GPCR/Proteína-G
Os inibidores de GPCR/proteínas G são compostos que têm como alvo os receptores acoplados a proteínas G (GPCRs) e as proteínas G associadas, que desempenham papéis críticos na transmissão de sinais do exterior para o interior das células. Esses inibidores são essenciais para estudar as vias de sinalização mediadas por GPCRs, que estão envolvidas em numerosos processos fisiológicos, incluindo percepção sensorial, resposta imunológica e neurotransmissão. Os inibidores de GPCR também são importantes no desenvolvimento de medicamentos, pois muitos agentes terapêuticos têm como alvo esses receptores. Na CymitQuimica, oferecemos uma ampla gama de inibidores de GPCR/proteínas G de alta qualidade para apoiar sua pesquisa em farmacologia, biologia celular e áreas afins.
Subcategorias de "GPCR/Proteína-G"
- Receptor 5-HT(942 produtos)
- Receptor de adenosina(242 produtos)
- Receptor adrenérgico(2.949 produtos)
- Receptor de Bombesina(30 produtos)
- Receptor de Bradicinina(59 produtos)
- CXCR(149 produtos)
- CaSR(32 produtos)
- Receptor de Canabinóides(195 produtos)
- Receptor de Dopamina(410 produtos)
- Receptor Endotelina(75 produtos)
- Receptor GNRH(73 produtos)
- GPCR19(31 produtos)
- GRK(32 produtos)
- GTPase(21 produtos)
- Receptor Glucagon(166 produtos)
- Hedgehog/Smoothened(45 produtos)
- Receptor de Histamina(359 produtos)
- Receptor LPA(21 produtos)
- Receptor de Melatonina(24 produtos)
- Receptor OX(40 produtos)
- Receptor opioide(298 produtos)
- PAFR(11 produtos)
- PKA(49 produtos)
- Receptor S1P(17 produtos)
- SGLT(30 produtos)
- Receptor Sigma(46 produtos)
Exibir 18 mais subcategorias
Foram encontrados 5378 produtos de "GPCR/Proteína-G"
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EP3 antagonist 4
CAS:<p>EP3 antagonist 4: hEP inhibitor, Ki = 2 nM, low clearance, high oral AUC, good bioavailability in rats, potential for diabetes research.</p>Fórmula:C22H20Cl3FN4O3S2Pureza:98%Cor e Forma:SoildPeso molecular:577.91RS 18286
CAS:<p>RS 18286 is a LHRH antagonist.</p>Fórmula:C74H101Cl2N17O14Cor e Forma:SolidPeso molecular:1523.6Leukotriene B4 Ethanolamide
CAS:<p>LTB4 binds to BLT1 (high affinity) and BLT2. LTB4-EA, a metabolite, is a stronger BLT1 antagonist, suggesting anti-inflammatory properties.</p>Fórmula:C22H37NO4Cor e Forma:SolidPeso molecular:379.5412-Methyl-N,N-dimethyltryptamine
CAS:<p>2-Methyl-N,N-dimethyltryptamine (2,N,N-TMT, compound 15) exhibits binding affinity for the serotonin (5-HT) receptor, with a pA2 value of 6.04. It plays a significant role in neurological disease research.</p>Fórmula:C13H18N2Cor e Forma:SolidPeso molecular:202.3Kisspeptin-54(human)
CAS:Endogenous ligand for KISS1 receptor; Ki values: rat 1.80 nM, human 1.45 nM. Inhibits tumor spread, stimulates gonadotropin release.Fórmula:C258H401N79O78Pureza:98%Cor e Forma:SolidPeso molecular:5857.49Abediterol napadisylate
CAS:<p>Abediterol napadisylate is a novel long-acting β2-agonist in persistent asthma that is efficacy, safe, and tolerable.</p>Fórmula:C60H68F4N4O14S2Pureza:98%Cor e Forma:SolidPeso molecular:1209.32RF9 acetate
