GPCR/Proteína-G
Os inibidores de GPCR/proteínas G são compostos que têm como alvo os receptores acoplados a proteínas G (GPCRs) e as proteínas G associadas, que desempenham papéis críticos na transmissão de sinais do exterior para o interior das células. Esses inibidores são essenciais para estudar as vias de sinalização mediadas por GPCRs, que estão envolvidas em numerosos processos fisiológicos, incluindo percepção sensorial, resposta imunológica e neurotransmissão. Os inibidores de GPCR também são importantes no desenvolvimento de medicamentos, pois muitos agentes terapêuticos têm como alvo esses receptores. Na CymitQuimica, oferecemos uma ampla gama de inibidores de GPCR/proteínas G de alta qualidade para apoiar sua pesquisa em farmacologia, biologia celular e áreas afins.
Subcategorias de "GPCR/Proteína-G"
- Receptor 5-HT(942 produtos)
- Receptor de adenosina(242 produtos)
- Receptor adrenérgico(2.949 produtos)
- Receptor de Bombesina(30 produtos)
- Receptor de Bradicinina(59 produtos)
- CXCR(149 produtos)
- CaSR(32 produtos)
- Receptor de Canabinóides(195 produtos)
- Receptor de Dopamina(410 produtos)
- Receptor Endotelina(75 produtos)
- Receptor GNRH(73 produtos)
- GPCR19(31 produtos)
- GRK(32 produtos)
- GTPase(21 produtos)
- Receptor Glucagon(166 produtos)
- Hedgehog/Smoothened(45 produtos)
- Receptor de Histamina(359 produtos)
- Receptor LPA(21 produtos)
- Receptor de Melatonina(24 produtos)
- Receptor OX(40 produtos)
- Receptor opioide(298 produtos)
- PAFR(11 produtos)
- PKA(49 produtos)
- Receptor S1P(17 produtos)
- SGLT(30 produtos)
- Receptor Sigma(46 produtos)
Exibir 18 mais subcategorias
Foram encontrados 5378 produtos de "GPCR/Proteína-G"
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Fenoldopam
CAS:<p>Fenoldopam is a selective D1-like dopamine receptor partial agonist (EC50 = 57 nM).</p>Fórmula:C16H16ClNO3Pureza:98%Cor e Forma:SolidPeso molecular:305.76Apadenoson TFA
<p>Apadenoson TFA is a potent adenosine A2A receptor (A2AR) agonist that can be used to improve survival in patients infected with SARS.</p>Fórmula:C25H31F3N6O8Pureza:98.08%Cor e Forma:SoildPeso molecular:600.55Teprotumumab
CAS:<p>Teprotumumab: human antibody, inhibits IGF-1R, used for thyroid eye diseases.</p>Pureza:SDS-PAGE:95.2%;SEC-HPLC:99.6%Cor e Forma:LiquidPeso molecular:145.62 kDa(R)-(+)-Atenolol
CAS:<p>(R)-(+)-Atenolol ((R)-Atenolol) is a cardioselective beta-1 adrenergic blocker, which properties are similar to propranolol, but without a negative inotropic effect.</p>Fórmula:C14H22N2O3Pureza:98.72%Cor e Forma:SolidPeso molecular:266.34Surfagon
CAS:Surfagon is an effective LHRH agonist.Fórmula:C56H78N16O12Pureza:98%Cor e Forma:SolidPeso molecular:1167.34AL 34662
CAS:<p>AL 34662 is a selective and potent 5-HT2A receptor agonist with IC50s of 0.77 nM and 1.5 nM for rat and human 5-HT2 receptors, respectively.AL 34662 is also a</p>Fórmula:C10H13N3OPureza:99.77%Cor e Forma:SolidPeso molecular:191.23CTP-amiodarone
<p>CTP-amiodarone, a cellular-penetrating conjugate of myocardial cell-targeting peptide and Amiodarone, exhibits anti-arrhythmic activity by blocking Na+, K+, and Ca2+ channels as well as β-adrenergic receptors.</p>Fórmula:C97H131F3I2N20O25S2Cor e Forma:SolidPeso molecular:2352.13Pentagastrin meglumine
