GPCR/Proteína-G
Os inibidores de GPCR/proteínas G são compostos que têm como alvo os receptores acoplados a proteínas G (GPCRs) e as proteínas G associadas, que desempenham papéis críticos na transmissão de sinais do exterior para o interior das células. Esses inibidores são essenciais para estudar as vias de sinalização mediadas por GPCRs, que estão envolvidas em numerosos processos fisiológicos, incluindo percepção sensorial, resposta imunológica e neurotransmissão. Os inibidores de GPCR também são importantes no desenvolvimento de medicamentos, pois muitos agentes terapêuticos têm como alvo esses receptores. Na CymitQuimica, oferecemos uma ampla gama de inibidores de GPCR/proteínas G de alta qualidade para apoiar sua pesquisa em farmacologia, biologia celular e áreas afins.
Subcategorias de "GPCR/Proteína-G"
- Receptor 5-HT(942 produtos)
- Receptor de adenosina(242 produtos)
- Receptor adrenérgico(2.949 produtos)
- Receptor de Bombesina(30 produtos)
- Receptor de Bradicinina(59 produtos)
- CXCR(149 produtos)
- CaSR(32 produtos)
- Receptor de Canabinóides(195 produtos)
- Receptor de Dopamina(410 produtos)
- Receptor Endotelina(75 produtos)
- Receptor GNRH(73 produtos)
- GPCR19(31 produtos)
- GRK(32 produtos)
- GTPase(21 produtos)
- Receptor Glucagon(166 produtos)
- Hedgehog/Smoothened(45 produtos)
- Receptor de Histamina(359 produtos)
- Receptor LPA(21 produtos)
- Receptor de Melatonina(24 produtos)
- Receptor OX(40 produtos)
- Receptor opioide(298 produtos)
- PAFR(11 produtos)
- PKA(49 produtos)
- Receptor S1P(17 produtos)
- SGLT(30 produtos)
- Receptor Sigma(46 produtos)
Exibir 18 mais subcategorias
Foram encontrados 5378 produtos de "GPCR/Proteína-G"
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NBI-34041
CAS:<p>NBI-34041: High-affinity CRF1 antagonist; reduces endocrine responses to CRF challenges.</p>Fórmula:C22H26Cl2N4Cor e Forma:SolidPeso molecular:417.37Prostaglandin D2-1-glyceryl ester
CAS:<p>Prostaglandin D2-1-glyceryl ester (PGD2-G; PGD2 2-glyceryl ester) is a chemical compound known for its significance in various biological processes. This compound, commonly referred to by its abbreviations PGD2-G or PGD2 2-glyceryl ester, plays a crucial role in the mediation of physiological functions.</p>Fórmula:C23H38O7Cor e Forma:SolidPeso molecular:426.55OMDM-5
CAS:<p>OMDM-5 is a potent vanilloid receptor type 1 (TRPV1, EC50 = 75 nM) agonist, showing weak ligand activity at cannabinoid type 1 receptor (CB1, Ki=4.9 μM).</p>Fórmula:C26H44N2O3Pureza:99.73%Cor e Forma:SolidPeso molecular:432.64SB-649701
CAS:<p>SB-649701 is a potent antagonist of the human CCR8 receptor, exhibiting a pIC50 value of 7.7, and is utilized in asthma research [1].</p>Fórmula:C27H28N4O3Pureza:98%Cor e Forma:SolidPeso molecular:456.54IPG7236
CAS:<p>IPG7236, a selective CCR8 antagonist, demonstrates notable tumor suppression in a mouse xenograft model of human breast cancer and is applicable in cancer</p>Fórmula:C23H31N3O3SPureza:98%Cor e Forma:SolidPeso molecular:429.58Prostaglandin E1 ethanolamide