<p>RF9 acetate is an effective and selective antagonist of Neuropeptide FF receptor with Ki values of 58 and 75 nM for hNPFF1R and hNPFF2R, respectively.</p>Fórmula:C28H42N6O5Pureza:99.77%Cor e Forma:SolidPeso molecular:542.67Nebokitug
<p>Nebokitug is a humanized IgG1κ antibody targeting CCL24, with HumanIgG1kappa, Isotype Control serving as its corresponding isotype control.</p>Cor e Forma:Odour LiquidNPS ALX Compound 4a hydrochloride(1:1)
<p>NPS ALX Compound 4a hydrochloride(1:1) is a potent and selective 5-hydroxytryptamine6 (5-HT6) receptor antagonist, with an IC50 of 7.2 nM and a Ki of 0.2 nM.</p>Fórmula:C25H26ClN3O2SPureza:99.84%Cor e Forma:SoildPeso molecular:468.01Spns2-IN-2
<p>Spns2-IN-2 (compound 3a) is an inhibitor of SPNS2.</p>Fórmula:C22H30ClN3O2Cor e Forma:SolidPeso molecular:403.95BIIE-0246
CAS:BIIE-0246 is a selective NPY2R antagonist, IC50=15 nM at the rat [125I]PYY3-36 site, reduces NPY-stimulated expression of p-AKT S473 and P-p44/42 MAPK.Fórmula:C49H57N11O6Pureza:98%Cor e Forma:SolidPeso molecular:896.05MRS 4062 triethylammonium salt
CAS:<p>MRS 4062 triethylammonium salt is a selective P2Y4 receptor agonist (EC50 values are 23, 640, and 740 nM for hP2Y4, hP2Y2 and hP2Y6 respectively).</p>Fórmula:C42H86N7O15P3Cor e Forma:SolidPeso molecular:1022.105Vapiprost
CAS:<p>Vapiprost is an antagonist of the thromboxane receptor and a prostaglandin receptor.</p>Fórmula:C30H39NO4Pureza:98%Cor e Forma:SolidPeso molecular:477.64S1R agonist 2
CAS:<p>S1R agonist 2 is a selective S1R agonist with a Ki of 88 nM for S2R and 1.1 nM for S1R and is protective against ROS and NMDA-induced neurotoxicity.</p>Fórmula:C21H27NOPureza:98.85%Cor e Forma:SolidPeso molecular:309.45Plozalizumab
CAS:<p>Plozalizumab (MLN-1202) is a humanized selective and potent anti-CCR2 antibody.Plozalizumab has antitumor activity.Plozalizumab is used in the study of</p>Pureza:96.4%Cor e Forma:LiquidPeso molecular:146.02 kDaOrexin A (human, rat, mouse)
CAS:Orexin A, a 33 AA neuropeptide in humans, rats, mice, influences various processes, studied in pancreatic function and as an OX1R antagonist.Fórmula:C152H243N47O44S4Pureza:98%Cor e Forma:SolidPeso molecular:3561.1SB 699551
CAS:<p>SB 699551 is a selective 5-HT5A antagonist (Ki=6.31 nM) that enhances 5-HT neuronal function. It inhibits SERT (Ki=25.12 nM),inhibit breast cancer.</p>Fórmula:C34H45N3OPureza:99.83%Peso molecular:511.74Dopamine D2 receptor agonist-2
CAS:<p>Dopamine D2 receptor agonist-2 (Dopamine D2 Receptor) is a ligand targeting the dopamine D2 receptor.</p>Fórmula:C25H31Cl2N5OSPureza:98.93%Cor e Forma:SoildPeso molecular:520.52U-46619 serinol amide
<p>U-46619 serinol amide is a derivative of U-46619, acting as a stable analog of Thromboxane A2 (TXA2). It effectively functions as a TXA2 agonist, capable of inducing platelet shape change and aggregation.</p>Fórmula:C24H41NO5Cor e Forma:SolidPeso molecular:423.29847[Phe8Ψ(CH-NH)-Arg9]-Bradykinin
CAS:<p>Selective bradykinin B2 receptor agonist that is resistant to carboxypeptidase cleavage.</p>Fórmula:C50H75N15O10Pureza:98%Cor e Forma:SolidPeso molecular:1046.23PSB-SB-1203
