GPCR/Proteína-G
Os inibidores de GPCR/proteínas G são compostos que têm como alvo os receptores acoplados a proteínas G (GPCRs) e as proteínas G associadas, que desempenham papéis críticos na transmissão de sinais do exterior para o interior das células. Esses inibidores são essenciais para estudar as vias de sinalização mediadas por GPCRs, que estão envolvidas em numerosos processos fisiológicos, incluindo percepção sensorial, resposta imunológica e neurotransmissão. Os inibidores de GPCR também são importantes no desenvolvimento de medicamentos, pois muitos agentes terapêuticos têm como alvo esses receptores. Na CymitQuimica, oferecemos uma ampla gama de inibidores de GPCR/proteínas G de alta qualidade para apoiar sua pesquisa em farmacologia, biologia celular e áreas afins.
Subcategorias de "GPCR/Proteína-G"
- Receptor 5-HT(942 produtos)
- Receptor de adenosina(242 produtos)
- Receptor adrenérgico(2.946 produtos)
- Receptor de Bombesina(30 produtos)
- Receptor de Bradicinina(59 produtos)
- CXCR(148 produtos)
- CaSR(32 produtos)
- Receptor de Canabinóides(195 produtos)
- Receptor de Dopamina(408 produtos)
- Receptor Endotelina(76 produtos)
- Receptor GNRH(73 produtos)
- GPCR19(31 produtos)
- GRK(31 produtos)
- GTPase(21 produtos)
- Receptor Glucagon(165 produtos)
- Hedgehog/Smoothened(44 produtos)
- Receptor de Histamina(359 produtos)
- Receptor LPA(21 produtos)
- Receptor de Melatonina(24 produtos)
- Receptor OX(40 produtos)
- Receptor opioide(298 produtos)
- PAFR(11 produtos)
- PKA(48 produtos)
- Receptor S1P(17 produtos)
- SGLT(30 produtos)
- Receptor Sigma(46 produtos)
Exibir 18 mais subcategorias
Foram encontrados 5360 produtos de "GPCR/Proteína-G"
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NCGC00229600
CAS:<p>NCGC00229600: Allosteric inverse TSHR agonist; blocks TSH and antibody TSHR activation; for Graves' disease research.</p>Fórmula:C30H29N3O3Pureza:99.31%Cor e Forma:SolidPeso molecular:479.57Apelin agonist 1
CAS:<p>Apelin agonist 1 is an orally available APJ receptor agonist with an EC50 value of 3.2 nM. Apelin agonist 1 is used in the study of cardiovascular disease.</p>Fórmula:C23H20FN5O5SPureza:97.69% - 99.07%Cor e Forma:SolidPeso molecular:497.5Mocravimod hydrochloride
CAS:<p>Mocravimod hydrochloride (KRP-203) is an effecitive and orally active agonist of sphingosine 1-phosphate receptor type 1(S1PR1).</p>Fórmula:C24H27Cl2NO3SPureza:90%Cor e Forma:SolidPeso molecular:480.45TM-N1324
CAS:<p>TM-N1324 is a GPR39 agonist; 280 nM potency without Zn2+, 9 nM with; similar effects on murine GPR39 (EC50s: 180 nM/5 nM).</p>Fórmula:C18H13ClFN7OPureza:99.88%Cor e Forma:SolidPeso molecular:397.79PSNCBAM-1
CAS:<p>PSNCBAM-1 (PSNCBAM 1) is a CB1 receptor negative allosteric modulator (EC50 = 0.1 μM) with hypophagic effects in vivo.</p>Fórmula:C22H21ClN4OPureza:99.86%Cor e Forma:SolidPeso molecular:392.88mPGES1-IN-3
