Proteases/Proteassoma
Os inibidores de proteases e proteassomas são compostos que bloqueiam a atividade das proteases e do proteassoma, que estão envolvidos na degradação e renovação de proteínas. Esses inibidores são vitais para estudar a regulação da homeostase de proteínas, controle do ciclo celular e apoptose. Inibidores de proteases e proteassomas também são utilizados no tratamento de doenças como o câncer, onde a degradação anormal de proteínas desempenha um papel na progressão da doença. Ao inibir proteases ou o proteassoma, esses compostos podem induzir a morte celular em células cancerígenas e são ferramentas essenciais tanto na pesquisa básica quanto no desenvolvimento terapêutico. Na CymitQuimica, oferecemos uma ampla gama de inibidores de proteases e proteassomas de alta qualidade para apoiar sua pesquisa em bioquímica, biologia celular e desenvolvimento de medicamentos.
Subcategorias de "Proteases/Proteassoma"
- Acetil- CoA Carboxilase(35 produtos)
- Cisteína Protease(96 produtos)
- DPP-4(20 produtos)
- Glutaminase(40 produtos)
- HIV Protease(450 produtos)
- PAI-1(25 produtos)
- Inibidores de Protease(50 produtos)
- Receptor activado por protease(53 produtos)
- Proteassoma(94 produtos)
- Protease serina(50 produtos)
- p97(14 produtos)
Exibir 3 mais subcategorias
Foram encontrados 1044 produtos de "Proteases/Proteassoma"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
H-Pro-Lys-OH TFA
<p>H-Pro-Lys-OH TFA is a dipeptide composed of proline and lysine, serving as a substrate for imino dipeptidase (prolinase). Additionally, it can be utilized in peptide synthesis.</p>Fórmula:C13H22F3N3O5Cor e Forma:SolidPeso molecular:357.33PD-166793
CAS:<p>PD-166793 is an MMP inhibitor with inhibitory effects on MMP-2, MMP-3 and MMP-13.PD-166793 improves myocardial ischemia in a rat heart failure model.</p>Fórmula:C17H18BrNO4SPureza:99.86%Cor e Forma:SolidPeso molecular:412.3Saxagliptin hydrochloride
CAS:<p>Saxagliptin: oral DPP-4 inhibitor, enhances incretins, manages type 2 diabetes by reducing glucose levels.</p>Fórmula:C18H26ClN3O2Cor e Forma:SolidPeso molecular:351.87Alogliptin (13CD3)
CAS:<p>Alogliptin (SYR-322) 13CD3 is the deuterium-labeled Alogliptin. Alogliptin is a selective inhibitor of DPP-4.</p>Fórmula:C18H21N5O2Pureza:98%Cor e Forma:SolidPeso molecular:343.4Pentosan Polysulfate Sodium (W/W 43%)
CAS:<p>Pentosan Polysulfate Sodium: anti-HIV, anti-inflammatory, aids cartilage, treats interstitial cystitis.</p>Pureza:98%Cor e Forma:SolidPeso molecular:N/ADabigatran ethyl ester
CAS:<p>Dabigatran ethyl ester (Dabigatran (ethyl ester)) is an emerging oral anticoagulant and it also is a direct inhibitor of thrombin activity.</p>Fórmula:C27H29N7O3Pureza:99.98%Cor e Forma:SolidPeso molecular:499.56Chlorcyclizine
CAS:<p>CHLORCYCLIZINE is a histamine H1 antagonist and a potent hepatitis C virus (HCV) entry inhibitor.</p>Fórmula:C18H21ClN2Pureza:98.75%Cor e Forma:SolidPeso molecular:300.83Coblopasvir
CAS:<p>Coblopasvir is a pan-genotypic non-structural protein 5A (NS5A) inhibitor. It can be used to study chronic hepatitis C virus infection.</p>Fórmula:C41H50N8O8Pureza:99.33%Cor e Forma:SolidPeso molecular:782.88Raltegravir
