Proteases/Proteassoma
Os inibidores de proteases e proteassomas são compostos que bloqueiam a atividade das proteases e do proteassoma, que estão envolvidos na degradação e renovação de proteínas. Esses inibidores são vitais para estudar a regulação da homeostase de proteínas, controle do ciclo celular e apoptose. Inibidores de proteases e proteassomas também são utilizados no tratamento de doenças como o câncer, onde a degradação anormal de proteínas desempenha um papel na progressão da doença. Ao inibir proteases ou o proteassoma, esses compostos podem induzir a morte celular em células cancerígenas e são ferramentas essenciais tanto na pesquisa básica quanto no desenvolvimento terapêutico. Na CymitQuimica, oferecemos uma ampla gama de inibidores de proteases e proteassomas de alta qualidade para apoiar sua pesquisa em bioquímica, biologia celular e desenvolvimento de medicamentos.
Subcategorias de "Proteases/Proteassoma"
- Acetil- CoA Carboxilase(34 produtos)
- Cisteína Protease(96 produtos)
- DPP-4(20 produtos)
- Glutaminase(40 produtos)
- HIV Protease(449 produtos)
- PAI-1(25 produtos)
- Inibidores de Protease(50 produtos)
- Receptor activado por protease(53 produtos)
- Proteassoma(94 produtos)
- Protease serina(50 produtos)
- p97(14 produtos)
Exibir 3 mais subcategorias
Foram encontrados 1044 produtos de "Proteases/Proteassoma"
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Sucunamostat
CAS:<p>Sucunamostat is an L-aspartic acid enteropeptidase inhibitor.</p>Fórmula:C22H22N4O8Cor e Forma:SolidPeso molecular:470.438LM11
<p>LM11 is a transglutaminase 2 (TG2) inhibitor that exhibits activity against glioblastoma cells by maintaining TG2 in a cytotoxic conformational state.</p>Fórmula:C26H18Cl2N4O5Peso molecular:536.06543KKI-5
CAS:<p>KKI 5: Serine protease inhibitor, blocks kallikrein & plasmin, potential for cancer therapy & angioedema treatment.</p>Fórmula:C35H55N11O9Pureza:98%Cor e Forma:SolidPeso molecular:773.88Fibrinopeptide B, human
CAS:<p>Fibrinopeptide B (FPB) is produced during the cleavage of fibrinogen, by thrombin, to fibrin monomer.</p>Fórmula:C66H93N19O25Pureza:98%Cor e Forma:SolidPeso molecular:1552.56CRA-2059
CAS:<p>CRA-2059 is a potent and selective inhibitor of tryptase, particularly targeting recombinant human tryptase-β (rHTβ), with a K i of 620 pM.</p>Fórmula:C34H46N12O8Pureza:97.68%Cor e Forma:SolidPeso molecular:750.818ZG36
<p>ZG36, a human Caseinolytic protease P (ClpP) agonist, non-selectively degrades respiratory chain complexes and reduces mitochondrial DNA, causing mitochondrial</p>Cor e Forma:Odour SolidPSI-7409
CAS:<p>PSI-7409 is the active 5'-triphosphate metabolite of Sofosbuvir (PSI-7977).</p>Fórmula:C10H16FN2O14P3Pureza:98%Cor e Forma:SolidPeso molecular:500.16Cys-TAT(47-57) acetate(583836-55-9 Free base)
<p>Cys-TAT(47-57) acetate is derived from the HIV-1 transactivating protein. Cys-TAT(47-57) acetate is an arginine rich peptide that can penetrate cells.</p>Fórmula:C69H128N34O16SPureza:95.1100%Cor e Forma:SolidPeso molecular:1722.04Sofosbuvir impurity H
<p>Sofosbuvir impurity H, an diastereoisomer of Sofosbuvir, is the impurity of Sofosbuvir.</p>Fórmula:C29H33FN3O10PPureza:98%Cor e Forma:SolidPeso molecular:633.56MK-6169