CAS:<p>mPGES1-IN-3 is a potent and selective inhibitor of microsomal prostaglandin E2 synthase-1 (mPGES-1) .</p>Fórmula:C24H16ClF5N4O3Pureza:98%Cor e Forma:SolidPeso molecular:538.85Orvepitant maleate
CAS:<p>Orvepitant maleate, a selective NK-1 receptor antagonist (pKi 10.2), may treat depression and CRC; crosses the blood-brain barrier.</p>Fórmula:C35H39F7N4O6Pureza:98%Cor e Forma:SolidPeso molecular:744.7SB 258719
CAS:<p>SB 258719 is a selective antagonist of 5-HT7 receptor with pKi of 7.5.</p>Fórmula:C18H30N2O2SPureza:99.73%Cor e Forma:SolidPeso molecular:338.51OMDM-5
CAS:<p>OMDM-5 is a potent vanilloid receptor type 1 (TRPV1, EC50 = 75 nM) agonist, showing weak ligand activity at cannabinoid type 1 receptor (CB1, Ki=4.9 μM).</p>Fórmula:C26H44N2O3Pureza:99.73%Cor e Forma:SolidPeso molecular:432.64JNJ-19567470
CAS:<p>JNJ-19567470 is a selective, non-peptide CRF receptor 1 antagonist.</p>Fórmula:C22H27BrN4OCor e Forma:SolidPeso molecular:443.38LY-368975
CAS:<p>LY-368975 is a potent and selective inhibitor of the norepinephrine (NE) reuptake site. LY-368975 reduces food consumption in rodents.</p>Fórmula:C17H21NOSCor e Forma:SolidPeso molecular:287.42(+)-Fluprostenol
CAS:<p>(+)-Fluprostenol (AL-5848), an analogue of prostaglandin F2 alpha, is a prostaglandin F2α receptor PTGFR agonist and decreases the expression of Oviductal</p>Fórmula:C23H29F3O6Pureza:97.35%Cor e Forma:SolidPeso molecular:458.47GSK494581A
CAS:<p>GSK494581A is a GPR55 agonist and glycine transporter subtype 1 inhibitor.</p>Fórmula:C27H28F2N2O4SPureza:98%Cor e Forma:SolidPeso molecular:514.58FR-181877
CAS:<p>FR-181877: nonprostanoid PGI2 agonist, ADP-induced platelet aggregation inhibitor (IC50=0.081μM), orally bioavailable (56%), long half-life (4.3h) in rats.</p>Fórmula:C30H28N2O4Pureza:98%Cor e Forma:SolidPeso molecular:480.55PF 514273
CAS:<p>PF 514273 is a CB1 receptor antagonist.</p>Fórmula:C21H17Cl2F2N3O2Pureza:98%Cor e Forma:SolidPeso molecular:452.28Domesticine, (-)-
CAS:<p>Domesticine, (-)- is an antagonist of alpha-1D-adrenoceptor.</p>Fórmula:C19H19NO4Pureza:98%Cor e Forma:SolidPeso molecular:325.36Orexin receptor modulator-1
CAS:<p>Orexin Receptor Modulator-1 is a compound utilized in the study of various conditions including substance addiction, panic disorder, anxiety, post-traumatic</p>Fórmula:C23H22ClF5N6OCor e Forma:SolidPeso molecular:528.91Macimorelin acetate
CAS:<p>Macimorelin acetate (EP-1572) is an oral GHSR agonist for AGHD and CACS research.</p>Fórmula:C28H34N6O5Cor e Forma:SolidPeso molecular:534.61GS-6201
CAS:<p>GS-6201 (CVT-6883) is a selective antagonist of adenosine A2B receptor.</p>Fórmula:C21H21F3N6O2Pureza:99.74% - 99.78%Cor e Forma:SolidPeso molecular:446.43COR659
CAS:<p>COR659: suppresses alcohol/chocolate intake in rats; enhances GABAB receptor, blocks CB1 receptor.</p>Fórmula:C16H16ClNO3SPureza:99.75%Cor e Forma:SolidPeso molecular:337.82Sigma-1 receptor antagonist 3
