GPCR/Proteína-G
Os inibidores de GPCR/proteínas G são compostos que têm como alvo os receptores acoplados a proteínas G (GPCRs) e as proteínas G associadas, que desempenham papéis críticos na transmissão de sinais do exterior para o interior das células. Esses inibidores são essenciais para estudar as vias de sinalização mediadas por GPCRs, que estão envolvidas em numerosos processos fisiológicos, incluindo percepção sensorial, resposta imunológica e neurotransmissão. Os inibidores de GPCR também são importantes no desenvolvimento de medicamentos, pois muitos agentes terapêuticos têm como alvo esses receptores. Na CymitQuimica, oferecemos uma ampla gama de inibidores de GPCR/proteínas G de alta qualidade para apoiar sua pesquisa em farmacologia, biologia celular e áreas afins.
Subcategorias de "GPCR/Proteína-G"
- Receptor 5-HT(942 produtos)
- Receptor de adenosina(242 produtos)
- Receptor adrenérgico(2.946 produtos)
- Receptor de Bombesina(30 produtos)
- Receptor de Bradicinina(59 produtos)
- CXCR(148 produtos)
- CaSR(32 produtos)
- Receptor de Canabinóides(195 produtos)
- Receptor de Dopamina(408 produtos)
- Receptor Endotelina(76 produtos)
- Receptor GNRH(73 produtos)
- GPCR19(31 produtos)
- GRK(31 produtos)
- GTPase(21 produtos)
- Receptor Glucagon(165 produtos)
- Hedgehog/Smoothened(44 produtos)
- Receptor de Histamina(359 produtos)
- Receptor LPA(21 produtos)
- Receptor de Melatonina(24 produtos)
- Receptor OX(40 produtos)
- Receptor opioide(298 produtos)
- PAFR(11 produtos)
- PKA(48 produtos)
- Receptor S1P(17 produtos)
- SGLT(30 produtos)
- Receptor Sigma(46 produtos)
Exibir 18 mais subcategorias
Foram encontrados 5360 produtos de "GPCR/Proteína-G"
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JNJ-28583867
CAS:<p>JNJ-28583867 is an inhibitor of histamine H(3) receptor antagonist and serotonin reuptake.</p>Fórmula:C24H32N2O2SCor e Forma:SolidPeso molecular:412.59Heptadecanoyl ethanolamide
CAS:<p>Heptadecanoyl ethanolamide, an endogenous cannabinoid, serves as a synthetic analog of PEA, featuring an odd-numbered (17-carbon) fatty acid chain [1].</p>Fórmula:C19H39NO2Cor e Forma:SolidPeso molecular:313.52S1P5 receptor agonist-1
CAS:<p>S1P5 Receptor Agonist-1 (example 6) is a highly potent and selective agonist for the S1P5 receptor, exhibiting an EC50 value of 20 nM.</p>Fórmula:C20H24F3NO3Cor e Forma:SolidPeso molecular:383.4AGN-191129
CAS:<p>AGN-191129 (PGF2α-OMe) is a PGF2α analog with C-1 carboxyl replaced by O-methyl; it lowers eye pressure, but its receptors are unclear.</p>Fórmula:C21H38O4Cor e Forma:SolidPeso molecular:354.52BU-E 75
CAS:<p>BU-E 75 is an agonist of the histamine H2.</p>Fórmula:C21H24F2N6Cor e Forma:SolidPeso molecular:398.452-Thio-UTP tetrasodium
CAS:<p>2-Thio-UTP tetrasodium, a potent agonist for P2Y2, P2Y4, and P2Y6 receptors, serves as a crucial compound in cancer research [1].</p>Fórmula:C9H11N2Na4O14P3SCor e Forma:SolidPeso molecular:588.13(R)-Monlunabant
