Proteases/Proteassoma
Os inibidores de proteases e proteassomas são compostos que bloqueiam a atividade das proteases e do proteassoma, que estão envolvidos na degradação e renovação de proteínas. Esses inibidores são vitais para estudar a regulação da homeostase de proteínas, controle do ciclo celular e apoptose. Inibidores de proteases e proteassomas também são utilizados no tratamento de doenças como o câncer, onde a degradação anormal de proteínas desempenha um papel na progressão da doença. Ao inibir proteases ou o proteassoma, esses compostos podem induzir a morte celular em células cancerígenas e são ferramentas essenciais tanto na pesquisa básica quanto no desenvolvimento terapêutico. Na CymitQuimica, oferecemos uma ampla gama de inibidores de proteases e proteassomas de alta qualidade para apoiar sua pesquisa em bioquímica, biologia celular e desenvolvimento de medicamentos.
Subcategorias de "Proteases/Proteassoma"
- Acetil- CoA Carboxilase(38 produtos)
- Cisteína Protease(111 produtos)
- DPP-4(27 produtos)
- Glutaminase(46 produtos)
- HIV Protease(508 produtos)
- PAI-1(26 produtos)
- Inibidores de Protease(50 produtos)
- Receptor activado por protease(55 produtos)
- Proteassoma(86 produtos)
- Protease serina(54 produtos)
- p97(15 produtos)
Exibir 3 mais subcategorias
Foram encontrados 981 produtos de "Proteases/Proteassoma"
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LU-002i
CAS:LU-002i is a selective inhibitor targeting the human proteasome subunits β2c and β2i, demonstrating an inhibitory concentration (IC50) of 220 nM for β2i [1].Fórmula:C35H52N4O7Pureza:98%Cor e Forma:SolidPeso molecular:640.81BMS-538305 HCl
CAS:BMS-538305 is a potent, selective inhibitor of dipeptidyl peptidase IV (DPP-IV).Fórmula:C17H27ClN2O2Cor e Forma:SolidPeso molecular:326.86Cardanol diene
CAS:Cardanol diene: phenol in cashew shells; anti-tyrosinase (IC50=52.5μM); used to make anti-E. coli biofilm complexes.Fórmula:C21H32OCor e Forma:SolidPeso molecular:300.48PTC725
CAS:PTC725 is a selective HCV 1b replicons inhibitor. It has been shown to target the nonstructural protein 4B.Fórmula:C23H18F4N6O2SPureza:98%Cor e Forma:SolidPeso molecular:518.49Z-LVG
CAS:Z-LVG, an irreversible cysteine protease inhibitor and a tripeptide derivative of cystatin C, serves as an inhibitor of viral replication and is utilized inFórmula:C21H31N3O6Cor e Forma:SolidPeso molecular:421.49LONP1-IN-2
CAS:LONP1-IN-2: Potent LONP1 inhibitor, IC50=0.187μM; weak on 20S proteasome (>10μM); for cancer research.Fórmula:C16H27BN4O4Cor e Forma:SolidPeso molecular:350.22MK-3281
CAS:MK-3281: Oral, potent HCV NS5B inhibitor with promising properties and efficacy in replication trials, suitable for clinical use.Fórmula:C29H37N3O3Cor e Forma:SolidPeso molecular:475.62ASP-8497
CAS:ASP8497 is a potent DPP-IV inhibitor enhancing GLP-1, used for type 2 diabetes and glucose intolerance.Fórmula:C18H27FN4O7SCor e Forma:SolidPeso molecular:462.49Cipemastat
CAS:Cipemastat is a competitive inhibitor of human collagenases 1, 2, and 3 (Kis: 3.0, 4.4, and 3.4 nM).Fórmula:C22H36N4O5Pureza:98%Cor e Forma:SolidPeso molecular:436.55Proteasome-IN-5