CAS:<p>Sigma-1 receptor antagonist 3 is a more potent and selective antagonist of Sigma-1 (σ1) receptor (Ki = 1.14 nM) than σ2 receptor(Ki = 1239 nM).</p>Fórmula:C19H23ClFN3OPureza:99.95%Cor e Forma:SolidPeso molecular:363.86CP-122288
CAS:<p>CP-122288: potent, selective 5-HT1B/D/F agonist; inhibits plasma protein extravasation, neurogenic inflammation.</p>Fórmula:C16H23N3O2SPureza:98%Cor e Forma:SolidPeso molecular:321.44Ginkgolic acid 2-phosphate
CAS:<p>Ginkgolic acid 2-phosphate, a potent sphingosine 1-phosphate (S1P) agonist, induces ERK phosphorylation and interacts with S1P1 [1].</p>Fórmula:C22H37O6PCor e Forma:SolidPeso molecular:428.5cis-J-113863
CAS:<p>Cis-J-113863 is a competitive antagonist for the chemokine receptor 1 (CCR1), demonstrating inhibitory concentration 50 (IC50) values of 0.9 nM for human CCR1 receptors and 5.8 nM for mouse CCR1 receptors, respectively [1].</p>Fórmula:C30H37Cl2IN2O2Cor e Forma:SolidPeso molecular:655.44Veldoreotide TFA
CAS:<p>Veldoreotide (DG3173) TFA, a somatostatin analogue, effectively binds to and activates somatostatin receptors (SSTR) 2, 4, and 5. This compound demonstrates a higher efficacy in inhibiting growth hormone (GH) secretion in adenomas than Octreotide, showcasing its potential as a pain modulating agent [1].</p>Fórmula:C62H75F3N12O12Cor e Forma:SolidPeso molecular:1237.33Velagliflozin
CAS:<p>Velagliflozin is an orally available inhibitor of sodium-glucose cotransporter 2.</p>Fórmula:C23H25NO5Pureza:98%Cor e Forma:SolidPeso molecular:395.45Carmoxirole hydrochloride
CAS:<p>Carmoxirole hydrochloride (EMD 45609 hydrochloride) is a selective dopamine D2 receptor agonist with antihypertensive activity in vivo.</p>Fórmula:C24H27ClN2O2Pureza:99.37% - 99.62%Cor e Forma:SolidPeso molecular:410.94PF-03550096
CAS:<p>PF-03550096, an orally active synthetic cannabinoid (CB), selectively binds to peripheral CB2 receptors with a Ki value of 7.9 nM, demonstrating analgesic activity [1].</p>Fórmula:C19H28N4O4Cor e Forma:SolidPeso molecular:376.45PSB-1115 potassium salt
CAS:<p>PSB-1115 potassium salt, a selective A2B Adenosine Receptor antagonist, inhibits the 2,4,6-trinitrobenzenesulfonic acid (TNBS)-induced contraction inhibition of acetylcholine (ACh) [1].</p>Fórmula:C14H13KN4O5SCor e Forma:SolidPeso molecular:388.44AL 8810 methyl ester
CAS:<p>AL 8810 methyl ester, a prostaglandin F(2α) analog and receptor agonist, competitively antagonizes FP receptor agonist Fluprostenol effects. It lacks significant potency against TP, DP, EP(2), EP(4) receptor subtypes in cell lines [1].</p>Fórmula:C25H33FO4Cor e Forma:SolidPeso molecular:416.53JNJ-28583867
CAS:<p>JNJ-28583867 is an inhibitor of histamine H(3) receptor antagonist and serotonin reuptake.</p>Fórmula:C24H32N2O2SCor e Forma:SolidPeso molecular:412.59Y1R probe-1
