Proteases/Proteassoma
Os inibidores de proteases e proteassomas são compostos que bloqueiam a atividade das proteases e do proteassoma, que estão envolvidos na degradação e renovação de proteínas. Esses inibidores são vitais para estudar a regulação da homeostase de proteínas, controle do ciclo celular e apoptose. Inibidores de proteases e proteassomas também são utilizados no tratamento de doenças como o câncer, onde a degradação anormal de proteínas desempenha um papel na progressão da doença. Ao inibir proteases ou o proteassoma, esses compostos podem induzir a morte celular em células cancerígenas e são ferramentas essenciais tanto na pesquisa básica quanto no desenvolvimento terapêutico. Na CymitQuimica, oferecemos uma ampla gama de inibidores de proteases e proteassomas de alta qualidade para apoiar sua pesquisa em bioquímica, biologia celular e desenvolvimento de medicamentos.
Subcategorias de "Proteases/Proteassoma"
- Acetil- CoA Carboxilase(38 produtos)
- Cisteína Protease(111 produtos)
- DPP-4(27 produtos)
- Glutaminase(46 produtos)
- HIV Protease(507 produtos)
- PAI-1(26 produtos)
- Inibidores de Protease(50 produtos)
- Receptor activado por protease(55 produtos)
- Proteassoma(86 produtos)
- Protease serina(54 produtos)
- p97(15 produtos)
Exibir 3 mais subcategorias
Foram encontrados 977 produtos de "Proteases/Proteassoma"
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Nelfinavir Mesylate
CAS:Fórmula:C32H45N3O4S·CH4O3SPureza:>97.0%(HPLC)Cor e Forma:White to Almost white powder to crystalPeso molecular:663.89Limonin
CAS:Fórmula:C26H30O8Pureza:>95.0%(HPLC)Cor e Forma:White to Almost white powder to crystalPeso molecular:470.524-(2-Aminoethyl)benzenesulfonyl Fluoride Hydrochloride [for Biochemical Research]
CAS:Fórmula:C8H10FNO2S·HClPureza:>99.0%(HPLC)Cor e Forma:White to Almost white powder to crystalPeso molecular:239.69Atazanavir Sulfate
CAS:Fórmula:C38H52N6O7·H2SO4Pureza:>98.0%(HPLC)Cor e Forma:White to Almost white powder to crystalPeso molecular:802.94Camostat Mesylate
CAS:Fórmula:C20H22N4O5·CH4O3SPureza:>98.0%(HPLC)Cor e Forma:White to Almost white powder to crystalPeso molecular:494.52Disodium Dihydrogen Ethylenediaminetetraacetate Dihydrate [for Biochemical Research]
CAS:Fórmula:C10H14N2Na2O8·2H2OPureza:>99.0%(T)Cor e Forma:White powder to crystalinePeso molecular:372.24Ritonavir
CAS:Fórmula:C37H48N6O5S2Pureza:>98.0%(HPLC)(N)Cor e Forma:White to Almost white powder to crystalinePeso molecular:720.95Benzamidine Hydrochloride [for Biochemical Research]
CAS:Fórmula:C7H8N2·HClPureza:>95.0%(T)(N)Cor e Forma:White to Almost white powder to crystalPeso molecular:156.61Benzylsulfonyl Fluoride [for Biochemical Research]
CAS:Fórmula:C7H7FO2SPureza:>98.0%(GC)Cor e Forma:White to Almost white powder to crystalPeso molecular:174.191,10-Phenanthroline Monohydrate [for Biochemical Research]
CAS:Fórmula:C12H8N2·H2OPureza:>99.0%(T)Cor e Forma:White powder to crystalPeso molecular:198.232-Iodoacetamide [for Biochemical Research]
