Proteases/Proteassoma

Os inibidores de proteases e proteassomas são compostos que bloqueiam a atividade das proteases e do proteassoma, que estão envolvidos na degradação e renovação de proteínas. Esses inibidores são vitais para estudar a regulação da homeostase de proteínas, controle do ciclo celular e apoptose. Inibidores de proteases e proteassomas também são utilizados no tratamento de doenças como o câncer, onde a degradação anormal de proteínas desempenha um papel na progressão da doença. Ao inibir proteases ou o proteassoma, esses compostos podem induzir a morte celular em células cancerígenas e são ferramentas essenciais tanto na pesquisa básica quanto no desenvolvimento terapêutico. Na CymitQuimica, oferecemos uma ampla gama de inibidores de proteases e proteassomas de alta qualidade para apoiar sua pesquisa em bioquímica, biologia celular e desenvolvimento de medicamentos.

Subcategorias de "Proteases/Proteassoma"

Exibir 3 mais subcategorias

Foram encontrados 1044 produtos de "Proteases/Proteassoma"

Pureza (%)

100

produtos por página.

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CL 82198 hydrochloride
CAS:
- 1188890-36-9
CL 82198 hydrochloride selectively inhibits MMP-13, not MMP-1/9/TACE, and blocks HP75 invasion and neurotoxicity in zebrafish.
Fórmula:C₁₇H₂₃ClN₂O₃
Cor e Forma:Solid
Peso molecular:338.83
Ref: TM-T41179
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Acetyl-Calpastatin(184-210)(human)
CAS:
- 123714-50-1
Calpain inhibitor, Ki 0.2 nM for calpain I/II, doesn't affect papain/trypsin/cat L. Raises Aβ42, Aβ40 secretion & Aβ42/Aβ40 ratio.
Fórmula:C₁₄₂H₂₃₀N₃₆O₄₄S
Pureza:98%
Cor e Forma:Solid
Peso molecular:3177.65
Ref: TM-TP2056
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Ecallantide TFA
Ecallantide (DX-88) TFA, a specific recombinant plasma kallikrein inhibitor, directly inhibits bradykinin production and is indicated for the prevention of
Cor e Forma:Odour Solid
Ref: TM-T82510
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AP-C2
CAS:
- 682793-07-3
AP-C2 is a potent small molecule guanosine 3',5'-cyclic monophosphate (cGMP)-dependent protein kinase II (cGKII) inhibitor with a pIC50 of 5.2 for cGKII.
Fórmula:C₁₈H₁₆N₄S
Pureza:99.87%
Cor e Forma:Soild
Peso molecular:320.41
Ref: TM-T77570
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C-telopeptide
CAS:
- 162929-64-8
C-telopeptide from type I collagen is released during bone resorption; it correlates with bone mineral density.
Fórmula:C₃₄H₅₆N₁₄O₁₃
Pureza:98%
Cor e Forma:Solid
Peso molecular:868.9
Ref: TM-TP1779
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Tyrosinase-IN-32
Tyrosinase-IN-32 (compound 11), a hydroxamate-based alkaloid extracted from black pepper (Piper nigrum L.), functions as an inhibitor of mushroom tyrosinase. In addition to its inhibitory properties, it exhibits antioxidant activity.
Fórmula:C₁₅H₁₉NO₃
Cor e Forma:Solid
Peso molecular:261.32
Ref: TM-TN8160
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Anticancer agent 114
Anticancer agent 114: oral dipeptide boronic acid, proteasome inhibitor, IC 50 = 2.2 nM, halts RPMI-8226 cell growth, for multiple myeloma research.
Fórmula:C₂₈H₃₃BF₆N₂O₇
Cor e Forma:Solid
Peso molecular:634.37
Ref: TM-T74839
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Elastatinal
