Desidrogenase
As desidrogenases são enzimas envolvidas nas reações de oxidação-redução das vias metabólicas, desempenhando um papel central na produção de energia e na respiração celular. Estas enzimas são cruciais para processos como o ciclo do ácido cítrico, a glicólise e a oxidação dos ácidos graxos. Os inibidores de desidrogenases são ferramentas importantes no estudo de doenças metabólicas, câncer e estresse oxidativo. Na CymitQuimica, oferecemos uma seleção abrangente de inibidores de desidrogenases para apoiar sua pesquisa em metabolismo, biologia do câncer e bioquímica.
Foram encontrados 267 produtos de "Desidrogenase"
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LDH-IN-1
CAS:<p>LDH-IN-1 is a pyrazole-based human lactate dehydrogenase (LDH) inhibitor(IC50s of 32 and 27 nM for LDHA and LDHB, respectively).</p>Fórmula:C30H26N4O4S2Pureza:99.6%Cor e Forma:SolidPeso molecular:570.68Mutant IDH1 inhibitor
CAS:<p>Mutant IDH1 inhibitor is an effective inhibitor of mutant IDH1 R132H (IC50: < 72 nM).</p>Fórmula:C25H34N6O3Pureza:98.3%Cor e Forma:SolidPeso molecular:466.58DHODH-IN-11
CAS:<p>DHODH-IN-11 is a leflunomide derivative and weak dihydroorotate dehydrogenase (DHODH) inhibitor with a pKa of 5.03.</p>Fórmula:C15H11N3O2Pureza:98.14%Cor e Forma:SolidPeso molecular:265.27CVT-10216
CAS:<p>CVT-10216 inhibits ALDH2 (IC50: 29 nM) and ALDH-1 (IC50: 1.3 μM), reducing alcohol intake and anxiety in rats.</p>Fórmula:C24H19NO7SPureza:98.76%Cor e Forma:SolidPeso molecular:465.48BAY-2402234
CAS:<p>BAY-2402234: a selective DHODH inhibitor targeting myeloid cancers with low-nanomolar potency.</p>Fórmula:C21H18ClF5N4O4Pureza:98.9%Cor e Forma:SolidPeso molecular:520.84Olutasidenib
CAS:<p>Olutasidenib (FT-2102), an IDH1 inhibitor (IC50: 21.2/114 nM), is studied for treating AML/MDS and can cross the blood-brain barrier.</p>Fórmula:C18H15ClN4O2Pureza:98.57%Cor e Forma:SolidPeso molecular:354.79SCD1 inhibitor-4
CAS:<p>SCD1 inhibitor-4 is stearoylCoA desaturase-1 (SCD1) inhibitor. SCD1 inhibitor-4 can be used for the research of diabetes.</p>Fórmula:C17H16F3N5OPureza:99.71%Cor e Forma:SolidPeso molecular:363.344-Diethylaminobenzaldehyde
CAS:<p>4-Diethylaminobenzaldehyde: reversible ALDH1 inhibitor (Ki: 4 nM), potent anti-androgen (IC50: 1.71μM).</p>Fórmula:C11H15NOPureza:99.6%Cor e Forma:Brown-Black CrystalsPeso molecular:177.24ML390
CAS:<p>ML390 exerts its potent differentiation effect on multiple leukemia models.</p>Fórmula:C21H21F3N2O3Pureza:99.76%Cor e Forma:SolidPeso molecular:406.4CAY10566
CAS:<p>CAY10566 is a potent SCD1 inhibitor, orally bioavailable, with IC50s: HepG2 cells, 7.9nM; mouse, 4.5nM; human, 26nM.</p>Fórmula:C18H17ClFN5O2Pureza:99.5% - 99.54%Cor e Forma:SolidPeso molecular:389.81GSK2837808A
CAS:<p>GSK2837808A is a potent and selective inhibitor of lactate dehydrogenase A (LDHA) (IC50s: 1.9 and 14 nM for LDHA and LDHB, respectively).</p>Fórmula:C31H25F2N5O7SPureza:99.78% - 99.78%Cor e Forma:SolidPeso molecular:649.62MF-438
CAS:<p>MF-438 is an effective and orally bioavailable stearoyl-CoA desaturase 1 (SCD1) inhibitor (EC50: 2.3 nM for rSCD1).</p>Fórmula:C19H18F3N5OSPureza:98.98% - 99.50%Cor e Forma:SolidPeso molecular:421.44Mycophenolic acid
CAS:<p>Mycophenolic acid (Mycophenolate) is an inosine monophosphate dehydrogenase(IMPDH) inhibitor with anti-proliferative activity.</p>Fórmula:C17H20O6Pureza:98.79% - 99.77%Cor e Forma:SolidPeso molecular:320.34NCT-502
CAS:<p>NCT-502 (N-(4,6-dimethylpyridin-2-yl)-4-[5-(trifluoromethyl)pyridin-2-yl]piperazine-1-carbothioamide) is a human phosphoglycerate dehydrogenase inhibitor,</p>Fórmula:C18H20F3N5SPureza:99.60%Cor e Forma:SolidPeso molecular:395.45Trilostane
CAS:<p>Trilostane (Win 24540) is a synthetic derivative of androstane with adrenocortical suppressive properties.</p>Fórmula:C20H27NO3Pureza:99.46% - >99.99%Cor e Forma:Tan CrystalsPeso molecular:329.43CBR-5884
CAS:<p>CBR-5884: active PHGDH inhibitor, IC50=33μM, disrupts serine synthesis, selectively targets high-serine cancers.</p>Fórmula:C14H12N2O4S2Pureza:99.97%Cor e Forma:SolidPeso molecular:336.39RS 61443
CAS:<p>RS 61443 (Mycophenolate mofetil) is an immunosuppressant, a non-competitive, selective and reversible inhibitor of inosine monophosphate dehydrogenase (IMPDH)</p>Fórmula:C23H31NO7Pureza:99.37% - 99.91%Cor e Forma:SolidPeso molecular:433.5Adrenosterone
CAS:<p>Adrenosterone (11-ketoandrostenedione) is a steroid hormone isolated from the adrenal cortex.</p>Fórmula:C19H24O3Pureza:98.13% - 98.29%Cor e Forma:SolidPeso molecular:300.39KPLH1130
CAS:<p>KPLH1130, a PDK inhibitor, boosts glucose tolerance and reduces inflammation in high-fat diet mice.</p>Fórmula:C15H13N3O3Pureza:99.07%Cor e Forma:SolidPeso molecular:283.28LY 345899
CAS:<p>LY 345899 is a Folate analog and is a methylenetetrahydrofolate dehydrogenase and MTHFD2 inhibitor (IC50: 96 nM and 663 nM, respectively and a Ki: 18 nM for</p>Fórmula:C20H21N7O7Pureza:99.7%Cor e Forma:SolidPeso molecular:471.42PTC299
CAS:<p>PTC299 ((4-chlorophenyl) (1S)-6-chloro-1-(4-methoxyphenyl)-1,3,4,9-tetrahydropyrido[3,4-b]indole-2-carboxylate) is an orally active inhibitor of VEGFA mRNA</p>Fórmula:C25H20Cl2N2O3Pureza:99.72%Cor e Forma:SolidPeso molecular:467.34IDH-305
CAS:<p>IDH-305: Oral, mutation-specific IDH1 inhibitor, 200x selective for R132 mutants; IC50: 27/28/6.14 nM for R132H/C/WT.</p>Fórmula:C23H22F4N6O2Pureza:99.68%Cor e Forma:SolidPeso molecular:490.45XEN723