CAS:Fórmula:C2H4INOPureza:>98.0%(N)Cor e Forma:White to Light yellow powder to crystalPeso molecular:184.96Gabexate Mesylate
CAS:Fórmula:C16H23N3O4·CH4O3SPureza:>97.0%(N)Cor e Forma:White to Almost white powder to crystalPeso molecular:417.48Nafamostat Mesylate
CAS:Fórmula:C19H17N5O2·2CH4O3SPureza:>98.0%(HPLC)Cor e Forma:White to Almost white powder to crystalPeso molecular:539.58Ethylene Glycol Bis(2-aminoethyl Ether)-N,N,N',N'-tetraacetic Acid [for Biochemical Research]
CAS:Fórmula:C14H24N2O10Pureza:>95.0%(T)Cor e Forma:White to Almost white powder to crystalPeso molecular:380.35Atazanavir
CAS:Fórmula:C38H52N6O7Pureza:>95.0%(HPLC)Cor e Forma:White to Light yellow powder to crystalPeso molecular:704.87Incyclinide
CAS:Incyclinide (COL-3) is a matrix metalloproteinase (MMP) inhibitor.Fórmula:C19H17NO7Pureza:97.99%Cor e Forma:SolidPeso molecular:371.34Ref: TM-T15574
1mg84,00€2mg89,00€1mL*10mM (DMSO)90,00€5mg113,00€10mg178,00€25mg371,00€50mg573,00€100mg802,00€200mg1.099,00€Gly-Pro-pNA hydrochloride
CAS:Gly-Pro-pNA hydrochloride (Gly-Pro p-nitroanilide hydrochloride) is a dipeptidyl peptidase inhibitor that inhibits dipeptidyl peptidase II, dipeptidyl peptidaseFórmula:C13H17ClN4O4Pureza:99.84%Cor e Forma:SolidPeso molecular:328.75Saxagliptin hydrate
CAS:Saxagliptin hydrate (Onglyza hydrate) is a selective and reversible DPP4 inhibitor (IC50: 26 nM; Ki: 1.3 nM).Fórmula:C18H25N3O2·H2OPureza:99.52%Cor e Forma:SolidPeso molecular:333.43(ETHYLENEDINITRILO)TETRAACETIC ACID, TRISODIUM SALT HYDRATE
CAS:Fórmula:C10H18N2NaO9Pureza:97%Cor e Forma:SolidPeso molecular:333.2477Ethylenediaminetetraacetic acid disodium salt dihydrate
CAS:Fórmula:C10H18N2Na2O10Pureza:97%Cor e Forma:SolidPeso molecular:372.2369L-Leucinamide, N-[(phenylmethoxy)carbonyl]-L-leucyl-N-[(1S)-1-formyl-3-methylbutyl]-
CAS:Fórmula:C26H41N3O5Pureza:98%Cor e Forma:SolidPeso molecular:475.6208Ref: IN-DA0072SK
1gA consultar500mgA consultar5mg68,00€10mg90,00€25mg124,00€50mg168,00€100mg229,00€250mg500,00€Benzenemethanesulfonyl fluoride
CAS:Fórmula:C7H7FO2SPureza:99%Cor e Forma:SolidPeso molecular:174.1927Benzoic acid, 4-[(aminoiminomethyl)amino]-, 6-(aminoiminomethyl)-2-naphthalenyl ester, dimethanesulfonate
CAS:Fórmula:C20H21N5O5SPureza:98%Cor e Forma:SolidPeso molecular:443.4762Sofosbuvir impurity G
CAS:Sofosbuvir impurity G is both a diastereomer of Sofosbuvir and an impurity of Sofosbuvir which is an inhibitor of HCV RNA replication.Fórmula:C22H29FN3O9PPureza:98.04%Cor e Forma:SolidPeso molecular:529.45Ref: TM-T12962
1mg1.044,00€5mg2.412,00€1mL*10mM (DMSO)3.033,00€10mg3.267,00€25mg4.851,00€50mg6.561,00€BAY-85-8501
CAS:BAY-85-8501 is a selective, reversible and potent inhibitor of Human Neutrophil Elastase (HNE; IC50 of 65 pM)Fórmula:C22H17F3N4O3SPureza:99.16%Cor e Forma:SolidPeso molecular:474.46Ref: TM-T12613L
1mg92,00€2mg122,00€5mg200,00€1mL*10mM (DMSO)208,00€10mg298,00€25mg535,00€50mg750,00€100mg1.035,00€Sofosbuvir impurity F