CAS:<p>PSB-SB-1203 (Compound 25b) is a dual CB1/CB2 ligand that blocks the CB1 receptor and activates the CB2 receptor with a CB1 Ki of 0.244 μM, a CB2 Ki of 0.210 μM, and an EC50 of 0.054 μM. It shows potential for research in obesity and cancer.</p>Fórmula:C25H30O4Cor e Forma:SolidPeso molecular:394.5Kassinin
CAS:<p>Kassinin is a peptide derived from the Kassina frog. It belongs to tachykinin family of neuropeptides.</p>Fórmula:C59H95N15O18SPureza:98%Cor e Forma:SolidPeso molecular:1334.54Jatrorrhizine hydroxide
CAS:<p>Jatrorrhizine hydroxide: alkaloid from Coptis chinensis; neuroprotective, antimicrobial, antiplasmodial, antioxidant; AChE inhibitor, affects 5-HT/NE uptake.</p>Fórmula:C20H21NO5Cor e Forma:SolidPeso molecular:355.38LRGILS-NH2
CAS:<p>LRGILS-NH2, reverse sequence of SLIGRL-NH2, is a control peptide for PAR2, affecting gut transit.</p>Fórmula:C29H56N10O7Pureza:98%Cor e Forma:SolidPeso molecular:656.82CGRP antagonist 6
<p>CGRP Antagonist 6 (Compound 23) is a potent CGRP receptor antagonist (Ki: 0.84 nM). It is utilized in the study of migraines.</p>Cor e Forma:Odour SolidIRL-1038
CAS:<p>ETB endothelin receptor antagonist</p>Fórmula:C68H92N14O15S2Pureza:98%Cor e Forma:SolidPeso molecular:1409.67A-286501
CAS:<p>A-286501: Oral adenosine kinase inhibitor, IC50=0.47 nM, reduces pain via non-opioid, non-NSAID ADO receptors.</p>Fórmula:C11H14BrN5O2Pureza:98%Cor e Forma:SolidPeso molecular:328.1716-phenoxy tetranor Prostaglandin F2α isopropyl ester
CAS:<p>Prostaglandin F2α (PGF2α) drives luteolysis and smooth muscle contraction by activating the FP receptor.</p>Fórmula:C25H36O6Cor e Forma:SolidPeso molecular:432.557CAY10509
CAS:<p>CAY10509 is a PGF2α analogue and acts as an FP receptor inhibitor with an IC50 of 30 nM. It shows potential for use in studying the physiological regulatory mechanisms related to prostaglandins.</p>Fórmula:C23H35FO5SCor e Forma:SolidPeso molecular:442.58Afubiata
CAS:<p>ADB-FUBIATA is a synthetic cannabinoid studied for its metabolic profile, along with AFUBIATA, CH-FUBIATA, and CH-PIATA. This in vitro analysis by Watanabe S, et al., examines these compounds, as published in "Arch Toxicol," 2023 Dec;97(12):3085-3094.</p>Fórmula:C27H29FN2OCor e Forma:SolidPeso molecular:416.53Des-Arg9-[Leu8]-Bradykinin acetate
CAS:<p>Des-Arg9-[Leu8]-Bradykinin acetate is a potent antagonist of the bradykinin receptor 1 (B1R), utilized in renal fibrosis research [1].</p>Fórmula:C43H67N11O12Pureza:98%Cor e Forma:SolidPeso molecular:930.065-HT6R antagonist 1
<p>Compound 8 (5-HT6R antagonist 1), a 5-HT6R antagonist (K i : 5 nM), not only demonstrates inhibition of platelet aggregation and excellent metabolic stability</p>Fórmula:C17H22F2N6OPureza:98%Cor e Forma:SolidPeso molecular:364.39Luteinizing Hormone Releasing Hormone (LH-RH), salmon
CAS:LH-RH: a hypothalamus-made pituitary hormone, key in reproductive control.Fórmula:C60H73N15O13Pureza:98%Cor e Forma:SolidPeso molecular:1212.31LE 300