CAS:<p>Prostaglandin E1 ethanolamide, an analog of Prostaglandin E1 (PGE1), can potentially inhibit the GLI2-induced expression of target genes such as Gli1 and Ptch1, thereby reducing tumor growth [1].</p>Fórmula:C22H39NO5Cor e Forma:SolidPeso molecular:397.55GR 125487 sulfamate
CAS:<p>GR 125487 sulfamate is a 5-HT4 receptor antagonist.</p>Fórmula:C19H29FN4O8S2Pureza:98%Cor e Forma:SolidPeso molecular:524.58Dibenamine hydrochloride
CAS:<p>Dibenamine hydrochloride is a competitive and irreversible blocking agent of the β-adrenergic receptor.</p>Fórmula:C16H19Cl2NPureza:96.43%Cor e Forma:Oily Liquid SolidPeso molecular:296.23CRTH2-IN-1
CAS:CRTH2-IN-1 is a selective prostaglandin D2 receptor DP2 (CRTH2) antagonist, a Ramatroban analog, with an IC50 of 6 nM in the human DP2 binding assay.Fórmula:C21H21FN2O4SPureza:98%Cor e Forma:SolidPeso molecular:416.47UCB-35440
CAS:<p>UCB-35440, a 5-lipoxygenase inhibitor and a histamine H1 receptor antagonist, is used potentially for the treatment of dermatitis.</p>Fórmula:C31H34ClN5O4Cor e Forma:SolidPeso molecular:576.09Alclofenac
CAS:<p>Alclofenac (W-7320) aids chronic rheumatism by affecting acute phase proteins and L-tryptophan binding.</p>Fórmula:C11H11ClO3Pureza:99.89%Cor e Forma:SolidPeso molecular:226.66(±)-Fabesetron hydrochloride
CAS:<p>FK1052 hydrochloride is a potent 5-HT3 and 5-HT4 receptor dual antagonist.</p>Fórmula:C18H20ClN3OPureza:98%Cor e Forma:SolidPeso molecular:329.82L-796568 dihydrochloride
CAS:<p>L-796568: potent β3 agonist (EC50 = 3.6 nM), >600-fold selectivity vs β1/β2, good oral bioavailability, long action.</p>Fórmula:C31H29Cl2F3N4O3S2Cor e Forma:SolidPeso molecular:697.62Hemopressin(rat) TFA
CAS:<p>Hemopressin(rat) TFA, a nonapeptide from hemoglobin α1-chain, selectively inhibits CB1 receptors and reduces inflammatory pain.</p>Fórmula:C55H78F3N13O14Cor e Forma:SolidPeso molecular:1202.285-HT3-In-1
CAS:5-HT3-In-1 (compound example 8) exhabits with 5-HT3 inhibition activity.Fórmula:C16H21ClN4O3Pureza:98%Cor e Forma:SolidPeso molecular:352.822-Chloro-ATP
CAS:2-Chloro-ATP is a soluble inhibitor of guanylate cyclase (guanylate cyclase) that can increase intracellular calcium ion concentrations at low concentrations through a mechanism independent of inositol phosphate production.Fórmula:C10H15ClN5O13P3Cor e Forma:SolidPeso molecular:541.632-Furoyl-LIGRLO-amide TFA
CAS:<p>2-Furoyl-LIGRLO-amide TFA is a potent and selective agonist of the proteinase-activated receptor 2 (PAR2), exhibiting a pD2 value of 7.0 [1] [2].</p>Fórmula:C38H64F3N11O10Cor e Forma:SolidPeso molecular:891.98Bima SA
CAS:<p>Bimatoprost Serinol Amide (Bima SA), a prostaglandin analog, shows research potential for glaucoma [1].</p>Fórmula:C26H39NO6Cor e Forma:SolidPeso molecular:461.59Gentisein
CAS:<p>Gentisein (NSC-329491), a primary metabolite of Mangiferin, exhibits significant inhibition of serotonin uptake, demonstrating potency with an IC50 value of 4.7</p>Fórmula:C13H8O5Pureza:96.89%Cor e Forma:SolidPeso molecular:244.2CY 208-243