CAS:<p>XEN723 is a potent thiazolylimidazolidinone Stearoyl-CoA Desaturase (SCD1) inhibitor(IC50s of 45 and 524 nM in mouse and HepG2 cell, respectively).</p>Fórmula:C21H20FN5O2SPureza:99.5%Cor e Forma:SolidPeso molecular:425.48Antiproliferative agent-13
CAS:<p>Antiproliferative agent-13 is a compound with antiproliferative activity.</p>Fórmula:C20H18N2O6Pureza:99.723%Cor e Forma:SolidPeso molecular:382.37DSM705
CAS:<p>DSM705: Pyrrole-based, potent nanomolar Plasmodium DHODH inhibitor with strong antimalarial efficacy; spares mammalian DHODH.</p>Fórmula:C19H19F3N6OCor e Forma:SolidPeso molecular:404.397Diethanolamine hydrochloride
CAS:<p>Diethanolamine hydrochloride is HSD17B4 (hydroxysteroid 17-beta dehydrogenase 4) and pregnane X receptor (PXR), p53 Estrogen receptor.</p>Fórmula:C4H12ClNO2Pureza:99.69%Cor e Forma:SolidPeso molecular:141.6DHODH-IN-16
CAS:<p>DHODH-IN-16 is an effective inhibitor of dihydroorotate dehydrogenase (DHODH, IC50 = 0.396 nM for human).</p>Fórmula:C24H25FN4O3Pureza:99.64%Cor e Forma:SolidPeso molecular:436.48WAY-311610
CAS:<p>WAY-311610 is an HSD11B1 inhibitor targeting 11β-HSD1 enzyme with 0.34 μM IC; used for neuropathic and inflammatory pain research.</p>Fórmula:C16H13F3N4O2Pureza:98.01%Cor e Forma:SolidPeso molecular:350.3hDHODH-IN-8
CAS:<p>hDHODH-IN-8: potent hDHODH inhibitor, IC50 = 16 nM, antiproliferative, soluble, may research lymphoma.</p>Fórmula:C21H15F6N3O4Pureza:98%Cor e Forma:SoildPeso molecular:487.3511β-HSD1 inibitor 19
CAS:<p>3-chloro-4-sulfonyl-Benzonitrile inhibits hHSD1/mHSD1, IC50: 16nM/10nM.</p>Fórmula:C19H16ClF4N3O2SPureza:99.58%Cor e Forma:SoildPeso molecular:461.86hDHODH-IN-12
<p>hDHODH-IN-12 is a potent inhibitor of dihydroorotate dehydrogenase (DHODH), exhibiting an inhibitory concentration (IC50) of 0.421 μM.</p>Fórmula:C22H15F3N4O3Pureza:98%Cor e Forma:SolidPeso molecular:440.37LDHA-IN-8
CAS:<p>LDHA-IN-8, an inhibitor, inhibits the proliferation of pancreatic and lung cancer cells, decreasing the intracellular lactate content and increasing ROS levels.</p>Fórmula:C15H14N4O2Pureza:99.73%Cor e Forma:SolidPeso molecular:282.3IGUANA-1
CAS:<p>IGUANA-1 is a highly efficient and selective ALDH1B1 inhibitor that inhibits the growth of colorectal cancer cells and colorectal cancer cell-derived organoids.</p>Fórmula:C27H26ClN3O4Pureza:99.08%Cor e Forma:SolidPeso molecular:491.97DHODH-IN-23
CAS:<p>DHODH-IN-23 is a DHODH inhibitor with oral activity. DHODH-IN-23 is often used in cancer research.</p>Fórmula:C24H21ClFNO4Pureza:99.7%Cor e Forma:SolidPeso molecular:441.88Nedosiran sodium
CAS:<p>Nedosiran sodium, a GalNAc-dsRNA conjugate, is engineered to suppress the synthesis of the hepatic lactate dehydrogenase (LDH) enzyme.</p>Cor e Forma:SolidMTHFD2-IN-3
<p>MTHFD2-IN-3 (compound 10), a potent inhibitor of methylenetetrahydrofolate dehydrogenase (MTHFD2), demonstrates significant efficacy in obstructing the activity</p>Fórmula:C22H19NO7SCor e Forma:SolidPeso molecular:441.452,3-Dihydroxybenzaldehyde
CAS:<p>2,3-Dihydroxybenzaldehyde exhibits activity against NADH dehydrogenase (Km = 35 µM) and can be used in biochemical experiments and drug synthesis.</p>Fórmula:C7H6O3Cor e Forma:SolidPeso molecular:138.12Octanoyl Coenzyme A (sodium salt)
<p>Octanoyl Coenzyme A (sodium salt) inhibits citrate synthase and glutamate dehydrogenase with an IC50 of 0.4–1.6 mM.</p>Fórmula:C29H49N7NaO17P3SCor e Forma:SolidPeso molecular:915.71PDK-IN-2
<p>PDK-IN-2 (Compound 1F), with an IC50 of 68 nM, is a potent PDK inhibitor that downregulates the expression of PDK1 and PDK4 in cells.</p>Fórmula:C17H23AsCl2N2O2S2Cor e Forma:SolidPeso molecular:497.3311β-HSD1 inibitor 17
CAS:<p>11β-HSD1 inibitor 17 is an inhibitor of 11β-hydroxysteroid dehydrogenase (11β-HSD1).</p>Fórmula:C22H20F3N3O2SPureza:99.26% - 99.72%Cor e Forma:SoildPeso molecular:447.4711β-HSD1-IN-11
CAS:<p>11β-HSd1-in-11 is a potent and competitive inhibitor of 11-β-hydroxysteroid dehydrogenase 1 (11β-HSD1) IN rats and humans with IC50 values of 0.34 μM and 0.13</p>Fórmula:C15H11F3O3SPureza:99.61%Cor e Forma:SoildPeso molecular:328.31MTHFD2-IN-4 sodium
<p>MTHFD2-IN-4 sodium, a potent inhibitor of MTHFD2 and a tricyclic coumarin derivative, is applicable in cancer research [1].</p>Fórmula:C26H21F6N2NaO5Cor e Forma:SolidPeso molecular:578.44MTHFD2-IN-4
<p>MTHFD2-IN-4, a tricyclic coumarin derivative, serves as a potent inhibitor of MTHFD2 and has applications in cancer research [1].</p>Fórmula:C26H21F6N2O5Cor e Forma:SolidPeso molecular:555.45IGUANA-1 free base
CAS:<p>IGUANA-1: selective ALDH1 B1 inhibitor, IC50=30 nM, hinders SW480 cell growth with IC50=2.46/0.39 μM in adherent/spheroid forms, for cancer research.</p>Fórmula:C26H24ClN3O2Cor e Forma:SolidPeso molecular:445.94PDK-IN-1
CAS:<p>PDK-IN-1, a PDK inhibitor, IC50: 0.03μM (PDK1), 0.1μM (HSP90), reduces tumor mass.</p>Fórmula:C20H16BrN7OCor e Forma:SolidPeso molecular:450.29MTHFD2-IN-2
<p>MTHFD2-IN-2 (compound 13) serves as a potent inhibitor of methylenetetrahydrofolate dehydrogenase (MTHFD2) [1].</p>Fórmula:C22H18N4O5Cor e Forma:SolidPeso molecular:418.4Necroptosis-IN-3
CAS:<p>Necroptosis-IN-3 (Cyclohexanecarboxamide, N-(2-thienylmethyl)-) (Compound 69) is a Necroptosis inhibitor that inhibits TNF-α induced necroptosis.</p>Fórmula:C12H17NOSPureza:99.85%Cor e Forma:SoildPeso molecular:223.33CM121