CAS:<p>LE 300 represents a structurally novel type of antagonists acting preferentially at the dopamine D(1)/D(5)receptors and the serotonin 5-HT(2A)receptor.</p>Fórmula:C20H22N2Pureza:97.91% - 98.79%Cor e Forma:SolidPeso molecular:290.4TRPV1/CB2 agonist 1
<p>TRPV1/CB2 agonist 1 (compound 41) is a dual agonist targeting hTRPV1 and CB2 receptors, with an EC50 value of 26.8 μM for hTRPV1. It is applicable in research related to the nervous system.</p>Cor e Forma:Odour SolidRXFP3/4 agonist 1
CAS:<p>RXFP3/4 agonist 1 is a relaxin family peptide 3/4 receptor (RXFP3/4) agonist(EC50s of 82/2 nM, respectivley).</p>Fórmula:C20H22ClN5OPureza:98%Cor e Forma:SolidPeso molecular:383.88GLP-1R agonist 20
<p>GLP-1R agonist 20 (Compound I-132) is an agonist of the glucagon-like peptide-1 receptor (GLP-1 receptor), with an EC50 value of 0.0162 nM.</p>Fórmula:C31H30Cl2F2N4O5Peso molecular:646.15613Cinnamtannin A2
CAS:<p>Cinnamtannin A2, a tetrameric procyanidin, boosts GLP-1, insulin, CRH expression, and has antioxidant, anti-diabetic, nephroprotective properties.</p>Fórmula:C60H50O24Cor e Forma:SolidPeso molecular:1155.02Sar-[D-Phe8]-des-Arg9-Bradykinin
CAS:<p>Potent bradykinin B1 agonist, EC50 = 9.02 nM, enzyme resistant, induces hypotension and angiogenesis.</p>Fórmula:C47H66N12O11Pureza:98%Cor e Forma:SolidPeso molecular:975.11Tiaprost
CAS:Tiaprost is a analog of prostaglandin F2α .Fórmula:C20H28O6SPureza:98%Cor e Forma:SolidPeso molecular:396.54-(2-chloro-4-methoxy-5-methylphenyl)-N-[(1A)-2-cyclopropyl-1-(3-fluoro-4-methylphenyl)ethyl]-5-methyl-N-(2-propyn-1-yl)-2-thiazolamine
CAS:<p>4-(2-chloro-4-methoxy-5-methylphenyl)-N-[(1A)-2-cyclopropyl-1-(3-fluoro-4-methylphenyl)ethyl]-5-methyl-N-(2-propyn-1-yl)-2-thiazolamine is an enantiomeric</p>Fórmula:C27H28ClFN2OSPureza:99.02%Cor e Forma:SoildPeso molecular:483.04Apelin-36(rat, mouse)
CAS:Endogenous APJ agonist from adipocytes; binds APJ tightly, inhibits cAMP, regulates heart function and fluid balance, blocks some HIV strains.Fórmula:C185H304N68O43SPureza:98%Cor e Forma:SolidPeso molecular:4200.93DOAM
CAS:<p>DOAM is an antagonist of the 5-HT2 receptor.</p>Fórmula:C16H27NO2Cor e Forma:SolidPeso molecular:265.39CCK Octapeptide, non-sulfated acetate
<p>CCK Octapeptide, non-sulfated acetate is a synthetic desulfated peptide of cholecystokinin.</p>Fórmula:C51H66N10O15S2Pureza:98.9700%Cor e Forma:SolidPeso molecular:1123.26GLP-1R agonist 14
CAS:<p>GLP-1R agonist 14, also known as Compound 14, is a potent agonist of the GLP-1 receptor, demonstrating an EC50 range of 0-20 nM against human GLP-1 [1].</p>Fórmula:C45H42F2N10O5Cor e Forma:SolidPeso molecular:840.88REGN-7544
<p>REGN-7544 is a humanised monoclonal antibody targeting NPR1, which blocks and inhibits NPR1 to increase blood pressure, hypotensione.</p>Pureza:95%Cor e Forma:Odour LiquidSerazapine
CAS:<p>Serazapine is a highly specific serotonin (5-HT2) binding inhibitor with anxiolytic activity for the treatment of anxiety disorders.</p>Fórmula:C22H23N3O2Pureza:98.71% - 99.57%Cor e Forma:SolidPeso molecular:361.44Naratriptan D3 Hydrochloride
CAS:Naratriptan D3 Hydrochloride is the deuterium labeled Naratriptan, is a selective agonist of 5-HT1 receptor subtype.Fórmula:C17H26ClN3O2SPureza:98%Cor e Forma:SolidPeso molecular:374.94palm11-PrRP31