CAS:CY 208-243 is a selective dopamine D1 receptor agonist with anti-Parkinson disease activity.Fórmula:C19H18N2Pureza:98%Cor e Forma:SolidPeso molecular:274.36RXFP1 receptor agonist-8
CAS:<p>Example 2 (RXFP1 receptor agonist-8) is a potent RXFP1 receptor agonist that suppresses cAMP production in HEK293 cells expressing human RXFP1, exhibiting an</p>Fórmula:C40H36F5N3O7Cor e Forma:SolidPeso molecular:765.72NK3R-IN-1
CAS:<p>NK3R-IN-1 (compound 16x), an orally active imidazolepiperazine derivative, acts as a Neurokinin Receptor NK3R inhibitor and has been shown to reduce blood</p>Fórmula:C17H16FN5OSPureza:98%Cor e Forma:SolidPeso molecular:357.41LTB4 antagonist 3
CAS:<p>Compound 24e, a leukotriene B4 (LTB4) antagonist, exhibits an inhibitory concentration 50 (IC50) of 477 nM and demonstrates anti-inflammatory activity [1].</p>Fórmula:C29H27NO6Pureza:98%Cor e Forma:SolidPeso molecular:485.53AM841
CAS:<p>AM841, a high-affinity electrophilic ligand, covalently interacts with a cysteine residue in helix six, thus activating the CB1 cannabinoid receptor.</p>Fórmula:C26H39NO3SPureza:98%Cor e Forma:SolidPeso molecular:445.66Bivamelagon hydrochloride
CAS:<p>MC-4R Agonist 2 hydrochloride (Example 1) serves as an MC4R agonist, with applications in researching obesity, diabetes, inflammation, and erectile dysfunction.</p>Fórmula:C35H54Cl2N4O4Pureza:100%Cor e Forma:SolidPeso molecular:665.73Ro-24-0238
CAS:<p>Ro-24-0238 blocks PAF, curbing thromboxane creation and inflammation caused by PAF release.</p>Fórmula:C27H36N2O2Pureza:98%Cor e Forma:SolidPeso molecular:420.59(Rac)-PF-4136309(1341224-83-6 Free base)
CAS:<p>PF-4136309 (INCB8761, PF-04136309) is a highly effective and selective oral CCR2 antagonist with good bioavailability, with an IC50 value of 5.2 nM for human</p>Fórmula:C29H31F3N6O3Cor e Forma:SolidPeso molecular:568.59NAS181
CAS:<p>rat 5-HT1B receptor antagonist</p>Fórmula:C21H34N2O10S2Pureza:98%Cor e Forma:SolidPeso molecular:538.63BLT2 antagonist-1
CAS:<p>BLT2 antagonist-1 (compound 15b) is a selective inhibitor of the BLT2 receptor, impeding the chemotaxis of CHO-BLT2 cells at an IC50 of 224 nM, while not</p>Fórmula:C26H26FNO4Pureza:98%Cor e Forma:SolidPeso molecular:435.49RXFP1 receptor agonist-1
CAS:<p>RXFP1 receptor agonist-1 (Example 2), an agonist of the RXFP1 receptor, suppresses cAMP production in HEK293 cells that constitutively express the human RXFP1,</p>Fórmula:C31H29F7N2O4Cor e Forma:SolidPeso molecular:626.56A1/A3 AR antagonist 3
CAS:<p>A1/A3 AR Antagonist 3 is a dual A1R/A3R antagonist that demonstrates high affinity within the low-micromolar to nanomolar range, and is potentially useful in</p>Fórmula:C22H19N5O3Pureza:98%Cor e Forma:SolidPeso molecular:401.422-Linoleoyl Glycerol