CAS:<p>Compound 39, or Y1R probe-1, is a fluorescent probe for Neuropeptide Y Y1 Receptor used in cancer research.</p>Fórmula:C64H71F3N10O12Cor e Forma:SolidPeso molecular:1229.3RXFP1 receptor agonist-7
CAS:<p>RXFP1 receptor agonist-7 (Example 2) serves as an RXFP1 receptor agonist, effectively inhibiting cAMP production in HEK293 cells that stably express the human</p>Fórmula:C40H32F5N3O7Cor e Forma:SolidPeso molecular:761.69Hedgehog IN-2
CAS:<p>Hedgehog IN-2 (Compound 20) functions as an inhibitor of the Hedgehog signaling pathway, exhibiting an IC50 of <0.003 μM in C3H10T1/2 cells [1].</p>Fórmula:C24H22N4O2Cor e Forma:SolidPeso molecular:398.46PZ-1190
CAS:<p>PZ-1190, a multitarget ligand for serotonin and dopamine receptors, exhibits potential antipsychotic activity in rodents [1].</p>Fórmula:C27H30N4O2S2Pureza:98%Cor e Forma:SolidPeso molecular:506.68FPPQ
CAS:<p>FPPQ blocks 5-HT3 and 5-HT6 receptors (Ki: 0.9 & 3 nM) and may improve psychosis and cognition.</p>Fórmula:C21H19FN4O2SCor e Forma:SolidPeso molecular:410.46CCG-63808
CAS:<p>CCG-63808 is a reversible inhibitor of regulator of G-protein signaling (RGS) proteins.</p>Fórmula:C25H15FN4O2SPureza:90%Cor e Forma:SolidPeso molecular:454.48WLB-89462
CAS:<p>WLB-89462 (Compound 20c) is a selective σ2 receptor ligand with a K i of 13 nM, exhibiting neuroprotective properties and the ability to ameliorate Aβ peptide-</p>Fórmula:C21H29N5O3Pureza:98%Cor e Forma:SolidPeso molecular:399.49LY3154885
CAS:<p>LY3154885 is an orally active dopamine D1 receptor orthosteric modulator (PAM) that reduces the risk of drug-drug interactions (DDI).</p>Fórmula:C23H23Cl2N3O2Cor e Forma:SolidPeso molecular:444.35SC 34301
CAS:<p>SC 34301 (Enisoprost), a strong oral PGE1 analog, decreases bacterial translocation and increases burned mice survival.</p>Fórmula:C22H36O5Cor e Forma:SolidPeso molecular:380.52Encaleret
CAS:<p>Encaleret( JIT-305) is an antagonist of oral calcium-sensing receptor (CaSR), it is used for the treatment of osteoporosis.</p>Fórmula:C29H33ClFNO4Cor e Forma:SolidPeso molecular:514.03(S)-FTY720-phosphonate
CAS:<p>FTY720 (S)-Phosphate, an S1P receptor 1 (S1PR1) agonist, is utilized in studying acute inflammatory diseases, including acute lung injury.</p>Fórmula:C20H36NO4PPureza:98%Cor e Forma:SolidPeso molecular:385.48Amauromine
CAS:<p>Amauromine is a peripherally selective and potent cannabinoid receptor type 1 (CB1) receptor antagonist, a novel alkaloid with vasodilatory activity.</p>Fórmula:C32H36N4O2Cor e Forma:SolidPeso molecular:508.65CaSR antagonist-1
CAS:<p>CaSR Antagonist-1 is a potent inhibitor of the calcium-sensing receptor (CaSR) with an inhibitory concentration (IC50) of 50 nM, suitable for the investigation</p>Fórmula:C29H24FN3O2SPureza:98%Cor e Forma:SolidPeso molecular:497.58L-796568 free base
CAS:<p>L-796568 is a potent β3 agonist for obesity with 600x selectivity over β1/β2 receptors (EC50: 3.6 nM).</p>Fórmula:C31H27F3N4O3S2Cor e Forma:SolidPeso molecular:624.7BVFP