CAS:<p>Raltegravir (MK-0518) is a pyrrolidinone derivative and HIV INTEGRASE INHIBITOR that is used in combination with other ANTI-HIV AGENTS for the treatment of HIV</p>Fórmula:C20H21FN6O5Pureza:99.86% - >99.99%Cor e Forma:SolidPeso molecular:444.42KGP94
CAS:<p>KGP94 is a potent, selective, and competitive inhibitor of the lysosomal endopeptidase enzyme.</p>Fórmula:C14H12BrN3OSPureza:99.6%Cor e Forma:SolidPeso molecular:350.23Tris(4-aminophenyl)methane
CAS:<p>Tris(4-aminophenyl)methane (Leucopararosaniline), a triphenylmethane dye, is a weak HCV helicase inhibitor.</p>Fórmula:C19H19N3Pureza:95.73%Cor e Forma:Beige Solid CrystallinePeso molecular:289.37Anagliptin hydrochloride
CAS:<p>Anagliptin (SK-0403) hydrochloride: potent, selective oral DPP-4 inhibitor; IC50: DPP-4 3.8 nM, DPP-8 68 nM, DPP-9 60 nM.</p>Fórmula:C19H26ClN7O2Cor e Forma:SolidPeso molecular:419.91Efegatran
CAS:<p>Efegatran is a hematologic agent and platelet aggregation inhibitor.</p>Fórmula:C21H32N6O3Cor e Forma:SolidPeso molecular:416.52Raltegravir potassium
CAS:<p>Raltegravir potassium (MK 0518 potassium salt) salt(MK0518 potassium salt) is a potent integrase (IN) inhibitor, used to treat HIV infection.</p>Fórmula:C20H20FN6O5·KPureza:98% - 99.55%Cor e Forma:Off-White SolidPeso molecular:482.51KKI-5 acetate(97145-43-2 free base)
<p>KKI-5 acetate: Serine protease inhibitor, targets kallikrein/plasmin, potential anticancer and angioedema therapy.</p>Fórmula:C37H59N11O11Pureza:99.44%Cor e Forma:SolidPeso molecular:833.95JNJ0966
CAS:<p>JNJ0966 is a highly selective MMP-9 zymogen inhibitor (IC50: 440 nM).</p>Fórmula:C16H16N4O2S2Pureza:99.46% - 99.62%Cor e Forma:SolidPeso molecular:360.452-CHLOROMETHYL-1,1-DIOXO-1,2-DIHYDRO-1λ*6*-BENZO[D]ISOTHIAZOL-3-ONE
CAS:<p>2-CHLOROMETHYL-1,1-DIOXO-1,2-DIHYDRO-1LAMBDA*6*-BENZO[D]ISOTHIAZOL-3-ONE targets the Neutrophil elastase (human).</p>Fórmula:C8H6ClNO3SPureza:97.28%Cor e Forma:SolidPeso molecular:231.66Delavirdine mesylate
CAS:<p>Delavirdine mesylate (BHAP-U 90152 (mesylate)) is a non-nucleoside reverse transcriptase inhibitor (NNRTI).</p>Fórmula:C23H32N6O6S2Pureza:99.99%Cor e Forma:Light Brown SolidPeso molecular:552.67ML281
CAS:<p>ML281 is a potent and selective STK33 inhibitor with IC50 of 14 nM.</p>Fórmula:C22H19N3O2SPureza:99.12% - 99.87%Cor e Forma:SolidPeso molecular:389.47Ximelagatran
CAS:<p>Ximelagatran, oral direct thrombin inhibitor, transforms to active melagatran in body.</p>Fórmula:C24H35N5O5Pureza:95.48% - 99.60%Cor e Forma:SolidPeso molecular:473.57Dolutegravir
CAS:<p>Dolutegravir (GSK1349572), HIV integrase inhibitor with IC50 of 2.7 nM, partly effective against some raltegravir-resistant HIV strains.</p>Fórmula:C20H19F2N3O5Pureza:98.97% - 99.75%Cor e Forma:White To Pale Yellow SolidPeso molecular:419.38Fostemsavir
CAS:<p>Fostemsavir (BMS-663068) is an HIV-1 attachment inhibitor in development for the treatment of HIV-1 infection.</p>Fórmula:C25H26N7O8PPureza:98.95%Cor e Forma:SolidPeso molecular:583.49Obefazimod
CAS:<p>Obefazimod (ABX-464) is a potent anti-HIV agent. ABX464 inhibits HIV-1 replication in stimulated peripheral blood mononuclear cells (PBMCs).</p>Fórmula:C16H10ClF3N2OPureza:99.86%Cor e Forma:SolidPeso molecular:338.71Ditiocarb sodium