CAS:<p>(R)-Monlunabant ((R)-MRI-1891) serves as a CB1 receptor antagonist utilized in obesity and metabolic disease research [1].</p>Fórmula:C26H22ClF3N6O3SPureza:98%Cor e Forma:SolidPeso molecular:591Prostaglandin F2α serinol amide
CAS:<p>Prostaglandin F2α serinol amide, a serinolamide G protein-coupled receptor, elevates calcium levels in human non-small cell lung cancer cells. Additionally, Prostaglandin F2α functions as a luteinizing hormone in sheep and potentially serves as a nociceptive mediator in the spinal cord [1] [2] [3].</p>Fórmula:C23H41NO6Cor e Forma:SolidPeso molecular:427.582AC-099 hydrochloride
CAS:<p>AC-099 hydrochloride is a full agonist of neuropeptide FF2 receptor NPFF2R and a partial agonist of neuropeptide FF1 receptor NPFF1R.</p>Fórmula:C9H9Cl2F3N4Pureza:99.86%Cor e Forma:SolidPeso molecular:301.1Quinotolast sodium
CAS:<p>Quinotolast sodium inhibits histamine, LTC4 and PGD2 release in a concentration-dependent manner in the concentration range of 1-100 μg/mL.</p>Fórmula:C17H12N6NaO3Pureza:98%Cor e Forma:SolidPeso molecular:371.312Foropafant
CAS:<p>Foropafant (SR27417) is a highly potent and selective platelet-activating factor (PAF) receptor antagonist (Ki: 57 pM).</p>Fórmula:C28H40N4SPureza:99.67%Cor e Forma:SolidPeso molecular:464.71Nolomirole HCl
CAS:<p>Nolomirole HCl (CHF 1035) is a novel selective dopamine agonist with oral activity and inhibitory effects on norepinephrine release, which can be used to study</p>Fórmula:C19H28ClNO4Pureza:99.03% - >99.99%Cor e Forma:SolidPeso molecular:369.88GSK2263167
CAS:<p>GSK2263167 is an agonist of S1P1 receptor.</p>Fórmula:C25H26N4O4Cor e Forma:SolidPeso molecular:446.5γ-Linolenoyl monoethanolamide
CAS:<p>γ-Linolenoyl monoethanolamide, a fatty N-acyl ethanolamine, acts as an endocannabinoid [1] [2].</p>Fórmula:C20H35NO2Cor e Forma:SolidPeso molecular:321.5052-O-Ethyl PAF C-16
CAS:<p>2-O-Ethyl PAF C-16, a homolog of Platelet-activating Factor (PAF) and competitive ligand for the Platelet-activating Factor Receptor (PAFR), inhibits the binding of PAF antagonist WEB 2086 to PAFR with an IC50 of 21 nM [1].</p>Fórmula:C26H56NO6PCor e Forma:SolidPeso molecular:509.709Lazuvapagon
CAS:<p>Lazuvapagon is a vasopressin V2 receptor agonist that can be used to study enuresis.</p>Fórmula:C27H32N4O3Cor e Forma:SolidPeso molecular:460.572,3-dinor Prostaglandin E1
CAS:<p>Prostaglandin E1 (PGE1), though not predominantly found in nature, plays a significant role in clinical treatments, addressing conditions such as peripheral occlusive vascular disease, erectile dysfunction, and neonatal cardiology issues. The metabolism of PGE1 primarily begins with the oxidation at C-15, producing 13,14-dihydro-15-keto PGE1 as its major metabolite. Alternatively, inhibiting this pathway or overwhelming it with too much PGE1 could potentially enhance the production of 2,3-dinor metabolites, like 2,3-dinor PGE1, though their biological activities remain unreported. Cayman Chemical stands out as a prominent provider of prostaglandins and their metabolites, uniquely manufacturing 2,3-dinor PGE1.</p>Fórmula:C18H30O5Cor e Forma:SolidPeso molecular:326.411(Z),14(Z)-Eicosadienoic acid
