Proteases/Proteassoma
Os inibidores de proteases e proteassomas são compostos que bloqueiam a atividade das proteases e do proteassoma, que estão envolvidos na degradação e renovação de proteínas. Esses inibidores são vitais para estudar a regulação da homeostase de proteínas, controle do ciclo celular e apoptose. Inibidores de proteases e proteassomas também são utilizados no tratamento de doenças como o câncer, onde a degradação anormal de proteínas desempenha um papel na progressão da doença. Ao inibir proteases ou o proteassoma, esses compostos podem induzir a morte celular em células cancerígenas e são ferramentas essenciais tanto na pesquisa básica quanto no desenvolvimento terapêutico. Na CymitQuimica, oferecemos uma ampla gama de inibidores de proteases e proteassomas de alta qualidade para apoiar sua pesquisa em bioquímica, biologia celular e desenvolvimento de medicamentos.
Subcategorias de "Proteases/Proteassoma"
- Acetil- CoA Carboxilase(34 produtos)
- Cisteína Protease(96 produtos)
- DPP-4(20 produtos)
- Glutaminase(40 produtos)
- HIV Protease(449 produtos)
- PAI-1(25 produtos)
- Inibidores de Protease(50 produtos)
- Receptor activado por protease(53 produtos)
- Proteassoma(94 produtos)
- Protease serina(50 produtos)
- p97(14 produtos)
Exibir 3 mais subcategorias
Foram encontrados 1044 produtos de "Proteases/Proteassoma"
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Zampilimab
CAS:<p>Zampilimab (UCB-7858) is a humanised monoclonal antibody targeting TGM2, inhibits the cross-linking transamidase activity of TG2, renal fibrosis.</p>Pureza:95%Cor e Forma:LiquidHCV-IN-30
CAS:<p>HCV-IN-30 is an HCV NS5A replication complex inhibitor (IC50s: 901 and 102 nM for genotypes 1a and 1b replicons).</p>Fórmula:C36H44N6O4Pureza:99.6%Cor e Forma:SolidPeso molecular:624.77Carboxypeptidase G2 (CPG2) Inhibitor
CAS:<p>Carboxypeptidase G2 (CPG2) Inhibitor (CPG2 Inhibitor) is a new CPG2 Inhibitor with antitumor activity.</p>Fórmula:C13H15NO6SPureza:99.96%Cor e Forma:SolidPeso molecular:313.33Cathepsin Inhibitor 1
CAS:<p>Cathepsin Inhibitor 1 is an inhibitor of Cathepsin (L, L2, S, K, B) with pIC50 of 7.9, 6.7, 6.0, 5.5 and 5.2, respectively.</p>Fórmula:C20H24ClN5O2Pureza:99.78%Cor e Forma:SolidPeso molecular:401.89A-933548
CAS:<p>A-933548: potent calpain inhibitor, selective vs. cathepsins, stable, effective in cell assays.</p>Fórmula:C25H21N5O3Pureza:98%Cor e Forma:SolidPeso molecular:439.47Cysteine Protease inhibitor hydrochloride
CAS:<p>Cysteine Protease inhibitor hydrochloride is a cysteine protease inhibitor.</p>Fórmula:C18H15ClN4OPureza:98%Cor e Forma:SolidPeso molecular:338.79Tec-IN-21
CAS:<p>Tec-IN-21 is an inhibitor of Tec kinase, it also blocks unconventional secretion of fibroblast growth factor 2 (FGF2).</p>Fórmula:C16H15ClN4O2SPureza:98%Cor e Forma:SolidPeso molecular:362.83Sheng Gelieting
CAS:<p>CGT-8012 inhibits DP-IV enzyme, aiding type II diabetes research, with an IC50 of 87 nM.</p>Fórmula:C17H16F6N4OCor e Forma:SolidPeso molecular:406.33CP-471474
CAS:<p>MMP inhibitor with IC50: MMP-2 (0.7 nM), MMP-13 (0.9 nM), MMP-9 (13 nM), MMP-3 (16 nM), MMP-1 (1170 nM); reduces heart dilation post-infarct.</p>Fórmula:C16H17FN2O5SPureza:98%Cor e Forma:SolidPeso molecular:368.38AGLME
CAS:<p>AGLME is used in a direct enzymatic assay for activated Hageman factor measuring the ability of Hageman factor to hydrolyze the cpd.</p>Fórmula:C11H21N3O4Cor e Forma:SolidPeso molecular:259.3SJA6017
CAS:<p>SJA6017: inhibits calpain-1/2, cathepsins B/L; prevents apoptosis, protects spinal cord, boosts function. IC50s: 7.5-78 nM.</p>Fórmula:C17H25FN2O4SPureza:98%Cor e Forma:SolidPeso molecular:372.45SQ 32602