CAS:<p>BVFP is a PGRN-SORT1 inhibitor/SORT1 antagonist that binds to key residues 588-593 of PGRN,blocking PGRN-SORT1 binding and having potential for FTLD-TDP.</p>Fórmula:C13H8BrF3N2OPureza:98.74%Cor e Forma:SolidPeso molecular:345.12Indeloxazine hydrochloride
CAS:<p>Indeloxazine HCl: Serotonin releaser, NE reuptake inhibitor, NMDA antagonist; antidepressant that boosts acetylcholine in rats.</p>Fórmula:C14H18ClNO2Pureza:98%Cor e Forma:SolidPeso molecular:267.75S1p receptor agonist 2
CAS:<p>S1P5-selective agonist; less so for S1P1/S1P3; useful for CNS disorders.</p>Fórmula:C24H23ClN2O4Cor e Forma:SolidPeso molecular:438.9CP 154,526
CAS:<p>CP 154,526 is a selective CRF1 receptor antagonist (Ki = 2.7 nM). CP 154,526 blocks CRF-induced activation of adenylate cyclase and the HPA axis.</p>Fórmula:C23H32N4Cor e Forma:SolidPeso molecular:364.53TASP0376377
CAS:<p>TASP0376377 is a potent antagonist of CRTH2.</p>Fórmula:C25H16Cl2N2O4Cor e Forma:SolidPeso molecular:479.31L-736380
CAS:<p>L-736380, a CCK-B antagonist, reduces gastric acid (ID50: 0.064mg/kg) and blocks [(125)I]CCK-8S in mouse brains (ED50: 1.7mg/kg).</p>Fórmula:C25H29N9O2Cor e Forma:SolidPeso molecular:487.56GLP-1R agonist 3
CAS:<p>GLP-1R agonist 3 is a GLP-1R agonist, an imidazole derivative.GLP-1R agonist 3 can be used to study diabetes and obesity.</p>Fórmula:C31H28FN5O4Pureza:97.19%Cor e Forma:SolidPeso molecular:553.58LBT 999
CAS:<p>LBT 999 is used as a dopamine reuptake inhibitor.</p>Fórmula:C20H26FNO2Cor e Forma:SolidPeso molecular:331.42T 98475
CAS:<p>gonadotropin-releasing hormone (GnRH, LHRH) receptor antagonist,orally active</p>Fórmula:C37H37F2N3O4SPureza:98%Cor e Forma:SolidPeso molecular:657.77H4R antagonist 2
CAS:<p>H4R Antagonist 2, a potent Furo[3,2-d]pyrimidine derivative, serves as a histamine H4 receptor antagonist and holds potential for research into rheumatoid</p>Fórmula:C13H17N5OPureza:98%Cor e Forma:SolidPeso molecular:259.31Capeserod HCl
CAS:<p>Capeserod HCl, a 5-hydroxytriptamine 4 (5-HT4) receptor agonist, is used potentially for the treatment of Alzheimer's disease.</p>Fórmula:C23H26Cl2N4O4Pureza:98%Cor e Forma:SolidPeso molecular:493.38Frovatriptan
CAS:<p>Frovatriptan, potent 5-HT 1B/D agonist, shows high cerebroselectivity and efficacy for migraine with aura.</p>Fórmula:C14H17N3OCor e Forma:SolidPeso molecular:243.3AC-099 hydrochloride
CAS:<p>AC-099 hydrochloride is a full agonist of neuropeptide FF2 receptor NPFF2R and a partial agonist of neuropeptide FF1 receptor NPFF1R.</p>Fórmula:C9H9Cl2F3N4Pureza:99.86%Cor e Forma:SolidPeso molecular:301.1Uridine 5'-diphosphate
CAS:<p>Uridine 5'-diphosphate acts as a P2Y6 receptor agonist, exhibiting an EC50 value of 0.013 μM for the human P2Y6 receptor [1].</p>Fórmula:C9H14N2O12P2Pureza:98%Cor e Forma:SolidPeso molecular:404.16Talibegron hydrochloride
