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Proteases/Proteassoma

Proteases/Proteassoma

Os inibidores de proteases e proteassomas são compostos que bloqueiam a atividade das proteases e do proteassoma, que estão envolvidos na degradação e renovação de proteínas. Esses inibidores são vitais para estudar a regulação da homeostase de proteínas, controle do ciclo celular e apoptose. Inibidores de proteases e proteassomas também são utilizados no tratamento de doenças como o câncer, onde a degradação anormal de proteínas desempenha um papel na progressão da doença. Ao inibir proteases ou o proteassoma, esses compostos podem induzir a morte celular em células cancerígenas e são ferramentas essenciais tanto na pesquisa básica quanto no desenvolvimento terapêutico. Na CymitQuimica, oferecemos uma ampla gama de inibidores de proteases e proteassomas de alta qualidade para apoiar sua pesquisa em bioquímica, biologia celular e desenvolvimento de medicamentos.

Subcategorias de "Proteases/Proteassoma"

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Foram encontrados 1044 produtos de "Proteases/Proteassoma"

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  • TCH-165
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    TCH-165

    CAS:
    <p>TCH-165 boosts 20S proteasome levels, enhancing IDP breakdown.</p>
    Fórmula:C39H37N3O3
    Pureza:98.2% - 98.75%
    Cor e Forma:Solid
    Peso molecular:595.73

    Ref: TM-T17011

  • Bemnifosbuvir hemisulfate
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    Bemnifosbuvir hemisulfate

    CAS:
    <p>Bemnifosbuvir hemisulfate (AT-527) is a potent inhibitor of HCV virus replication.</p>
    Fórmula:C48H68F2N14O18P2S
    Pureza:99.98%
    Cor e Forma:Solid
    Peso molecular:1261.15

    Ref: TM-T9331

  • Lusutrombopag
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    Lusutrombopag

    CAS:
    <p>Lusutrombopag (Mulpleta) is an orally bioavailable, small molecule thrombopoietin (TPO) receptor agonist for chronic liver disease (CLD) patients with</p>
    Fórmula:C29H32Cl2N2O5S
    Pureza:99.96%
    Cor e Forma:Solid
    Peso molecular:591.55

    Ref: TM-TQ0223

  • TAPI-1 trifluoroacetate (163847-77-6(free base))
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    TAPI-1 trifluoroacetate (163847-77-6(free base))

    TAPI-1 is an ADAM17/TACE inhibitor, which blocks shedding of cytokine receptors.
    Fórmula:C28H38F3N5O7
    Pureza:98.06%
    Cor e Forma:Solid
    Peso molecular:613.62

    Ref: TM-T4122

  • LY 3000328
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    LY 3000328

    CAS:
    <p>LY 3000328 (Cathepsin S inhibitor) is a selective inhibitor of cathepsin S.Cost-effective and quality-assured.</p>
    Fórmula:C25H29FN4O5
    Pureza:97.83% - 99.54%
    Cor e Forma:Solid
    Peso molecular:484.52

    Ref: TM-TQ0116

  • Daclatasvir dihydrochloride
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    Daclatasvir dihydrochloride

    CAS:
    <p>Daclatasvir dihydrochloride is an oral antiviral that treats chronic hepatitis C by inhibiting HCV's NS5A; rare liver enzyme elevation, seldom causes jaundice.</p>
    Fórmula:C40H52Cl2N8O6
    Pureza:99.67%
    Cor e Forma:Solid
    Peso molecular:811.8

    Ref: TM-T1786

  • S 3304
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    S 3304

    CAS:
    <p>S 3304 is a novel matrix metalloproteinases inhibitor which is specific for MMP-2 and MMP-9.</p>
    Fórmula:C24H20N2O4S2
    Pureza:98.09%
    Cor e Forma:Solid
    Peso molecular:464.56

    Ref: TM-T16966

  • Etravirine
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    Etravirine

    CAS:
    <p>Etravirine (R165335) is a diarylpyrimidine non-nucleoside reverse transcriptase inhibitor.</p>
    Fórmula:C20H15BrN6O
    Pureza:97.61% - 99.74%
    Cor e Forma:White To Off-White Solid
    Peso molecular:435.28

    Ref: TM-T2551

  • Dabigatran Etexilate Mesylate
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    Dabigatran Etexilate Mesylate

    CAS:
    <p>Dabigatran Etexilate Mesylate (BIBR 1048MS) is the orally active prodrug of dabigatran. Dabigatran is a reversible and selective, direct thrombin inhibitor.</p>
    Fórmula:C34H41N7O5·CH4O3S
    Pureza:99.91%
    Cor e Forma:Solid
    Peso molecular:723.84