CAS:<p>SQ 32602 is a cathepsin E inhibitor.</p>Fórmula:C32H52N3O7PCor e Forma:SolidPeso molecular:621.74Tyrosinase-IN-8
<p>Tyrosinase-IN-8, a potent inhibitor of tyrosinase, demonstrates an inhibitory concentration (IC 50) value of 1.6 µM and exhibits low cytotoxicity while</p>Fórmula:C16H12O4Cor e Forma:SolidPeso molecular:268.26DPP-4-IN-2
CAS:<p>DPP-4-IN-2, analog of Alogliptin with 79 nM IC50, is a research tool for diabetes.</p>Fórmula:C18H18N6OCor e Forma:SolidPeso molecular:334.38Alvelestat tosylate
CAS:Alvelestat can inhibit neutrophil elastase (NE), which acts an important role in NET formation.Fórmula:C32H30F3N5O7S2Pureza:98%Cor e Forma:SolidPeso molecular:717.73Thrombin Inhibitor 2
CAS:<p>Thrombin Inhibitor 2 is a small molecule direct thrombin inhibitor. Thrombin Inhibitor 2 has antithrombotic activity.</p>Fórmula:C19H16ClF3N6O2Pureza:98%Cor e Forma:SolidPeso molecular:452.82(Rac)-Tanomastat
CAS:<p>Tanomastat (BAY 12-9566) is an oral biphenyl MMP inhibitor; blocks MMP-2, -3, -9, -13, with anti-invasive and anti-metastatic properties.</p>Fórmula:C23H19ClO3SCor e Forma:SolidPeso molecular:410.91PSI-7409 tetrasodium
CAS:<p>PSI-7409 tetrasodium, a sofosbuvir metabolite, inhibits GT 1b, 2a, 3a, 4a NS5B polymerases with IC50s of 1.6, 2.8, 0.7, 2.6 μM.</p>Fórmula:C10H16FN2Na4O14P3Pureza:98%Cor e Forma:SolidPeso molecular:592.117Evogliptin HCl
CAS:<p>Evogliptin (DA-1229), a DPP4 inhibitor, enhances insulin sensitivity and delays diabetes onset.</p>Fórmula:C19H27ClF3N3O3Cor e Forma:SolidPeso molecular:437.88LY 806303
CAS:<p>LY 806303 is a highly selective thrombin inhibitor.</p>Fórmula:C16H14O5SPureza:98%Cor e Forma:SolidPeso molecular:318.34Nucleoside-Analog-2
CAS:<p>Nucleoside-Analog-2 is a 4'-Azidocytidine analogue, used to against Hepatitis C virus (HCV) replication.</p>Fórmula:C9H11N5O6Pureza:98%Cor e Forma:SolidPeso molecular:285.21BI-L 45XX
CAS:<p>BI-L 45XX, an anti-inflammatory benzimidazole derivative, has inhibitory effects on neutrophil function.</p>Fórmula:C10H9F3N2O2SCor e Forma:SolidPeso molecular:278.25Tyrphostin 47
CAS:<p>Tyrphostin 47 inhibits the protein-tyrosine kinase activity of EGF-R.</p>Fórmula:C10H8N2O2SCor e Forma:SolidPeso molecular:220.25Levovirin valinate HCl
CAS:<p>Levovirin valinate HCl is a valine ester prodrug of levovirin as a new investigational drug for the therapy of the hepatitis C virus.</p>Fórmula:C13H22ClN5O6Pureza:98%Cor e Forma:SolidPeso molecular:379.8Ici 186756
CAS:<p>Ici 186756 is a novel, effective, and selective inhibitor of human neutrophil elastase.</p>Fórmula:C33H49N5O9Pureza:98%Cor e Forma:SolidPeso molecular:659.77Chymase-IN-2
CAS:<p>Chymase-IN-2 is a modulator of chymase.</p>Fórmula:C19H15ClF2NO3PSPureza:98%Cor e Forma:SolidPeso molecular:441.82A-953227
CAS:<p>A-953227: Selective calpain inhibitor with improved cathepsin selectivity, strong microsomal stability, and cellular efficacy.</p>Fórmula:C25H20FN5O3Pureza:98%Cor e Forma:SolidPeso molecular:457.46Duazomycin
CAS:<p>Duazomycin, an antitumor substance and glutamine antagonist, is used as a chemotherapeutic agent.</p>Fórmula:C8H11N3O4Cor e Forma:SolidPeso molecular:213.19Moxicoumone
CAS:<p>Moxicoumone is an anticoagulant agent.</p>Fórmula:C22H30N2O6Pureza:98%Cor e Forma:SolidPeso molecular:418.48GLS1 Inhibitor
CAS:<p>GLS1 inhibitor blocks glutaminase 1 (IC50=0.021 μM), hinders NCI H1703 NSCLC cell growth in vitro (GI50=0.011 μM), and suppresses tumors in mice.</p>Fórmula:C19H21N7O2SCor e Forma:SolidPeso molecular:411.48Tyrphostin A46
CAS:<p>Tyrphostin A46 is an antagonist of the epidermal growth factor-urogastrone receptor.</p>Fórmula:C10H8N2O3Pureza:98%Cor e Forma:Off-White SolidPeso molecular:204.18NVP DPP 728 dihydrochloride