CAS:<p>11(Z),14(Z)-Eicosadienoic acid is an unsaturated fatty acid and metabolite that inhibits the binding of [3H]LTB4 to neutrophil modules (Ki=3 μm).</p>Fórmula:C20H36O2Pureza:99.94%Cor e Forma:SolidPeso molecular:308.5Carbidine dihydrochloride
CAS:<p>Carbidine, a gamma-carboline derivative, is an atypical antipsychotic that modulates dopamine release and tyrosine hydroxylase activity.</p>Fórmula:C13H20Cl2N2Pureza:98.59%Cor e Forma:SolidPeso molecular:275.217Robotnikinin
CAS:<p>Robotnikinin is an Shh signaling inhibitor in a concentration-dependent manner. It acts by exhibiting significant repression of Shh-induced Gli1/Gli2.</p>Fórmula:C25H27ClN2O4Pureza:98%Cor e Forma:SolidPeso molecular:454.95PW0464
CAS:<p>PW0464 ((Rac)-Razpipadon) is a non-catechol D1R agonist and potent omplete G protein biased ligand with an EC50 (Gs-cAMP)=5.8 nM for neurological disorders.</p>Fórmula:C19H17F2N3O4Pureza:98.78%Cor e Forma:SolidPeso molecular:389.35N-5984
CAS:<p>N-5984, a β3-adrenergic receptor agonist, is used potentially for the treatment of obesity, overactive bladder and type 2 diabetes.</p>Fórmula:C20H22ClNO5Pureza:98%Cor e Forma:SolidPeso molecular:391.85BMS-763534
CAS:<p>BMS-763534 is a potent antagonist of corticotropin-releasing factor/hormone receptor 1 (CRHR-1).</p>Fórmula:C18H21ClF2N4O3Cor e Forma:SolidPeso molecular:414.834-hydroxy Nebivolol hydrochloride
CAS:<p>4-Hydroxy Nebivolol, a primary metabolite of Nebivolol, results from the enzymatic hydroxylation of Nebivolol by the cytochrome P450 (CYP) isoform CYP2D6.</p>Fórmula:C22H25F2NO5HClCor e Forma:SolidPeso molecular:457.9BAY 60-2770
CAS:<p>BAY 60-2770: oral sGC activator, NO-independent, antifibrotic, boosts sGC activity.</p>Fórmula:C35H33F4NO5Cor e Forma:SolidPeso molecular:623.63JTE-952
CAS:<p>JTE-952: oral, selective Type II CSF-1R inhibitor, IC50 = 13 nM for CSF1R, 261 nM for TrkA, effective in mouse arthritis model.</p>Fórmula:C30H34N2O6Pureza:98%Cor e Forma:SolidPeso molecular:518.615(S)-Fluprostenol
CAS:<p>15(S)-Fluprostenol, an isomer of the FP receptor agonist fluprostenol, serves as a potential active metabolite of 15(S)-fluprostenol isopropyl ester. It can function as an agonist at FP receptors, though with lower potency compared to its 15(R) epimer, fluprostenol.</p>Fórmula:C23H29F3O6Cor e Forma:SolidPeso molecular:458.5Prostaglandin E2 serinol amide
CAS:<p>Prostaglandin E2 Serinol Amide acts as a weak inhibitor against the hydrolysis of [3H]2-oleoylglycerol, but it is non-hydrolyzable and cannot produce PGE2. Consequently, it is unable to inhibit leukotriene B4 biosynthesis, superoxide production, migration, and the release of antimicrobial peptides [1].</p>Fórmula:C23H39NO6Cor e Forma:SolidPeso molecular:425.566CP 154,526
CAS:<p>CP 154,526 is a selective CRF1 receptor antagonist (Ki = 2.7 nM). CP 154,526 blocks CRF-induced activation of adenylate cyclase and the HPA axis.</p>Fórmula:C23H32N4Cor e Forma:SolidPeso molecular:364.53RXFP1 receptor agonist-6