    Ref: TM-T5133

  • CA-074 methyl ester
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    CA-074 methyl ester

    CAS:
    <p>CA-074 methyl ester (Cathepsin B Inhibitor IV) is a selective inhibitor of Cathepsin B (IC50=36.3 nM). neuroprotective effect. High-Quality, Low-Cost!</p>
    Fórmula:C19H31N3O6
    Pureza:97.26% - 99.58%
    Cor e Forma:Solid
    Peso molecular:397.47

    Ref: TM-T3420

  • Peptide T acetate(106362-32-7 free base)
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    Peptide T acetate(106362-32-7 free base)

    <p>Peptide T acetate is an octapeptide from the V2 region of HIV-1 gp120.</p>
    Fórmula:C37H59N9O18
    Pureza:99.47%
    Cor e Forma:Solid
    Peso molecular:917.91

    Ref: TM-TP1785L

  • Letermovir
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    Letermovir

    CAS:
    <p>Letermovir (AIC246) (AIC246) is a novel anti-CMV compound (EC50: about 5 nM in fibroblast cells). It targets the pUL56 subunit of the viral terminase complex.</p>
    Fórmula:C29H28F4N4O4
    Pureza:99.85% - 99.87%
    Cor e Forma:Solid
    Peso molecular:572.55

    Ref: TM-T5396

  • (S,S)-TAPI-1
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    (S,S)-TAPI-1

    CAS:
    <p>"(S,S)-TAPI-1, an isomer of TAPI-1, inhibits MMPs and TACE (ADAM17), reducing cell surface protein shedding."</p>
    Fórmula:C26H37N5O5
    Cor e Forma:Solid
    Peso molecular:499.6

    Ref: TM-T63390

  • PTACH
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    PTACH

    CAS:
    PTACH (Cpd 51) (NCH-51) is a SAHA-based inhibitor of human HDAC. It can potently inhibit the growth of various human Y cells (EC50: 1 to 10 μM).
    Fórmula:C20H26N2O2S2
    Pureza:87.44% - 99.74%
    Cor e Forma:Solid
    Peso molecular:390.56

    Ref: TM-T3199

  • Darunavir
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    Darunavir

    CAS:
    <p>Darunavir (TMC114) is an HIV PROTEASE INHIBITOR that is used in the treatment of AIDS and HIV INFECTIONS.</p>
    Fórmula:C27H37N3O7S
    Pureza:99.67% - 99.76%
    Cor e Forma:White Amorphous Solid
    Peso molecular:547.66

    Ref: TM-T2324

  • Coblopasvir dihydrochloride
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    Coblopasvir dihydrochloride

    CAS:
    <p>Coblopasvir dihydrochloride can be used to study chronic HCV infection and is a pan-genotypic nonstructural protein 5A (NS5A) inhibitor.</p>
    Fórmula:C41H52Cl2N8O8
    Pureza:99.33%
    Cor e Forma:Solid
    Peso molecular:855.81

    Ref: TM-T25268L

  • Bemnifosbuvir
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    Bemnifosbuvir

    CAS:
    <p>Bemnifosbuvir (AT-511) is a novel phosphoramidate prodrug of 2'-fluoro-2'-C-methylguanosine-5'-monophosphate that has potent in vitro activity against HCV.</p>
    Fórmula:C24H33FN7O7P
    Pureza:99.35% - 99.54%
    Cor e Forma:Solid
    Peso molecular:581.53

    Ref: TM-T9341

  • PSI-6130
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    PSI-6130

    CAS:
    <p>PSI-6130 (R 1656) is a potent and selective HCV NS5B polymerase inhibitor. PSI-6130 inhibits HCV replication with a mean IC50 of 0.6 μM.</p>
    Fórmula:C10H14FN3O4
    Pureza:98.63% - 99.79%
    Cor e Forma:Solid
    Peso molecular:259.23

    Ref: TM-T7607

  • Asunaprevir
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    Asunaprevir

    CAS:
    <p>Asunaprevir (BMS-650032) is an effective hepatitis C virus (HCV) NS3 protease inhibitor.</p>
    Fórmula:C35H46ClN5O9S
    Pureza:99.34% - 99.8%
    Cor e Forma:Solid
    Peso molecular:748.29

    Ref: TM-T4474

  • XMD8-87
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    XMD8-87

    CAS:
    <p>XMD8-87 (ACK1-B19), a TNK2 inhibitor, strongly blocks TNK2 phosphorylation and mutations in tumors.</p>
    Fórmula:C24H27N7O2
    Pureza:98.05% - 99.89%
    Cor e Forma:Solid
    Peso molecular:445.52

    Ref: TM-T3709