CAS:Ditiocarb sodium (Sodium diethyldithiocarbamate) (sodium diethiocarbamate) is a copper reagent, which reacts with Cu2 + solution to form a complex and improvesFórmula:C5H10NNaS2Pureza:98.04%Cor e Forma:White Solid CrystallinePeso molecular:171.26Ivachtin
CAS:<p>Ivachtin (Caspase-3 Inhibitor VII) is a nonpeptide, noncompetitive and reversibl caspase-3 inhibitor(IC50 = 23 nM) and is a modest inhibitor of the remaining</p>Fórmula:C20H21N3O7SPureza:99.74%Cor e Forma:SolidPeso molecular:447.46Avatrombopag
CAS:<p>Avatrombopag (YM477) is a new oral thrombopoietin (TPO) receptor agonist, activating TPO receptor and increasing megakaryocytic proliferation/differentiation</p>Fórmula:C29H34Cl2N6O3S2Pureza:99.01% - 99.63%Cor e Forma:SolidPeso molecular:649.65S 3304
CAS:<p>S 3304 is a novel matrix metalloproteinases inhibitor which is specific for MMP-2 and MMP-9.</p>Fórmula:C24H20N2O4S2Pureza:98.09%Cor e Forma:SolidPeso molecular:464.56Velpatasvir
CAS:<p>Velpatasvir (GS-5816), also known as GS-5816, is a potent and selective Hepatitis C virus NS5A inhibitor.</p>Fórmula:C49H54N8O8Pureza:99.17% - 99.83%Cor e Forma:SolidPeso molecular:883Bemnifosbuvir hemisulfate
CAS:<p>Bemnifosbuvir hemisulfate (AT-527) is a potent inhibitor of HCV virus replication.</p>Fórmula:C48H68F2N14O18P2SPureza:99.98%Cor e Forma:SolidPeso molecular:1261.15Lusutrombopag
CAS:<p>Lusutrombopag (Mulpleta) is an orally bioavailable, small molecule thrombopoietin (TPO) receptor agonist for chronic liver disease (CLD) patients with</p>Fórmula:C29H32Cl2N2O5SPureza:99.96%Cor e Forma:SolidPeso molecular:591.55Paritaprevir
CAS:<p>Paritaprevir (ABT450) 是一种非结构蛋白 3/4A 蛋白酶抑制剂，对 HCV 1a 和 HCV 1b 的 EC50 值分别为 1 和 0.21 nM。它也是SARS-CoV 3CLpro 的抑制剂，IC50为 1.31 μM。</p>Fórmula:C40H43N7O7SPureza:99.72%Cor e Forma:SolidPeso molecular:765.88RN-18
CAS:<p>RN-18 is an inhibitor of HIV-1 viral infectivity factor (IC50: 6 μM in nonpermissive H9 cells).</p>Fórmula:C20H16N2O4SPureza:97.21% - 98.39%Cor e Forma:SolidPeso molecular:380.42Boc-Asp(OMe)-fluoromethyl ketone
CAS:<p>Boc-Asp(OMe)-FMK is a broad-spectrum caspase inhibitor that blocks Fas-mediated processes without affecting IL-8 chemotaxis.</p>Fórmula:C11H18FNO5Pureza:≥98%Cor e Forma:SolidPeso molecular:263.26Etravirine
CAS:<p>Etravirine (R165335) is a diarylpyrimidine non-nucleoside reverse transcriptase inhibitor.</p>Fórmula:C20H15BrN6OPureza:97.61% - 99.74%Cor e Forma:White To Off-White SolidPeso molecular:435.284-Butylresorcinol
CAS:4-Butylresorcinol (Butylresorcinol) is a potent inhibitor of tyrosinase(IC50 : 11.27 μM), and is used in cosmetics as a depigmenting agent.Fórmula:C10H14O2Pureza:99.48% - ≥95%Cor e Forma:Light Beige Solid PowderPeso molecular:166.22TAPI-1 trifluoroacetate (163847-77-6(free base))
TAPI-1 is an ADAM17/TACE inhibitor, which blocks shedding of cytokine receptors.Fórmula:C28H38F3N5O7Pureza:98.06%Cor e Forma:SolidPeso molecular:613.62Grazoprevir
CAS:<p>Grazoprevir (MK-5172) is a protease inhibitor targeting hepatitis C virus NS3/4A used for treating chronic HCV genotypes 1 or 4 infections. Cost-effective and quality-assured.</p>Fórmula:C38H50N6O9SPureza:99.36% - >99.99%Cor e Forma:SolidPeso molecular:766.9Dabigatran Etexilate Mesylate