CAS:<p>RXFP1 receptor agonist-6 (Example 7) serves as an agonist for the RXFP1 receptor and effectively suppresses cAMP production in HEK293 cells that stably express</p>Fórmula:C38H32F5N3O7Cor e Forma:SolidPeso molecular:737.67MB-28767
CAS:<p>MB-28767 is an agonist of prostaglandin E2 (PGE2) receptor.</p>Fórmula:C22H30O5Cor e Forma:SolidPeso molecular:374.47SCH 206272
CAS:<p>SCH 206272 is a potent, orally active antagonist of tachykinin NK(1), NK(2), and NK(3) receptor.</p>Fórmula:C33H41Cl4N5O4Cor e Forma:SolidPeso molecular:713.52O-Arachidonoyl glycidol
CAS:<p>O-Arachidonoyl glycidol (compound 1), a 2-arachidonoylglycerol (2-AG) analog, effectively inhibits the hydrolysis of cytosolic 2-oleoylglycerol (2-OG) with an IC50 value of 4.5 µM, and also blocks 2-OG and anandamide hydrolysis in membrane fractions with IC50 values of 19 µM and 12 µM, respectively [1].</p>Fórmula:C23H36O3Cor e Forma:SolidPeso molecular:360.53MK-1421
CAS:<p>MK-1421 is a potent and selective sstr3 antagonist.</p>Fórmula:C27H24FN9O2Cor e Forma:SolidPeso molecular:525.54(-)-Isoproterenol hydrochloride
CAS:<p>(-)-Isoproterenol hydrochloride is used as a β-adrenergic receptor agonist in the treatment of bradycardia and as a bronchodilator.</p>Fórmula:C11H17NO3·CIHCor e Forma:SolidPeso molecular:247.72TGR5 agonist 3
CAS:<p>Compound 8, a cholic acid derivative, functions as a selective TGR5 agonist and exhibits an EC50 value of 5 μM [1].</p>Fórmula:C28H48O5Cor e Forma:SolidPeso molecular:464.68MIN-117
CAS:<p>MIN-117, a SSRI/5-HT receptor antagonist, is potentially used for the treatment of depression.</p>Fórmula:C25H26Cl3N3O4Pureza:98%Cor e Forma:SolidPeso molecular:538.85Glucagon receptor antagonists-3
CAS:<p>Glucagon receptor antagonist -3 is a highly effective glucagon receptor antagonist.</p>Fórmula:C22H30FNO2Pureza:98%Cor e Forma:SolidPeso molecular:359.48APJ receptor agonist 5
CAS:<p>Potent oral APJ agonist (EC 50:0.4 nM); improves cardiac function in HF, with good pharmacokinetics and safety.</p>Fórmula:C26H29N3O6Cor e Forma:SolidPeso molecular:479.52GSA-10
CAS:<p>GSA-10 is a potent Smoothened (Smo) receptor agonist with an EC50 of 1.2 μM.</p>Fórmula:C26H30N2O5Pureza:99.71%Cor e Forma:SolidPeso molecular:450.53KP496
CAS:<p>KP496 is a selective, dual antagonist for Thromboxane A2 receptor and Leukotriene D4 receptor.</p>Fórmula:C31H34ClN3O7S3Pureza:98%Cor e Forma:SolidPeso molecular:692.27ATP-γ-S tetrasodium
CAS:<p>Collagen, Type I, from bovine achilles tendon is a type I collagen extracted from bovine achilles tendon.</p>Fórmula:C10H12N5Na4O12P3SCor e Forma:SolidPeso molecular:611.17Siramesine Fumarate
CAS:<p>Siramesine Fumarate, a sigma receptor agonist, is used potentially for the treatment of generalized anxiety disorder.</p>Fórmula:C34H35FN2O5Pureza:98%Cor e Forma:SolidPeso molecular:570.652-Linoleoyl Glycerol