CAS:<p>CM121, a reversible ALDH1A2 inhibitor, targets active site with IC50=0.54μM, Kd=1.1μM, using hydrophobic interactions.</p>Fórmula:C24H17FN4O3SCor e Forma:SolidPeso molecular:460.4818β-Glycyrrhetyl-3-O-sulfate
CAS:<p>18β-Glycyrrhetyl-3-O-sulfate (Glycyrrhetic acid 3-O-(hydrogen sulfate)), a major metabolite of Glycyrrhetinic acid (GA), serves as a potent inhibitor of type 2</p>Fórmula:C30H46O7SCor e Forma:SolidPeso molecular:550.75MTHFD2-IN-1
<p>MTHFD2-IN-1 (compound 12) is a potent inhibitor of methylenetetrahydrofolate dehydrogenase (MTHFD2) [1].</p>Fórmula:C24H21NO6Cor e Forma:SolidPeso molecular:419.43DHODH-IN-18
CAS:<p>DHODH-IN-18 is a human DHODH inhibitor ( IC 50 = 0.2 nM).</p>Fórmula:C21H16ClF5N6O4Cor e Forma:SolidPeso molecular:546.84SKI2852
CAS:<p>SKI2852 is an 11β-HSD1 inhibitor that improves metabolic syndrome in diabetic mouse models.</p>Fórmula:C27H34FN5O4SPureza:99.89%Cor e Forma:SolidPeso molecular:543.6517β-HSD10-IN-1
CAS:<p>17β-HSD10-IN-1 is a 17β-hydroxysteroid dehydrogenase type 10 inhibitor with blood-brain permeability and potency for the study of Alzheimer's disease.</p>Fórmula:C16H13ClN4O3SPureza:98.47%Cor e Forma:SoildPeso molecular:376.82LDHA-IN-3
CAS:<p>LDHA-IN-3 is a potent selenobenzene-based LDHA inhibitor with a 145.2 nM IC50, useful in cancer research.</p>Fórmula:C13H9F3SePureza:99.71%Cor e Forma:SolidPeso molecular:301.17TC HSD 21
CAS:<p>TC HSD 21 is a potent and highly selective inhibitor of 17β-hydroxysteroid dehydrogenase type 3 (IC50 = 14 nM).</p>Fórmula:C17H12BrNO3S2Pureza:98.5%Cor e Forma:SolidPeso molecular:422.32Ascochlorin A
CAS:<p>Ascochlorin A, a compound with a dissociation constant (K D) of 3.29 μM, serves as a novel and potent human dihydroorotate dehydrogenase (hDHODH) inhibitor</p>Fórmula:C23H31ClO4Cor e Forma:SolidPeso molecular:406.95SW209049
CAS:<p>SW209049 is a stearoyl-CoA 9-desaturase inhibitor. SW209049 exhivits potent activity against H2122 cell with IC50 of 0.13uM.</p>Fórmula:C25H18N2O4SPureza:99.72%Cor e Forma:SolidPeso molecular:442.49KOTX1
CAS:<p>KOTX1 is an orally active and selective inhibitor of ALDH1A3. In a diabetic mouse model, KOTX1 improves glucose tolerance, insulin secretion, and blood glucose levels.</p>Fórmula:C17H16FN3O2Cor e Forma:SolidPeso molecular:313.33hDHODH-IN-13
CAS:<p>hDHODH-IN-13 (compound w2), an inhibitor of human dihydroorotate dehydrogenase (hDHODH), exhibits an IC50 of 173.4 nM and has potential research applications in</p>Cor e Forma:SoildhDHODH-IN-16
<p>hDHODH-IN-16 (Compound 3t) is an inhibitor of human dihydroorotate dehydrogenase (hDHODH) with an IC50 of 0.11 μM. It demonstrates very low cytotoxicity towards healthy HaCaT cells, with an IC50 value exceeding 200 μM.</p>Fórmula:C18H20N2O2Cor e Forma:SolidPeso molecular:296.36SCD1 inhibitor-3
CAS:<p>SCD1 inhibitor-3 (ML-270) is a highly effective and orally available compound that inhibits SCD1 with remarkable safety.</p>Fórmula:C19H16FN7O2Pureza:99.5%Cor e Forma:SolidPeso molecular:393.37BVT-2733 hydrochloride
CAS:<p>BVT-2733 hydrochloride is a potent, selective, and orally active non-steroidal 11β-HSD1 inhibitor. It exhibits stronger inhibition on mouse 11β-HSD1 enzyme (IC50=96 nM) compared to the human 11β-HSD1 enzyme (IC50=3341 nM). BVT-2733 hydrochloride shows potential for research in arthritis and obesity-related diseases.</p>Fórmula:C17H22Cl2N4O3S2Cor e Forma:SolidPeso molecular:465.42D-Lactate dehydrogenase
CAS:<p>D-LDH is an oxidoreductase turning D-lactate into pyruvate, using NAD+/NADP+; prevalent in bacteria and fungi, key for biochemical research.</p>Cor e Forma:SolidOsmanthuside H
CAS:<p>Osmanthuside H is a useful organic compound for research related to life sciences. The catalog number is T125796 and the CAS number is 149155-70-4.</p>Fórmula:C19H28O11Cor e Forma:SolidPeso molecular:432.422MCI-INI-3
CAS:<p>MCI-INI-3 is a selective competitive inhibitor of human ALDH1A3, with a Ki value of 0.55 μM for ALDH1A3 and 78.2 μM for ALDH1A1. It inhibits retinoic acid biosynthesis and can reduce the viability of glioblastoma cells GSC-83 and GSC-326.</p>Fórmula:C21H15N3O4Cor e Forma:SolidPeso molecular:373.36(Rac)-BMS-816336
<p>(Rac)-BMS-816336 is a racemic 11β-HSD1 inhibitor; IC50: 10 nM (human), 68 nM (mouse), metabolically stable.</p>Fórmula:C21H27NO3Pureza:98%Cor e Forma:SolidPeso molecular:341.44DSM1465
<p>DSM1465 (Compound 82) is a potent and selective inhibitor of P. falciparum dihydroorotate dehydrogenase (PfDHODH) with an IC50 value of 15 nM. It inhibits P. falciparum 3D7 (Pf3D7) parasites with an EC50 value of 1.4 nM and demonstrates significant in vivo efficacy in humanized P. falciparum mouse models.</p>Fórmula:C17H12ClF6N5O2Cor e Forma:SolidPeso molecular:467.753BMS-770767
CAS:<p>BMS-770767 is a novel 11-betahydroxysteroid dehydrogenase type I (11ß-HSD1) inhibitor.</p>Fórmula:C19H18ClN3O2Cor e Forma:SolidPeso molecular:355.82Crelosidenib
CAS:<p>Crelosidenib is a potent and selective mutant IDH inhibitor for IDH1 R132H, IDH1 R132C, IDH2 R140Q, and IDH2 R172K mutases.</p>Fórmula:C28H36N6O3Pureza:98.54%Cor e Forma:SolidPeso molecular:504.62ALDH1A2-IN-1
CAS:<p>ALDH1A2-IN-1 is a reversible active-site-directed ALDH1A2 inhibitor preventing spermatogenesis, useful in male contraceptive research.</p>Fórmula:C21H26N4O4SPureza:99.51%Cor e Forma:SolidPeso molecular:430.52ALDH3A1-IN-1
CAS:<p>ALDH3A1-IN-1 (Compound 18) is a potent inhibitor of ALDH3A1 with IC50 of 1.61 μM, outperforms DEAB in prostate cancer cells.</p>Fórmula:C13H18N2O3Pureza:99.86%Cor e Forma:SolidPeso molecular:250.29Aldehyde dehydrogenase (NAD(P))