CAS:Proteasome-IN-5, also known as compound 5, acts as a proteasome inhibitor [1].Fórmula:C20H30BN5O7Pureza:98%Cor e Forma:SolidPeso molecular:463.29MMP3 inhibitor 1
CAS:MMP3 inhibitor 1 is a potent and highly selective inhibitor of MMP-3 (IC50 of 1 nM).Fórmula:C23H31N3O6SPureza:98%Cor e Forma:SolidPeso molecular:477.57Collagen proline hydroxylase inhibitor
CAS:Collagen proline hydroxylase inhibitor is an inhibitor collagen proline hydroxylase and useful for antifibrotic proliferative agents.Fórmula:C18H18N4O4Pureza:98%Cor e Forma:SolidPeso molecular:354.36MMP-9-IN-8
CAS:MMP-9-IN-8 (Compound 3), an MMP-9 inhibitor, exhibits inhibitory activities of 42.16% at 10 μM and 58.28% at 50 μM.Fórmula:C20H21F4N7OCor e Forma:SolidPeso molecular:451.42LU-005i
CAS:LU-005i is a powerful inhibitor targeting the β5i subunit of immunoproteasomes, displaying a high potency with an IC 50 value of 6.6 nM, and exhibits selectivity by preferring β5i over the β5c subunit, which has an IC 50 value of 287 nM [1].Fórmula:C31H46N4O7Cor e Forma:SolidPeso molecular:586.72Proteasome β2c/i-IN-1
CAS:Proteasome β2c/i-IN-1 (compound 37) serves as a selective inhibitor targeting the β2c and β2i subunits of the human proteasome [1].Fórmula:C32H48N4O7Pureza:98%Cor e Forma:SolidPeso molecular:600.75LMP7-IN-2
CAS:LMP7-IN-2 is an inhibitor of LMP7 and may be utilized in the treatment of associated inflammatory diseases and disorders [1].Fórmula:C28H27N3O3SCor e Forma:SolidPeso molecular:485.6Z-PDLDA-NHOH
CAS:Z-PDLDA-NHOH is a potent, specific vertebrate collagenase inhibitor [1].Fórmula:C22H32N4O6Cor e Forma:SolidPeso molecular:448.51H-Gly-Pro-Hyp-OH acetate
CAS:H-Gly-Pro-Hyp-OH, a peptide dipeptidyl peptidase 4 (DPP-4) inhibitor with an inhibition concentration (IC50) of 2.51 mM, effectively hinders the activity of the DPP-4 enzyme.Fórmula:C12H19N3O5C2H4O2Cor e Forma:SolidPeso molecular:345.35GSK-2485852
CAS:GSK-2485852, a NS5B inhibitor, is used potentially for treatment of HCV infection.Fórmula:C27H25BF2N2O6SCor e Forma:SolidPeso molecular:554.37XL-784 free base
CAS:XL-784 free base selectively inhibits MMPs with IC50: MMP-1 (1.9µM), MMP-2 (0.81nM), MMP-3 (120nM), MMP-8 (10.8nM), MMP-9 (18nM), MMP-13 (0.56nM).Fórmula:C21H22ClF2N3O8SPureza:98%Cor e Forma:SolidPeso molecular:549.93MDL-101146, (R)-
CAS:MDL-101146, (R)- is an effective orally active inhibitor of human neutrophil elastase.Fórmula:C29H37F5N4O6Pureza:98%Cor e Forma:SolidPeso molecular:632.62SSR 69071
CAS:SSR69071: selective neutrophil elastase inhibitor, stronger for humans (Ki=0.0168 nM), may treat COPD, asthma, and reduce heart injury.Fórmula:C27H32N4O7SCor e Forma:SolidPeso molecular:556.63Phe-Pro-Ala-pNA
CAS:Phe-Pro-Ala-pNA is a chromogenic substrate utilized for assessing tripeptidyl peptidase activity.Fórmula:C23H27N5O5Cor e Forma:SolidPeso molecular:453.49MDL 27324
CAS:MDL 27324 is an inhibitor of human neutrophil elastase.Fórmula:C29H38F3N5O6SPureza:98%Cor e Forma:SolidPeso molecular:641.7NS5A-IN-3
CAS:NS5A-IN-3 is a potent NS5A inhibitor with high efficacy against HCV 1b, good activity on 3a, and strong metabolic stability; superior to daclatasvir.Fórmula:C44H44N6O8Pureza:98%Cor e Forma:SolidPeso molecular:784.86TP0556351
