Autofagia
Os inibidores da autofagia têm como alvo o processo celular de autofagia, que envolve a degradação e reciclagem de componentes celulares através dos lisossomas. A autofagia é um mecanismo crítico para a manutenção da homeostase celular, mas sua desregulação está implicada em várias doenças, incluindo câncer, neurodegeneração e infecções. Os inibidores da autofagia podem bloquear este processo, tornando-os ferramentas valiosas para estudar o papel da autofagia nas doenças e desenvolver estratégias terapêuticas. Na CymitQuimica, oferecemos inibidores da autofagia para apoiar sua pesquisa em biologia celular, oncologia e doenças neurodegenerativas.
Foram encontrados 1424 produtos de "Autofagia"
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Naringin
CAS:<p>Naringin: flavanone glycoside with blood lipid-reducing, antioxidant, anticancer properties, inhibits cytochrome P450.</p>Fórmula:C27H32O14Pureza:99.23%Cor e Forma:Beige Creamish Powder Solid Solid Particulate/PowderPeso molecular:580.53Deferoxamine Mesylate
CAS:<p>Deferoxamine Mesylate (DFOM) is an iron chelator and iron death inhibitor.</p>Fórmula:C26H52N6O11SPureza:94.68% - 99.8%Cor e Forma:SolidPeso molecular:656.79Oxaliplatin
CAS:<p>Oxaliplatin (L-OHP) is a DNA alkylating agent, an inhibitor of DNA synthesis.</p>Fórmula:C8H14N2O4PtPureza:97% - 99.93%Cor e Forma:SolidPeso molecular:397.29Sunitinib Malate
CAS:<p>Sunitinib Malate (Sunitinib) is an indolinone-based tyrosine kinase inhibitor.</p>Fórmula:C26H33FN4O7Pureza:98% - 99.26%Cor e Forma:SolidPeso molecular:532.56Pemetrexed
CAS:<p>Pemetrexed (LY-231514 Disodium Hydrate), a guanine-derived antineoplastic agent, binds to and inhibits the enzyme thymidylate synthase (TS).</p>Fórmula:C20H21N5O6Pureza:98.1% - 99.92%Cor e Forma:Similar To White PowderPeso molecular:427.41ZX-29
CAS:<p>ZX-29: Strong ALK inhibitor; IC50 - ALK 2.1 nM, L1196M 1.3 nM, G1202R 3.9 nM; triggers autophagy; anti-cancer.</p>Fórmula:C23H28ClN7O3SPureza:98.32%Cor e Forma:SolidPeso molecular:518.03Doxazosin mesylate
CAS:<p>Doxazosin mesylate (UK 33274 mesylate)(UK 33274) is a quinazoline-derivative. It is a selectively antagonizes postsynaptic α1-adrenergic receptors.</p>Fórmula:C24H29N5O8SPureza:99.92%Cor e Forma:White To Off-White Crystalline PowderPeso molecular:547.58Memantine hydrochloride
CAS:<p>Memantine hydrochloride (Memantine HCl) is an AMANTADINE derivative that has some dopaminergic effects.</p>Fórmula:C12H22ClNPureza:99.56% - 99.96%Cor e Forma:Crystalline SolidPeso molecular:215.76TTNPB
CAS:<p>TTNPB (Ro 13-7410,AGN-191183), a potent RAR agonist, inhibits binding of [3H]tRA of human RARα (IC50: 5.1 nM), β (IC50: 4.5 nM), and γ (IC50: 9.3 nM),</p>Fórmula:C24H28O2Pureza:99.55%Cor e Forma:White SolidPeso molecular:348.48Monacolin J
CAS:<p>Monacolin J (Antibiotic MB 530A) is a cholesterol biosynthesis inhibitor.</p>Fórmula:C19H28O4Pureza:98.06%Cor e Forma:SolidPeso molecular:320.423,3'-Diindolylmethane
CAS:<p>3,3'-Diindolylmethane (DIM), a small molecule compound, is a proposed Y preventive agent.</p>Fórmula:C17H14N2Pureza:99.09%Cor e Forma:SolidPeso molecular:246.31Sorafenib tosylate
CAS:<p>Sorafenib tosylate (Bay 43-9006) is a potent multikinase inhibitor (IC50s: 6/20/22 nM for Raf-1/VEGFR-3/B-Raf).</p>Fórmula:C21H16ClF3N4O3·C7H8O3SPureza:99.24% - 99.94%Cor e Forma:White To Off-White Crystalline PowderPeso molecular:637.03Rupatadine Fumarate
CAS:<p>Rupatadine Fumarate (Rinialer) (UR-12592 Fumarate) is a potent dual PAF/H1 antagonist with Ki of 0.55/0.1 uM.</p>Fórmula:C26H26ClN3·C4H4O4Pureza:99.86%Cor e Forma:White Or Almost-White PowderPeso molecular:532.03Tepotinib
CAS:<p>Tepotinib (EMD-1214063) is a selective, orally, and ATP-competitive c-MET tyrosine kinase inhibitor. Tepotinib has antitumor effect. Cost-effective and quality-assured.</p>Fórmula:C29H28N6O2Pureza:98% - 99.91%Cor e Forma:SolidPeso molecular:492.57Pictilisib dimethanesulfonate
CAS:<p>Pictilisib dimethanesulfonate (GDC-0941 2 MeSO3H salt) is a potent inhibitor of PI3Kα/δ with IC50 of 3 nM, with modest selectivity against p110β (11-fold) and</p>Fórmula:C25H35N7O9S4Pureza:99.63%Cor e Forma:SolidPeso molecular:705.85Thioridazine hydrochloride
CAS:<p>Thioridazine hydrochloride (Mellaril) , an antipsychotic drug, is used in the therapy of psychosis and schizophrenia and shows serotonin antagonism or D4</p>Fórmula:C21H27ClN2S2Pureza:99.55% - 99.957%Cor e Forma:White To Off-White SolidPeso molecular:407.04Dasatinib
CAS:<p>Dasatinib (BMS-354825) is a tyrosine kinase inhibitor that inhibits Src and Bcr-Abl (Ki=16/30 pM) and is orally active and ATP-competitive.</p>Fórmula:C22H26ClN7O2SPureza:99.59% - 99.86%Cor e Forma:Pale-Yellow SolidPeso molecular:488.01Vancomycin hydrochloride
CAS:<p>Vancomycin hydrochloride (Vancomycin HCl) targets peptidoglycan in bacterial cell wall synthesis. High-Quality, Low-Cost!</p>Fórmula:C66H76Cl3N9O24Pureza:97.20% - 99.19%Cor e Forma:Off White PowderPeso molecular:1485.71Telmisartan
CAS:<p>Telmisartan (BIBR 277) is an Angiotensin 2 Receptor Blocker. The mechanism of action of telmisartan is as an Angiotensin 2 Receptor Antagonist.</p>Fórmula:C33H30N4O2Pureza:99.88% - 99.97%Cor e Forma:White Or Off White Crystalline PowderPeso molecular:514.62Pemetrexed disodium
CAS:<p>Pemetrexed disodium treats lung cancer/mesothelioma; may cause moderate serum enzyme elevation, rarely acute liver injury.</p>Fórmula:C20H19N5Na2O6Pureza:99.29% - 99.49%Cor e Forma:Crystalline SolidPeso molecular:471.37