CAS:<p>Pentagastrin meglumine is a synthetic pentapeptide that has effects like gastrin when given parenterally.</p>Fórmula:C44H66N8O14SCor e Forma:SolidPeso molecular:963.11Nastorazepide hemicalcium
CAS:<p>Nastorazepide (Z-360) hemicalcium is a selective, orally-administered 1,5-benzodiazepine derivative that functions as a receptor antagonist for gastrin/cholecystokinin 2 (CCK-2), exhibiting potential antitumor activity.</p>Fórmula:C29H36N4O5CaCor e Forma:SolidPeso molecular:540.66EB1002
CAS:<p>EB1002 is a selective NK2R agonist that has demonstrated significant enhancements in the expression levels of genes associated with mitochondrial biogenesis (such as PGC-1α) in obese mice. This suggests that EB1002 promotes energy expenditure by enhancing mitochondrial activity. Additionally, EB1002 has improved insulin sensitivity and glucose-lipid metabolism in mice. Therefore, EB1002 holds potential for research into obesity and type 2 diabetes.</p>Fórmula:C73H124N12O23Cor e Forma:SolidPeso molecular:1537.83ONO-8711
CAS:<p>ONO-8711 is a potent and selective competitive antagonist of EP1 receptor with Kis of 0.6 nM and 1.7 nM for human and mouse EP1, respectively.</p>Fórmula:C22H30ClNO4SCor e Forma:SolidPeso molecular:440PACAP-38 (16-38), human, mouse, rat
CAS:<p>PACAP-38 (16-38), human, mouse, rat demonstrates potent, efficacious, and sustained stimulatory effects on sympathetic neuronal NPY and catecholamine production</p>Fórmula:C123H215N39O28SPureza:98%Cor e Forma:SolidPeso molecular:2720.33Cholic Acid 7-sulfate
CAS:<p>Cholic acid 7-sulfate: a cholic acid metabolite with added sulfate at position 7, increased in feces of male mice with specific diets.</p>Fórmula:C24H40O8SCor e Forma:SolidPeso molecular:488.64d[Leu4,Lys8]-VP
CAS:<p>Vasopressin V1B agonist; Ki: 0.16nM V1B, 64nM oxytocin; weak antidiuretic/vasopressor; minimal oxytocic action.</p>Fórmula:C47H67N11O11S2Pureza:98%Cor e Forma:SolidPeso molecular:1026.2GLP-2(1-33)(human)
CAS:GLP-2(1-33) (human) is an enteroendocrine hormone which stimulates the growth of the intestinal epithelium.Fórmula:C165H254N44O55SPureza:98%Cor e Forma:SolidPeso molecular:3766.19Pancreatic Polypeptide, human
CAS:<p>Endogenous high affinity agonist for human NPY Y4 receptor (Ki = 0.056 nM). Believed to play an important role in the function of the gastrointestinal tract.</p>Fórmula:C185H287N53O54S2Pureza:98%Cor e Forma:SolidPeso molecular:4181.7116-phenoxy tetranor Prostaglandin F2α methyl ester
CAS:<p>Prostaglandin F2α (PGF2α) drives luteolysis and smooth muscle contraction by activating the FP receptor.</p>Fórmula:C23H32O6Cor e Forma:SolidPeso molecular:404.503AMI-193
CAS:<p>AMI-193 (Spiramide) is a selective 5-HT2 & D2 receptor antagonist with antipsychotic properties.</p>Fórmula:C22H26FN3O2Pureza:99.65%Cor e Forma:SolidPeso molecular:383.46Urocortin II, human TFA
<p>hUcn II, a CRF family member, targets CRF2 receptor, has time-linked stress regulation effects, showing mild motor suppression and delayed anxiolytic action.</p>Fórmula:C196H340F3N63O56SPureza:98%Cor e Forma:SolidPeso molecular:4564.3GLP-1R Agonist DMB