CAS:TP0556351: potent MMP2 inhibitor with 0.2 nM IC50, reduces collagen in pulmonary fibrosis mice.Fórmula:C50H70N10O16Pureza:98%Cor e Forma:SolidPeso molecular:1067.15BAY-678
CAS:BAY-678: Oral selective human neutrophil elastase inhibitor; IC50: 20 nM; SGC-approved chemical probe.Fórmula:C20H15F3N4O2Pureza:99.36%Cor e Forma:SolidPeso molecular:400.35Ref: TM-T10473
5mg37,00€1mL*10mM (DMSO)42,00€10mg60,00€25mg119,00€50mg173,00€100mg264,00€200mg374,00€Z-FG-NHO-BzOME
CAS:Z-FG-NHO-BzOME is a chemical compound functioning as a cysteine protease inhibitor, selectively targeting and inhibiting cathepsin B, cathepsin L, cathepsin S,Fórmula:C27H27N3O7Cor e Forma:SolidPeso molecular:505.52ABP 25
CAS:ABP 25 is a highly potent and selective activity-based probe (ABP) for cathepsin K imaging.Fórmula:C55H66ClN5O3Cor e Forma:SolidPeso molecular:880.6KB-R7785
CAS:KB-R7785 is a novel ADAM12/MMP inhibitor improving heart function and insulin sensitivity by blocking HB-EGF and TNF-alpha.Fórmula:C18H27N3O4Cor e Forma:SolidPeso molecular:349.42MDL 101146
CAS:MDL 101146 is an orally active neutrophil elastase inhibitor.Fórmula:C29H37F5N4O6Pureza:98%Cor e Forma:SolidPeso molecular:632.62Cathepsin Inhibitor 2
CAS:Cathepsin Inhibitor 2 is a potent Cathepsin S inhibitor (Ki: <20 nM).Fórmula:C19H21F6N3OPureza:98%Cor e Forma:SolidPeso molecular:421.38NCI-B16
CAS:NCI-B16 is a small-molecule RNA binder that inhibits HCV (hepatitis C virus) replication [1].Fórmula:C27H26N8O4Cor e Forma:SolidPeso molecular:526.55O-Benzoylhydroxylamine
CAS:O-Benzoyl hydroxylamine exhibits properties as a dipeptidyl peptidase-IV (DPP-IV) inhibitor and demonstrates antidiabetic effects[1].Fórmula:C7H7NO2Cor e Forma:SolidPeso molecular:137.14Neurodegenerative Disorder-Targeting Compound 1
CAS:Neurodegenerative Disorder-Targeting Compound 1 is an inhibitor of calpain [1].Fórmula:C28H28N4O4Pureza:98%Cor e Forma:SolidPeso molecular:484.55MMP-7-IN-2
CAS:MMP-7-IN-2 acts as a selective and potent MMP7 inhibitor and can be used to study inflammatory responses and vascular-related diseases.Fórmula:C28H40ClF3N6O9SPureza:97.82%Cor e Forma:SolidPeso molecular:729.17MMP13-IN-3
CAS:MMP13-IN-3 is an oral, selective MMP-13 inhibitor with IC50 of 1 nM, >1000x selective, for osteoarthritis treatment.Fórmula:C24H22N4O5Pureza:99.76%Cor e Forma:SolidPeso molecular:446.46Ref: TM-T16124
1mg93,00€5mg205,00€1mL*10mM (DMSO)227,00€10mg334,00€25mg587,00€50mg802,00€100mg1.108,00€MMP-145
CAS:MMP-145 is used as a protease inhibitor.Fórmula:C20H20N2O7SPureza:98%Cor e Forma:SolidPeso molecular:432.45BMS-189664
CAS:BMS-189664 is an inhibitor of thrombin.Fórmula:C22H34N6O4SPureza:98%Cor e Forma:SolidPeso molecular:478.61MMP-3 Inhibitor VIII