CAS:<p>MK-6169 is an effective Pan-Genotype Hepatitis C Virus NS5A inhibitor. It also has Optimized Activity against Common Resistance-Associated Substitutions.</p>Fórmula:C54H62FN9O8SPureza:98%Cor e Forma:SolidPeso molecular:1016.27-Methoxy obtusifolin
CAS:<p>7-Methoxy obtusifolin (Compound 4) is a chemical compound that acts as a competitive inhibitor of the enzyme tyrosinase, displaying an inhibitory concentration</p>Fórmula:C17H14O6Cor e Forma:SolidPeso molecular:314.29Ac-[Nle4,D-Phe7]-α-MSH (4-10)-NH2
CAS:Ac-[Nle4,D-Phe7]-α-MSH (4-10)-NH2, a melanotropin derivative and melanocyte-stimulating hormone, activates tyrosinase and demonstrates a thermoregulatory effectFórmula:C47H64N14O10Cor e Forma:SolidPeso molecular:985.1Recombinant Trypsin
<p>Recombinant Trypsin is a serine protease that hydrolyzes proteins at the carboxyl side of lysine or arginine.</p>JC-10
CAS:<p>JC-10 is a potent inhibitor of metalloproteinases and is often used as a probe.</p>Fórmula:C25H29Cl2IN4Pureza:95%Cor e Forma:SolidPeso molecular:583.34Emtricitabine S-oxide
CAS:<p>Emtricitabine treats HIV; its degradation byproduct is Emtricitabine S-oxide.</p>Fórmula:C8H10FN3O4SPureza:98%Cor e Forma:SolidPeso molecular:263.25AE-3763
CAS:<p>AE-3763 is a peptide-based human neutrophil elastase inhibitor (IC50: 29 nM).</p>Fórmula:C23H34F3N5O7Pureza:98%Cor e Forma:SolidPeso molecular:549.54Sadopeptins B
<p>Sadopeptins B, a natural product isolated from Streptomyces sp., is a potent proteasome inhibitor [1].</p>Fórmula:C48H69N9O13SCor e Forma:SolidPeso molecular:1012.18L-Methionine-DL-sulfoximine
CAS:<p>MSO blocks glutamine synthetase, impacts astroglia, and is used in convulsant research.</p>Fórmula:C5H12N2O3SPureza:99.56% - ≥98%Cor e Forma:White Crystalline PowderPeso molecular:180.23Relacatib
CAS:<p>Relacatib (SB-462795) is a potent cathepsins K, L, V inhibitor with high affinity (Ki: 41-68 pM) and reduces bone resorption effectively.</p>Fórmula:C27H32N4O6SCor e Forma:SolidPeso molecular:540.64Nostosin G
<p>Nostosin G, a linear peptide with Hpla, Hty, and argininal, inhibits trypsin effectively (IC50 = 0.1 μM).</p>Fórmula:C25H33N5O6Cor e Forma:SolidPeso molecular:499.56Sofosbuvir impurity A
CAS:<p>Sofosbuvir impurity A is an diastereoisomer of Sofosbuvir. Sofosbuvir is anHCV RNA replication inhibitor ,with potent anti-hepatitis C virus activity.</p>Fórmula:C22H29FN3O9PPureza:98%Cor e Forma:SolidPeso molecular:529.45CRA-2059 TFA
<p>CRA-2059 is a highly specific and selective tryptase inhibitor, with a Ki of 620 pM for recombinant human tryptase-β (rHTβ)[1][2].</p>Cor e Forma:SolidIchorcumab
CAS:<p>Ichorcumab (JNJ-375) is a fully human IgG4 antibody that targets thrombin. It binds to exosite 1 of thrombin, inhibiting substrate binding without affecting its catalytic activity. For isotype control, refer to HumanIgG1kappa, Isotype Control.</p>Cor e Forma:LiquidHCV-IN-7 hydrochloride
CAS:<p>HCV-IN-7 hydrochloride: Oral, potent HCV NS5A inhibitor, pan-genotypic, IC50s 3-47 pM, good pharmacokinetics, favorable liver uptake.</p>Fórmula:C40H50Cl2N8O6SPureza:98%Cor e Forma:SolidPeso molecular:841.85Rivulariapeptolides 1121
<p>Rivulariapeptolides 1121 inhibits serine proteases: chymotrypsin (IC50=35.52 nM), elastase (13.24 nM), proteinase K (48.05 nM).</p>Fórmula:C56H83N9O15Cor e Forma:SolidPeso molecular:1122.31TAPI1 acetate