CAS:<p>2-Arachidonoyl glycerol (2-AG), a natural endocannabinoid ligand for the CB1 receptor, was isolated from porcine brain and characterized. Its congener, 2-linoleoyl glycerol (2-LG), which has a linoleoyl group instead of an arachidonoyl group, also exists alongside 2-AG in vivo. While 2-LG exhibits low intrinsic activity, it enhances the activity of 2-AG and other endocannabinoids through an "entourage" effect, attributed to the inhibition of breakdown and reuptake pathways that typically decrease endocannabinoid levels post-release.</p>Fórmula:C21H38O4Cor e Forma:SolidPeso molecular:354.5319-keto Fluprostenol
CAS:<p>9-Keto Fluprostenol, a potent analog of prostaglandin E2 (PGE2), features structural modifications aimed at enhancing its half-life and potency. It derives from Fluprostenol, a thoroughly researched, potent analog of PGF2α, primarily interacting with the FP receptor. The creation of 9-Keto Fluprostenol through the oxidation at C-9 of Fluprostenol suggests a high affinity for EP receptors, potentially functioning as a PGE2 agonist.</p>Fórmula:C23H27F3O6Cor e Forma:SolidPeso molecular:456.458(Rac)-Modipafant
CAS:<p>(Rac)-Modipafantis a PAFR antagonist that inhibits PAF-induced aggregation of washed platelets in rabbits.</p>Fórmula:C34H29ClN6O3Pureza:97.96% - 98.09%Cor e Forma:SolidPeso molecular:605.095-HT2A&5-HT2C agonist-1
CAS:<p>5-HT2A&5-HT2C agonist-1 (Example 2) is a dual-acting agent targeting the 5-HT2A and 5-HT2C receptors with respective IC50 values of 196 nM and 0.9 nM.</p>Fórmula:C14H20N2OPureza:98%Cor e Forma:SolidPeso molecular:232.32RXFP1 receptor agonist-1
CAS:<p>RXFP1 receptor agonist-1 (Example 2), an agonist of the RXFP1 receptor, suppresses cAMP production in HEK293 cells that constitutively express the human RXFP1,</p>Fórmula:C31H29F7N2O4Cor e Forma:SolidPeso molecular:626.56Tachykinin angatonist 1
CAS:<p>Tachykinin antagonist 1 is an antagonist of neurokinin receptors.</p>Fórmula:C24H35Cl2N5O3SPureza:98%Cor e Forma:SolidPeso molecular:544.54TA-1887
CAS:<p>TA-1887: Selective SGLT2 inhibitor, treats type 2 diabetes, lowers glucose in high-fat diet mice, boosts UGE, has good pharmacokinetics.</p>Fórmula:C24H26FNO5Cor e Forma:SolidPeso molecular:427.47TRAP-6-IN-1
CAS:<p>TRAP-6-IN-1 inhibits collagen/TRAP-6, IC50: 17.12/11.88 μM, blocks platelet aggregation.</p>Fórmula:C18H20O3Cor e Forma:SolidPeso molecular:284.35IIIM-8
CAS:<p>IIIM-8 is a melanogenesis inhibitor that suppresses pigment production in both in vitro and in vivo settings, exhibiting no cytotoxic effects on Human Adult</p>Fórmula:C14H17NO4Pureza:98%Cor e Forma:SolidPeso molecular:263.29UCB-35440
CAS:<p>UCB-35440, a 5-lipoxygenase inhibitor and a histamine H1 receptor antagonist, is used potentially for the treatment of dermatitis.</p>Fórmula:C31H34ClN5O4Cor e Forma:SolidPeso molecular:576.09NAS181
CAS:<p>rat 5-HT1B receptor antagonist</p>Fórmula:C21H34N2O10S2Pureza:98%Cor e Forma:SolidPeso molecular:538.63(Rac)-PF-4136309(1341224-83-6 Free base)
CAS:<p>PF-4136309 (INCB8761, PF-04136309) is a highly effective and selective oral CCR2 antagonist with good bioavailability, with an IC50 value of 5.2 nM for human</p>Fórmula:C29H31F3N6O3Cor e Forma:SolidPeso molecular:568.59Ro-24-0238