CAS:<p>ALDH catalyzes oxidation of aldehydes to acids, reducing NAD(P) to NAD(P)H, helping alleviate aldehyde stress.</p>Cor e Forma:SolidABT-384
CAS:<p>ABT-384 is a high-affinity, selective 11β-HSD1 inhibitor capable of suppressing hepatic and central nervous system HSD-1 activity for depressive disorder.</p>Fórmula:C25H34F3N5O2Pureza:99.863%Cor e Forma:SolidPeso molecular:493.58ALDH1A3-IN-1
CAS:<p>ALDH1A3-IN-1 (Compound 14) is a potent inhibitor of ALDH1A3 which can be used in prostate cancer research (IC50 = 0.63 μM; Ki = 0.46 μM) [1].</p>Fórmula:C13H18BrNOCor e Forma:SolidPeso molecular:284.192-Bromoacetamide
CAS:<p>2-Bromoacetamide (α-Bromoacetamide) is a class of disinfection by-products that exhibit developmental toxicity in animals.</p>Fórmula:C2H4BrNOPureza:99.83%Cor e Forma:SolidPeso molecular:137.96DSM265
CAS:<p>DSM265 (PfSPZ) is a dihydroorotic acid dehydrogenase inhibitor with antimalarial activity.DSM265 can be used for the treatment of malaria infections.</p>Fórmula:C14H12F7N5SPureza:99.79%Cor e Forma:SolidPeso molecular:415.334-Isopropoxybenzaldehyde
CAS:<p>ALDH1A3-IN-3 inhibits ALDH1A3 (IC50: 0.26 μM), acts on ALDH3A1, and is used in prostate cancer research.</p>Fórmula:C10H12O2Pureza:99.00%Cor e Forma:SolidPeso molecular:164.2DSM502
CAS:<p>DSM502 DSM502 is a dihydroorotic acid dehydrogenase (DHODH) inhibitor with antimalarial activity that inhibits Plasmodium DHODH and can be used as a lead for antimalarial compounds.</p>Fórmula:C16H16F3N3OPureza:99.52%Cor e Forma:SolidPeso molecular:323.31Ketogestin
CAS:<p>Ketogestin is a progestational steroid and an inhibitor of enzyme 11β-hydroxysteroid dehydrogenase, and a weak negative modulator of GABAA receptors.</p>Fórmula:C21H28O3Pureza:99.19%Cor e Forma:SolidPeso molecular:328.45PKUMDL-WQ-2201
CAS:<p>PKUMDL-WQ-2201 is a selective allosteric inhibitor of phosphoglycerate dehydrogenase (PHGDH) with Anti-tumor Activity, it binds to site II.</p>Fórmula:C15H14ClN3O3SCor e Forma:SolidPeso molecular:351.81Perfluorooctanoic acid
CAS:<p>Perfluorooctanoic acid (PFOA) (PFOA) is a persistent and widespread industry-made chemical.</p>Fórmula:C8HF15O2Pureza:99.70%Cor e Forma:White To Off-White Powder OthersolidPeso molecular:414.07Nitrofurazone
CAS:<p>Nitrofurazone (Furacilin) is a topical anti-infective agent effective against gram-negative and gram-positive bacteria.</p>Fórmula:C6H6N4O4Pureza:99.87%Cor e Forma:Pale Yellow Needles Solution) 6 0 - 6 5 Alkaline Solutions Are Dark Orange (Ntp 1992)Peso molecular:198.14DS-1001b
CAS:<p>DS-1001b is an inhibitor of mutant IDH-1 (Isocitrate Dehydrogenase-1)</p>Fórmula:C29H29Cl3FN3O4Pureza:99.81%Cor e Forma:SolidPeso molecular:608.92Dihydrouracil
CAS:<p>5,6-Dihydrouracil (5,6-Dihydrouracil) is an intermediate breakdown product of uracil.</p>Fórmula:C4H6N2O2Pureza:99.75%Cor e Forma:SolidPeso molecular:114.1AZD7545
CAS:<p>AZD7545 is a potent PDHK inhibitor.</p>Fórmula:C19H18ClF3N2O5SPureza:99.12% - 99.96%Cor e Forma:SolidPeso molecular:478.87BI-187004
CAS:<p>BI-187004 is an 11β-hydroxysteroid dehydrogenase 1 inhibitor.</p>Fórmula:C21H18N4OPureza:98.63%Cor e Forma:SolidPeso molecular:342.39PfDHODH-IN-2
CAS:<p>PfDHODH-IN-2: powerful antimalarial, blocks PfDHODH (IC50: 1.11 μM), for malaria research.</p>Fórmula:C13H12ClNO3SPureza:98.9%Cor e Forma:SolidPeso molecular:297.76AGI-6780
CAS:<p>AGI-6780 is a potent and selective inhibitor of IDH2 R140Q mutant.</p>Fórmula:C21H18F3N3O3S2Pureza:98.19% - 99.7%Cor e Forma:SolidPeso molecular:481.51Nitrofen
CAS:<p>Nitrofen is a selective contact herbicide. Nitrofen is a protoporphyrinogen oxidase and retinal dehydrogenase inhibitor.</p>Fórmula:C12H7Cl2NO3Pureza:99.92%Cor e Forma:Less Crystals Or Black Solid Used As A Pre- Or Post-Emergence HerbicidePeso molecular:284.09LDHA-IN-4
CAS:<p>LDHA-IN-4 (AZ33) is an LDHA inhibitor. Binding affinity to 6-His-tagged human LDHA expressed in E.coli BL21 (DE3) by SPR analysis with an active value of 93 nM.</p>Fórmula:C25H27N3O6SPureza:98.17% - 99.68%Cor e Forma:SolidPeso molecular:497.56BVT 2733
CAS:<p>BVT 2733 is a new, non-steroidal, isoform-specific inhibitor of 11β-HSD1.</p>Fórmula:C17H21ClN4O3S2Pureza:98% - 99.64%Cor e Forma:SolidPeso molecular:428.96PfDHODH-IN-1
CAS:<p>PfDHODH-IN-1 is an inhibitor of Plasmodium falciparum dihydroorotate dehydrogenase(PfDHODH) which catalyzes the rate-limiting step for DNA and RNA biosynthesis.</p>Fórmula:C14H11F3N2O2Pureza:99.87%Cor e Forma:SolidPeso molecular:296.24AKR1C3-IN-1
CAS:<p>AKR1C3-IN-1 is a potent and selective inhibitor of AKR1C3(IC50 of 13 nM).</p>Fórmula:C16H15NO4SPureza:98.02%Cor e Forma:SolidPeso molecular:317.36AKR1C3-IN-4
CAS:<p>AKR1C3-IN-4: potent, selective AKR1C3 inhibitor, IC50 = 0.56 μM, potential for CRPC research.</p>Fórmula:C14H10F3NO2Pureza:98.59%Cor e Forma:SolidPeso molecular:281.23BMS-823778 hydrochloride
CAS:<p>BMS-823778 hydrochloride is a potent, selective, and orally active inhibitor of 11β-HSD1 (11β-Hydroxysteroid Dehydrogenase Type 1), demonstrating an IC50 (half</p>Fórmula:C18H19Cl2N3OCor e Forma:SolidPeso molecular:364.27G6PDi-1
CAS:<p>G6PDi-1 is an effective G6PD inhibitor. It depletes NADPH and decreases inflammatory cytokine production.</p>Fórmula:C14H12N4OSPureza:98.69%Cor e Forma:SolidPeso molecular:284.34R162