<p>TAPI1 acetate (TNF-α processing inhibitor-1) is a TACE (ADAM17) inhibitor that inhibits shedding of TNF-α cytokine receptors; MMP inhibitor .</p>Fórmula:C28H41N5O7Pureza:98.82% - 99.94%Cor e Forma:SolidPeso molecular:559.65Sofosbuvir impurity N
CAS:<p>Sofosbuvir impurity N is an diastereoisomer of Sofosbuvir.Sofosbuvir is an HCV RNA replication inhibitor, with potent anti-hepatitis C virus activity.</p>Fórmula:C20H25FN3O9PPureza:98%Cor e Forma:SolidPeso molecular:501.404TMC647055 Choline salt
<p>TMC647055 choline salt is a selective and cell-permeating inhibitor of HCV NS5B (IC50: 34 nM).</p>Fórmula:C37H53N5O8SPureza:98%Cor e Forma:SolidPeso molecular:727.91Cathepsin C-IN-6
<p>Cathepsin C-IN-6 (compound 2), an E-64c-hydrazideas-derived inhibitor of cathepsin C, possesses anti-inflammatory properties and impedes neutrophil elastase</p>Fórmula:C24H35N5O4·xC2HF3O2Cor e Forma:SolidTWH106
<p>TWH106 is an inhibitor of the cyclophilin (Cyp) enzyme, exhibiting strong affinity for CypA and CypB with dissociation constants (KD) of 53 nM and 139 nM, respectively. It effectively inhibits the replication of HIV and HCV, demonstrating antiviral activity.</p>Cor e Forma:Odour SolidRJS308
<p>RJS308 is a PROTAC degrader of cyclosporin A (cyclosporin A) with a DC50 of 284 nM. It exhibits antiviral activity by inhibiting the replication of HIV-1 and HCV. (Pink: ligand for target protein CypA ligand-2; Black: linker; Blue: ligand for E3 ligase VHL (S,R,S)-AHPC-Me)</p>Fórmula:C63H75N13O11SCor e Forma:SolidPeso molecular:1222.42PSI-353661
CAS:<p>PSI-353661 (GS-558093), inhibits HCV's NS5B polymerase; EC90: 8nM (wild-type), 11nM (S282T); active in human hepatocytes.</p>Fórmula:C24H32FN6O8PCor e Forma:SolidPeso molecular:582.52Hepcidin-1 (mouse)
CAS:<p>Hepcidin-1 (mouse) is a peptide hormone that regulates iron balance, elevates mRNA for TRAP, cathepsin K, and MMP-9, and promotes TRAP-5b protein secretion.</p>Fórmula:C111H169N31O35S8Cor e Forma:SolidPeso molecular:2754.24Procizumab
<p>Procizumab is a humanized IgG1 antibody that targets dipeptidyl peptidase 3 (DPP3). It shows potential for investigating sepsis. For the isotype control, refer to HumanIgG1kappa, Isotype Control.</p>Cor e Forma:Odour LiquidHistatin 5
CAS:<p>Histatin 5, a human saliva peptide, blocks MMP-2 and MMP-9 at IC50s of 0.57/0.25 μM and kills fungi.</p>Fórmula:C133H195N51O33Pureza:98%Cor e Forma:SolidPeso molecular:3036.29Alisporivir
CAS:<p>Alisporivir (Debio-025) is a cyclophilin A inhibitor that disrupts the interaction between CypA and NS5A. HCV activity in vivo and in vitro.</p>Fórmula:C63H113N11O12Pureza:99.95%Cor e Forma:SolidPeso molecular:1216.64Thrombin (MW 37kDa)
CAS:<p>Thrombin (MW 37kDa) is a trypsin-like allosteric serine protease.</p>Pureza:98%Cor e Forma:SolidPeso molecular:37kDaEllipyrone B
<p>Ellipyrone B, a γ-pyrone-based macrocyclic polyketide with antihyperglycemic properties, demonstrates inhibitory activity against dipeptidyl peptidase-4 (IC 50</p>Fórmula:C25H38O7Cor e Forma:SolidPeso molecular:450.57Dutogliptin tartrate
CAS:<p>Dutogliptin tartrate is an effective and selective oral dipeptide-peptide-4 (DPP4) inhibitor for the treatment of type 2 diabetes mellitus.</p>Fórmula:C14H26BN3O9Pureza:98%Cor e Forma:SolidPeso molecular:391.18Tyrosinase-IN-36