CAS:<p>2-Arachidonoyl glycerol (2-AG), a natural endocannabinoid ligand for the CB1 receptor, was isolated from porcine brain and characterized. Its congener, 2-linoleoyl glycerol (2-LG), which has a linoleoyl group instead of an arachidonoyl group, also exists alongside 2-AG in vivo. While 2-LG exhibits low intrinsic activity, it enhances the activity of 2-AG and other endocannabinoids through an "entourage" effect, attributed to the inhibition of breakdown and reuptake pathways that typically decrease endocannabinoid levels post-release.</p>Fórmula:C21H38O4Cor e Forma:SolidPeso molecular:354.531ATP-γ-S tetrasodium
CAS:<p>Collagen, Type I, from bovine achilles tendon is a type I collagen extracted from bovine achilles tendon.</p>Fórmula:C10H12N5Na4O12P3SCor e Forma:SolidPeso molecular:611.17CB1 inverse agonist 1
CAS:<p>MRL-650 is an oral, selective CB1 agonist; IC50: CB1=7.5 nM, CB2=4100 nM; anorexigenic effects noted.</p>Fórmula:C25H18Cl3N3O3Pureza:99.92%Cor e Forma:SolidPeso molecular:514.79TG6-129
CAS:<p>TG6-129 is an EP2 receptor antagonist, blocking PGE2 effects, reducing inflammatory markers with 1.6 µM IC50.</p>Fórmula:C20H18FN5O3S3Pureza:99.55%Cor e Forma:SolidPeso molecular:491.58PNU109291
CAS:<p>PNU109291, a potent and selective agonist of the 5-HT1D receptor, effectively mitigates dural plasma extravasation induced by trigeminal ganglion stimulation.</p>Fórmula:C24H31N3O3Pureza:98%Cor e Forma:SolidPeso molecular:409.52Fazamorexant
CAS:<p>Fazamorexant (YZJ-1139) is a powerful orexin receptor antagonist effective for insomnia research.</p>Fórmula:C25H25FN4O2Cor e Forma:SolidPeso molecular:432.49Kisspeptin 234 TFA
CAS:<p>Kisspeptin 234 TFA is a 10-amino acid peptide analog of Kisspeptin 10 [1] that functions as an antagonist to the kisspeptin receptor (KISS1, GPR54).</p>Fórmula:C63H78N18O13·xC2HF3O2Cor e Forma:SolidPeso molecular:1409.43MK-0493
CAS:<p>MK-0493 is an effective and selective agonist of the melanocortin receptor 4 (MC4R). It also demonstrated significant reductions in energy intake.</p>Fórmula:C30H38ClF2N3O2Pureza:98%Cor e Forma:SolidPeso molecular:546.09L 163255
CAS:<p>L 163255 is a type of growth hormone secretagogue (GHS).</p>Fórmula:C28H38N4O4SCor e Forma:SolidPeso molecular:526.69GR 127935 hydrochloride
CAS:5-HT1B/1D receptor antagonistFórmula:C29H32ClN5O3Pureza:98%Cor e Forma:SolidPeso molecular:534.05CCG-63808
CAS:CCG-63808 is a reversible inhibitor of regulator of G-protein signaling (RGS) proteins.Fórmula:C25H15FN4O2SPureza:90%Cor e Forma:SolidPeso molecular:454.48GW405833 hydrochloride
CAS:<p>GW405833 hydrochloride, a potent and selective agonist of the cannabinoid-2 (CB2) receptor (EC 50 = 0.65 nM; maximum inhibition = 44.6%), exhibits significant antihyperalgesic effects in various rodent pain models [1] [2] [3].</p>Fórmula:C23H25Cl3N2O3Cor e Forma:SolidPeso molecular:483.82GS-6201
CAS:<p>GS-6201 (CVT-6883) is a selective antagonist of adenosine A2B receptor.</p>Fórmula:C21H21F3N6O2Pureza:99.74% - 99.78%Cor e Forma:SolidPeso molecular:446.43BAY 73-1449
CAS:<p>BAY 73-1449 is a selective and potent antagonist of the prostacyclin receptor(IC50<0.1 nM).</p>Fórmula:C26H23N3O3Pureza:99.77%Cor e Forma:SolidPeso molecular:425.48MSX-2