CAS:Matrix metalloproteinase-3 (MMP-3), also known as stromelysin-1, is a critical enzyme involved in tissue remodeling and repair through its role in degrading extracellular matrix proteins, facilitating cell migration. This enzyme has been implicated in various physiological processes including vascular remodeling associated with aneurysm formation, wound healing, the progression of atherosclerosis, and tumor initiation. MMP-3 inhibitor VIII, a cell-permeable sulfonamide-based hydroxamic acid, effectively inhibits MMP-3 by binding to its active site (Ki = 23 nM), thus blocking its enzymatic activity. Additionally, this inhibitor has been demonstrated to suppress the activity of mouse macrophage metalloelastase MME/MMP-12, with an IC50 value of 13 nM, highlighting its potential utility in research on tissue remodeling and disease processes involving MMPs.Fórmula:C20H26N2O5SCor e Forma:SolidPeso molecular:406.5GSK-625433
CAS:GSK-625433: Homochiral inhibitor blocks HCV genotypes 1a/1b polymerase.Fórmula:C26H32N4O5SCor e Forma:SolidPeso molecular:512.62NK3201
CAS:NK3201, a specific chymase inhibitor, suppresses bleomycin-induced pulmonary fibrosis in hamsters.Fórmula:C31H29N5O6Pureza:98%Cor e Forma:SolidPeso molecular:567.59Petesicatib
CAS:Petesicatib is an inhibitor of cathepsin S. Petesicatib used in the research of immune diseases.Fórmula:C25H23F6N5O4SPureza:99.76%Cor e Forma:SolidPeso molecular:603.54Ref: TM-T16474
1mg100,00€5mg236,00€1mL*10mM (DMSO)314,00€10mg371,00€25mg735,00€50mg1.134,00€100mg1.468,00€200mg1.972,00€FK706
CAS:FK706, a human neutrophil elastase inhibitor (IC50: 83 nM, Ki: 4.2 nM), also blocks mouse and porcine elastases. Anti-inflammatory.Fórmula:C26H33F3N4NaO7Cor e Forma:SolidPeso molecular:593.556XL-784
CAS:XL-784 is a selective MMP inhibitor with low IC50s for MMP-1,2,3,8,9,13, modulating extracellular matrix remodeling, tumor invasion, and metastasis in cancer.Fórmula:C42H42Cl2F4MgN6O16S2Pureza:98%Cor e Forma:SolidPeso molecular:1122.15ND-378
CAS:ND-378 is a potent and selective inhibitor of MMP-2 with no inhibition on MMP-9 and MMP-14.Fórmula:C18H19NO4S2Pureza:98%Cor e Forma:SolidPeso molecular:377.48AZD-7295
CAS:AZD-7295 (A-689) is an NS5A inhibitor that may be used to treat HCV infection.Fórmula:C32H35F3N4O5SCor e Forma:SolidPeso molecular:644.7ONO 4817
CAS:ONO-4817 suppresses MMPs, limiting plaque progression and aortic hyperplasia in hyperlipidemic rabbits.Fórmula:C22H28N2O6Cor e Forma:SolidPeso molecular:416.47DCLK1-IN-2
CAS:DCLK1-IN-2 (Compound I-5) is a potent inhibitor of DCLK1, exhibiting an IC50 of 171.3 nM, and demonstrates significant antiproliferative effects on SW1990 cellFórmula:C26H32N8O3SCor e Forma:SolidPeso molecular:536.65Z-DEVD-CMK
CAS:Z-DEVD-CMK irreversibly inhibits various cathepsins in vitro [1].Fórmula:C27H35ClN4O12Cor e Forma:SolidPeso molecular:643.04Ecallantide
CAS:Ecallantide (DX-88) is a recombinant inhibitor specifically targeting plasma kallikrein, which serves to impede the synthesis of bradykinin.Fórmula:C305H448N88O91S8Cor e Forma:SolidPeso molecular:7059.88MeOSuc-AAPV-CMK
CAS:MeOSuc-AAPV-CMK (Elastase Inhibitor III) serves as an inhibitor of elastase, as well as cathepsin G and proteinase 3, and impedes leukocyte elastase-mediatedFórmula:C22H35ClN4O7Cor e Forma:SolidPeso molecular:502.99(1R,4S)-Yimitasvir diphosphate
CAS:Yimitasvir diphosphate, also known as Emitasvir, is an orally-administered inhibitor of the hepatitis C virus (HCV) nonstructural protein 5A (NS5A).Fórmula:C49H64N8O14P2Cor e Forma:SolidPeso molecular:1051.03DS-1040 Tosylate