<p>Tyrosinase-IN-36 is a moderately potent inhibitor of tyrosine, exhibiting an inhibition percentage of 42.75% compared to kojic acid at a concentration of 100 μM and possesses antioxidant activity.</p>Cor e Forma:Odour SolidPS 915
CAS:<p>PS 915 is a substrate for colorimetric assay. It was used for plasma antithrombin.</p>Fórmula:C27H36ClN7O6Pureza:98%Cor e Forma:SolidPeso molecular:590.08α 1 Antichymotrypsin, Human Plasma
CAS:<p>Alpha 1 Antichymotrypsin, Human Plasma is an inhibitor of serine proteases. This compound is present in amyloid lesions associated with Alzheimer's disease and can be utilized in Alzheimer's research.</p>Cor e Forma:SolidBefovacimab
CAS:<p>Befovacimab, a human IgG2 antibody, targets TFPI for hemophilia A/B research.</p>Cor e Forma:LiquidPF 00356231
CAS:<p>PF 00356231 is a selectivity inhibitor MMP-12 and can be used in studies about the treatment of emphysema and chronic obstructive pulmonary disease (COPD).</p>Fórmula:C25H20N2O3SPureza:99.35%Cor e Forma:SolidPeso molecular:428.5TR-107
CAS:<p>TR-107 (Anticancer agent 230) is a mitochondrial protease ClpP activator that inhibits tumor growth in the MDA-MB-231 xenograft model.</p>Fórmula:C22H19ClN4OCor e Forma:SoildPeso molecular:390.87EP 171
CAS:<p>EP 171 is a potent agonist of TP-receptors.</p>Fórmula:C23H29FO5Cor e Forma:SolidPeso molecular:404.47Leptosphaerodione
CAS:<p>Leptosphaerodione from Remotididymella sp.: a potent UPS inhibitor with 3.2 μM IC50 in HeLa cells; anti-tumor.</p>Fórmula:C21H22O5Cor e Forma:SolidPeso molecular:354.4Histatin 5 TFA
Histatin 5 TFA effectively inhibits host matrix metalloproteinases (MMP-2) and (MMP-9), demonstrating inhibition concentrations (IC 50s) of 0.57 μM and 0.25 μMFórmula:C135H196N51F3O35Cor e Forma:SolidPeso molecular:3150.31HIV-1 inhibitor-6
CAS:<p>HIV-1 inhibitor-6 (3-Pyridinecarboxamide, 1,4-dihydro-1-methyl-N-(5-nitro-1,2-benzisothiazol-3-yl)-4-oxo-) is a potent HIV-1 pre-mRNA selective splicing</p>Fórmula:C14H10N4O4SPureza:99.33%Cor e Forma:SolidPeso molecular:330.32(Iso)-Fosdevirine
CAS:<p>(Iso)-Fosdevirine ( (Iso)-GSK2248761), a reverse transcriptase (NNRTI) inhibitor with anti-HIV activity, is used in the study of neurological diseases.</p>Fórmula:C20H17ClN3O3PPureza:99.93%Cor e Forma:SoildPeso molecular:413.79Ala-Phe-Pro-pNA TFA
<p>Ala-Phe-Pro-pNA TFA serves as a chromogenic substrate for tripeptidyl peptidase and can be utilized to assess the enzyme's activity.</p>Cor e Forma:Odour SolidSofosbuvir impurity M
CAS:<p>Sofosbuvir impurity M is an diastereoisomer of Sofosbuvir.Sofosbuvir is an HCV RNA replication inhibitor, with potent anti-hepatitis C virus activity.</p>Fórmula:C22H30N3O10PPureza:98%Cor e Forma:SolidPeso molecular:527.467BPHA
CAS:<p>BPHA is a selective oral inhibitor of MMP-2/9/14 (IC50: 12/16/17 nM), not affecting MMP-1/3/7, with anti-angiogenic and anti-tumor properties.</p>Fórmula:C21H20N2O4SPureza:99.44%Cor e Forma:SolidPeso molecular:396.46Obtusifolin-2-O-glucoside
CAS:<p>Obtusifolin-2-O-glucoside (compound 7), a tyrosinase inhibitor with an IC50 value of 9.2 μM, can be isolated from cassia seed [1].</p>Fórmula:C22H22O10Cor e Forma:SolidPeso molecular:446.4APC-6860