CAS:<p>NVP-DPP728 is a reversible DPP-IV inhibitor with a K i of 11 nM, enhancing insulin release by preventing GLP-1 degradation, used for diabetes research.</p>Fórmula:C15H18N6OCor e Forma:SolidPeso molecular:298.34MDK0734
CAS:<p>MDK0734 is a selective inhibitor of cathepsin B endopeptidase and exopeptidase activities.</p>Fórmula:C15H17N3O2Pureza:98%Cor e Forma:SolidPeso molecular:271.31Bz-D-Arg-pNA hydrochloride
CAS:<p>Bz-D-Arg-pNA hydrochloride is a competitive trypsin inhibitor.</p>Fórmula:C19H23ClN6O4Cor e Forma:SolidPeso molecular:434.88FQ
CAS:<p>FQ is a novel reversible inhibitor of mixed-type tyrosinase.</p>Fórmula:C14H9FN2OCor e Forma:SolidPeso molecular:240.23ND-336
CAS:<p>ND-336 selectively inhibits MMP-2, MMP-9, MMP-14, boosts diabetic wound healing, reduces inflammation, and promotes angiogenesis and skin repair.</p>Fórmula:C16H18ClNO3S2Cor e Forma:SolidPeso molecular:371.9ADAMTS-5 Inhibitor
CAS:<p>ADAMTS-5 Inhibitor is an inhibitor of ADAMTS-5 with an IC50 of 1.1 µM and can be used in studies about cartilage destruction in arthritis.</p>Fórmula:C16H11ClF3N3OS3Pureza:99.66%Cor e Forma:SolidPeso molecular:449.92DPP-IV-IN-1
CAS:<p>DPP-IV-IN-1 is an effective inhibitor of dipeptidyl peptidase IV (DPP-IV), a serine protease (IC50: 4.6 nM).</p>Fórmula:C11H18FN3O2Pureza:98%Cor e Forma:SolidPeso molecular:243.28TNIK-IN-1
CAS:<p>TNIK-IN-1 is an inhibitor of Traf2- and Nck-interacting kinase (TNIK).</p>Fórmula:C19H17N5O3SPureza:98%Cor e Forma:SolidPeso molecular:395.43Diethyl pyimDC
CAS:<p>Diethyl pyimDC is an inhibitor of human collagen prolyl 4-hydroxylase 1 (CP4H1).</p>Fórmula:C14H15N3O4Cor e Forma:SolidPeso molecular:289.29Aldumastat
CAS:<p>Aldumastat (GLPG1972) is a highly potent, specific and orally active inhibitor of ADAMTS-5.Aldumastat is used for the study of osteoarthritis of the knee.</p>Fórmula:C20H24F2N4O3Pureza:99.87%Cor e Forma:SolidPeso molecular:406.43YM-53601
CAS:<p>YM-53601 is an SQS inhibitor that inhibits adipogenic biosynthesis and lipid secretion in rodents.YM-53601 is a cholesterol-lowering agent that inhibits FDFT1.</p>Fórmula:C21H22ClFN2OPureza:99.65%Cor e Forma:SolidPeso molecular:372.86MK-4882
CAS:<p>MK-4882 is an effective inhibitor of HCV NS5A.</p>Fórmula:C42H50N8O7Pureza:98%Cor e Forma:SolidPeso molecular:778.9Gosogliptin
CAS:<p>Gosogliptin is a potent, orally active, highly selective, reversible and competitive inhibitor of DPP-4, increasing the level of intestinal GLP-1 and GIP.</p>Fórmula:C17H24F2N6OPureza:99.74%Cor e Forma:SolidPeso molecular:366.41Nucleoside-Analog-1
CAS:Nucleoside-Analog-1 is a 4′-Azidocytidine analogue, used to against Hepatitis C virus replication.Fórmula:C9H9N5O5Pureza:98%Cor e Forma:SolidPeso molecular:267.2Sortin1
CAS:<p>Sortin1, a chemical genetic-hit compound, specifically induces mislocalization of both soluble and membrane-associated vacuolar markers in plants and yeast.</p>Fórmula:C26H19NO6Pureza:98%Cor e Forma:SolidPeso molecular:441.43MDK7677
CAS:<p>MDK7677 is a selective inhibitor of cathepsin B endopeptidase and exopeptidase activities.</p>Fórmula:C12H10N4O3Cor e Forma:SolidPeso molecular:258.23Furaprofen
CAS:<p>Furaprofen is an HCV inhibitor with anti-inflammatory activity that inhibits carrageenan-induced paw edema in rats.</p>Fórmula:C17H14O3Pureza:98.49% - 99.52%Cor e Forma:SolidPeso molecular:266.29GEMSA
CAS:<p>GEMSA is a potent inhibitor of enkephalin convertase ( K i =8.8 nM) with analgesic effect[1].</p>Fórmula:C7H13N3O4SCor e Forma:SolidPeso molecular:235.26WAY-151693
CAS:<p>WAY-151693 is an inhibitor of human collagenase-3 (MMP-13).</p>Fórmula:C21H22ClN3O5SCor e Forma:SolidPeso molecular:463.93