CAS:<p>GLP-1R Agonist DMB is an agonist of glucagon-like peptide 1 receptor (GLP-1R; KB = 26.3 nM for the recombinant human receptor).</p>Fórmula:C13H15Cl2N3O2SPureza:99.52%Cor e Forma:SolidPeso molecular:348.25Crustacean Cardioactive Peptide (CCAP)
CAS:Crustacean Cardioactive Peptide (CCAP) is a conserved modified cyclic nonapeptide primary structure of PFCNAFTGC-NH2, a disulfide bridge between Cys3 and Cys9.Fórmula:C42H58N10O12S2Pureza:95.40%Cor e Forma:SolidPeso molecular:959.1GLP-1R agonist 27
<p>GLP-1R agonist 27 (compound 21) is a potent and orally active GLP-1R agonist. It enhances the accumulation of cyclic adenosine monophosphate (cAMP), reduces blood glucose levels, and decreases food intake. GLP-1R agonist 27 shows potential for research in obesity and type 2 diabetes mellitus (T2DM).</p>Fórmula:C32H33N5O4SeCor e Forma:SolidPeso molecular:630.6Antisauvagine-30 TFA
<p>aSvg-30 TFA: potent CRF2 receptor antagonist, Kd 1.4 nM (mCRFR2β), 150 nM (CRFR1).</p>Fórmula:C163H275N48F3O49SCor e Forma:SolidPeso molecular:3764.285-OMe-UDP trisodium salt
CAS:<p>Potent P2Y6 agonist</p>Fórmula:C10H16N2O13P2Pureza:98%Cor e Forma:SolidPeso molecular:434.19IRL-1038
CAS:<p>ETB endothelin receptor antagonist</p>Fórmula:C68H92N14O15S2Pureza:98%Cor e Forma:SolidPeso molecular:1409.67tBPC
CAS:<p>Enhances Y4R response to PP, NPY & PYY with EC50 of 0.03, 0.4, 0.5 nM; selective for Y4R over Y1R, Y2R, Y5R.</p>Fórmula:C16H24O2Cor e Forma:SolidPeso molecular:248.36Leukotriene B4 Ethanolamide
CAS:<p>LTB4 binds to BLT1 (high affinity) and BLT2. LTB4-EA, a metabolite, is a stronger BLT1 antagonist, suggesting anti-inflammatory properties.</p>Fórmula:C22H37NO4Cor e Forma:SolidPeso molecular:379.541AB21 HCl
<p>AB21 HCl: σ1 receptor antagonist, Ki 13 nM; less potent at σ2 (102 nM). Reduces mechanical hypersensitivity.</p>Fórmula:C23H29ClN2OPureza:99.91%Cor e Forma:SolidPeso molecular:384.2B7-33
CAS:B7-33 is a single-chain relaxin analog and a selective agonist for relaxin receptor 1 (RXFP1). It binds to RXFP1 and preferentially activates the pERK pathway in cells expressing RXFP1, rather than cAMP. B7-33 serves as an antifibrotic agent and provides cardioprotective effects.Fórmula:C131H229N41O36SCor e Forma:SolidPeso molecular:2986.54LHRH
CAS:<p>Luteinizing hormone-releasing hormone (LHRH) is a neuropeptide produced in the hypothalamus that plays a pivotal role in regulating reproduction and has</p>Fórmula:C55H74N16O14Pureza:98%Cor e Forma:SolidPeso molecular:1183.27Galantide acetate
<p>Galantide acetate, a non-specific galanin receptor antagonist, is a peptide consisting of fragments of galanin and substance P.</p>Fórmula:C106H155N25O28SPureza:97.8% - 97.91%Cor e Forma:SolidPeso molecular:2259.58Des His1, Glu8 Exendin-4
<p>Des His1, Glu8 Exendin-4 is a glucagon-like peptide-1 receptor (GLP1R) antagonist that regulates blood glucose and is used in the study of diabetes and obesity.</p>Fórmula:C179H277N47O59SPureza:99.92%Cor e Forma:SolidPeso molecular:4063.46human GALP (3-32)
