH inhibitor, IC50=33μM, disrupts serine synthesis, selectively targets high-serine cancers.Fórmula:C14H12N2O4S2Pureza:99.97%Cor e Forma:SolidPeso molecular:336.39DHODH-IN-11
CAS:DHODH-IN-11 is a leflunomide derivative and weak dihydroorotate dehydrogenase (DHODH) inhibitor with a pKa of 5.03.Fórmula:C15H11N3O2Pureza:98.14%Cor e Forma:SolidPeso molecular:265.27Adrenosterone
CAS:Adrenosterone (11-ketoandrostenedione) is a steroid hormone isolated from the adrenal cortex.Fórmula:C19H24O3Pureza:98.13% - 98.29%Cor e Forma:SolidPeso molecular:300.39Trilostane
CAS:Trilostane (Win 24540) is a synthetic derivative of androstane with adrenocortical suppressive properties.Fórmula:C20H27NO3Pureza:99.46% - >99.99%Cor e Forma:Tan CrystalsPeso molecular:329.43IDH-305
CAS:IDH-305: Oral, mutation-specific IDH1 inhibitor, 200x selective for R132 mutants; IC50: 27/28/6.14 nM for R132H/C/WT.Fórmula:C23H22F4N6O2Pureza:99.68%Cor e Forma:SolidPeso molecular:490.45ML390
CAS:ML390 exerts its potent differentiation effect on multiple leukemia models.Fórmula:C21H21F3N2O3Pureza:99.76%Cor e Forma:SolidPeso molecular:406.4Mutant IDH1 inhibitor
CAS:Mutant IDH1 inhibitor is an effective inhibitor of mutant IDH1 R132H (IC50: < 72 nM).Fórmula:C25H34N6O3Pureza:98.3%Cor e Forma:SolidPeso molecular:466.58Ref: TM-T16161
1mg39,00€5mg86,00€10mg128,00€25mg210,00€50mg306,00€100mg429,00€200mg597,00€1mL*10mM (DMSO)89,00€