CAS:Sofosbuvir impurity F (Sofosbuvir 3',5'-Bis-(S)-phosphate) is both a diastereomer of Sofosbuvir and an impurity of Sofosbuvir which is an inhibitor of HCV RNAFórmula:C34H45FN4O13P2Pureza:98.05%Cor e Forma:SolidPeso molecular:798.69CL-82198
CAS:CL-82198, a selective MMP-13 inhibitor, serves as a pharmacological intervention to halt the progression of osteoarthritis (OA).Fórmula:C17H22N2O3Pureza:95.91%Cor e Forma:SolidPeso molecular:302.37Ref: TM-T14978
5mg44,00€1mL*10mM (DMSO)48,00€10mg70,00€25mg144,00€50mg230,00€100mg358,00€200mg523,00€500mg822,00€Benzoic acid, 4-[[6-[(aminoiminomethyl)amino]-1-oxohexyl]oxy]-, ethylester, monomethanesulfonate
CAS:Fórmula:C17H27N3O7SPureza:98%Cor e Forma:SolidPeso molecular:417.4772Dabigatran ethyl ester hydrochloride
CAS:Dabigatran prevents blood clots, inhibiting NQO2 and thrombin with IC50 0.8 μM.Fórmula:C27H30ClN7O3Pureza:99.65%Cor e Forma:SolidPeso molecular:536.03PMSF
CAS:PMSF (Phenylmethylsulfonyl fluoride) is an irreversible inhibitor of serine/cysteine protease , preparation of cell lysates. High-Quality, Low-Cost!Fórmula:C7H7FO2SPureza:97.75% - 99.88%Cor e Forma:White To Cream SolidPeso molecular:174.19RA190
CAS:RA190 inhibits proteasome function by covalently binding to cysteine 88 of ubiquitin receptor RPN13.Fórmula:C28H23Cl5N2O2Pureza:97.7%Cor e Forma:SolidPeso molecular:596.76Ref: TM-T13858
1mg54,00€5mg109,00€1mL*10mM (DMSO)142,00€10mg159,00€25mg233,00€50mg414,00€100mg608,00€DBPR108
CAS:DBPR108 is an orally bioavailable dipeptide-derived DPP4 inhibitor (IC50: 15 nM) and it has no inhibition on DDP8 and DPP9.Fórmula:C16H25FN4O2Pureza:99.68%Cor e Forma:SolidPeso molecular:324.39Ref: TM-T15079
1mg48,00€5mg100,00€1mL*10mM (DMSO)110,00€10mg133,00€25mg215,00€50mg306,00€100mg414,00€200mg573,00€HCV-IN-29
CAS:HCV-IN-29 is a hepatitis C virus (HCV) inhibitor.Fórmula:C26H32Cl4N6Pureza:99.89%Cor e Forma:SolidPeso molecular:570.38Bivalirudin acetate
Bivalirudin acetate is a thrombin inhibitor, a peptide-based anticoagulant, used for research on acute coronary syndrome.Fórmula:C100H142N24O35Pureza:99.84%Cor e Forma:SolidPeso molecular:2240.34Levovirin
CAS:Levovirin (L-Ribavirin) is a guanosine nucleoside analog that has immunomodulatory activity and is used in the study of hepatitis C virus infection.Fórmula:C8H12N4O5Pureza:99.81% - >99.99%Cor e Forma:SolidPeso molecular:244.20Ref: IN-DA00BBLC
100gA consultar5mg30,00€10mg30,00€50mg30,00€100mg37,00€250mg44,00€1g57,00€5g128,00€25g262,00€KW-2450 Formate
KW-2450 Formate is an IGF-1R/IR tyrosine kinase inhibitor with antitumor effects that acts through inhibition of Aurora A and B kinases.KW-2450 Formate inhibits the growth of TNBC xenografts and induces tetraploid accumulation.Fórmula:C29H31N5O5SPureza:99.28%Cor e Forma:SolidPeso molecular:561.65Ref: IN-DA0032JK
10kgA consultar5g22,00€10g26,00€25g30,00€50g40,00€100g59,00€250g98,00€500g153,00€1kg229,00€(2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanamido]-4-methylpentanoic acid