CAS:<p>Ro-24-0238 blocks PAF, curbing thromboxane creation and inflammation caused by PAF release.</p>Fórmula:C27H36N2O2Pureza:98%Cor e Forma:SolidPeso molecular:420.59BMS-764459
CAS:<p>BMS-764459 is a potent antagonist of corticotropin-releasing factor/hormone receptor 1 (CRHR-1).</p>Fórmula:C19H21F2N5O3Cor e Forma:SolidPeso molecular:405.4Saredutant
CAS:<p>Saredutant (SR 48968) is a selective neurokinin-2 (NK2) receptor antagonist that inhibits neurokinin A by blocking NK2 receptor, antidepressant and anxiolytic.</p>Fórmula:C31H35Cl2N3O2Pureza:99.12%Cor e Forma:SolidPeso molecular:552.54Bima SA
CAS:<p>Bimatoprost Serinol Amide (Bima SA), a prostaglandin analog, shows research potential for glaucoma [1].</p>Fórmula:C26H39NO6Cor e Forma:SolidPeso molecular:461.59I-287
CAS:<p>I-287 is a selective, orally active PAR2 inhibitor that functions as a negative allosteric modulator of Gαq and Gα12/13 activity and their downstream effectors.</p>Fórmula:C30H30ClFN4O4Cor e Forma:SolidPeso molecular:565.04NTNCB hydrochloride
CAS:<p>NTNCB hydrochloride is an antagonist of neuropeptide Y (NPY) Y5 receptor.</p>Fórmula:C25H34ClN3O4SPureza:98.38%Cor e Forma:SolidPeso molecular:508.07Celiprolol hydrochloride
CAS:Celiprolol hydrochloride (Selectrol) is a cardioselective beta-1 adrenergic antagonist that has intrinsic sympathomimetic activity.Fórmula:C20H33N3O4·HClCor e Forma:White Crystalline SolidPeso molecular:415.96ZINC49534341
CAS:<p>ZINC49534341 is a potent MRGPRX2 antagonist, exhibiting a K_i (inhibition constant) of 32 nM [1].</p>Fórmula:C12H9N3OS2Cor e Forma:SolidPeso molecular:275.35FTY720 (S)-Phosphate
CAS:<p>FTY720 (S)-Phosphate is an active FTY720 derivative modulating S1P receptors, preventing lymphocyte egress, enhancing barrier integrity, aiding immune research.</p>Fórmula:C19H34NO5PPureza:99.37%Cor e Forma:SolidPeso molecular:387.45GR 125487 sulfamate
CAS:<p>GR 125487 sulfamate is a 5-HT4 receptor antagonist.</p>Fórmula:C19H29FN4O8S2Pureza:98%Cor e Forma:SolidPeso molecular:524.582-Methyl-5-HT
CAS:<p>2-Methyl-5-HT (2-Methyl-5-hydroxytryptamine) is a potent and selective 5-HT3 receptor agonist with anti-depressive-like effects.</p>Fórmula:C11H14N2OPureza:97.18%Cor e Forma:SolidPeso molecular:190.24MRS3558
CAS:<p>MRS3558 is an agonist of A3 adenosine receptors.</p>Fórmula:C20H20Cl2N6O3Cor e Forma:SolidPeso molecular:463.32Hemopressin(rat) TFA
CAS:<p>Hemopressin(rat) TFA, a nonapeptide from hemoglobin α1-chain, selectively inhibits CB1 receptors and reduces inflammatory pain.</p>Fórmula:C55H78F3N13O14Cor e Forma:SolidPeso molecular:1202.28L-796568 dihydrochloride
CAS:<p>L-796568: potent β3 agonist (EC50 = 3.6 nM), >600-fold selectivity vs β1/β2, good oral bioavailability, long action.</p>Fórmula:C31H29Cl2F3N4O3S2Cor e Forma:SolidPeso molecular:697.625-HT3-In-1
CAS:<p>5-HT3-In-1 (compound example 8) exhabits with 5-HT3 inhibition activity.</p>Fórmula:C16H21ClN4O3Pureza:98%Cor e Forma:SolidPeso molecular:352.82Alclofenac