CAS:<p>Talibegron hydrochloride: β3 adrenoceptor agonist, pD2 3.72, relaxes rat arteries, reduces leptin in mice.</p>Fórmula:C18H22ClNO4Pureza:99.82%Cor e Forma:SolidPeso molecular:351.83GI 181771
CAS:<p>GI 181771 is an agonist of the cholecystokinin 1 receptor. GI 181771 can be used in studies about obesity.</p>Fórmula:C34H31N5O6Pureza:95.02%Cor e Forma:SolidPeso molecular:605.64Didesmethyl cariprazine
CAS:<p>Didesmethyl cariprazine, Cariprazine's active metabolite, treats schizophrenia/bipolar with D3/D2 affinity; half-life 1-3 weeks.</p>Fórmula:C19H28Cl2N4OPureza:99.52%Cor e Forma:SolidPeso molecular:399.36NMI 8739
CAS:<p>NMI 8739 (n-docosahexaenoyl dopamine) is an agonist of D2 autoreceptor.</p>Fórmula:C30H41NO3Pureza:98.51%Cor e Forma:SolidPeso molecular:463.65CGP-20712
CAS:<p>CGP-20712 is a selective β 1-adrenoceptor antagonist with an IC50 of 0.7 nM.</p>Fórmula:C23H25F3N4O5Pureza:99.40% - 99.58%Cor e Forma:SolidPeso molecular:494.46SB 216641 hydrochloride
CAS:<p>SB 216641 hydrochloride (SB-216641A) is a 5-HT1B/D receptor antagonist with anxiolytic properties.</p>Fórmula:C28H31ClN4O4Pureza:98.06% - 99.23%Cor e Forma:SolidPeso molecular:523.02PSB-603
CAS:<p>PSB-603 is a selective antagonist of Adenosine A2B receptor(Ki = 0.553 nM) with anti-inflammatory effects.</p>Fórmula:C24H25ClN6O4SPureza:97.13%Cor e Forma:SolidPeso molecular:529.010990CL
CAS:0990CL is an effective heterotrimer Gαi subunit specific inhibitor, which can interact with purified Go± in GDP-bound state, and can block α2AR mediated cAMPFórmula:C21H21N5Pureza:98.99%Cor e Forma:SolidPeso molecular:343.42Azelaprag
CAS:<p>Azelaprag (Example 263.0) is a candidate active molecule (EC50= 0.32 nM) for an apelin receptor agonist. treat nervous system diseases. High-Quality, Low-Cost!</p>Fórmula:C25H29N7O4SPureza:98.04% - >99.99%Cor e Forma:SolidPeso molecular:523.61Lotiglipron
CAS:<p>Lotiglipron (PF-07081532) is a GLP-1R agonist that lowers blood glucose and may be used in the study of type 2 diabetes mellitus (T2DM) and excess obesity.</p>Fórmula:C31H31ClN4O5Pureza:98.3%Cor e Forma:SolidPeso molecular:575.05(±)-Prenalterol
CAS:<p>(±)-Prenalterol (H 80/62) is an agonist of beta-2- and beta-1-adrenergic receptors and is used to study chronic congestive heart failure.</p>Fórmula:C12H19NO3Pureza:99.73%Cor e Forma:SolidPeso molecular:225.28α1 adrenoceptor-MO-1
CAS:<p>α1 adrenoceptor-MO-1 (S enantiomer) has affinity at alpha 1 adrenergic receptor with alphalytic activity and analgesic action.</p>Fórmula:C20H24ClN5OPureza:99.20% - 99.29%Cor e Forma:SolidPeso molecular:385.89CCR3 antagonist 1
CAS:<p>CCR3 antagonist 1 is a potent CCR3 antagonist, used for the research of inflammatory and immunologic diseases.</p>Fórmula:C19H21Cl2N3O4S2Pureza:98.28%Cor e Forma:SolidPeso molecular:490.42Deriglidole
CAS:<p>Deriglidole (SL 86-0715), an alpha2 receptor inhibitor, blocks colistin/Idazoxan but not prazosin/α2-adrenergic receptors.</p>Fórmula:C16H21N3Pureza:97.31% - 98.23%Cor e Forma:SolidPeso molecular:255.36GV150013