CAS:Fórmula:C16H24N2O4Pureza:98%Cor e Forma:SolidPeso molecular:308.3728Ref: IN-DA00370Q
25gA consultar10mg29,00€50mg34,00€100mg44,00€250mg68,00€1g132,00€5g223,00€10g532,00€N-Tosyl-L-phenylalanine chloromethyl ketone
CAS:Fórmula:C17H18ClNO3SPureza:97%Cor e Forma:SolidPeso molecular:351.8477Mecarbinate
CAS:Mecarbinate (Dimecarbin) is arbidol hydrochloride's chemical intermediate.Fórmula:C13H15NO3Pureza:99.28%Cor e Forma:Off-White Crystalline PowderPeso molecular:233.263-Isoquinolinecarboxamide, N-(1,1-dimethylethyl)decahydro-2-[(2R,3R)-2-hydroxy-3-[(3-hydroxy-2-methylbenzoyl)amino]-4-(phenylthio)butyl]-, (3S,4aS,8aS)-
CAS:Fórmula:C32H45N3O4SPureza:98%Cor e Forma:SolidPeso molecular:567.7824ARP-100
CAS:ARP-100 (MMP-2 Inhibitor III) is a potent and selective matrix metalloproteinase MMP-2 inhibitor (IC50=12 nM).Fórmula:C17H20N2O5SPureza:97.18%Cor e Forma:SolidPeso molecular:364.42(Rac)-Telinavir
CAS:N1 compound with anti-HIV activity; contains dimethyl, phenyl, quinoline groups.
Fórmula:C33H44N6O5Pureza:99.30%Cor e Forma:SolidPeso molecular:604.744-(2-Aminoethyl)benzenesulfonyl fluoride, HCl
CAS:Fórmula:C8H11ClFNO2SPureza:98%Cor e Forma:SolidPeso molecular:239.6948Dabigatran etexilate
CAS:Dabigatran etexilate (BIBR 1048) is a thrombin inhibitor, which acts by binding and blocking thrombogenic activity and the prevention of thrombus formation.Fórmula:C34H41N7O5Pureza:98.19% - 99.98%Cor e Forma:White PowderPeso molecular:627.73Ref: IN-DA0034HK
5gA consultar50kgA consultar10g21,00€25g25,00€50g25,00€100g34,00€250g60,00€500g75,00€1kg124,00€5kg563,00€3-Aminopropionitrile fumarate (2:1)
CAS:3-Aminopropionitrile fumarate (2:1) (β-Aminopropionitrile fumarate) is an organic compound and antirheumatic agent used in veterinary medicine.Fórmula:C4H4O4·2C3H6N2Pureza:99.76% - 99.79%Cor e Forma:White Crystalline PowderPeso molecular:256.26Ethylene glycol bis(2-aminoethyl ether)-N,N,N',N'-tetraacetic acid
CAS:Fórmula:C14H24N2O10Pureza:97%Cor e Forma:SolidPeso molecular:380.3478Begelomab
CAS:Begelomab (SAND-26) is a mouse-derived monoclonal antibody targeting DPP-4/CD26. Begelomab can be used to study severe refractory inflammatory myopathies.Pureza:97.8% (SDS-PAGE); 98.3% (SEC-HPLC) - 97.8% (SDS-PAGE); 98.3% (SEC-HPLC)Cor e Forma:LiquidPeso molecular:146.20 kDaMK-0608
CAS:MK-0608 is an orally bioavailable HCV replication inhibitor in vitro(EC50 = 0.3 μM and EC90=1.3 μM in the subgenomic-replicon assay).Fórmula:C12H16N4O4Pureza:98.48%Cor e Forma:SolidPeso molecular:280.28Ref: TM-T16088
1mg46,00€2mg59,00€1mL*10mM (DMSO)92,00€5mg96,00€10mg133,00€25mg250,00€50mg411,00€100mg660,00€DPP-IV-IN-2
CAS:DPP-IV-IN-2 (H-Lys(4-nitro-Z)-pyrrolidide) is an inhibitor of both DP8/9 and dipeptidyl peptidase IV (IC50s: 0.1 and 0.95 μM).Fórmula:C18H26N4O5Pureza:99.08%Cor e Forma:SolidPeso molecular:378.422-Oxiranecarboxylic acid, 3-[[[(1S)-3-methyl-1-[[(3-methylbutyl)amino]carbonyl]butyl]amino]carbonyl]-, ethyl ester, (2S,3S)-
