Proteases/Proteassoma
Os inibidores de proteases e proteassomas são compostos que bloqueiam a atividade das proteases e do proteassoma, que estão envolvidos na degradação e renovação de proteínas. Esses inibidores são vitais para estudar a regulação da homeostase de proteínas, controle do ciclo celular e apoptose. Inibidores de proteases e proteassomas também são utilizados no tratamento de doenças como o câncer, onde a degradação anormal de proteínas desempenha um papel na progressão da doença. Ao inibir proteases ou o proteassoma, esses compostos podem induzir a morte celular em células cancerígenas e são ferramentas essenciais tanto na pesquisa básica quanto no desenvolvimento terapêutico. Na CymitQuimica, oferecemos uma ampla gama de inibidores de proteases e proteassomas de alta qualidade para apoiar sua pesquisa em bioquímica, biologia celular e desenvolvimento de medicamentos.
Subcategorias de "Proteases/Proteassoma"
- Acetil- CoA Carboxilase(34 produtos)
- Cisteína Protease(96 produtos)
- DPP-4(20 produtos)
- Glutaminase(40 produtos)
- HIV Protease(449 produtos)
- PAI-1(25 produtos)
- Inibidores de Protease(50 produtos)
- Receptor activado por protease(53 produtos)
- Proteassoma(94 produtos)
- Protease serina(50 produtos)
- p97(14 produtos)
Exibir 3 mais subcategorias
Foram encontrados 1044 produtos de "Proteases/Proteassoma"
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AK 275
CAS:<p>AK 275 is a calpain inhibitor that prevents degradation of cytoskeletal and myelin proteins in spinal cord in vitro.</p>Fórmula:C20H31N3O4Cor e Forma:SolidPeso molecular:377.48AZD-9684
CAS:<p>AZD-9684, a carboxypeptidase U inhibitor, is used potentially for the prevention of thrombosis.</p>Fórmula:C10H14N2O2SCor e Forma:SolidPeso molecular:226.3ITX-4520
CAS:<p>ITX-4520 novel highly potent, orally bioavailable inhibitor of hepatitis C virus (HCV) entry.</p>Fórmula:C24H23F2N3OSCor e Forma:SolidPeso molecular:439.52Epostatin
CAS:<p>Epostatin is a new dipeptidyl peptidase II (DPP-II, EC 3.4.14.2) inhibitor.</p>Fórmula:C23H33N3O5Pureza:98%Cor e Forma:SolidPeso molecular:431.53L 722151
CAS:<p>L 722151 is an FXIIIa inhibitor.</p>Fórmula:C8H9ClN2O5S3Pureza:98%Cor e Forma:SolidPeso molecular:344.82Chymase-IN-1
CAS:<p>Chymase-IN-1 is a selective, orally active inhibitor of human mast cell chymase (IC50: 29 nM).</p>Fórmula:C20H15ClNO4PSPureza:99.17%Cor e Forma:SolidPeso molecular:431.83GSK-2793660
CAS:<p>GSK-2793660, an oral, irreversible CTSC inhibitor, aids bronchiectasis research.</p>Fórmula:C20H27N3O3Pureza:98%Cor e Forma:SolidPeso molecular:357.45ADAMTS-5-IN-2
CAS:<p>ADAMTS-5-IN-2 is a potent inhibitor of ADAMTS-5, exhibiting an IC50 of 0.71 µM, and holds potential for osteoarthritis research.</p>Fórmula:C17H15N3OSCor e Forma:SolidPeso molecular:309.39Safironil
CAS:<p>Safironil, a novel antifibrotic, competitively inhibits collagen synthesis and modulates fibrosis, impacting type I/III collagen levels.</p>Fórmula:C15H23N3O4Pureza:99.83%Cor e Forma:SolidPeso molecular:309.36TNK2-IN-1
CAS:<p>TNK2-IN-1 is a TNK2 inhibitor (IC50: 224 nM) that can be used in cancer research.</p>Fórmula:C23H24N6O2Cor e Forma:SolidPeso molecular:416.48SP-Chymostatin B
CAS:<p>SP-Chymostatin B inhibits proteases like chymotrypsin and papain; less effective on human elastase; works at 100-200 μg/ml.</p>Fórmula:C30H41N7O6Pureza:98%Cor e Forma:SolidPeso molecular:595.69K 579
CAS:<p>K 579 is a dipeptidyl peptidase IV inhibitor.</p>Fórmula:C17H24N6OPureza:98%Cor e Forma:SolidPeso molecular:328.41Antiviral agent 30