CAS:<p>R162 is an effective glutamate dehydrogenase 1 (GDH1) inhibitor.</p>Fórmula:C17H12O3Pureza:96.21% - 98.15%Cor e Forma:SolidPeso molecular:264.28(E/Z)-Teriflunomide
CAS:<p>(E/Z)-Teriflunomide (Aubagio), a orally-available Pyrimidine Synthesis Inhibitor, is used to treat relapsing multiple sclerosis.</p>Fórmula:C12H9F3N2O2Pureza:99.49% - 99.76%Cor e Forma:White SolidPeso molecular:270.21Brequinar
CAS:<p>Brequinar (NSC-368390) is a potent inhibitor of dihydroorotate dehydrogenase, with potent activities against a broad spectrum of viruses.</p>Fórmula:C23H15F2NO2Pureza:99.1% - 99.57%Cor e Forma:SolidPeso molecular:375.37PHGDH-inactive
CAS:<p>PHGDH inactive is inactive against PHGDH and serves as a negative control for NCT-502 and NCT-503 [1].</p>Fórmula:C17H21N5SPureza:99.83%Cor e Forma:SolidPeso molecular:327.45Carbenoxolone disodium
CAS:<p>Carbenoxolone disodium treats stomach ulcers; derived from licorice, often has antidiuretic effects, low toxicity.</p>Fórmula:C34H48Na2O7Pureza:99.69%Cor e Forma:SolidPeso molecular:614.72MK-8245
CAS:<p>MK-8245 is a liver-targeting SCD inhibitor for human SCD1 (IC50: 1 nM) and for rat/mouse SCD1 (IC50: 3 nM), with anti-diabetic and anti-dyslipidemic function.</p>Fórmula:C17H16BrFN6O4Pureza:97.58% - 99%Cor e Forma:SolidPeso molecular:467.25NCT-501 hydrochloride
CAS:<p>NCT-501 hydrochloride: potent, selective ALDH1A1 inhibitor based on theophylline; IC50 of 40 nM; highly discriminant against other ALDHs.</p>Fórmula:C21H33ClN6O3Cor e Forma:SolidPeso molecular:452.98Vidofludimus hemicalcium
CAS:Vidofludimus hemicalcium: oral DHODH inhibitor, FXR modulator, for autoimmune and fatty liver research.Fórmula:C20H18FNO4CaCor e Forma:SolidPeso molecular:375.4AG-636
CAS:<p>AG-636 is a potent, reversible, selective and orally active DHODH inhibitor(IC50 of 17 nM). It has strong anticancer effects.</p>Fórmula:C21H17N3O2Pureza:99.19%Cor e Forma:SolidPeso molecular:343.38Sodium dichloroacetate
CAS:<p>Sodium dichloroacetate (BCA) inhibits PDK (IC50: 183 μM PDK2, 80 μM PDK4), triggers cancer cell apoptosis, and impedes tumor growth.</p>Fórmula:C2HCl2NaO2Pureza:99.32% - 99.87%Cor e Forma:White PowderPeso molecular:150.92A939572
CAS:<p>A939572 is stearoyl-CoA desaturase1 (SCD1) inhibitor with IC50 values of <4 nM for mSCD1 and 37 nM for hSCD1.</p>Fórmula:C20H22ClN3O3Pureza:99.96% - ≥95%Cor e Forma:SolidPeso molecular:387.86Proguanil hydrochloride
CAS:<p>Proguanil hydrochloride, a biguanide, metabolizes into cycloguanil, an anti-malaria agent that inhibits plasmodium's DNA and protein synthesis.</p>Fórmula:C11H17Cl2N5Pureza:98.34% - 98.39%Cor e Forma:SolidPeso molecular:290.19Ivosidenib
CAS:<p>Ivosidenib (AG-120) is an oral IDH1 inhibitor targeting mutated IDH1 to reduce 2-hydroxyglutarate and hinder tumor growth.</p>Fórmula:C28H22ClF3N6O3Pureza:98.71% - 99.98%Cor e Forma:SolidPeso molecular:582.96Tiazofurin
CAS:<p>Tiazofurin, a synthetic nucleoside, has anti-cancer effects and inhibits IMPDH as TAD after metabolism.</p>Fórmula:C9H12N2O5SPureza:99.91%Cor e Forma:SolidPeso molecular:260.27Galloflavin
CAS:<p>Galloflavin is a lactate dehydrogenase inhibitor. Galloflavin inhibits both human LDH isoforms (type A and type B).Cost-effective and quality-assured.</p>Fórmula:C12H6O8Pureza:96.24% - 97.47%Cor e Forma:SolidPeso molecular:278.17NCT-505
CAS:<p>NCT-505 is a potent and selective inhibitor of aldehyde dehydrogenase (ALDH1A1, IC50 = 7 nM) and a weak inhibitor of hALDH1A2, hALDH1A3, hALDH2, hALDH3A1 with</p>Fórmula:C27H28FN5O3SPureza:99.93%Cor e Forma:SolidPeso molecular:521.61VER-246608
CAS:<p>VER-246608 inhibits PDK (IC50: 35-91 nM), boosts PDC, reduces glycolysis, causes cancer cell cytostasis, and enhances doxorubicin effects.</p>Fórmula:C28H23ClF2N4O4Pureza:98.5%Cor e Forma:SolidPeso molecular:552.96Mutant IDH1-IN-1
CAS:<p>Mutant IDH1-IN-1 is a potent mutant IDH1 R132 h inhibitor with IC50 < 0.1 uM.</p>Fórmula:C30H31FN4O2Pureza:99.49% - >99.99%Cor e Forma:SolidPeso molecular:498.59NCT-503
CAS:<p>NCT-503 is a phosphoglycerate dehydrogenase (PHGDH) inhibitor with no activity against other dehydrogenases. NCT-503 has antitumor activity. Cost-effective and quality-assured.</p>Fórmula:C20H23F3N4SPureza:98.91% - 99.84%Cor e Forma:SolidPeso molecular:408.48L-Allylglycine
CAS:<p>L-Allylglycine is a potent inhibitor of the synthetic enzyme for GABA, glutamic acid decarboxylase.</p>Fórmula:C5H9NO2Pureza:≥98%Cor e Forma:White To Off-White Crystalline PowderPeso molecular:115.13CM10
CAS:<p>CM10 is an aldehyde dehydrogenase 1A family(ALDH1A) inhibitor.</p>Fórmula:C20H23N3OPureza:99.84%Cor e Forma:SolidPeso molecular:321.42NCT-501
CAS:<p>NCT-501 is a potent and selective inhibitor of Aldehyde Dehydrogenase 1A1 (ALDH1A1) with IC50 of 40 nM.</p>Fórmula:C21H32N6O3Pureza:99.19%Cor e Forma:SolidPeso molecular:416.52AGI-5198
CAS:<p>AGI-5198 (IDH-C35) is a highly effective and specific inhibitor of IDH1 R132H/R132C mutants (IC50: 0.07/0.16 μM).</p>Fórmula:C27H31FN4O2Pureza:97.37% - 99.23%Cor e Forma:SolidPeso molecular:462.56Nifurtimox
CAS:<p>Nifurtimox (BAY-A-2502) is an antiprotozoal agent (IC50s = 9.91, 12.28, and 10.44 μM against Taluahuén, LQ, and Brener strains of T.</p>Fórmula:C10H13N3O5SPureza:99.87% - 99.89%Cor e Forma:SolidPeso molecular:287.29BAY-1436032
CAS:<p>BAY-1436032 is a novel, selective and orally available inhibitor of pan-mutant isocitrate dehydrogenase 1 (IDH1).</p>Fórmula:C26H30F3N3O3Pureza:99.65% - 99.71%Cor e Forma:SolidPeso molecular:489.53WIN 18446