CAS:<p>APC-6860, a serine protease inhibitor, targets multiple enzymes; most potent against human urokinase (Ki: 0.1 µM). Used in cancer research.</p>Fórmula:C9H7IN2SCor e Forma:SolidPeso molecular:302.13Z-Leu-Tyr-Chloromethylketone
CAS:<p>Z-Leu-Tyr-Chloromethylketone is a calpain inhibitor [1].</p>Fórmula:C24H29ClN2O5Cor e Forma:SolidPeso molecular:460.95NS5A-IN-4
CAS:<p>NS5A-IN-4 (Compound 1.12) is a hepatitis C inhibitor effective against multiple genotypes, with IC50 values ranging from 1.2 to 2296 pM.</p>Fórmula:C47H48N8O6Cor e Forma:SolidPeso molecular:820.93HIV-1 Rev (34-50)
CAS:<p>HIV-1 Rev (34-50) (HIV-1 rev Protein (34-50)) is a 17 amino acid peptide with anti-HIV-1 activity.</p>Fórmula:C97H173N51O24Pureza:99.91%Cor e Forma:SolidPeso molecular:2437.74Talabostat
CAS:<p>Talabostat (PT100, Val-boroPro) is a potent, nonselective and orally available dipeptidyl peptidase IV (DPP-IV) inhibitor with a Ki of 0.18 nM.</p>Fórmula:C9H19BN2O3Cor e Forma:SolidPeso molecular:214.07Nitidanin
<p>Nitidanin is a useful organic compound for research related to life sciences and the catalog number is T125599.</p>Fórmula:C21H24O8Cor e Forma:SolidPeso molecular:404.415Tyrosinase/elastase-IN-1
<p>Tyrosinase/elastase-IN-1, a triterpenoid extracted from the leaves of Rubus fraxinifolius, exhibits inhibitory activities against both tyrosinase and elastase</p>Fórmula:C33H52O5Cor e Forma:SolidPeso molecular:528.76Clathrin-IN-1
CAS:<p>Pitstop 2 inhibits clathrin-mediated endocytosis, targeting clathrin's terminal domain, with potential in cancer research.</p>Fórmula:C20H13BrN2O3S2Pureza:99.53%Cor e Forma:SolidPeso molecular:473.36GSK2336805
CAS:<p>GSK-2336805, an HCV NS5A inhibitor, is effective against genotypes 1, 4, 5, and some of 6.</p>Fórmula:C42H52N8O8Cor e Forma:SolidPeso molecular:796.91CL 82198 hydrochloride
CAS:<p>CL 82198 hydrochloride selectively inhibits MMP-13, not MMP-1/9/TACE, and blocks HP75 invasion and neurotoxicity in zebrafish.</p>Fórmula:C17H23ClN2O3Cor e Forma:SolidPeso molecular:338.83Dansyl-Glu-Gly-Arg-Chloromethylketone
CAS:Dansyl-Glu-Gly-Arg-Chloromethylketone is a protease inhibitor that specifically impedes serine/threonine proteases and has been shown to inhibit activatedFórmula:C26H36ClN7O7SCor e Forma:SolidPeso molecular:626.12VPLSLYSG
CAS:<p>VPLSLYSG, an octapeptide, degraded by MMP-9, MMP-1, MMP-2; potential MMP substrate uses.</p>Fórmula:C39H62N8O12Cor e Forma:SolidPeso molecular:834.96Recombinant Proteinase K
<p>Recombinant Proteinase K: serine protease, cleaves carboxy-terminus peptides, digests proteins, purifies nucleic acids.</p>Cor e Forma:SolidZ-Arg-Arg-βNA acetate
CAS:<p>Z-Arg-Arg-βNA acetate serves as a sensitive dipeptide substrate for Cathepsin B protease, while demonstrating resistance to proteases H and L. This compound is crucial for differentiating non-Cathepsin B type proteins.</p>Fórmula:C32H43N9O6Cor e Forma:SolidPeso molecular:649.74MMP-3 Inhibitor acetate
<p>MMP-3 Inhibitor acetate is a cell-permeable and potent inhibitor of human MMP-3.</p>Fórmula:C29H50N10O11SPureza:98%Cor e Forma:SolidPeso molecular:746.83Peptide 74
CAS:<p>Peptide 74 is a synthetic peptide. It also inhibits the activated form of this enzyme.</p>Fórmula:C62H107N23O20S2Pureza:98%Cor e Forma:SolidPeso molecular:1558.79Sitagliptin fenilalanil hydrochloride