<p>Palm11-PrRP31 is a lipid-modified analog of the endogenous appetite-suppressing neuropeptide (PrRP). It functions as a potent dual agonist for GPR10 (EC50 = 39 pM) and NPFF-R2. By mimicking the natural activity of PrRP, palm11-PrRP31 binds to these receptors to reduce food intake. It has potential applications as an anti-obesity agent and is useful in studying neuropeptide and receptor interactions.</p>Fórmula:C181H289N55O46SPeso molecular:4001.16865ACTH (11-24)
CAS:<p>ACTH (11-24) is an adrenocorticotrophin fragment, stimulates cortisol, and antagonizes ACTH (1-39)/(1-10) in adrenal cells.</p>Fórmula:C77H134N24O16Pureza:98%Cor e Forma:SolidPeso molecular:1652.04Eledoisin Related Peptide
CAS:<p>Eledoisin Related Peptide (Eledoisin RP) is a tachykinin receptor ligand.</p>Fórmula:C34H58N8O6SPureza:98%Cor e Forma:SolidPeso molecular:706.94NPFF2-R ligand 1
<p>NPFF2-R ligand 1 (Compound 16a) is an NPFF2-R ligand with Ki values of 228 nM for NPFF1-R and 27 nM for NPFF2-R, and can be utilized in research on central nervous system-related disorders.</p>Fórmula:C32H41N3OPeso molecular:483.32496Triazolomethylindole-3-acetic acid
CAS:<p>Triazolomethylindole-3-acetic acid is a metabolite of Rizatriptan, which acts as an agonist for the serotonin (5-HT) receptor subtypes 5-HT1B and 5-HT1D.</p>Fórmula:C13H12N4O2Cor e Forma:SolidPeso molecular:256.26MM 54
CAS:Potent apelin receptor antagonist (Ki=82 nM, IC50=93 nM), counters [Pyr1]-Apelin-13, inhibits glioblastoma growth in mice.Fórmula:C70H121N29O15S4Pureza:98%Cor e Forma:SolidPeso molecular:1737.15Brexpiprazole S-oxide
CAS:<p>Brexpiprazole S-oxide is the main metabolite of Brexpiprazole, a human 5-HT1A and dopamine receptor partial agonist (Ki: 0.12, 0.3 nM).</p>Fórmula:C25H27N3O3SPureza:98%Cor e Forma:SolidPeso molecular:449.57Adrenomedullin (AM) (22-52), human TFA
<p>Adrenomedullin (AM) human (22-52) is a truncated NH2 TFA-modified adrenal medullary receptor antagonist.</p>Fórmula:C161H253N46F3O50Pureza:98%Cor e Forma:SolidPeso molecular:3690.06Xanthine amine congener dihydrochloride
CAS:<p>XAC dihydrochloride is an Adenosine A1 and A2 receptor antagonist with IC50s of 1.8 nM and 114 nM, also a mouse convulsant.</p>Fórmula:C21H30Cl2N6O4Cor e Forma:SolidPeso molecular:501.41Succinate/succinate receptor antagonist 1
CAS:<p>Potent succinate receptor antagonist with IC50 of 20 μM; blocks gingival succinate signaling, may treat periodontal disease.</p>Fórmula:C17H15N3OPureza:99.53%Cor e Forma:SoildPeso molecular:277.32HAEGTFTSDVS acetate
<p>HAEGTFTSDVS acetate is the first N-terminal 1-11 residues of GLP-1 which stimulates insulin secretion from pancreatic β-cells.</p>Fórmula:C50H75N13O22Pureza:97.47%Cor e Forma:SolidPeso molecular:1210.2Uroguanylin (human) TFA
<p>Uroguanylin (human) (TFA) is the natural ligand for the guanylate cyclase C (GCC) receptor expressed in metastatic colorectal cancer tumors. In animal models of human colon cancer, Uroguanylin (human) (TFA) demonstrates antitumor activity.</p>Cor e Forma:Odour Solid(+)-Cloprostenol