CAS:<p>MSX-2 is an A2A adenosine receptor antagonist.</p>Fórmula:C21H22N4O4Pureza:98%Cor e Forma:SolidPeso molecular:394.42RS100329 hydrochloride
CAS:RS 100329 hydrochloride is an antagonist of α1A-adrenergic receptor.Fórmula:C20H26ClF3N4O3Pureza:99.95%Cor e Forma:SolidPeso molecular:462.89β3-AR agonist 1
CAS:β3-AR agonist 1 is a highly selective, and orally available agonist of β3-adrenergic receptor (EC50: 18 nM), being inactive to β1-, β2-, and α1A-AR (β1/β3, β2/Fórmula:C22H28N4O4SPureza:98%Cor e Forma:SolidPeso molecular:444.55Befiradol
CAS:Befiradol (NLX-112) is an agonist of 5-HT1A receptor.Fórmula:C20H22ClF2N3OCor e Forma:SolidPeso molecular:393.86AGN 210676
CAS:AGN 210676 is a selective agonist of prostaglandin EP2(EC50 : 5 nM).Fórmula:C23H29NO5SPureza:98%Cor e Forma:SolidPeso molecular:431.55PF-04634817 succinate
CAS:<p>PF-0463481 succinate is a potent and orally active dual antagonist of CCR2/CCR5 with comparable human and rodent CCR2 potency with IC50 of 20.8 nM.</p>Fórmula:C29H42F3N5O7Pureza:98%Cor e Forma:SolidPeso molecular:629.67DU-125530
CAS:<p>DU-125530 is a 5-HT1A receptor antagonist.</p>Fórmula:C23H26ClN3O5SCor e Forma:SolidPeso molecular:491.99S1PL-IN-31
CAS:<p>S1PL-IN-31 is a dual-function chemical compound acting as an inhibitor of sphingosine-1-phosphate (S1P) lyase with an IC50 value of 210 nM and as an antagonist</p>Fórmula:C26H23ClN6Cor e Forma:SolidPeso molecular:454.95PD-140548
CAS:<p>PD-140548 is a potent, CCKA receptor-selective antagonist.</p>Fórmula:C33H39N3O5Pureza:98%Cor e Forma:SolidPeso molecular:557.68Macimorelin acetate
CAS:<p>Macimorelin acetate (EP-1572) is an oral GHSR agonist for AGHD and CACS research.</p>Fórmula:C28H34N6O5Cor e Forma:SolidPeso molecular:534.61Pronetalol
CAS:<p>Pronethalol ((±)-Pronethalol), a non-selective β-adrenergic antagonist, effectively inhibits Sox2 expression and offers protection against Digitalis-induced ventricular arrhythmias. Additionally, it can reverse such arrhythmias and limit the development of cerebral arteriovenous malformations (AVMs) [1] [2].</p>Fórmula:C15H19NOCor e Forma:SolidPeso molecular:229.32S1P5 receptor agonist-1
CAS:<p>S1P5 Receptor Agonist-1 (example 6) is a highly potent and selective agonist for the S1P5 receptor, exhibiting an EC50 value of 20 nM.</p>Fórmula:C20H24F3NO3Cor e Forma:SolidPeso molecular:383.4RXFP1 receptor agonist-4
CAS:<p>RXFP1 receptor agonist-4 (Example 268) is an agonist for the RXFP1 receptor, demonstrated to suppress cAMP production in HEK293 cells that stably express the</p>Fórmula:C32H24F7N3O5SCor e Forma:SolidPeso molecular:695.6Dihydrexidine
CAS:<p>Dihydrexidine is a full efficacy D1-like dopamine receptor (D1/D5) agonist (IC50: 10 nM for D1 receptor). It also shows potent antiparkinsonian activity.</p>Fórmula:C17H17NO2Pureza:98%Cor e Forma:SolidPeso molecular:267.32Sigma-1 receptor antagonist 3
CAS:<p>Sigma-1 receptor antagonist 3 is a more potent and selective antagonist of Sigma-1 (σ1) receptor (Ki = 1.14 nM) than σ2 receptor(Ki = 1239 nM).</p>Fórmula:C19H23ClFN3OPureza:99.95%Cor e Forma:SolidPeso molecular:363.86JNJ-37822681 dihydrochloride