<p>Human GALP (3-32) (Galanin-like peptide (3-32)) serves as a high-affinity agonist for galanin receptors GalR1 (IC50 = 33 nM) and GalR2 (IC50 = 15 nM), as</p>Fórmula:C137H213N43O38SPureza:98%Cor e Forma:SolidPeso molecular:3102.495-HT6 agonist 1
Compound 19, a 5-HT6 agonist with an affinity (K i : 5 nM), exhibits antidepressant-like effects and enhances cognitive function while also inhibiting plateletFórmula:C17H22Cl2N6SPureza:98%Cor e Forma:SolidPeso molecular:413.37AB21 oxalate
<p>AB21 oxalate, a potent and selective S1R antagonist, exhibits binding affinities (Kis) of 13 nM and 102 nM for S1R and S2R, respectively.</p>Fórmula:C25H30N2O5Pureza:98%Cor e Forma:SolidPeso molecular:438.52Muscarinic toxin 3
CAS:<p>Muscarinic toxin 3 (MT3), a potent non-competitive antagonist of mAChR and adrenoceptors, exhibits pIC50 values of 6.71 for M1, 8.79 for M4, 8.86 for α1A, 7.57</p>Fórmula:C319H489N89O97S8Pureza:98%Cor e Forma:SolidPeso molecular:7379.35IRAK inhibitor 4 trans
<p>IRAK inhibitor 4 targets and blocks IRAK4 activity; refers to its trans molecular configuration.</p>Fórmula:C33H35F3N6O3Pureza:98%Cor e Forma:SolidPeso molecular:620.66(+)-Dropropizine
CAS:<p>(+)-Dropropizine can inhibit histamine receptor, anti-allergic, and reduce a cough by modulation of neuropeptides involved in the cough reflex.</p>Fórmula:C13H20N2O2Pureza:>99.99%Cor e Forma:White Or Off White Crystalline PowderPeso molecular:236.31PSB-1114 triethylamine
<p>PSB-1114 triethylamine is a potent, enzymatically stable, P2Y2 receptor agonist with a 134 nM EC50, exhibiting greater than 50-fold selectivity over P2Y4 (EC50</p>Fórmula:C10H15F2N3O13P3S·xC6H15NPureza:98%Cor e Forma:Solidα-CGRP (mouse, rat) TFA
<p>α-CGRP (mouse, rat) TFA, a neuropeptide belonging to the calcitonin gene-related peptide (CGRP) family, is predominantly located at neuromuscular junctions and</p>Fórmula:C162H262N50O52S2·C2HF3O2Pureza:98%Cor e Forma:SolidO-Desmethyl Mebeverine alcohol hydrochloride
CAS:<p>O-Desmethyl Mebeverine alcohol HCl, a metabolite of Mebeverine, is a strong α1 inhibitor, relaxing the GI tract.</p>Fórmula:C15H26ClNO2Cor e Forma:SolidPeso molecular:287.83Emoghrelin
CAS:<p>Emoghrelin, extracted from Heshouwu (Polygonum multiflorum), promotes the secretion of growth hormone by activating the ghrelin receptor [1].</p>Fórmula:C24H22O13Pureza:98%Cor e Forma:SolidPeso molecular:518.42JNJ-40929837 succinate
CAS:<p>JNJ-40929837 succinate is a selective, orally active inhibitor of LTA 4 H (leukotriene A 4 hydrolase). This compound effectively inhibits aminopeptidase activity, leading to the accumulation of Pro-Gly-Pro in serum, and can be utilized in asthma research [1].</p>Fórmula:C22H24N4O2S·xC4H6O4Cor e Forma:SolidBIM-23190 hydrochloride
<p>BIM-23190 hydrochloride, somatostatin analog, SSRT2/5 agonist, Ki: 0.34 nM (SSTR2), 11.1 nM (SSTR5). Used in cancer, acromegaly research.</p>Cor e Forma:LiquidHS024 TFA
<p>HS024, a selective MC4 receptor antagonist, exhibits affinity with Ki values of 0.29, 3.29, 5.45, and 18.6 nM for MC4, MC5, MC3, and MC1 receptors, respectively</p>Fórmula:C60H80F3N19O12S2Cor e Forma:SolidPeso molecular:1380.52GLP-1(28-36)amide TFA