CAS:<p>(+)-Cloprostenol is a analogue of prostaglandin F2α (PGF2α), and is selective prostaglandin receptor agonistic.</p>Fórmula:C22H29ClO6Pureza:98%Cor e Forma:SolidPeso molecular:424.92Pancreatic polypeptide TFA
<p>Pancreatic polypeptide TFA acts as a neuropeptide Y (NPY) Y4/Y5 receptor agonist.</p>Cor e Forma:Odour SolidMK-7246 S enantiomer
MK-7246 S enantiomer is a potent and selective CRTH2 antagonist.Fórmula:C21H21FN2O4SPureza:98%Cor e Forma:SolidPeso molecular:416.47Peptide C105Y TFA
Peptide C105Y TFA is a cell-penetrating peptide synthesized based on the amino acid sequence of residues 359-374 of α1-antitrypsin. It enhances the gene expression of DNA nanoparticles.Fórmula:C97H148N20O23S·xC2HF3O2Dulaglutide
CAS:<p>Dulaglutide (LY2189265) is a GLP-1 receptor agonist for studying type 2 diabetes mellitus (T2DM).</p>Cor e Forma:SolidP2Y6R antagonist 1
<p>P2Y6R antagonist 1 (compound 5ab) is a selective, orally active antagonist of P2Y6R, featuring an IC50 value of 19.6 nM. This compound also exhibits anti-inflammatory properties.</p>Cor e Forma:Odour Solid(±)5(6)-EET
CAS:<p>5(6)-EET is a fully racemic version of the enantiomeric forms biosynthesized from arachidonic acid by cytochrome P450 enzymes.</p>Fórmula:C20H32O3Cor e Forma:SolidPeso molecular:320.473HDAC6-IN-49
<p>HDAC6-IN-49 (Compound 3) is an inhibitor of HDAC, with IC50 values of 0.012 and 0.735 µM against HDAC6 and HDAC1, respectively. Additionally, it inhibits MAO-B, cholinesterase (ChE), histamine receptor (H3R), and serotonin 6 receptor (5-HT6R). HDAC6-IN-49 exhibits neuroprotective effects in SH-SY5Y cells and enhances cognitive functions and motor abilities in fruit fly models of Parkinson's disease and C. elegans models of Alzheimer's disease.</p>Cor e Forma:Odour Solid17-phenyl trinor Prostaglandin E2 ethyl amide
CAS:<p>17-phenyl trinor PGE2 ethyl amide, an EP1/EP3 agonist (Ki: 14-54 nM), enhances lipid solubility and tissue uptake, is a potent antifertility agent.</p>Fórmula:C25H35NO4Cor e Forma:SolidPeso molecular:413.55Adrenocorticotropic Hormone (ACTH) (1-39), rat
CAS:ACTH (1-39), rat: potent MC2 agonist, forms fragments in vitro, isolated by HPLC, characterized by amino acids and NH2-terminus.Fórmula:C210H315N57O57SPureza:98%Cor e Forma:SolidPeso molecular:4582.23Palmitoyl tetrapeptide-20 TFA
Palmitoyl tetrapeptide-20 (PTP20) TFA is a biomimetic peptide and acts as an agonist of α-MSH. It protects follicular melanocytes by boosting catalase expression and activating melanogenesis.Fórmula:C38H70N6O8·xC2HF3O2A6770
CAS:<p>A6770 inhibits S1P lyase, causing [3H]dhS1P build-up in IT-79MTNC3 cells (EC50 <0.01 μM); less effective with vitamin B6 (EC50 <100 μM).</p>Fórmula:C6H8N2O2Cor e Forma:SolidPeso molecular:140.142(Ala13)-Apelin-13
CAS:(Ala13)-Apelin-13 is a useful organic compound for research related to life sciences. The catalog number is T35374 and the CAS number is 568565-11-7.Fórmula:C63H107N23O16SPureza:98%Cor e Forma:SolidPeso molecular:1474.75Cortistatin 14, human, rat acetate