CAS:<p>inhibitor of aldehyde dehydrogenase 1a2 (ALDH1a2)</p>Fórmula:C12H20Cl4N2O2Pureza:99.69%Cor e Forma:SolidPeso molecular:366.11Brequinar sodium
CAS:<p>Bipenquinate is a potent and selective inhibitor of dihydroorotate dehydrogenase (DHODH) with IC50 of 20 nM, blocking de novo pyrimidine biosynthesis.</p>Fórmula:C23H14F2NNaO2Pureza:98.16%Cor e Forma:SolidPeso molecular:397.36Fomepizole
CAS:<p>Fomepizole (4-Methylpyrazole), a competitive inhibitor of alcohol dehydrogenase, is used as an antidote in methanol or ethylene glycol poisoning.</p>Fórmula:C4H6N2Pureza:98.1% - 99.94%Cor e Forma:Yellow <13°C Solid >13°C LiquidPeso molecular:82.1Imidazole-5-propionic acid
CAS:<p>Imidazole-5-propionic acid (Imidazolylpropionic acid) is a product of histidine metabolism and may involve oxidation or transamination.</p>Fórmula:C6H8N2O2Pureza:99.62%Cor e Forma:SolidPeso molecular:140.14AG-120 (racemic)
CAS:<p>AG-120 (racemic) is an oral IDH1 inhibitor with potential anti-cancer effects.</p>Fórmula:C28H22ClF3N6O3Pureza:99.56%Cor e Forma:SolidPeso molecular:582.96Vidofludimus
CAS:<p>Vidofludimus (SC12267) (4SC-101, SC12267) is a novel small molecule inhibitor of dihydroorotate dehydrogenase (DHODH).</p>Fórmula:C20H18FNO4Pureza:98.33% - 99.58%Cor e Forma:SolidPeso molecular:355.36BVT-14225
CAS:<p>BVT-14225 is a selective 11β-Hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor (IC50=52 nM).</p>Fórmula:C16H20ClN3O3S2Pureza:97.78%Cor e Forma:SolidPeso molecular:401.93(R)-GNE-140
CAS:<p>(R)-GNE-140 (GNE-140) is an effective LDHA/LDHB inhibitor (IC50s: 3/5 nM) and is 18-fold more potent than S enantiomer.</p>Fórmula:C25H23ClN2O3S2Pureza:98.25% - 98.91%Cor e Forma:SolidPeso molecular:499.04Succinyl phosphonate trisodium salt
CAS:<p>Succinyl phosphonate trisodium salt is an inhibitor of α-ketoglutarate dehydrogenase (KGDHC)</p>Fórmula:C4H4Na3O6PPureza:99.8% - ≥95%Cor e Forma:SolidPeso molecular:248.01SW033291
CAS:<p>SW033291 is a small-molecule inhibitor of 15-PGDH (Ki=0.1 nM) that increases prostaglandin PGE2 levels in bone marrow and other tissues.</p>Fórmula:C21H20N2OS3Pureza:97.26% - 99.02%Cor e Forma:SolidPeso molecular:412.593-Hydroxybenzaldehyde
CAS:<p>3-Hydroxybenzaldehyde is a compound useful in organic synthesis.</p>Fórmula:C7H6O2Pureza:99.60%Cor e Forma:DrypowderPeso molecular:122.126PGD-IN-S3
CAS:<p>6PGD-IN-S3 (6PGD Inhibitor S3) is an inhibitor of 6-phosphogluconate dehydrogenase (6PGD).</p>Fórmula:C15H10O4Pureza:99.12%Cor e Forma:SolidPeso molecular:254.24Enasidenib
CAS:<p>Enasidenib (AG-221) is an orally available inhibitor of specific mutant forms of the mitochondrial enzyme isocitrate dehydrogenase type 2 (IDH2), with potential</p>Fórmula:C19H17F6N7OPureza:98% - >99.99%Cor e Forma:SolidPeso molecular:473.38Enasidenib mesylate
CAS:<p>Enasidenib mesylate (AG-221 mesylate) is a IDH2 inhibitor that promotes differentiation of leukemia myeloid cells for the treatment of acute myeloid leukemia.</p>Fórmula:C20H21F6N7O4SPureza:99.86%Cor e Forma:SolidPeso molecular:569.48DS44960156
CAS:<p>DS44960156 is an inhibitor of methylenetetrahydrofolate dehydrogenase 2 (MTHFD2) that inhibits both MTHFD2 and MTHFD1 and can be used in cancer research.</p>Fórmula:C20H15NO5Pureza:99.13%Cor e Forma:SolidPeso molecular:349.34GSK1940029
CAS:<p>GSK1940029 (SCD inhibitor 1) is a stearoyl-coa desaturase (SCD) inhibitor.</p>Fórmula:C18H16Cl2N4O2Pureza:99.48% - 99.49%Cor e Forma:SolidPeso molecular:391.25Triflupromazine
CAS:<p>Triflupromazine is a dopamine receptor D1/D2 antagonist and LHDA inhibitor that suppresses dopamine activity in (CNS)mental disorders, sedation, and antiemesis.</p>Fórmula:C18H19F3N2SCor e Forma:SolidPeso molecular:352.42hDHODH-IN-2
CAS:<p>hDHODH-IN-2: Leflunomide metabolite analog, inhibits human dihydroorotate dehydrogenase, anti-inflammatory.</p>Fórmula:C19H16N2O2Pureza:98%Cor e Forma:SolidPeso molecular:304.349Nitrophenide
CAS:<p>Nitrophenide, a 3,3'-Dinitrodiphenyl disulfide, blocks M1PDH in the mannitol cycle, serving as an anticoccidial.</p>Fórmula:C12H8N2O4S2Pureza:99.78%Cor e Forma:SolidPeso molecular:308.33AGI-14100
CAS:<p>AGI-14100 is a novel and orally available mIDH1 inhibitor.AGI-14100 is used for the treatment of primary human myeloid leukemia.</p>Fórmula:C29H22ClF4N5O3Pureza:99.91%Cor e Forma:SolidPeso molecular:599.96Epostane
CAS:<p>Epostane is a 3β-hydroxysteroid dehydrogenase inhibitor that blocks the biosynthesis of progesterone and pregnenolone.Cost-effective and quality-assured.</p>Fórmula:C22H31NO3Pureza:>99.99%Cor e Forma:SolidPeso molecular:357.49DHODH-IN-24
CAS:<p>DHODH-IN-24 (compound 16) serves as a powerful inhibitor of human dihydroorotate dehydrogenase (DHODH), exhibiting an IC50 value of 91 nM [1].</p>Fórmula:C26H26N4Cor e Forma:SolidPeso molecular:394.51IMB-XMA0038
CAS:<p>IMB-XMA0038 is a Mycobacterium tuberculosis aspartate semialdehyde dehydrogenase inhibitor with antimicrobial activity for use in tuberculosis research.</p>Fórmula:C11H10N4O6Pureza:98.94% - 99.96%Cor e Forma:SolidPeso molecular:294.22BI-4924
CAS:<p>BI-4924 is a PHGDH inhibitor that disrupts serine biosynthesis by intracellular trapping and can be used to study metabolic disorders.</p>Fórmula:C21H20Cl2N2O6SPureza:99.55%Cor e Forma:SolidPeso molecular:499.36NCT-506
CAS:<p>NCT-506 is an orally bioavailable inhibitors of aldehyde dehydrogenase 1A1 (ALDH1A1) (IC50 of 7 nM).</p>Fórmula:C25H23FN4O3SPureza:98%Cor e Forma:SolidPeso molecular:478.54SCH-451659