CAS:<p>JNJ-37822681 dihydrochloride 是特异性的、有中枢活性的，可快速解离的多巴胺 D2受体拮抗剂，与多巴胺 D2L 受体结合的亲和力适中 (Ki=158 nM)。JNJ-37822681 dihydrochloride 在精神分裂症和躁郁症领域有研究价值。</p>Fórmula:C17H19Cl2F5N4Pureza:99.78%Cor e Forma:SolidPeso molecular:445.26LY108742
CAS:<p>LY108742 is an antagonist of 5-HT2.</p>Fórmula:C21H28N2O3Pureza:98%Cor e Forma:SolidPeso molecular:356.46Ginkgolic acid 2-phosphate
CAS:<p>Ginkgolic acid 2-phosphate, a potent sphingosine 1-phosphate (S1P) agonist, induces ERK phosphorylation and interacts with S1P1 [1].</p>Fórmula:C22H37O6PCor e Forma:SolidPeso molecular:428.5RXFP1 receptor agonist-3
CAS:<p>RXFP1 receptor agonist-3 (Example 223) is an agonist of the RXFP1 receptor that inhibits cyclic AMP (cAMP) production in HEK293 cells stably expressing human</p>Fórmula:C42H34F9N3O5Cor e Forma:SolidPeso molecular:831.72CGS 21680
CAS:<p>CGS 21680 is a chemical compound that acts as a selective agonist for both adenosine and its A2A receptor, demonstrating a binding affinity (K i) of 27 nM.</p>Fórmula:C23H29N7O6Cor e Forma:SolidPeso molecular:499.52Veldoreotide TFA
CAS:<p>Veldoreotide (DG3173) TFA, a somatostatin analogue, effectively binds to and activates somatostatin receptors (SSTR) 2, 4, and 5. This compound demonstrates a higher efficacy in inhibiting growth hormone (GH) secretion in adenomas than Octreotide, showcasing its potential as a pain modulating agent [1].</p>Fórmula:C62H75F3N12O12Cor e Forma:SolidPeso molecular:1237.33(Rac)-Modipafant
CAS:<p>(Rac)-Modipafantis a PAFR antagonist that inhibits PAF-induced aggregation of washed platelets in rabbits.</p>Fórmula:C34H29ClN6O3Pureza:97.96% - 98.09%Cor e Forma:SolidPeso molecular:605.09Velagliflozin
CAS:Velagliflozin is an orally available inhibitor of sodium-glucose cotransporter 2.Fórmula:C23H25NO5Pureza:98%Cor e Forma:SolidPeso molecular:395.45(+)-Dihydrexidine hydrochloride
CAS:<p>(+)-Dihydrexidine hydrochloride is an agonist of dopamine D1 receptor(EC50 of 72± 21 nM).</p>Fórmula:C17H18ClNO2Pureza:98%Cor e Forma:SolidPeso molecular:303.78Velagliflozin proline hydrate
CAS:<p>Velagliflozin proline hydrate, an oral SGLT2 inhibitor, reduces blood sugar by inhibiting renal glucose reabsorption.</p>Fórmula:C28H36N2O8Cor e Forma:SolidPeso molecular:528.59PSB-1115 potassium salt
CAS:<p>PSB-1115 potassium salt, a selective A2B Adenosine Receptor antagonist, inhibits the 2,4,6-trinitrobenzenesulfonic acid (TNBS)-induced contraction inhibition of acetylcholine (ACh) [1].</p>Fórmula:C14H13KN4O5SCor e Forma:SolidPeso molecular:388.44Carmoxirole hydrochloride
CAS:<p>Carmoxirole hydrochloride (EMD 45609 hydrochloride) is a selective dopamine D2 receptor agonist with antihypertensive activity in vivo.</p>Fórmula:C24H27ClN2O2Pureza:99.37% - 99.62%Cor e Forma:SolidPeso molecular:410.94AL 8810 methyl ester
CAS:<p>AL 8810 methyl ester, a prostaglandin F(2α) analog and receptor agonist, competitively antagonizes FP receptor agonist Fluprostenol effects. It lacks significant potency against TP, DP, EP(2), EP(4) receptor subtypes in cell lines [1].</p>Fórmula:C25H33FO4Cor e Forma:SolidPeso molecular:416.53Y1R probe-1