Cortistatin 14, human, rat acetate is a neuropeptide having structural similarity to somatostatin-14 and shows anticonvulsive, neuroprotective effects andFórmula:C80H112N18O19S2Pureza:97.86%Cor e Forma:SolidPeso molecular:1693.985-HT2C agonist-4
CAS:<p>Compound 3i, a 5-HT2C agonist-4, acts as an agonist for the 5-HT2C receptor with an EC50 of 5.7 nM. It is capable of reducing locomotor activity in zebrafish larvae.</p>Fórmula:C24H25N5OCor e Forma:SolidPeso molecular:399.49Tirzepatide hydrochloride
Tirzepatide HCl is a dual GIP and GLP-1 receptor agonist.Fórmula:C225H349N48O68ClPureza:98%Cor e Forma:SolidPeso molecular:4849.91Dipentylone hydrochloride
CAS:<p>Dipentylone hydrochloride (Bk-dmbdp HCl) is a psychoactive synthetic cathinone and sympathomimetic stimulant. Its inhibitory activity towards the dopamine transporter (IC50=0.233µM) is tenfold higher than that towards NET and SERT, inhibiting dopamine uptake and stimulating locomotor activity in mice.</p>Fórmula:C14H20ClNO3Pureza:99.94%Cor e Forma:SolidPeso molecular:285.77Haloperidol D4
CAS:<p>Haloperidol D4 is deuterium-labeled haloperidol.</p>Fórmula:C21H23ClFNO2Pureza:98%Cor e Forma:SolidPeso molecular:379.89Relaxin H3 (human) TFA
Relaxin H3 (human) (TFA) is a relaxin peptide that exerts antifibrotic effects through the RXFP1 receptor.Fórmula:C237H374N70O69S6·xC2HF3O2VIP36
<p>VIP36 is an agonist of the cannabinoid type 1 receptor (CB1) with analgesic properties. It reduces the recruitment of inhibitory proteins, thereby exerting its pain-relieving effects, and is applicable in research related to chronic pain.</p>Fórmula:C27H35FN6O4Cor e Forma:SolidPeso molecular:526.603Jmv 176
CAS:<p>Jmv 176 is a CCK agonist when first given and becomes a cholecystokinin antagonist after 3-4 hours.</p>Fórmula:C53H70N8O15SPureza:98%Cor e Forma:SolidPeso molecular:1091.24GRL018-21
<p>GRL018-21 is a potent, highly selective inhibitor of G protein-coupled receptor kinase 5 (GRK5), exhibiting an IC50 of 10 nM [1].</p>Cor e Forma:Odour SolidDonitriptan hydrochloride
CAS:<p>Donitriptan hydrochloride (Donitriptan monohydrochloride) is a potent, high efficacy agonist of 5-HT1B/1D receptors with pKis of 9.4 and 9.3, respectively</p>Fórmula:C23H26ClN5O2Pureza:99.8% - 99.86%Cor e Forma:SolidPeso molecular:439.94INCB 3284 dimesylate
CAS:INCB 3284 dimesylate: oral CCR2 antagonist, blocks MCP-1/hCCR2 binding (IC50: 3.7 nM), potential in acute liver failure research.Fórmula:C28H39F3N4O10S2Pureza:98%Cor e Forma:SolidPeso molecular:712.76Imelciment
CAS:<p>Imelciment (REGN-9035) is a humanised monoclonal antibody targeting NPR1, which can be used for research into heart failure.</p>Pureza:95%Cor e Forma:SoildBAM(8-22)
CAS:<p>Potent MRGPRX1 agonist peptide; first found in bovine adrenal glands. Non-opioid, lacking met-enkephalin motif. EC50: 8-150 nM.</p>Fórmula:C91H127N25O23SPureza:98%Cor e Forma:SolidPeso molecular:1971.22Cannabidiolic acid methyl ester