CAS:<p>Antiviral Agent 30 (Example 118) is an active compound against HCV and RSV with an inhibitory concentration (IC 50) of greater than 25μM [1].</p>Fórmula:C21H32N2O3SCor e Forma:SolidPeso molecular:392.56PTIQ
CAS:<p>MMP-3 expression inhibitor</p>Fórmula:C13H17NO3Pureza:98%Cor e Forma:SolidPeso molecular:235.28BAY-678 racemate
CAS:<p>BAY-678 racemate: orally active, selective cell-permeable HNE inhibitor with IC50 of 20 nM.</p>Fórmula:C20H15F3N4O2Pureza:98%Cor e Forma:SolidPeso molecular:400.35WNK-IN-7
CAS:<p>WNK-IN-7 is a potent and selective WNK1 kinase inhibitor.</p>Fórmula:C26H29N3OPureza:98%Cor e Forma:SolidPeso molecular:399.53ABT-770
CAS:<p>ABT-770: an orally potent and selective MMP inhibitor, shown to reduce tumor growth in animal models.</p>Fórmula:C22H22F3N3O6Cor e Forma:SolidPeso molecular:481.42BR351 precursor
CAS:<p>BR351 precursor is a precursor of BR351. BR351 is a brain penetrant MMP inhibitor (IC50s: 4, 2, 11, 50 nM for MMP2, MMP8, MMP9 and MMP13).</p>Fórmula:C27H32N2O8S2Pureza:98%Cor e Forma:SolidPeso molecular:576.68CA 074
CAS:<p>CA 074 is a potent inhibitor of cathepsin B with a Ki value of 2 to 5 nM.CA 074 inhibits ischemic hippocampal neuronal death in primates and attenuates</p>Fórmula:C18H29N3O6Pureza:97.80%Cor e Forma:SolidPeso molecular:383.44XMU-MP-2
CAS:<p>XMU-MP-2 is a potent and selective protease inhibitor with anticancer activity that inhibits the growth of oncogenic BRK-driven tumors in a mouse xenograft</p>Fórmula:C32H33F3N8O2Pureza:99.29%Cor e Forma:SolidPeso molecular:618.65RS-104966
CAS:<p>RS-104966 is an inhibitor of collagenase that acts by inducing the conformational change in the side-chains of the S1 pocket of MMP-1.</p>Fórmula:C19H21NO6SPureza:98%Cor e Forma:SolidPeso molecular:391.44Ono-3307 mesylate
CAS:<p>no-3307 mesylate is a protease inhibitor that inhibits a variety of proteases and may be used to study pancreatitis.</p>Fórmula:C15H18N4O7S2Pureza:97.60% - 98.16%Cor e Forma:SolidPeso molecular:430.46Thrombin inhibitor 6
CAS:<p>Thrombin Inhibitor 6, with an IC 50 of 1 nM, acts as a potent anticoagulant by inhibiting thrombin.</p>Fórmula:C18H19ClN4O2SCor e Forma:SolidPeso molecular:390.892',5-Difluoro-2'-deoxycytidine
CAS:<p>2',5-Difluoro-2'-deoxycytidine has potent anti-HCV activity and toxicity to rRNA.</p>Fórmula:C9H11F2N3O4Pureza:98%Cor e Forma:SolidPeso molecular:263.2Gü1303
CAS:<p>Gü1303 is a highly potent and reversible inhibitor of Cathepsin K (CatK), with a Ki value of 0.91 nM for mature CatK (mCatK).</p>Fórmula:C20H22N4O3Cor e Forma:SolidPeso molecular:366.41LY 135305
CAS:<p>LY 135305 is a inhibition of spontaneous metastasis.</p>Fórmula:C19H20ClNPureza:98%Cor e Forma:SolidPeso molecular:297.82Batimastat sodium salt
CAS:<p>Batimastat (BB-94) sodium salt is a broad-spectrum MMP inhibitor (IC50s: 3, 4, 4, 6, and 20 nM for MMP-1, MMP-2, MMP-9, MMP-7, and MMP-3).</p>Fórmula:C23H31N3NaO4S2Pureza:98%Cor e Forma:SolidPeso molecular:500.63HCV-IN-37
CAS:<p>HCV-IN-37: potent HCV inhibitor, stable in rat plasma post-oral dose (15 mg/kg), blocks virus entry phase.</p>Fórmula:C31H35F2N5Cor e Forma:SolidPeso molecular:515.64BrBzGCp2
CAS:<p>BrBzGCp2 (p BrBzGSH(Cp)2) is a GLO1 inhibitor with antitumor activities, relieving anxiety, and is useful in researching neurological disorders.</p>Fórmula:C27H38BrN3O6SPureza:98.68% - 98.68%Cor e Forma:SolidPeso molecular:612.58ACH-806
CAS:<p>ACH-806 is an NS4A antagonist. It can inhibit Hepatitis C Virus (HCV) replication with an EC50 of 14 nM.</p>Fórmula:C19H20F3N3O2SPureza:98%Cor e Forma:SolidPeso molecular:411.44Tyrosinase-IN-1