CAS:<p>Sitagliptin phenylalanine hydrochloride, a dipeptidyl peptidase-4 (DPP-4) inhibitor [1], is a chemical compound utilized in medical applications.</p>Fórmula:C25H25ClF6N6O2Cor e Forma:SolidPeso molecular:590.95PROTAC 20S proteasome subunit β5 degrader 2
<p>PROTAC 20S proteasome subunit β5 degrader 2 is a PROTAC degrader targeting the 20S proteasome subunit β5 (20Sproteasomesubunit β5), with a DC50 of 0.16 μM. It inhibits the proliferation of FaDu cancer cells, showcasing an IC50 of 0.23 μM. Additionally, PROTAC20Sproteasomesubunit β5 degrader 2 demonstrates antitumor activity in a mouse model.</p>Cor e Forma:Odour SolidAMG-222
CAS:<p>AMG-222 (ALS-2-0426, ALS-20426) is a DPP-4 inhibitor and may be used in the treatment of type 2 diabetes.</p>Fórmula:C32H39N9O3Cor e Forma:SolidPeso molecular:597.71PPACK II
CAS:<p>PPACK II is an irreversible and specific glandular and plasma kallikreins inhibitor [1] .</p>Fórmula:C25H33ClN6O3Cor e Forma:SolidPeso molecular:501.02MMP-3 Inhibitor
CAS:<p>MMP-3 Inhibitor is a peptide matrix metalloproteinase-3 (MMP-3) inhibitor with a Ki value of 95 nM.MMP-3 inhibitor has anticancer and antitumor activity.</p>Fórmula:C27H46N10O9SPureza:98.87%Cor e Forma:SolidPeso molecular:686.78HCV-IN-4
CAS:<p>HCV-IN-4: Potent, oral HCV NS5A inhibitor; effective vs GT1a/b, GT2b, GT3a, Y93H, L31V; EC90s: 3 pM-0.02 nM.</p>Fórmula:C52H58FN9O8Pureza:98%Cor e Forma:SolidPeso molecular:956.07Leptosin D
CAS:<p>Leptosin D, a thiodiketopiperazine alkaloid derived from mushrooms, effectively inhibits tyrosinase activity, demonstrating an inhibition concentration (IC50)</p>Fórmula:C25H24N4O3S2Cor e Forma:SolidPeso molecular:492.61HIV-1 protease-IN-14
<p>HIV-1protease-IN-14 (compound 5ae) is an effective inhibitor of HIV-1protease, exhibiting Ki values of 0.28 nM and 56.9 nM against WTHIV-1PR and R41THIV-1PR, respectively. This compound also demonstrates low cytotoxicity.</p>Cor e Forma:Odour SolidIso-VQA-ACC acetate
<p>Iso-VQA-ACC acetate serves as a substrate for the constitutive proteasome.</p>Cor e Forma:Odour SolidHCV-IN-41
CAS:<p>HCV-IN-41: potent HCV inhibitor; EC50 - 0.006762 nM (1b), 5.183 nM (2a), 1.365 nM (3a), 142.2 nM (4a); hinders RNA replication.</p>Fórmula:C48H56N6O8Cor e Forma:SolidPeso molecular:844.99MMP-9/MMP-13 Inhibitor I
CAS:<p>MMP-9/MMP-13 Inhibitor I is a dual inhibitor of MMP-9 and MMP-13 with IC50 of both 0.9 nM.</p>Fórmula:C25H25N3O6SCor e Forma:SolidPeso molecular:495.5515,16-Dihydrotanshindiol C
<p>15,16-Dihydrotanshindiol C is a useful organic compound for research related to life sciences and the catalog number is T123985.</p>Fórmula:C18H18O5Cor e Forma:SolidPeso molecular:314.337Grazoprevir potassium salt
CAS:<p>Grazoprevir, a drug for hepatitis C, is a second-gen NS3/4a protease inhibitor.</p>Fórmula:C38H49KN6O9SCor e Forma:SolidPeso molecular:805RXP470
CAS:<p>RXP470 is a potent and selective MMP-12 inhibitor (Ki 0.24 nM).</p>Fórmula:C35H35BrClN4O10PCor e Forma:SolidPeso molecular:8186,6′-Dihydroxythiobinupharidine
CAS:<p>6,6′-Dihydroxythiobinupharidine, a cysteine proteases inhibitor, amplifies DNA cleavage facilitated by human topoisomerase IIα and IIβ by approximately 8-fold</p>Fórmula:C30H42N2O4SCor e Forma:SolidPeso molecular:526.73Ac-PAL-AMC