<p>GLP-1(28-36)amide TFA, a nonapeptide cleavage product of GLP-1, shows antioxidant properties with anti-diabetic and cardioprotective effects.</p>Fórmula:C56H86F3N15O11Cor e Forma:SolidPeso molecular:1202.37LH-RH (7-10)
CAS:LH-RH (7-10), a tetrapeptide, is a key LHRH degradation product found in macrophages and pneumocytes.Fórmula:C19H36N8O4Cor e Forma:SolidPeso molecular:440.54FFN246
CAS:<p>FFN246, a fluorescent probe, concurrently targets the serotonin transporter (SERT) and vesicular monoamine transporter 2 (VMAT2), exhibiting excitation and</p>Fórmula:C15H13FN2OPureza:98%Cor e Forma:SolidPeso molecular:256.27SAR441255
SAR441255 is a potent unimolecular peptide that acts as a GLP-1/GIP/GCG receptor triagonist, demonstrating balanced activation across all three target receptorsCor e Forma:Odour SolidSubstance P (alligator)
CAS:<p>Substance P from alligator: a neuropeptide with structure Arg-Pro-Arg-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2.</p>Fórmula:C63H98N20O13SCor e Forma:SolidPeso molecular:1375.64Amylin, amide, human TFA
<p>Amylin, a 37-amino acid human hormone, moderates glucose regulation by reducing glucagon, delaying digestion, and increasing satiety.</p>Fórmula:C167H262F3N51O57S2Cor e Forma:SolidPeso molecular:4017.3Pramlintide
CAS:<p>Pramlintide, a polypeptide analog of human amylin, is an antidiabetic agent with antineoplastic properties in colorectal cancer.</p>Cor e Forma:SolidCCZ01048 TFA
CCZ01048 TFA, α-MSH analog, binds MC1R with 0.31 nM affinity, internalizes in melanoma cells, and is stable for melanoma PET imaging.Fórmula:C73H106F3N21O18Cor e Forma:SolidPeso molecular:1622.75(Phe2,Orn8)-Oxytocin acetate
<p>(Phe2,Orn8)-Oxytocin acetate: V1 agonist with EC50 of 280 nM for rabbit epididymis contractility.</p>Fórmula:C44H69N13O13S2Cor e Forma:SolidPeso molecular:1052.23CART(55-102)(rat) TFA
<p>Rat CART(55-102) TFA suppresses appetite, links to leptin/neuropeptide Y, and may induce anxiety/stress.</p>Fórmula:C228H368F3N65O67S7Cor e Forma:SolidPeso molecular:5373.2DOTA-JR11
CAS:<p>DOTA-JR11 is a somatostatin receptor 2 (SSTR2) antagonist that can be radiolabeled with 68Ga.</p>Fórmula:C74H98ClN19O21S2Cor e Forma:SolidPeso molecular:1689.27Neuropeptide SF(mouse,rat) TFA
<p>Neuropeptide SF TFA is a potent agonist for NPFF1 (Ki=48.4 nM) and NPFF2 (Ki=12.1 nM) and enhances ASIC3 current.</p>Fórmula:C42H66F3N13O12Cor e Forma:SolidPeso molecular:1002.05Relamorelin TFA
CAS:<p>Relamorelin (RM-131) TFA: ghrelin analog, GHSR agonist, 0.42 nM affinity, boosts growth hormone, enhances gastric emptying, potential in motility disorders.</p>Fórmula:C45H51F3N8O7SCor e Forma:SolidPeso molecular:905Prepro-ANF (56-92), human
CAS:<p>Human prepro-ANF (56-92) activates renal guanylate cyclase and boosts its activity.</p>Fórmula:C173H270N44O57Cor e Forma:SolidPeso molecular:3878.26Protease-Activated Receptor-1, PAR-1 Agonist TFA
<p>PAR-1 Agonist TFA: Selective peptide, mimics thrombin, activates PAR-1 receptor.</p>Cor e Forma:Liquid(Trp7,β-Ala8)-Neurokinin A (4-10)