CAS:<p>Alclofenac (W-7320) aids chronic rheumatism by affecting acute phase proteins and L-tryptophan binding.</p>Fórmula:C11H11ClO3Pureza:99.89%Cor e Forma:SolidPeso molecular:226.66Prostaglandin D2-1-glyceryl ester
CAS:<p>Prostaglandin D2-1-glyceryl ester (PGD2-G; PGD2 2-glyceryl ester) is a chemical compound known for its significance in various biological processes. This compound, commonly referred to by its abbreviations PGD2-G or PGD2 2-glyceryl ester, plays a crucial role in the mediation of physiological functions.</p>Fórmula:C23H38O7Cor e Forma:SolidPeso molecular:426.55Ebopiprant
CAS:<p>Ebopiprant (OBE022) is a prostaglandin F2α (PGF2α) receptor antagonist that can be used to study obesity.</p>Fórmula:C30H34FN3O5S2Pureza:98.73%Cor e Forma:SolidPeso molecular:599.74A-349821
CAS:<p>A-349821 is an H3 receptor agonist radioligand.</p>Fórmula:C28H35F3N2O5Cor e Forma:SolidPeso molecular:536.59BMS-194449
CAS:<p>BMS-194449 is a full beta 3 agonist.</p>Fórmula:C24H24F4N2O6SCor e Forma:SolidPeso molecular:544.52CP-96021 hydrochloride
CAS:CP-96021 hydrochloride is a potent and orally active antagonist of leukotriene D4 (LTD4)/platelet activating factor receptor (Kis: 34 nM and 37 nM).Fórmula:C29H22ClFN4OSPureza:98%Cor e Forma:SolidPeso molecular:529.03EP2 receptor agonist 4
CAS:<p>EP2 receptor agonist 4 selectively activates the EP2 receptor with an efficacy concentration (EC50) of 43 nM [1].</p>Fórmula:C23H36O5Cor e Forma:SolidPeso molecular:392.53Vatinoxan hydrochloride
CAS:<p>Vatinoxan hydrochloride is an antagonist of the peripheral α2 adrenergic receptors.</p>Fórmula:C20H27ClN4O4SPureza:98%Cor e Forma:SolidPeso molecular:454.97GLP-1R agonist 12
CAS:GLP-1R agonist 12 (Compound 123) 是一种 GLP-1R 激动剂，能够用于研究糖尿病。Fórmula:C34H36N6O4Cor e Forma:SolidPeso molecular:592.69Leukotriene B4-3-aminopropylamide
CAS:<p>Leukotriene B4 (LTB4)-3-aminopropylamide is an analog of LTB4 that exhibits potent and selective binding to the BLT1 receptor with Ki values of 5.1 nM at BLT1 and 1,227 nM at BLT2, indicating its high affinity for BLT1 over BLT2. This compound's effects are mediated through interactions with two receptors, BLT1 and BLT2.</p>Fórmula:C23H40N2O3Cor e Forma:SolidPeso molecular:392.6E-6123
CAS:<p>E-6123 is an antagonist of platelet-activating factor (PAF) receptor.</p>Fórmula:C23H22ClN5OSPureza:98%Cor e Forma:SolidPeso molecular:451.97SKF 81297
CAS:<p>SKF 81297 is a selective and potent agonist for the dopamine D1 receptor [1].</p>Fórmula:C16H16ClNO2Pureza:98%Cor e Forma:SolidPeso molecular:289.76SRX246
CAS:<p>SRX246: potent CNS-penetrant V1a antagonist (Ki=0.3 nM), inactive at V1b/V2, negligible binding at 64 other receptor classes.</p>Fórmula:C42H49N5O5Pureza:98%Cor e Forma:SolidPeso molecular:703.87Prostaglandin D2 serinol amide
CAS:<p>Prostaglandin D2 serinol amide serves as a mild inhibitor against the hydrolysis of [3H]2-oleoylglycerol [1].</p>Fórmula:C23H39NO6Cor e Forma:SolidPeso molecular:425.566MNI-444
CAS:<p>MNI-444 is a PET radiotracer for adenosine 2A receptors.</p>Fórmula:C24H26FN9O2Cor e Forma:SolidPeso molecular:491.52LY108742