CAS:Fórmula:C17H30N2O5Pureza:98%Cor e Forma:SolidPeso molecular:342.4305LSP-249
CAS:LSP-249 is a plasma kallikrein inhibitor under the study for angioedema, with an EC50 less than 100 nM in cell.Fórmula:C24H22ClN5OPureza:99.51%Cor e Forma:SolidPeso molecular:431.92LDN-27219
CAS:LDN-27219 is a potent hTGase inhibitor with IC50 of 0.6 uM.Fórmula:C20H16N4O2S2Pureza:99.01% - 99.38%Cor e Forma:SolidPeso molecular:408.5Ref: TM-T11831
1mg34,00€5mg63,00€1mL*10mM (DMSO)67,00€10mg96,00€25mg152,00€50mg221,00€100mg334,00€200mg489,00€IMAB027
CAS:Naratuximab (Anti-TSPAN26/CD37 Reference Antibody) is a humanized monoclonal antibody against CD37 that can be used to synthesize ADC compounds.Pureza:97.7% (SDS-PAGE); 97.5% (SEC-HPLC) - 97.7% (SDS-PAGE); 97.5% (SEC-HPLC)Cor e Forma:LiquidPeso molecular:144.42 kDaTrelagliptin
CAS:Trelagliptin (SYR-472) is a highly specific and long-acting DPP-4 inhibitor.Fórmula:C18H20FN5O2Pureza:98.88%Cor e Forma:SolidPeso molecular:357.38BJJF078
CAS:BJJF078, an aminopiperidine, inhibits human/mouse TG2 (IC50: 41/54 nM) and TG1 (IC50: 0.16 μM), may be used in MS studies.Fórmula:C27H29N3O6SPureza:99.56%Cor e Forma:SoildPeso molecular:523.6RAMB4
CAS:RAMB4 (PTP1B-IN-9) is a ubiquitin-proteasome system (UPS)-stressor,with anticancer activity.Fórmula:C19H13Cl4NOPureza:98.89% - 99.38%Cor e Forma:SolidPeso molecular:413.12Ruzasvir
CAS:Ruzasvir (MK-8408) is a novel and potent pan-genotypic inhibitor of hepatitis C virus NS5A with antiviral activity.Fórmula:C49H55FN10O7SPureza:96.87% - 99.93%Cor e Forma:SolidPeso molecular:947.09Avoralstat
CAS:Avoralstat (BCX4161) is an oral plasma kallikrein (PKK) inhibitor. Which is used for the treatment of hereditary angioedema.Fórmula:C28H27N5O5Pureza:99.77%Cor e Forma:SolidPeso molecular:513.54ML604440
CAS:ML604440 is a cell permeable proteasome β1i (LMP2) subunit inhibitor.Fórmula:C17H24BF3N2O4Pureza:97.06%Cor e Forma:SolidPeso molecular:388.19Ref: TM-T12079
1mg109,00€2mg158,00€5mg259,00€1mL*10mM (DMSO)285,00€10mg409,00€25mg677,00€50mg954,00€100mg1.288,00€200mg1.728,00€Dolutegravir intermediate-1
CAS:Dolutegravir intermediate-1 is a synthetic precursor for HIV-1 treatment from patent WO 2016125192 A2.Fórmula:C13H17NO8Pureza:99.52%Cor e Forma:SolidPeso molecular:315.28Retagliptin Phosphate
CAS:Retagliptin Phosphate (SP 2086) is pharmaceutical composition of DPP-4 inhibitor, for treating type-2 diabetes.Fórmula:C19H21F6N4O7PPureza:98.70%Cor e Forma:SolidPeso molecular:562.36Ref: TM-T12710
100mgA consultar1mg34,00€2mg42,00€5mg60,00€1mL*10mM (DMSO)79,00€10mg87,00€25mg161,00€50mg245,00€BLT-1
CAS:BLT-1 is a scavenger receptor BI (SR-BI)inhibitor.Fórmula:C12H23N3SPureza:97.97%Cor e Forma:SolidPeso molecular:241.4Ref: TM-T14667
1mg43,00€2mg56,00€1mL*10mM (DMSO)90,00€5mg93,00€10mg152,00€25mg259,00€50mg409,00€100mg592,00€Anisindione