CAS:DS-1040 Tosylate is a thrombin-activated fibrinolysis inhibitor (TAFI) inhibitor and a fibrinolysis enhancer, used for researching thromboembolic diseases.Fórmula:C23H35N3O5SCor e Forma:SolidPeso molecular:465.61HCV-IN-44
CAS:HCV-IN-44 (compound 28) is an inhibitor of the HCV NS5B protein, efficacious in suppressing HCV virus replication and useful for researching HCV infection [1].Fórmula:C24H26FN3O5SCor e Forma:SolidPeso molecular:487.54GS-6620
CAS:GS-6620 is a HCV nonstructural protein 5B (NS5B) inhibitor.Fórmula:C29H37N6O9PCor e Forma:SolidPeso molecular:644.61Ro 32-7315
CAS:Ro 32-7315 is a selective inhibitor of ADAM17.Fórmula:C22H35N3O5SPureza:98%Cor e Forma:SolidPeso molecular:453.6LM-030
CAS:LM-030, also known as BPR277, is a novel inhibitor of kallikrein-related peptidase 7 (KLK7) and epidermal elastase 2 (ELA2).Fórmula:C46H72N8O12Cor e Forma:SolidPeso molecular:929.11Dim16
CAS:Dim16, a dual inhibitor of PCSK9/HMG-CoAR, demonstrates potent activity with an IC50 of 19 nM against PCSK9 and significantly impedes PCSK9-LDLR interactionFórmula:C29H38IN5Cor e Forma:SolidPeso molecular:583.55Berotralstat HCl
CAS:Berotralstat HCl is a selective plasma kallikrein inhibitor, reducing pain and swelling in HAE by blocking bradykinin release.Fórmula:C30H28Cl2F4N6OCor e Forma:SolidPeso molecular:635.4886HCV-IN-43
CAS:HCV-IN-43 (compound 2), an HCV NS5B protein inhibitor, efficiently inhibits HCV virus replication and is utilized in the study of HCV infection [1].Fórmula:C26H26FN3O5SCor e Forma:SolidPeso molecular:511.57Kallikrein-IN-2
CAS:Kallikrein-IN-2 (compound 1) is an inhibitor of the kinin-releasing enzyme Kallikrein.Fórmula:C28H25F3N4O4Cor e Forma:SolidPeso molecular:538.52Proteasome-IN-4
Proteasome-IN-4, a potent non-covalent inhibitor (IC50=8.39nM), halts cancer cell growth, useful for oncology studies.Fórmula:C44H58N6O5Cor e Forma:SolidPeso molecular:750.97Collagen proline hydroxylase inhibitor-1
CAS:Collagen proline hydroxylase inhibitor-1 具有抗纤维增生活性。Fórmula:C24H21N5O4Pureza:99.57%Cor e Forma:SolidPeso molecular:443.45BMS-212122
CAS:BMS-212122 inhibits MTP, reduces lipids and plaque in animal tests.Fórmula:C43H36F6N4O2Pureza:99.85%Cor e Forma:SolidPeso molecular:754.76Ref: TM-T30506
1mg315,00€5mg745,00€10mg1.018,00€25mg1.431,00€50mg1.783,00€100mg2.250,00€500mg4.410,00€MK-0674
CAS:MK-0674 is a cathepsin K inhibitor (IC50: 0.4 nM) that inhibits Cat B, Cat F, Cat L, and Cat S for metabolism-related diseases.Fórmula:C26H27F6N3O2Pureza:97.3% - 99.91%Cor e Forma:SolidPeso molecular:527.5Nesbuvir
CAS:Nesbuvir: HCV NS5B polymerase inhibitor, IC50 9 nM against HCV 1b replicon in liver cancer cells.Fórmula:C22H23FN2O5SPureza:99.99%Cor e Forma:SolidPeso molecular:446.49Ref: TM-TQ0090
1mg60,00€2mg88,00€5mg133,00€1mL*10mM (DMSO)147,00€10mg173,00€25mg301,00€50mg442,00€100mg577,00€200mg780,00€HIV-1 inhibitor-54
CAS:HIV-1 inhibitor-54: potent anti-HIV (EC50: 32 nM), targets WT HIV-1 IIIB in MT-4 cells for infection research.Fórmula:C27H30N6O4SPureza:98.05% - 99.39%Cor e Forma:SoildPeso molecular:534.63ZED-1227
CAS:ZED-1227 (TAK-227) is a TG2 inhibitor with anticancer activity that blocks inflammation-induced TG2 expression and activation for the treatment of Celiac Diseas