CAS:<p>Tyrosinase-IN-1: potent inhibitor for skin-whitening & food preservation with uses in cosmetics & medicine.</p>Fórmula:C10H9N3O2S2Cor e Forma:SolidPeso molecular:267.33KIN1400
CAS:<p>KIN1400 activates IRF3, boosts antiviral immunity, stimulates IFNbeta, and inhibits WNV, DV, and HCV.</p>Fórmula:C24H17F2N3O2SPureza:98%Cor e Forma:SolidPeso molecular:449.47MK-2048
CAS:<p>MK-2048 is a potent inhibitor of integrase (IN) and INR263K with IC50 of 2.6 nM and 1.5 nM, respectively.</p>Fórmula:C21H21ClFN5O4Pureza:98%Cor e Forma:SolidPeso molecular:461.87OM-189
CAS:<p>OM-189 is a selective inhibitor of synthetic thrombin.</p>Fórmula:C24H36N6O3SPureza:98%Cor e Forma:SolidPeso molecular:488.65Adafosbuvir PM
CAS:<p>Adafosbuvir PM (AL-335 PM) is a small molecule NS5B inhibitor that can be used to study chronic hepatitis C.</p>Fórmula:C10H13FN2O6Pureza:97.08%Cor e Forma:SolidPeso molecular:276.22FK-448 Free base
CAS:<p>FK-448 Free base is an effective and specific inhibitor of chymotrypsin, with an IC50 of 720 nM.</p>Fórmula:C25H30N2O3Pureza:98%Cor e Forma:SolidPeso molecular:406.52BMS-986094
CAS:<p>INX 08189 is an RNA-directed RNA polymerase (NS5B) inhibitor.</p>Fórmula:C30H39N6O9PCor e Forma:SolidPeso molecular:658.64BR351
CAS:<p>BR351 is a brain penetrant MMP inhibitor (IC50s: 4, 2, 11, 50 nM for MMP2, MMP8, MMP9 and MMP13).</p>Fórmula:C20H25FN2O5SPureza:98%Cor e Forma:SolidPeso molecular:424.49LB-30057
CAS:<p>LB-30057 is used as an oral thrombin inhibitor.</p>Fórmula:C26H31N5O3SPureza:98%Cor e Forma:SolidPeso molecular:493.62U 27391
CAS:<p>U 27391 is a metalloproteinase inhibitor. It acts by inhibits the action of human recombinant interleukin-1beta and glycosaminoglycan synthesis.</p>Fórmula:C23H36N4O5Pureza:98%Cor e Forma:SolidPeso molecular:448.56MDL-101146, (S)-
CAS:<p>MDL-101146, (S)- is an effective orally active inhibitor of human neutrophil elastase.</p>Fórmula:C29H37F5N4O6Pureza:98%Cor e Forma:SolidPeso molecular:632.62Gemigliptin Tartrate(911637-19-9 free base)
CAS:<p>Gemigliptin Tartrate (LC15-0444 tartrate) is a highly selective, reversible and competitive inhibitor of dipeptidyl peptidase-4 (DPP-4).</p>Fórmula:C22H25F8N5O8Pureza:>99.99%Cor e Forma:SolidPeso molecular:639.45Cysteine protease inhibitor-2
CAS:<p>Cysteine protease inhibitor from US20070032499A1; halts DCT116 at 6.5μM, PC3 at 4.4μM.</p>Fórmula:C13H5N5OPureza:98%Cor e Forma:SolidPeso molecular:247.21ZD8321
CAS:<p>ZD8321 is an effective inhibitor of human Neutrophil elastase (Ki: 13±1.7 nM).</p>Fórmula:C18H28F3N3O5Pureza:98%Cor e Forma:SolidPeso molecular:423.43Proteasome-IN-1
CAS:<p>Proteasome-IN-1 is an inhibitor of proteasome.</p>Fórmula:C42H35N5O3Pureza:98%Cor e Forma:SolidPeso molecular:657.76Tanomastat
CAS:<p>Tanomastat is an orally bioavailable and non-peptidic biphenyl matrix metalloproteinases inhibitor.</p>Fórmula:C23H19ClO3SPureza:98%Cor e Forma:SolidPeso molecular:410.91IMB-26
CAS:<p>IMB-26 is an HCV inhibitor (EC50: 2.1 μM) and has shown potent anti-HCV effects.</p>Fórmula:C20H23BrN2O6Cor e Forma:SolidPeso molecular:467.31TAPI-1
CAS:<p>TAPI1 (TAPI) , an ADAM17/TACE inhibitor, inhibits shedding of cytokine receptors.</p>Fórmula:C26H37N5O5Pureza:≥95%Cor e Forma:SolidPeso molecular:499.6Desethyl KBT-3022
CAS:<p>Desethyl KBT-3022 is an active metabolite of the antiplatelet compound KBT-3022.</p>Fórmula:C23H20N2O4SPureza:98%Cor e Forma:SolidPeso molecular:420.48ZYZ-488
CAS:<p>ZYZ-488 is an Apoptosis protease activating factor-1 (Apaf-1) inhibitor, which suppresses the activation of procaspase-9 and procaspase-3.</p>Fórmula:C20H29N3O11Pureza:99.04%Cor e Forma:SolidPeso molecular:487.46