CAS:<p>(Trp7,β-Ala8)-Neurokinin A (4-10) is a potent neurokinin-3 (NK3) antagonist [1] .</p>Fórmula:C41H57N9O10SCor e Forma:SolidPeso molecular:868.01Cyclosomatostatin TFA
<p>Cyclosomatostatin TFA blocks SST receptor, reduces CRC cell growth, ALDH+ size, and sphere-formation.</p>Fórmula:C46H58F3N7O8Cor e Forma:SolidPeso molecular:893.99Sauvagine TFA
<p>Sauvagine TFA: frog-derived, 40-amino-acid CRF agonist; stimulates ACTH release, affects diuresis, cardiovascular system, endocrine glands.</p>Fórmula:C204H347F3N56O65S1Cor e Forma:SolidPeso molecular:4713.33Oxmetidine FA
<p>Oxmetidine FA is an orally available specific histamine H2 receptor antagonist with antiulcerogenic properties.</p>Fórmula:C20H23N5O5SPureza:97.34%Cor e Forma:SoildPeso molecular:445.49MLS1082
CAS:<p>MLS1082 is a D1-like dopamine receptor (D1R) orthosteric modulatothat stimulates G-protein signaling upon dopamine activation for neurodegenerative disorders.</p>Fórmula:C24H23N3O2Pureza:99.53%Cor e Forma:SolidPeso molecular:385.46(D-Phe6,Leu-NHEt13,des-Met14)-Bombesin (6-14)
CAS:<p>(D-Phe6,Leu-NHEt13,des-Met14)-Bombesin (6-14), a bombesin (BBN) antagonist, holds potential for cancer research applications [1].</p>Fórmula:C49H69N13O9Cor e Forma:SolidPeso molecular:984.15Peptide YY (pig)
CAS:<p>Peptide YY (pig), a 36 amino acid gut peptide from porcine duodenum, reduces appetite via Y2 receptor, affecting digestion and the heart.</p>Fórmula:C190H288N54O57Cor e Forma:SolidPeso molecular:4240.72Prostaglandin K1
CAS:<p>Prostaglandin K1 (compound 46) is a structurally modified prostanoid analog with an EC50 and Ki of 2800 nM for the EP1 receptor.</p>Fórmula:C20H32O5Cor e Forma:SolidPeso molecular:352.475-HT2A receptor agonist-6
CAS:<p>5-HT2A receptor agonist-6 (compound 47) is a selective agonist of the 5-HT2A receptor with a pEC50 value of 6.58.</p>Fórmula:C18H19N3O3Cor e Forma:SolidPeso molecular:325.36a-Helical Corticotropin Releasing Factor (9-41)
CAS:<p>α-Helical CRF (9-41) is a CRF antagonist that lowers in vivo plasma GH levels.</p>Fórmula:C166H273N45O54S2Cor e Forma:SolidPeso molecular:3827.34Relaxin H3 (human)
CAS:<p>Relaxin H3 (human) is a relaxin peptide that exhibits antifibrotic effects through activation of RXFP1 [1].</p>Cor e Forma:SolidGLP-1R agonist 19
CAS:<p>GLP-1R agonist 19 (M3190) is a potent, selective GLP-1 receptor agonist that demonstrates excellent plasma and liver microsomal stability, along with low hERG toxicity [1].</p>Fórmula:C94H136FN21O25Cor e Forma:SolidPeso molecular:1979.21[Nle13]-Motilin
CAS:<p>[Nle13]-Motilin, a motilin analogue, is a motilin receptor agonist [1] [2] .</p>Fórmula:C121H190N34O35Cor e Forma:SolidPeso molecular:2681.01ACTH (3-24) (human, bovine, mouse, ovine, porcine, rabbit, rat)
CAS:<p>ACTH (3-24) is the fragment 3-24 of ACTH, used in disease research including cancer and immune disorders.</p>Fórmula:C124H196N38O27SCor e Forma:SolidPeso molecular:2683.19Bz-Dab(nbd)-awfpp-nle-NH2
CAS:<p>Bz-Dab(nbd)-ala-trp-phe-pro-pro-nle-NH2 is a fluorescent NK2 antagonist.</p>Fórmula:C56H65N13O11Cor e Forma:SolidPeso molecular:1096.2Ceruletide Ammonium Salt