CAS:<p>Compound 39, or Y1R probe-1, is a fluorescent probe for Neuropeptide Y Y1 Receptor used in cancer research.</p>Fórmula:C64H71F3N10O12Cor e Forma:SolidPeso molecular:1229.3Tarazepide
CAS:Tarazepide is a potent and specific antagonist of CCK-A receptor.Fórmula:C28H24N4O2Pureza:98%Cor e Forma:SolidPeso molecular:448.52RXFP1 receptor agonist-7
CAS:<p>RXFP1 receptor agonist-7 (Example 2) serves as an RXFP1 receptor agonist, effectively inhibiting cAMP production in HEK293 cells that stably express the human</p>Fórmula:C40H32F5N3O7Cor e Forma:SolidPeso molecular:761.69EP4 receptor agonist 2
CAS:<p>EP4 receptor agonist 2 (compound 31) is a potent EP4 receptor agonist, demonstrating an EC50 value of 0.8 nM and K_i values of >100,000, 38,000, and 3.1 nM for the EP2, EP3, and EP4 receptors, respectively [1].</p>Fórmula:C27H32ClNO4Cor e Forma:SolidPeso molecular:470.01(-)-Isoproterenol hydrochloride
CAS:<p>(-)-Isoproterenol hydrochloride is used as a β-adrenergic receptor agonist in the treatment of bradycardia and as a bronchodilator.</p>Fórmula:C11H17NO3·CIHCor e Forma:SolidPeso molecular:247.72MK-1421
CAS:<p>MK-1421 is a potent and selective sstr3 antagonist.</p>Fórmula:C27H24FN9O2Cor e Forma:SolidPeso molecular:525.54O-Arachidonoyl glycidol
CAS:<p>O-Arachidonoyl glycidol (compound 1), a 2-arachidonoylglycerol (2-AG) analog, effectively inhibits the hydrolysis of cytosolic 2-oleoylglycerol (2-OG) with an IC50 value of 4.5 µM, and also blocks 2-OG and anandamide hydrolysis in membrane fractions with IC50 values of 19 µM and 12 µM, respectively [1].</p>Fórmula:C23H36O3Cor e Forma:SolidPeso molecular:360.53Heptadecanoyl ethanolamide
CAS:<p>Heptadecanoyl ethanolamide, an endogenous cannabinoid, serves as a synthetic analog of PEA, featuring an odd-numbered (17-carbon) fatty acid chain [1].</p>Fórmula:C19H39NO2Cor e Forma:SolidPeso molecular:313.52TGR5 agonist 3
CAS:<p>Compound 8, a cholic acid derivative, functions as a selective TGR5 agonist and exhibits an EC50 value of 5 μM [1].</p>Fórmula:C28H48O5Cor e Forma:SolidPeso molecular:464.68Orexin receptor antagonist 4
CAS:<p>Orexin antagonist 4: potent, selective for OX2R (IC50=4.27 nM); less for OX1R (IC50=295 nM).</p>Fórmula:C22H24FN5O2Cor e Forma:SolidPeso molecular:409.46MIN-117
CAS:MIN-117, a SSRI/5-HT receptor antagonist, is potentially used for the treatment of depression.Fórmula:C25H26Cl3N3O4Pureza:98%Cor e Forma:SolidPeso molecular:538.85MNI-444
CAS:<p>MNI-444 is a PET radiotracer for adenosine 2A receptors.</p>Fórmula:C24H26FN9O2Cor e Forma:SolidPeso molecular:491.52MB-28767
CAS:<p>MB-28767 is an agonist of prostaglandin E2 (PGE2) receptor.</p>Fórmula:C22H30O5Cor e Forma:SolidPeso molecular:374.47MRS 1754
CAS:<p>MRS 1754 is a selective antagonist radioligand for the A2B adenosine receptor. It has a very low affinity for A1 and A3 receptors of both humans and rats.</p>Fórmula:C26H26N6O4Pureza:97.57% - 99.3%Cor e Forma:SolidPeso molecular:486.52SUCNR1-IN-1