CAS:<p>Ac-PAL-AMC is a β1i/LMP2-specific substrate that fluoresces when cleaved; useful for measuring immunoproteasome activity.</p>Fórmula:C26H34N4O6Cor e Forma:SolidPeso molecular:498.57LXE408 fumarate
<p>LXE408 fumarate: orally available, selective kinetoplastid proteasome inhibitor with IC50/EC50 of 0.04 μM for L. donovani; potentially aids in VL research.</p>Fórmula:C27H22FN7O6Pureza:99.89%Cor e Forma:SoildPeso molecular:559.51Tyrosinase-IN-38
<p>Tyrosinase-IN-38 (compound 6b) is a competitive inhibitor of tyrosinase, demonstrating an IC50 of 25.82 μM and exhibits antioxidant activity.</p>Cor e Forma:Odour SolidPROTAC CG167
<p>PROTAC CG167 is a potent and selective PROTAC degrader of CypA. It degrades CypA in a dose-dependent manner in Jurkat cells, with a DC50 of 123 nM. Additionally, PROTAC CG167 exhibits antiviral activity by inhibiting HIV-1 and HCV. (Pink: CypA Ligand; Black: Linker; Blue: E3LigaseLigand)</p>Fórmula:C65H79N13O11SCor e Forma:SolidPeso molecular:1250.47FFAGLDD TFA
<p>FFAGLDD TFA: MMP9 peptide for controlled DOX delivery to cytoplasm.</p>Fórmula:C39H50F3N7O14Pureza:98%Cor e Forma:SolidPeso molecular:897.855-epi-Arvestonate A
CAS:<p>5-epi-Arvestonate A, a sesquiterpenoid from Seriphidium transiliense, stimulates melanogenesis and suppresses IFN-γ-chemokine in HaCaT cells.</p>Fórmula:C16H26O5Cor e Forma:SolidPeso molecular:298.37VD2173
CAS:<p>VD2173: a macrocyclic peptide that inhibits HGF serine proteases, matriptase, and hepsin, potentially for lung cancer research.</p>Fórmula:C31H45N9O6SCor e Forma:SolidPeso molecular:671.81Bortezomib analog
<p>Bortezomibanalog (Compound 13) is an analog of Bortezomib, functioning as an active control ligand for the 20S proteasome subunit β5.</p>Cor e Forma:Odour SolidNIM811
CAS:<p>NIM811 is an orally bioavailable dual inhibitor of mitochondrial permeability transition and cyclophilin.</p>Fórmula:C62H111N11O12Pureza:98%Cor e Forma:SolidPeso molecular:1202.635SFTI-1
CAS:SFTI-1, a cyclic peptide trypsin inhibitor comprising 14 amino acid residues, is a potent Bowman-Birk inhibitor.Fórmula:C67H104N18O18S2Cor e Forma:SolidPeso molecular:1513.78Rivulariapeptolides 1155
<p>Rivulariapeptolides 1155 inhibits chymotrypsin (41.84 nM), elastase (4.94 nM), and proteinase K (56.54 nM).</p>Fórmula:C59H81N9O15Cor e Forma:SolidPeso molecular:1156.33CP-346086 dihydrate
CAS:<p>CP-346086 dihydrate is a strong oral MTP inhibitor with 2.0 nM IC50, reducing cholesterol and triglycerides in vivo.</p>Fórmula:C26H26F3N5O3Cor e Forma:SolidPeso molecular:513.521Cathepsin L-IN-3
CAS:<p>Cathepsin L-IN-3, a tripeptide-sized inhibitor of cathepsin L, effectively targets this specific enzyme.</p>Fórmula:C41H49N7O4SCor e Forma:SolidPeso molecular:735.94Pentosan Polysulfate
CAS:<p>Pentosan Polysulfate: anti-HIV, anti-inflammatory, supports cartilage, treats interstitial cystitis.</p>Pureza:98%Cor e Forma:SolidPeso molecular:N/AAnticancer agent 114
<p>Anticancer agent 114: oral dipeptide boronic acid, proteasome inhibitor, IC 50 = 2.2 nM, halts RPMI-8226 cell growth, for multiple myeloma research.</p>Fórmula:C28H33BF6N2O7Cor e Forma:SolidPeso molecular:634.37
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