CAS:Anisindione, a synthetic indanedione, inhibits vitamin K, blocking factors II, VII, IX, X, and proteins C, S.Fórmula:C16H12O3Pureza:98.25%Cor e Forma:Pale Yellow Crystals From Acetic Acid Or Ethanol SolidPeso molecular:252.26Flanvotumab
CAS:Flanvotumab (IMC-20D7S) is a humanized antibody targeting TYRP1 with strong antitumor effects via NK cells and ADCC.Pureza:> 95%Cor e Forma:LiquidPeso molecular:145.42 kDa(Rac)-Telmesteine
CAS:(Rac)-Telmesteine (3,4-Thiazolidinedicarboxylic Acid 3-Ethyl Ester) is an inhibitor of protease and is thus a suitable enzyme stabilizer.Fórmula:C7H11NO4SPureza:99.91%Cor e Forma:SolidPeso molecular:205.233-Isoquinolinecarboxamide, N-(1,1-dimethylethyl)decahydro-2-[(2R,3R)-2-hydroxy-3-[(3-hydroxy-2-methylbenzoyl)amino]-4-(phenylthio)butyl]-, (3S,4aS,8aS)-, methanesulfonate (1:1)
CAS:Fórmula:C33H49N3O7S2Pureza:96%Cor e Forma:SolidPeso molecular:663.8881Ellipyrone B
Ellipyrone B, a γ-pyrone-based macrocyclic polyketide with antihyperglycemic properties, demonstrates inhibitory activity against dipeptidyl peptidase-4 (IC 50Fórmula:C25H38O7Cor e Forma:SolidPeso molecular:450.575-epi-Arvestonate A
CAS:5-epi-Arvestonate A, a sesquiterpenoid from Seriphidium transiliense, stimulates melanogenesis and suppresses IFN-γ-chemokine in HaCaT cells.Fórmula:C16H26O5Cor e Forma:SolidPeso molecular:298.37VD2173
CAS:VD2173: a macrocyclic peptide that inhibits HGF serine proteases, matriptase, and hepsin, potentially for lung cancer research.Fórmula:C31H45N9O6SCor e Forma:SolidPeso molecular:671.81Ecallantide TFA
Ecallantide (DX-88) TFA, a specific recombinant plasma kallikrein inhibitor, directly inhibits bradykinin production and is indicated for the prevention ofCor e Forma:Odour SolidPseudostellarin G
CAS:Pseudostellarin G, a naturally occurring cyclo-octapeptide, exhibits inhibitory activity against tyrosinase and suppresses melanin production.Fórmula:C42H56N8O9Cor e Forma:SolidPeso molecular:816.94PROTAC CG167
PROTAC CG167 is a potent and selective PROTAC degrader of CypA. It degrades CypA in a dose-dependent manner in Jurkat cells, with a DC50 of 123 nM. Additionally, PROTAC CG167 exhibits antiviral activity by inhibiting HIV-1 and HCV. (Pink: CypA Ligand; Black: Linker; Blue: E3LigaseLigand)Fórmula:C65H79N13O11SCor e Forma:SolidPeso molecular:1250.47NIM811
CAS:NIM811 is an orally bioavailable dual inhibitor of mitochondrial permeability transition and cyclophilin.Fórmula:C62H111N11O12Pureza:98%Cor e Forma:SolidPeso molecular:1202.635Histatin 5 (TFA)(115966-68-2,free)
Histatin 5 (TFA)(115966-68-2,free) (Histatin 5 (TFA)) inhibits the activity of the host matrix metalloproteinases MMP-2 and MMP-9 with IC50s of 0.57 and 0.25 μMFórmula:C135H196F3N51O35Pureza:98%Cor e Forma:SolidPeso molecular:3150.32Stevia Powder