<p>Ceruletide Ammonium Salt is a decapeptide, originating from the skin of tropical frogs, which is a potent cholecystokinin receptor agonist and a safe and</p>Fórmula:C58H77N14O21S2Pureza:98.47% - 98.54%Cor e Forma:SoildPeso molecular:1370.444-Hydroxy MPT
CAS:<p>4-Hydroxy MPT (4-OH-MPT) is a serotonin-active compound that acts as an agonist for 5-HT2A and 5-HT2B receptors, with EC50 values of 3.82 nM and 3.4 nM, respectively.</p>Fórmula:C14H20N2OCor e Forma:SolidPeso molecular:232.32exo-Tetrahydrocannabivarin
CAS:<p>exo-Tetrahydrocannabivarin (Compound 12) is an analog of Δ9,11-THC. It weakly binds to cannabinoid receptors (CB) with an IC50 of 1.4 μM. In mice, exo-Tetrahydrocannabivarin exhibits activity related to both motor function and analgesia.</p>Fórmula:C19H26O2Cor e Forma:SolidPeso molecular:286.41CCR8 agonist 1
<p>CCR8 agonist1 (Compound 2) is an activator of CCR8 and is applicable in studies related to autoimmune diseases.</p>Fórmula:C22H29NO3Cor e Forma:SolidPeso molecular:355.475-HT1AR agonist 2
<p>5-HT1AR Agonist 2 (Compound 4f) is a potent agonist of the 5-HT1A receptor with a Ki value of 10.0 nM. It also binds to SERT, D2, and 5-HT6 receptors with Ki values of 2.8 nM, 23 nM, and 192 nM, respectively. Furthermore, this compound demonstrates stability in microsomes and induces hypothermia in mice.</p>Fórmula:C31H31N5O3Cor e Forma:SolidPeso molecular:521.61Afubiata
CAS:<p>ADB-FUBIATA is a synthetic cannabinoid studied for its metabolic profile, along with AFUBIATA, CH-FUBIATA, and CH-PIATA. This in vitro analysis by Watanabe S, et al., examines these compounds, as published in "Arch Toxicol," 2023 Dec;97(12):3085-3094.</p>Fórmula:C27H29FN2OCor e Forma:SolidPeso molecular:416.53S1R agonist 2
CAS:<p>S1R agonist 2 is a selective S1R agonist with a Ki of 88 nM for S2R and 1.1 nM for S1R and is protective against ROS and NMDA-induced neurotoxicity.</p>Fórmula:C21H27NOPureza:98.85%Cor e Forma:SolidPeso molecular:309.45Kisspeptin 13
CAS:<p>Kisspeptin 13 activates GPR54 & GnRH receptors, boosts memory, and aids in Alzheimer's research.</p>Fórmula:C78H107N21O18Cor e Forma:SolidPeso molecular:1626.81Methionyl-Lysyl-Bradykinin
CAS:Methionyl-Lysyl-Bradykinin (Met-Lys-Bradykinin), a Bradykinin analogue, is a kinin [1] [2] .Fórmula:C61H94N18O13SCor e Forma:SolidPeso molecular:1319.58YFLLRNP
CAS:<p>YFLLRNP is a biologically active peptide functioning as a partial agonist of PAR-1, selectively activating the G12/13 signaling pathway.</p>Fórmula:C45H67N11O10Cor e Forma:SolidPeso molecular:922.08[8-L-arginine] deaminovasopressin
CAS:<p>[8-L-arginine] deaminovasopressin (dAVP) is a vasopressin analog [1] .</p>Fórmula:C46H64N14O13S2Cor e Forma:SolidPeso molecular:1085.22YM 16638
CAS:YM 16638 is an LT antagonist that can be used to study antigen-induced early and late airway responses in allergic sheep.Fórmula:C18H22N2O5S3Pureza:99.18%Cor e Forma:SolidPeso molecular:442.57Lys-[Des-Arg9]Bradykinin TFA
CAS:<p>Lys-[Des-Arg9]Bradykinin TFA: natural kinin, selective B1 agonist; Ki: 0.12 nM (human), 1.7 nM (mouse), 0.23 nM (rabbit); weak on B2 receptors.</p>Fórmula:C54H75F6N13O15Cor e Forma:SolidPeso molecular:1260.24P4pal10 TFA