CAS:<p>LY108742 is an antagonist of 5-HT2.</p>Fórmula:C21H28N2O3Pureza:98%Cor e Forma:SolidPeso molecular:356.46AL 8810 methyl ester
CAS:<p>AL 8810 methyl ester, a prostaglandin F(2α) analog and receptor agonist, competitively antagonizes FP receptor agonist Fluprostenol effects. It lacks significant potency against TP, DP, EP(2), EP(4) receptor subtypes in cell lines [1].</p>Fórmula:C25H33FO4Cor e Forma:SolidPeso molecular:416.53PF-02575799
CAS:<p>PF-02575799 is an inhibitor of microsomal triglyceride transfer protein (MTP) (IC50: 0.77±0.29 nM).</p>Fórmula:C42H37FN4O4Pureza:98%Cor e Forma:SolidPeso molecular:680.77Befiradol
CAS:<p>Befiradol (NLX-112) is an agonist of 5-HT1A receptor.</p>Fórmula:C20H22ClF2N3OCor e Forma:SolidPeso molecular:393.86L 662025
CAS:<p>L 662025 is a PAF receptor antagonist.</p>Fórmula:C23H27N3O6Pureza:98%Cor e Forma:SolidPeso molecular:441.48β3-AR agonist 1
CAS:<p>β3-AR agonist 1 is a highly selective, and orally available agonist of β3-adrenergic receptor (EC50: 18 nM), being inactive to β1-, β2-, and α1A-AR (β1/β3, β2/</p>Fórmula:C22H28N4O4SPureza:98%Cor e Forma:SolidPeso molecular:444.55BMS-604992
CAS:<p>EX-1314 (BMS-604992) is a growth hormone secretagogue receptor (GHSR) agonist.</p>Fórmula:C24H32ClN7O5Cor e Forma:SolidPeso molecular:534.01ACT 335827
CAS:<p>ACT-335827: oral, brain-penetrant OXR1 selective antagonist; IC50: 6 nM (OXR1), 417 nM (OXR2); for neurological research.</p>Fórmula:C31H38N2O5Cor e Forma:SolidPeso molecular:518.64SC 51322
CAS:<p>SC 51322 is an EP1 prostanoid receptor antagonist.</p>Fórmula:C22H20ClN3O4SPureza:98%Cor e Forma:SolidPeso molecular:457.93SSTR5 antagonist 1
CAS:<p>SSTR5 antagonist 1: selective, oral SSTR5 blocker; IC50: 9.6 nM (human), 57 nM (mouse).</p>Fórmula:C28H34FN3O5Pureza:98%Cor e Forma:SolidPeso molecular:511.59GW405833 hydrochloride
CAS:<p>GW405833 hydrochloride, a potent and selective agonist of the cannabinoid-2 (CB2) receptor (EC 50 = 0.65 nM; maximum inhibition = 44.6%), exhibits significant antihyperalgesic effects in various rodent pain models [1] [2] [3].</p>Fórmula:C23H25Cl3N2O3Cor e Forma:SolidPeso molecular:483.82MK-0493
CAS:<p>MK-0493 is an effective and selective agonist of the melanocortin receptor 4 (MC4R). It also demonstrated significant reductions in energy intake.</p>Fórmula:C30H38ClF2N3O2Pureza:98%Cor e Forma:SolidPeso molecular:546.09Kisspeptin 234 TFA
CAS:<p>Kisspeptin 234 TFA is a 10-amino acid peptide analog of Kisspeptin 10 [1] that functions as an antagonist to the kisspeptin receptor (KISS1, GPR54).</p>Fórmula:C63H78N18O13·xC2HF3O2Cor e Forma:SolidPeso molecular:1409.43Fazamorexant
CAS:<p>Fazamorexant (YZJ-1139) is a powerful orexin receptor antagonist effective for insomnia research.</p>Fórmula:C25H25FN4O2Cor e Forma:SolidPeso molecular:432.49Carmoxirole hydrochloride
CAS:<p>Carmoxirole hydrochloride (EMD 45609 hydrochloride) is a selective dopamine D2 receptor agonist with antihypertensive activity in vivo.</p>Fórmula:C24H27ClN2O2Pureza:99.37% - 99.62%Cor e Forma:SolidPeso molecular:410.94