CAS:
- 51798-45-9
Elastatinal is an elastase inhibitor. It is found in culture filtrates of various species of actinomyces.
Fórmula:C₂₁H₃₆N₈O₇
Cor e Forma:Yellowish Solid
Peso molecular:512.56
Ref: TM-T20130
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Ac-DEMEEC-OH
CAS:
- 208921-05-5
Ac-DEMEEC-OH is a competitive inhibitor of the HCV NS3 protease with a Ki of 0.6 µM.
Fórmula:C₂₉H₄₄N₆O₁₆S₂
Cor e Forma:Solid
Peso molecular:796.82
Ref: TM-TP2848
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HIV-1 TAT (48-60) Acetate
Lilotomab (HH1) is a murine anti-CD37 antibody that can be used to synthesize anti-CD37 antibody-radionuclide couplings.
Fórmula:C₇₂H₁₃₅N₃₅O₁₈
Pureza:99.93%
Cor e Forma:Soild
Peso molecular:1779.07
Ref: TM-T75964L
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EP 171
CAS:
- 122089-44-5
EP 171 is a potent agonist of TP-receptors.
Fórmula:C₂₃H₂₉FO₅
Cor e Forma:Solid
Peso molecular:404.47
Ref: TM-T27273
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STK33-IN-1
CAS:
- 1404437-49-5
STK33-IN-1 (compound 1) is a STK33 inhibitor, with an IC 50 of 7 nM.
Fórmula:C₂₄H₂₇N₇O₂
Cor e Forma:Solid
Peso molecular:445.527
Ref: TM-T38835
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GSK2818713
CAS:
- 1422484-32-9
GSK2818713 is a novel Hepatitis C NS5A replication complex inhibitor.
Fórmula:C₄₆H₅₆N₈O₈
Cor e Forma:Solid
Peso molecular:849.002
Ref: TM-T38858
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BMS-767778
CAS:
- 915729-95-2
BMS-767778, a DPP-4 inhibitor, is used potentially for the treatment of type 2 diabetes.
Fórmula:C₁₉H₂₀Cl₂N₄O₂
Cor e Forma:Solid
Peso molecular:407.29
Ref: TM-T26857
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Linagliptin Methyldimer
CAS:
- 1418133-47-7
Linagliptin Methyldimer is a potent dipeptidyl peptidase IV inhibitor, IC50=6 pM.
Fórmula:C₅₀H₅₆N₁₆O₄
Pureza:97.23%
Cor e Forma:Solid
Peso molecular:945.08
Ref: TM-T67852
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RXP470
CAS:
- 891198-31-5
RXP470 is a potent and selective MMP-12 inhibitor (Ki 0.24 nM).
Fórmula:C₃₅H₃₅BrClN₄O₁₀P
Cor e Forma:Solid
Peso molecular:818
Ref: TM-T28633
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Plasma kallikrein-IN-1
CAS:
- 2691030-28-9
Plasma kallikrein-IN-1 is a PKK inhibitor with an IC 50 value of 0.5 nM.
Fórmula:C₂₃H₂₅F₂N₇O
Cor e Forma:Solid
Peso molecular:453.498
Ref: TM-T40312
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FiVe1
CAS:
- 932359-76-7
FiVe1 is a vimentin-binding compound that disrupts mitosis in cancer cells, causing cell death, with an IC50 of 234 nM in FOXC2-HMLER.
Fórmula:C₁₈H₁₆Cl₂N₄
Pureza:99.67%
Cor e Forma:Solid
Peso molecular:359.25
Ref: TM-T9657
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Paritaprevir dihydrate
CAS:
- 1456607-71-8
Paritaprevir dihydrate: potent oral HCV NS3/4A inhibitor (EC50: 0.21-1 nM), SARS-CoV-3CL blocker (IC50: 1.31 μM), metabolized by CYP3A, boosted by Ritonavir.
Fórmula:C₄₀H₄₇N₇O₉S
Cor e Forma:Solid
Peso molecular:801.91
Ref: TM-T73898
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CTTHWGFTLC, CYCLIC
CAS:
- 244082-19-7
CTT Gelatinase Inhibitor peptide blocks MMP-2/9, hindering cancer by stopping tumor growth.
Fórmula:C₅₂H₇₁N₁₃O₁₄S₂
Pureza:98%
Cor e Forma:Solid
Peso molecular:1166.33
Ref: TM-TP1501