<p>P4pal10 TFA, the TFA salt form of P4pal10, serves as an antagonist of the protease-activated receptor 4 (PAR4). This compound inhibits platelet aggregation and thrombin generation induced by tissue factor (TF), exhibiting anticoagulant and antithrombotic activities. Additionally, P4pal10 TFA alleviates carrageenan-induced edema and neutrophil infiltration, and ameliorates damage in rat myocardial ischemia/reperfusion (I/R) models.</p>Cor e Forma:Odour SolidNα-Methylhistamine FA
<p>Nα-Methylhistamine FA is a histamine H3 receptor agonist</p>Fórmula:C7H13N3O2Pureza:>99.99%Cor e Forma:SolidPeso molecular:171.2α-Bulnesene
CAS:α-Bulnesene, a novel PAF (platelet-activating factor) receptor antagonist, exhibits an IC50 of 17.62 μM. It can be isolated from patchouli. α-Bulnesene inhibits both PAF and arachidonic acid-induced aggregation of rabbit platelets.Fórmula:C15H24Cor e Forma:SolidPeso molecular:204.35Cyclosomatostatin Acetate
<p>Cyclosomatostatin Acetate is an effective antagonist of the somatostatin receptor.Cyclosomatostatin Acetate inhibits SSTR1 signaling and decreases cell</p>Fórmula:C46H61N7O8Pureza:98.83%Cor e Forma:SolidPeso molecular:840.02PSB-SB-1203
CAS:<p>PSB-SB-1203 (Compound 25b) is a dual CB1/CB2 ligand that blocks the CB1 receptor and activates the CB2 receptor with a CB1 Ki of 0.244 μM, a CB2 Ki of 0.210 μM, and an EC50 of 0.054 μM. It shows potential for research in obesity and cancer.</p>Fórmula:C25H30O4Cor e Forma:SolidPeso molecular:394.5Somatostatin 1-28 acetate
<p>Somatostatin 1-28 acetate circulates in human plasma.</p>Pureza:99.22%Cor e Forma:SoildBoc-Phe-Leu-Phe-Leu-Phe
CAS:<p>Boc-Phe-Leu-Phe-Leu-Phe is a chemotactic peptide antagonist that inhibits the release of peptide leukotrienes induced by FMLP.</p>Fórmula:C44H59N5O8Cor e Forma:SolidPeso molecular:785.97Tetrapeptide-1
CAS:<p>Tetrapeptide-1 is a bioactive peptide renowned for its antioxidant properties and has been cited as an ingredient in cosmetics [1].</p>Fórmula:C20H36N4O6Pureza:98%Cor e Forma:SolidPeso molecular:428.52Sulfatroxazole
CAS:<p>Sulfatroxazole (Isosulfafurazole) (compound 12) is a selective antagonist of the ETA receptor with an IC50 of 0.26 μM.</p>Fórmula:C11H13N3O3SCor e Forma:SolidPeso molecular:267.3CACPD2011a-0001278239
CAS:<p>CACPD2011a-0001278239 is a β2AR hybrid agonist with high affinity binding to both the wild-type and T164I β2AR variants. It exhibits neither cytotoxicity nor mutagenicity, making it suitable for asthma research.</p>Fórmula:C21H22N4O4Cor e Forma:SolidPeso molecular:394.4220-SOLA
<p>20-SOLA is the first water-soluble 20-HETE antagonist with oral bioavailability. It significantly improves blood pressure changes and kidney damage associated with the streptozotocin (STZ) diabetic mouse model. Additionally, 20-SOLA acts as a GPR75 receptor blocker. This compound is useful in research related to cardiovascular pathology.</p>Fórmula:C33H62O9Peso molecular:602.43938[D-Pro2] Spantide I TFA
<p>[D-Pro2] Spantide I TFA is an analog of Spantide I, a selective antagonist of the NK1 receptor [1].</p>Fórmula:C75H108N20O13·xC2HF3O2Pureza:98%Cor e Forma:Solid
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