Fórmula:C26H36N6O6Pureza:99.04%Cor e Forma:SolidPeso molecular:528.6Aderamastat
CAS:Aderamastat (FP-025) is an orally active matrix metalloproteinase 12 (MMP-12) inhibitor indicated for the study of allergic asthma, COPD and pulmonary fibrosis.Fórmula:C21H18N2O4SPureza:99.35%Cor e Forma:SolidPeso molecular:394.44γ-Glu-Tyr
CAS:gamma-Glu-Tyr (gamma-Glutamyltyrosine) is a kokumi peptide against dipeptidyl peptidase-IV (DPP-IV) and is used in the study of diabetes mellitus.Fórmula:C14H18N2O6Pureza:98.92%Cor e Forma:SolidPeso molecular:310.3VBY-825
CAS:VBY-825 is a reversible inhibitor of cathepsin with high potency against cathepsins B, L, S and V.Fórmula:C23H29F4N3O5SPureza:99.91%Cor e Forma:SolidPeso molecular:535.55Belactin A
CAS:Belactin A acts as an inhibitor of vasohibin-1 [VASH-1] with an IC50 of 0.18 µg/ml.Fórmula:C17H21ClN2O4Cor e Forma:SolidPeso molecular:352.81Idraparinux Na
CAS:Idraparinux Na is an Antithrombotic, Indirect, Selective, Synthetic Factor Xa InhibitorFórmula:C38H55Na9O49S7Cor e Forma:SolidPeso molecular:1727.14HCV-IN-7
CAS:HCV-IN-7: potent oral HCV NS5A inhibitor, pan-genotypic, IC50s 3-47 pM, good pharmacokinetics, favorable liver uptake.Fórmula:C40H48N8O6SPureza:98%Cor e Forma:SolidPeso molecular:768.92Tyrosinase-IN-20
CAS:Tyrosinase-IN-20 (compound 6a) acts as a potent Tyrosinase inhibitor, demonstrating an IC 50 value of 28.50 μM [1].Fórmula:C17H18N2O2SCor e Forma:SolidPeso molecular:314.4RDN2150
CAS:RDN2150 (Compound 25), a ZAP-70 inhibitor with an IC50 of 14.6 nM, covalently binds to the C346 residue of ZAP-70, suppressing the expression of CD25 and CD69Fórmula:C28H29ClN8O4Cor e Forma:SolidPeso molecular:577.03JBIR-22
CAS:JBIR-22 is a natural inhibitor for protein−protein interaction of the homodimer of proteasome assembly factor 3.Fórmula:C23H33NO6Cor e Forma:SolidPeso molecular:419.51TMPRSS6-IN-1 TFA
TMPRSS6-IN-1 (TFA) is a potent inhibitor of TMPRSS6 (Matriptase-2), a member of the TTSP family (a type of transmembrane serine protease). TMPRSS6 is a type II TTSP, and genetically reduced levels of TMPRSS6 have been shown to improve symptoms of hemochromatosis and β-thalassemia in mice.Fórmula:C35H41F3N8O6S2Cor e Forma:SolidPeso molecular:790.875BI-1915
CAS:BI-1915 is a selective inhibitor of Cathepsin S, with an IC50 of 17 nM. It is utilized in the research of autoimmune diseases.Fórmula:C21H37N5O3Cor e Forma:SolidPeso molecular:407.55Valopicitabine dihydrochloride
CAS:Valopicitabine, a NS5B inhibitor, is used potentially for the treatment of HCV infection.Fórmula:C15H25ClN4O6Cor e Forma:SolidPeso molecular:392.84AEP-IN-1
APE-IN-1, a potent AEP inhibitor (IC50: 89 nM), aids Alzheimer's diagnosis and drug research.Fórmula:C18H27N3O3Cor e Forma:SolidPeso molecular:333.43CM-352
CAS:CM-352 is a metalloproteinase inhibitor that reduces brain damage and improves functional recovery in rat models of cerebral hemorrhage.Fórmula:C24H29N3O6SPureza:97.24%Cor e Forma:SolidPeso molecular:487.57Monosodium 2-sulfoterephthalate
CAS:Monosodium 2-sulfoterephthalate (8) is an inhibitor of glutamate carboxypeptidase II.