CAS:<p>SCH-451659 is an 17β-hydroxysteroid dehydrogenases (17β-HSDs) inhibitor.</p>Fórmula:C30H39Cl2N3O2Pureza:98%Cor e Forma:SolidPeso molecular:544.56BI-135585
CAS:<p>BI-135585 is an orally active, selective and potent inhibitor of human 11β-hydroxysteroid dehydrogenase-1 (HSD1) for the study of type 2 diabetes.</p>Fórmula:C28H32N2O4Pureza:99.45% - 99.57%Cor e Forma:SolidPeso molecular:460.57CM026
CAS:<p>CM026 inhibits ALDH1A1 selectively, binds to its aldehyde pocket uncompetitively.</p>Fórmula:C22H30N6O4Cor e Forma:SolidPeso molecular:442.51ML387
CAS:<p>ML387 is an inhibitor of human NAD(+)- dependent 15- hydroxyprostaglandin dehydrogenase.</p>Fórmula:C20H21N3O2Pureza:98%Cor e Forma:SolidPeso molecular:335.4Oxycinchophen
CAS:<p>Oxycinchophen: Quinoline-based anti-rheumatic with P-selectin inhibition, DHOD blockade, and anti-inflammatory impacts on vascular muscle.</p>Fórmula:C16H11NO3Pureza:98%Cor e Forma:SolidPeso molecular:265.26GW648495
CAS:<p>GW648495 is a PfDHODH inhibitor that shows greater than 4,000-fold selectivity for the malarial enzyme.</p>Fórmula:C16H13N5Pureza:98%Cor e Forma:SolidPeso molecular:275.31BVT-116429
CAS:<p>BVT-116429 is an inhibitor of 11β-HSD1.</p>Fórmula:C13H12F4N2OSPureza:98%Cor e Forma:SolidPeso molecular:320.31GA11
CAS:<p>GA11is an inhibitor of ALDH1. It also displays anti-GBM effects in vitro and in vivo.</p>Fórmula:C19H14N2Pureza:98%Cor e Forma:SolidPeso molecular:270.33RS6212
CAS:<p>RS6212 is a specific lactate dehydrogenase (LDH) inhibitor (IC50=12.03 μ M）。 RS6212 shows strong anticancer activity in a variety of cancer cell lines.</p>Fórmula:C20H22N4O3SCor e Forma:SolidPeso molecular:398.48RORγt/DHODH-IN-2
CAS:<p>RORγt/DHODH-IN-2 (compound 1) is a potent dual RORγt/DHODH inhibitor that can be used in the study of inflammatory bowel disease (IBD).</p>Fórmula:C25H30N4OSCor e Forma:SolidPeso molecular:434.6UCK2 Inhibitor-2
CAS:<p>UCK2 Inhibitor-2 is a non-competitive inhibitor of uridine-cytidine kinase 2 (UCK2) with IC50=3.8 µM that inhibits UCK2-mediated nucleoside recycling in cells.</p>Fórmula:C28H23N3O4SPureza:98.76% - 99.25%Cor e Forma:SolidPeso molecular:497.57DHODH-IN-20
CAS:<p>Dhodh-in-20 (Compound 133), a potent DHODH inhibitor, may help study acute myeloid leukemia and inhibit tumor growth.</p>Fórmula:C24H25F4N3O3Cor e Forma:SolidPeso molecular:479.47hDHODH-IN-4
CAS:<p>hDHODH-IN-4, a potent DHODH inhibitor, has a pIC50 of 7.8 and blocks measles virus replication with a pMIC50 of 8.8.</p>Fórmula:C21H24N4O2Pureza:99.87%Cor e Forma:SolidPeso molecular:364.44ALDH1A1-IN-3
CAS:<p>ALDH1A1-IN-3 selectively inhibits ALDH1A1, enhances HepG2 glucose consumption for metabolic research.</p>Fórmula:C31H36F3N5O4Cor e Forma:SolidPeso molecular:599.64AZD8329
CAS:<p>AZD8329 is an 11β-HSD1 inhibitor that inhibits 11β-HSD2, 17β-HSD1, 17β-HSD3, and can be used to study allergic reactions in humans.</p>Fórmula:C25H31N3O3Pureza:99.31%Cor e Forma:SolidPeso molecular:421.53KM04416
CAS:<p>KM04416 is a GPD2 inhibitor that inhibits LUAD progression by modulating immune cell infiltration.</p>Fórmula:C12H11NO3SPureza:99.88%Cor e Forma:SolidPeso molecular:249.29ALDH1A1-IN-2
CAS:<p>ALDH1A1-IN-2 is an aldehyde dehydrogenase 1a1 inhibitor with anticancer activity.ALDH1A1-IN-2 may be used in the study of breast cancer, inflammation or obesity</p>Fórmula:C25H23ClN4O3SPureza:99.48%Cor e Forma:SolidPeso molecular:494.99Laflunimus
CAS:<p>Laflunimus (HR325) is a DHODH inhibitor that inhibits immunoglobulin secretion in vitro and in vivo,by interfering with pyrimidine metabolism,neuralgia.</p>Fórmula:C15H13F3N2O2Pureza:99.86%Cor e Forma:SolidPeso molecular:310.27hDHODH-IN-9
CAS:<p>hDHODH-IN-9 is a potent hDHODH inhibitor, IC50=0.34 μM, toxic to MCF-7/A375 cells, promising for cancer research.</p>Fórmula:C21H21NO4Cor e Forma:SolidPeso molecular:351.4RV01
CAS:<p>RV01, a resveratrol-like quinoline, inhibits DNA damage, ALDH2 expression, and has antioxidant and anti-inflammatory properties.</p>Fórmula:C17H13NO2Pureza:99.93%Cor e Forma:SolidPeso molecular:263.29hDHODH-IN-3
CAS:<p>hDHODH-IN-3 is an inhibitor of human dihydroorotate dehydrogenase with a pMIC50 value of 8.6. hDHODH-IN-3 can inhibit measles virus replication.</p>Fórmula:C18H19BrN4O2Pureza:99.871%Cor e Forma:SolidPeso molecular:403.27Genz-669178
CAS:<p>Genz-669178 is a wild-type inhibitor of Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH).</p>Fórmula:C17H14N4OSPureza:98%Cor e Forma:SolidPeso molecular:322.38EN40
CAS:<p>EN40, as a covalent ligand, is a selective inhibitor of aldehyde dehydrogenase 3A1 (IC50: 2 uM).</p>Fórmula:C13H15NO2Cor e Forma:SolidPeso molecular:217.26DHODH-IN-13
CAS:<p>DHODH-IN-13 is an inhibitor of DHODH with IC50 of 4.3 μM for rat liver. DHODH-IN-13 can be used in studies about rheumatoid arthritis.</p>Fórmula:C10H6F3N3O3Pureza:99.66%Cor e Forma:SolidPeso molecular:273.17DHODH-IN-15
CAS:<p>DHODH-IN-15, a hydroxyfuran analogue of A771726, inhibits rat liver DHODH with an IC50 of 11 μM, and is used for rheumatoid arthritis.</p>Fórmula:C15H11N3O3Pureza:99.8%Cor e Forma:SolidPeso molecular:281.27DHODH-IN-17
CAS:<p>DHODH-IN-17 is a human DHODH inhibitor with an IC50 of 0.40 μM.</p>Fórmula:C12H9ClN2O2Pureza:99.41% - 99.52%Cor e Forma:SolidPeso molecular:248.67DHODH-IN-1
CAS:<p>DHODH-IN-1 is a potent dihydroorotate dehydrogenase (DHODH) inhibitor with IC50 of 25 nM. DHODH-IN-1 is an inhibitor of the pyrimidine biosynthetic pathway.</p>Fórmula:C21H20F3N3O2Pureza:99.76%Cor e Forma:SolidPeso molecular:403.4hDHODH-IN-5