CAS:<p>SUCNR1-IN-1 (Compound 20) serves as a potent SUCNR1 inhibitor, exhibiting an IC50 of 88 nM against hSUCNR1.</p>Fórmula:C26H22ClF3N2O4Cor e Forma:SolidPeso molecular:518.91Glucagon receptor antagonists-3
CAS:<p>Glucagon receptor antagonist -3 is a highly effective glucagon receptor antagonist.</p>Fórmula:C22H30FNO2Pureza:98%Cor e Forma:SolidPeso molecular:359.48SRX246
CAS:<p>SRX246: potent CNS-penetrant V1a antagonist (Ki=0.3 nM), inactive at V1b/V2, negligible binding at 64 other receptor classes.</p>Fórmula:C42H49N5O5Pureza:98%Cor e Forma:SolidPeso molecular:703.87KP496
CAS:<p>KP496 is a selective, dual antagonist for Thromboxane A2 receptor and Leukotriene D4 receptor.</p>Fórmula:C31H34ClN3O7S3Pureza:98%Cor e Forma:SolidPeso molecular:692.27Prostaglandin E2 serinol amide
CAS:<p>Prostaglandin E2 Serinol Amide acts as a weak inhibitor against the hydrolysis of [3H]2-oleoylglycerol, but it is non-hydrolyzable and cannot produce PGE2. Consequently, it is unable to inhibit leukotriene B4 biosynthesis, superoxide production, migration, and the release of antimicrobial peptides [1].</p>Fórmula:C23H39NO6Cor e Forma:SolidPeso molecular:425.566FPPQ
CAS:<p>FPPQ blocks 5-HT3 and 5-HT6 receptors (Ki: 0.9 & 3 nM) and may improve psychosis and cognition.</p>Fórmula:C21H19FN4O2SCor e Forma:SolidPeso molecular:410.46Amtolmetin guacil
CAS:Amtolmetin guacil (ST-679) 抑制前列腺素合成和环氧合酶。 Amtolmetin guacil 具有与托美汀类似的 NSAID 特性，具有额外的镇痛、解热和胃保护特性。Fórmula:C24H24N2O5Pureza:99.85%Cor e Forma:White Needle-Shaped CrystalPeso molecular:420.4615(S)-Fluprostenol
CAS:<p>15(S)-Fluprostenol, an isomer of the FP receptor agonist fluprostenol, serves as a potential active metabolite of 15(S)-fluprostenol isopropyl ester. It can function as an agonist at FP receptors, though with lower potency compared to its 15(R) epimer, fluprostenol.</p>Fórmula:C23H29F3O6Cor e Forma:SolidPeso molecular:458.5BI-167107
CAS:<p>BI-167107 is a high affinity, full agonist that binds to the β2 adrenergic receptor (β2AR, Kd of 84 pM).</p>Fórmula:C21H26N2O4Cor e Forma:SolidPeso molecular:370.444-hydroxy Nebivolol hydrochloride
CAS:<p>4-Hydroxy Nebivolol, a primary metabolite of Nebivolol, results from the enzymatic hydroxylation of Nebivolol by the cytochrome P450 (CYP) isoform CYP2D6.</p>Fórmula:C22H25F2NO5HClCor e Forma:SolidPeso molecular:457.9CV1808
CAS:<p>CV-1808 is a coronary vasodilator, antihypertensive, and antipsychotic following systemic administration in vivo. CV-1808 is an adenosine A2 receptor agonist.</p>Fórmula:C16H18N6O4Cor e Forma:Off-White To Pale Yellow SolidPeso molecular:358.35Robalzotan
CAS:<p>Robalzotan is a selective 5-HT1A receptor antagonist.</p>Fórmula:C18H23FN2O2Pureza:98%Cor e Forma:SolidPeso molecular:318.39Amauromine
CAS:<p>Amauromine is a peripherally selective and potent cannabinoid receptor type 1 (CB1) receptor antagonist, a novel alkaloid with vasodilatory activity.</p>Fórmula:C32H36N4O2Cor e Forma:SolidPeso molecular:508.65