CAS:<p>Cannabidiolic acid methyl ester (HU-580) is an orally active analogue of cannabidiolic acid. It enhances the activation of 5-HT1A receptors and increases the expression of c-Fos and NeuN in specific hypothalamic nuclei in rats. Cannabidiolic acid methyl ester exhibits anti-nausea, anxiolytic, and anti-nociceptive effects.</p>Fórmula:C23H32O4Cor e Forma:SolidPeso molecular:372.5Ivabradine-d3 hydrochloride
CAS:<p>Ivabradine HCl: novel If blocker, IC50 2.9 μM, slows heart rate; D3 version is deuterium labeled.</p>Fórmula:C27H37ClN2O5Pureza:98%Cor e Forma:SolidPeso molecular:508.0712(S)-HpEPE
CAS:<p>12(S)-HpEPE, a fatty acid created by 12-lipoxygenase on EPA, has unclear biological activities but may resemble 12(S)-HpETE.</p>Fórmula:C20H30O4Cor e Forma:SolidPeso molecular:334.456Poly-D-lysine hydrobromide (MW 1000-5000)
<p>Poly-D-lysine hydrobromide (PDLHB) (MW 1000-5000) is a synthetically produced polymeric substrate widely used in neural cell culture. Additionally, Poly-D-lysine hydrobromide acts as a CaSR agonist peptide.</p>Cor e Forma:Odour SolidEsmolol acid hydrochloride
CAS:<p>Esmolol acid (ASL-8123) hydrochloride is a mild antagonist of β-adrenergic receptors. It inhibits the heart rate and diastolic pressure responses induced by Isoproterenol in a dose-dependent manner and is applicable for renal failure research.</p>Fórmula:C15H24ClNO4Cor e Forma:SolidPeso molecular:317.81Somatostatin 1-28 acetate
<p>Somatostatin 1-28 acetate circulates in human plasma.</p>Pureza:99.22%Cor e Forma:SoildEfranarelaxin alfa
CAS:<p>Efranarelaxin alfa is an agonist of the relaxin receptor. It shows potential for research in cardiovascular diseases and tissue repair.</p>Cor e Forma:Liquid11-deoxy Prostaglandin E2
CAS:<p>11-deoxy PGE2 is a synthetic PGE2 analog, a potent bronchoconstrictor, 5-30x stronger than PGF2α on human respiratory muscles.</p>Fórmula:C20H32O4Cor e Forma:SolidPeso molecular:336.47Poly-D-lysine hydrobromide (MW 150000-300000)
<p>Poly-D-lysine hydrobromide (MW 150000-300000) enhances neural cell adhesion in culture and acts as a calcium-sensing receptor agonist peptide in research.</p>Cor e Forma:Odour SolidFR 113680
CAS:FR 113680 is a tripeptide substance P antagonist with NK1 receptor selectivity.Fórmula:C35H39N5O6Pureza:98%Cor e Forma:SolidPeso molecular:625.726Obestatin(rat)
CAS:<p>Endogenous peptide that suppresses food intake and body weight-gain</p>Fórmula:C114H174N34O31Pureza:98%Cor e Forma:SolidPeso molecular:2516.81Levocarnitine propionate hydrochloride
CAS:<p>Levocarnitine propionate hydrochloride (ST-261) is used for the treatment of the deterioration of renal function, congestive heart failure, and other diseases.</p>Fórmula:C10H20ClNO4Pureza:90% - 99.77%Cor e Forma:SolidPeso molecular:253.72Cyclosomatostatin Acetate
<p>Cyclosomatostatin Acetate is an effective antagonist of the somatostatin receptor.Cyclosomatostatin Acetate inhibits SSTR1 signaling and decreases cell</p>Fórmula:C46H61N7O8Pureza:98.83%Cor e Forma:SolidPeso molecular:840.02SB 216641
CAS:<p>SB 216641 is a 5-HT (1B/1D) antagonist with anxiolytic activity for the study of anxiety disorders and depression.</p>Fórmula:C28H30N4O4Pureza:98.09%Cor e Forma:SolidPeso molecular:486.56
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