CAS:<p>hDHODH-IN-5 is an inhibitor of human dihydroorotate dehydrogenase (hDHODH, IC50 = 0.91 μM).</p>Fórmula:C21H21F3N2O2Pureza:99.55%Cor e Forma:SolidPeso molecular:390.4p-Valerylphenol
CAS:<p>p-Valerylphenol (NSC-49186) can be used to synthesize acylphenoxyacetic acid compounds.</p>Fórmula:C11H14O2Pureza:99.87%Cor e Forma:White To Light Beige PowderPeso molecular:178.23M77976
CAS:<p>M77976 inhibits PDK4 with an IC50 of 648 μM, targeting obesity and diabetes research.</p>Fórmula:C17H16N2O3Pureza:99.43%Cor e Forma:SolidPeso molecular:296.32Manitimus
CAS:<p>Manitimus is a potent immunosuppressive drug, and is an inhibitor of dehydroorotate dehydrogenase,.</p>Fórmula:C15H11F3N2O2Pureza:99.75% - 99.75%Cor e Forma:SolidPeso molecular:308.26Metapramine
CAS:<p>Metapramine, a tricyclic antidepressant, blocks norepinephrine reuptake and is a low-affinity NMDA antagonist.</p>Fórmula:C16H18N2Pureza:99.03% - 99.67%Cor e Forma:SolidPeso molecular:238.3311β-HSD1-IN-1
CAS:<p>11β-HSD1-IN-1 is an inhibitor of 11β-hydroxydehydrogenase 1 (11β-HSD1, IC50: 52 nM), and used for the treatment of pain.</p>Fórmula:C18H14ClF4N3OPureza:99.84%Cor e Forma:SolidPeso molecular:399.77DHODH-IN-4
CAS:<p>DHODH-IN-4 inhibits human & Plasmodium DHODH; IC50: 4 μM (Pf), 0.18 μM (Hs). It has antimalarial properties.</p>Fórmula:C17H12Cl2N2O2Pureza:99.34%Cor e Forma:SolidPeso molecular:347.2DHODH-IN-8
CAS:<p>DHODH-IN-8 is a DHODH inhibitor with antimalarial properties, IC50: 0.13 μM (human), 47.4 μM (P. falciparum); Ki: 0.016 μM (human), 5.6 μM (P. falciparum).</p>Fórmula:C17H13ClN2O2Pureza:99.78%Cor e Forma:SolidPeso molecular:312.7511β-HSD1-IN-12
CAS:<p>11β-HSD1-IN-12 is an 11β-HSD1 inhibitor.11β-HSD1-IN-12 is implicated in the conversion of glucocorticoids in vivo and can be used to study metabolic syndrome</p>Fórmula:C19H27ClN2O3SPureza:99.68%Cor e Forma:SolidPeso molecular:398.95Nitrefazole
CAS:<p>Nitrefazole: a 4-nitroimidazole, inhibits ALDH enzyme crucial for alcohol metabolism, has potent, durable effects.</p>Fórmula:C10H8N4O4Cor e Forma:SolidPeso molecular:248.1911β-HSD1-IN-6
CAS:<p>11β-HSD1-IN-6 is a potent inhibitor of 11β hydroxysteroid dehydrogenase enzymes (11β-HSDs).</p>Fórmula:C21H19ClN4OCor e Forma:SolidPeso molecular:378.86CM39
CAS:<p>CM39 inhibits ALDH, linked to cancer stem-like cells & chemoresistance.</p>Fórmula:C19H15FN4OSCor e Forma:SolidPeso molecular:366.41MEDS433
CAS:<p>MEDS433 inhibits dihydroorotate dehydrogenase (IC50 1.2 nM) and blocks replication of hCoV-OC43, hCoV-229E, SARS-CoV-2 at nanomolar levels.</p>Fórmula:C20H11F4N3O2Cor e Forma:SolidPeso molecular:401.31hDHODH-IN-11
CAS:<p>hDHODH-IN-11: potent hDHODH inhibitor, IC50 7.2 nM, low cytotoxicity, for AML research.</p>Fórmula:C24H23N3O3Cor e Forma:SolidPeso molecular:401.46DHODH-IN-12
CAS:<p>DHODH-IN-12 is a leflunomide derivative and a weak dihydrorotate dehydrogenase (DHODH) inhibitor with a pKa of 5.07.</p>Fórmula:C10H9N3O2Pureza:99.53%Cor e Forma:SolidPeso molecular:203.2AMG-221
CAS:<p>AMG-221: potent 11β-HSD1 inhibitor, lowers glucose & insulin, reduces obesity in mice.</p>Fórmula:C14H22N2OSPureza:98%Cor e Forma:SolidPeso molecular:266.411β-HSD1-IN-10
CAS:<p>11β-HSD1-IN-10, a potent inhibitor of 11β-HSD1 with an IC50 value of 1.8 µM for humans, is suitable for research into obesity, hyperglycemia, and cognitive</p>Fórmula:C16H10F3NO2Cor e Forma:SolidPeso molecular:305.25673-A
CAS:<p>673-A inhibits ALDH1A, depletes ovarian CSCs, induces necroptosis, and reverses chemo resistance.</p>Fórmula:C15H13NOCor e Forma:SolidPeso molecular:223.27DHODH-IN-19
CAS:<p>DHODH-IN-19, a strong DHODH blocker, may help treat cancer and inflammation. (Patent WO2021238881A1)</p>Fórmula:C22H18ClF6N3O3Cor e Forma:SolidPeso molecular:521.84ASP3662
CAS:<p>ASP3662/SPI-62: Potent, selective CNS-penetrable 11β-HSD1 inhibitor; potential neuropathic pain treatment.</p>Fórmula:C19H16ClF3N4O2Cor e Forma:SolidPeso molecular:424.8TM-1
CAS:<p>TM-1: PDHK inhibitor, IC50 - PDHK1: 2.97μM, PDHK2: 5.2μM, prevents PDHC phosphorylation, inhibits cancer cell growth.</p>Fórmula:C26H32N2O6Cor e Forma:SolidPeso molecular:468.54DHODH-IN-3
CAS:<p>DHODH-IN-3: Human DHODH inhibitor with IC50 of 261 nM, Kiapp 32 nM, potential anti-malaria drug.</p>Fórmula:C17H13ClN2O2Pureza:98%Cor e Forma:SolidPeso molecular:312.75ALDH3A1-IN-2
CAS:<p>ALDH3A1-IN-2 is a potent inhibitor targeting ALDH3A1 (IC50=1.29µM), potentially useful in cancer research.</p>Fórmula:C11H14N2O3Cor e Forma:SolidPeso molecular:222.2411β-HSD1-IN-9
CAS:<p>11β-HSD1-IN-9 is a potent inhibitor of 11β-HSD1, displaying IC50 values of 0.48 µM for human and 1.3 µM for murine variants, respectively.</p>Fórmula:C13H9F3N2OCor e Forma:SolidPeso molecular:266.22DHODH-IN-21
CAS:<p>DHODH-IN-21, orally active DHODH blocker with 1.1 nM IC50, shows anticancer activity, potential for AML research.</p>Fórmula:C20H19ClF4N6O4Cor e Forma:SolidPeso molecular:518.85BRD9185
CAS:<p>BRD9185 is an inhibitor of Dihydroorotate dehydrogenase (DHODH) with an EC50 of 16 nM against multidrug-resistant blood-stage parasites in vitro.</p>Fórmula:C23H21F6N3O2Pureza:98%Cor e Forma:SolidPeso molecular:485.42P1788
CAS:<p>P1788 is a dihydroorotate dehydrogenase (DHODH) inhibitor that can induce DNA damage [1].</p>Fórmula:C15H17NO3Cor e Forma:SolidPeso molecular:259.3