Stevia Powder, a natural sweetener, possesses antioxidant properties. It regulates antifibrotic pathways in cirrhotic rats, demonstrated by a reduction in hepatic stellate cells and decreased expression of matrix metalloproteinases MMP2 and MMP13. Furthermore, it increases the antifibrotic molecule Smad7, which helps prevent the elevation of serum necrosis and bile retention markers, thereby inhibiting the progression of liver fibrosis.Cor e Forma:Odour SolidL-Methionine-DL-sulfoximine
CAS:MSO blocks glutamine synthetase, impacts astroglia, and is used in convulsant research.Fórmula:C5H12N2O3SPureza:99.56% - ≥98%Cor e Forma:White Crystalline PowderPeso molecular:180.23Tyrosinase-IN-34
Tyrosinase-IN-34 (compound 5a), a human tyrosinase inhibitor (IC 50: 3.5 μM), shows promise in regulating melanogenesis and pigmentation.Fórmula:C19H14BrClN4OCor e Forma:SolidPeso molecular:429.7STK33-IN-1
CAS:STK33-IN-1 (compound 1) is a STK33 inhibitor, with an IC 50 of 7 nM.Fórmula:C24H27N7O2Cor e Forma:SolidPeso molecular:445.527Sofosbuvir impurity H
Sofosbuvir impurity H, an diastereoisomer of Sofosbuvir, is the impurity of Sofosbuvir.Fórmula:C29H33FN3O10PPureza:98%Cor e Forma:SolidPeso molecular:633.56Talabostat
CAS:Talabostat (PT100, Val-boroPro) is a potent, nonselective and orally available dipeptidyl peptidase IV (DPP-IV) inhibitor with a Ki of 0.18 nM.Fórmula:C9H19BN2O3Cor e Forma:SolidPeso molecular:214.07Ellipyrone A
Ellipyrone A: γ-pyrone macrocycle, inhibits DPP-4 (IC50=0.35mM), α-glucosidase (IC50=0.74mM), α-amylase (IC50=0.59mM).Fórmula:C25H34O8Cor e Forma:SolidPeso molecular:462.53Grazoprevir potassium salt
CAS:Grazoprevir, a drug for hepatitis C, is a second-gen NS3/4a protease inhibitor.
Fórmula:C38H49KN6O9SCor e Forma:SolidPeso molecular:805Nitidanin
Nitidanin is a useful organic compound for research related to life sciences and the catalog number is T125599.Fórmula:C21H24O8Cor e Forma:SolidPeso molecular:404.4156,6′-Dihydroxythiobinupharidine
CAS:6,6′-Dihydroxythiobinupharidine, a cysteine proteases inhibitor, amplifies DNA cleavage facilitated by human topoisomerase IIα and IIβ by approximately 8-foldFórmula:C30H42N2O4SCor e Forma:SolidPeso molecular:526.73PSI-353661
CAS:PSI-353661 (GS-558093), inhibits HCV's NS5B polymerase; EC90: 8nM (wild-type), 11nM (S282T); active in human hepatocytes.Fórmula:C24H32FN6O8PCor e Forma:SolidPeso molecular:582.52RJS308
RJS308 is a PROTAC degrader of cyclosporin A (cyclosporin A) with a DC50 of 284 nM. It exhibits antiviral activity by inhibiting the replication of HIV-1 and HCV. (Pink: ligand for target protein CypA ligand-2; Black: linker; Blue: ligand for E3 ligase VHL (S,R,S)-AHPC-Me)Fórmula:C63H75N13O11SCor e Forma:SolidPeso molecular:1222.42Ac-PAL-AMC
CAS:Ac-PAL-AMC is a β1i/LMP2-specific substrate that fluoresces when cleaved; useful for measuring immunoproteasome activity.Fórmula:C26H34N4O6Cor e Forma:SolidPeso molecular:498.57GSK2818713
CAS:GSK2818713 is a novel Hepatitis C NS5A replication complex inhibitor.Fórmula:C46H56N8O8Cor e Forma:SolidPeso molecular:849.002
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