Fórmula:C8H5NaO7SCor e Forma:SolidPeso molecular:268.176SSR-182289A (Free)
CAS:SSR-182289A (Free) is a thrombin inhibitor.Fórmula:C30H33F2N5O4SPureza:98%Cor e Forma:SolidPeso molecular:597.68Antiplatelet agent 3
CAS:Antiplatelet agent 3 (Compound K-10) is a compound with antiplatelet aggregation activity, exhibiting IC50 values of 2.55, 3.22, and 2.09 mg/mL for platelet aggregation induced by ADP, AA, and COL, respectively. It holds potential for research in cardiovascular diseases.Fórmula:C38H32N2O5Cor e Forma:SolidPeso molecular:596.671Cathepsin C-IN-5
CAS:Cathepsin C-IN-5 (SF38) is a potent, oral Cathepsin C blocker with an IC50 of 59.9 nM; less active against Cat L/S/B/K; has anti-inflammatory effects.Fórmula:C21H17ClN6OSCor e Forma:SolidPeso molecular:436.92Gemigliptin tartrate hydrate
CAS:Gemigliptin (LC15-0444) tartrate hydrate is a selective, reversible, and competitive inhibitor of dipeptidyl peptidase 4 (DPP-4), with an IC50 value of 10.3 nM for human recombinant DPP-4. It exhibits strong anti-glycation properties and is used in research on advanced glycation end product-related diabetic complications.Fórmula:C22H27F8N5O9Cor e Forma:SolidPeso molecular:657.47Plodicitinib
CAS:Plodicitinib is an inhibitor of Janus tyrosine kinase 3/TEC family kinase, exhibiting anti-inflammatory properties.Fórmula:C19H22FN7O2Cor e Forma:SolidPeso molecular:399.422RXP03
CAS:RXP03 is an MMPs inhibitor with K_i values of 20 nM for MMP-2, 2.5 nM for MMP-8, 10 nM for MMP-9, 5 nM for MMP-11, and 105 nM for MMP-14 [1].Fórmula:C39H43N4O6PCor e Forma:SolidPeso molecular:694.76ABT-072
CAS:ABT-072 is a nonnucleoside NS5B polymerase inhibitor and a candidate drug evaluated for treatment of hepatitis C virus.Fórmula:C24H27N3O5SPureza:98%Cor e Forma:SolidPeso molecular:469.55Cyclophilin inhibitor 1
CAS:Cyclophilin inhibitor 1: orally available, Kd 5 nM, potent against HCV, EC50 for HCV 2a is 98 nM.Fórmula:C31H39N5O7Pureza:98%Cor e Forma:SolidPeso molecular:593.67Dup-714
CAS:Dup-714 is a thrombin inhibitor.Fórmula:C21H33BN6O5Pureza:98%Cor e Forma:SolidPeso molecular:460.33BMT-052
CAS:BMT-052 is a potent and selective Pan-genotypic HCV NS5B Polymerase Inhibitor (EC50 = 7 nM).Fórmula:C30H17D9F4N6O5Pureza:98%Cor e Forma:SolidPeso molecular:635.61Faldaprevir sodium
CAS:Faldaprevir sodium: HCV treatment, inhibits NS3/NS4A protease, P-glycoprotein, CYP3A4, UGT1A1.Fórmula:C40H48BrN6NaO9SCor e Forma:SolidPeso molecular:891.81Ciluprevir
CAS:Ciluprevir is a selective HCV NS3 protease inhibitor, effective against non-genotype-1 HCV; less potent for genotypes 2/3.Fórmula:C40H50N6O8SPureza:98%Cor e Forma:SolidPeso molecular:774.93Pyridoxatin
CAS:Pyridoxatin: fungal metabolite; blocks TBARS production, prevents AAPH-induced hemolysis, and acts against C. albicans.Fórmula:C15H21NO3Cor e Forma:SolidPeso molecular:263.33PLGLAG
CAS:PLGLAG is a peptide chain that acts as a linker in activatable cell-penetrating peptides (ACPPs). ACPPs containing the PLGLAG linker are primarily sensitive to MMP-2 and MMP-9 in vivo. PLGLAG is applicable in cancer research.Fórmula:C24H42N6O7Cor e Forma:SolidPeso molecular:526.63Cathepsin C-IN-3
Cathepsin C-IN-3 is a potent inhibitor of histone C (IC50: 61.79 nM) and also inhibits THP-1 cells (IC50: 101.5 nM) and U937 cells (IC50: 86.5 nM).Fórmula:C28H21F3N6OSCor e Forma:SolidPeso molecular:546.57Piceid 6″-O-azelaic acid ester
Piceid 6″-O-azelaic acid ester exhibited strong intracellular tyrosinase inhibition and decolorization activity.Fórmula:C24H36O10Cor e Forma:SolidPeso molecular:484.54