CAS:<p>Dabigatran Etexilate Mesylate (BIBR 1048MS) is the orally active prodrug of dabigatran. Dabigatran is a reversible and selective, direct thrombin inhibitor.</p>Fórmula:C34H41N7O5·CH4O3SPureza:99.91%Cor e Forma:SolidPeso molecular:723.84LY 3000328
CAS:<p>LY 3000328 (Cathepsin S inhibitor) is a selective inhibitor of cathepsin S.Cost-effective and quality-assured.</p>Fórmula:C25H29FN4O5Pureza:97.83% - 99.54%Cor e Forma:SolidPeso molecular:484.52Peptide T acetate(106362-32-7 free base)
<p>Peptide T acetate is an octapeptide from the V2 region of HIV-1 gp120.</p>Fórmula:C37H59N9O18Pureza:99.47%Cor e Forma:SolidPeso molecular:917.91(S,S)-TAPI-1
CAS:<p>"(S,S)-TAPI-1, an isomer of TAPI-1, inhibits MMPs and TACE (ADAM17), reducing cell surface protein shedding."</p>Fórmula:C26H37N5O5Cor e Forma:SolidPeso molecular:499.6Darunavir
CAS:<p>Darunavir (TMC114) is an HIV PROTEASE INHIBITOR that is used in the treatment of AIDS and HIV INFECTIONS.</p>Fórmula:C27H37N3O7SPureza:99.67% - 99.76%Cor e Forma:White Amorphous SolidPeso molecular:547.66Coblopasvir dihydrochloride
CAS:<p>Coblopasvir dihydrochloride can be used to study chronic HCV infection and is a pan-genotypic nonstructural protein 5A (NS5A) inhibitor.</p>Fórmula:C41H52Cl2N8O8Pureza:99.33%Cor e Forma:SolidPeso molecular:855.81TCH-165
CAS:<p>TCH-165 boosts 20S proteasome levels, enhancing IDP breakdown.</p>Fórmula:C39H37N3O3Pureza:98.2% - 98.75%Cor e Forma:SolidPeso molecular:595.73Letermovir
CAS:<p>Letermovir (AIC246) (AIC246) is a novel anti-CMV compound (EC50: about 5 nM in fibroblast cells). It targets the pUL56 subunit of the viral terminase complex.</p>Fórmula:C29H28F4N4O4Pureza:99.85% - 99.87%Cor e Forma:SolidPeso molecular:572.55Daclatasvir
CAS:<p>Daclatasvir (EBP 883/BMS-790052) is a potent HCV NS5A inhibitor with EC50 9-50 pM across various genotypes. Phase 3.</p>Fórmula:C40H50N8O6Pureza:99.81%Cor e Forma:SolidPeso molecular:738.88CA-074 methyl ester
CAS:<p>CA-074 methyl ester (Cathepsin B Inhibitor IV) is a selective inhibitor of Cathepsin B (IC50=36.3 nM). neuroprotective effect. High-Quality, Low-Cost!</p>Fórmula:C19H31N3O6Pureza:97.26% - 99.58%Cor e Forma:SolidPeso molecular:397.47XMD8-87
CAS:<p>XMD8-87 (ACK1-B19), a TNK2 inhibitor, strongly blocks TNK2 phosphorylation and mutations in tumors.</p>Fórmula:C24H27N7O2Pureza:98.05% - 99.89%Cor e Forma:SolidPeso molecular:445.52Bemnifosbuvir
CAS:<p>Bemnifosbuvir (AT-511) is a novel phosphoramidate prodrug of 2'-fluoro-2'-C-methylguanosine-5'-monophosphate that has potent in vitro activity against HCV.</p>Fórmula:C24H33FN7O7PPureza:99.35% - 99.54%Cor e Forma:SolidPeso molecular:581.53Daclatasvir dihydrochloride
CAS:<p>Daclatasvir dihydrochloride is an oral antiviral that treats chronic hepatitis C by inhibiting HCV's NS5A; rare liver enzyme elevation, seldom causes jaundice.</p>Fórmula:C40H52Cl2N8O6Pureza:99.67%Cor e Forma:SolidPeso molecular:811.8
![2-CHLOROMETHYL-1,1-DIOXO-1,2-DIHYDRO-1λ*6*-BENZO[D]ISOTHIAZOL-3-ONE](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FT8602.webp&w=3840&q=75)