CAS:<p>GV150013 is an antagonist of cholecystokinin-2 (CCK2) receptor.</p>Fórmula:C33H34N4O3Pureza:99.93%Cor e Forma:SolidPeso molecular:534.65ST-1006
CAS:<p>ST-1006: histamine H4 agonist, pKi 7.94, anti-inflammatory, anti-pruritic, promotes basophil migration.</p>Fórmula:C16H20Cl2N6Pureza:98.87% - 99.96%Cor e Forma:SolidPeso molecular:367.28AS2717638
CAS:<p>AS2717638: oral LPA5 antagonist, IC50 38 nM, reduces PGF2α/PGE2/AMPA allodynia.</p>Fórmula:C25H25N3O5Pureza:99.23%Cor e Forma:SolidPeso molecular:447.48GW 833972A
CAS:<p>GW 833972A: selective CB2 agonist; reduces neural depolarization and citric acid cough in animals.</p>Fórmula:C18H14Cl2F3N5OPureza:99.93%Cor e Forma:SoildPeso molecular:444.24Calindol hydrochloride
CAS:<p>Calindol (hydrochloride) is a positive allosteric modulator (PAM) of calcimimetic calcium-sensing receptor (CaSR) with an EC50 of 132 nM.</p>Fórmula:C21H21ClN2Pureza:99.47%Cor e Forma:SolidPeso molecular:336.86Osemozotan HCl
CAS:<p>Osemozotan is a 5-HT1A receptor agonist potentially for the treatment of generalized anxiety disorder.</p>Fórmula:C19H22ClNO5Pureza:98.87% - 99.63%Cor e Forma:SolidPeso molecular:379.84Adomeglivant
CAS:<p>Adomeglivant (LY2409021) is a potent and selective glucagon receptor antagonist. Which is used in clinical trial for type 2 diabetes mellitus.</p>Fórmula:C32H36F3NO4Pureza:99.91%Cor e Forma:SolidPeso molecular:555.63PAOPA
CAS:<p>dopamine D2 receptor modulator</p>Fórmula:C11H18N4O3Pureza:>99.99%Cor e Forma:SolidPeso molecular:254.29Enerisant
CAS:<p>Enerisant (TS-091) is a histamine H3 receptor antagonist that promotes pro-cognitive effects and reverses scopolamine-induced cognitive deficits.</p>Fórmula:C22H30N4O3Pureza:99.7%Cor e Forma:SoildPeso molecular:398.50LGD-6972
CAS:<p>LGD-6972 is an antagonist of glucagon receptor.</p>Fórmula:C43H46N2O5SPureza:98.8% - 99.62%Cor e Forma:SolidPeso molecular:702.9SAG 21k
CAS:<p>SAG 21k is an orally bioactive and potent Hedgehog signaling activator that crosses the blood-brain barrier for the study of cartilage regeneration.</p>Fórmula:C29H28ClF2N3O2SPureza:99.51%Cor e Forma:SolidPeso molecular:556.07WAY-639889
CAS:<p>WAY-639889 is a small molecule compound with selective and potent inhibitory effects on neuropeptide Y-5 receptors.</p>Fórmula:C25H27N5OPureza:99.73%Cor e Forma:SolidPeso molecular:413.51WAY-607695
CAS:<p>WAY-607695 is a potential 5-HT1A receptor agonist.</p>Fórmula:C13H12FNO2Pureza:99.82%Cor e Forma:SolidPeso molecular:233.24Anti-inflammatory agent 49
CAS:<p>Compound SC9, an anti-inflammatory agent, serves as a potent and selective inhibitor of the Drp1-Fis1 interaction, mitigating FIS1-mediated mitochondrial</p>Fórmula:C21H22N8O3SPureza:99.56% - 99.74%Cor e Forma:SolidPeso molecular:466.52OPC-28326
CAS:<p>OPC-28326: an α2-adrenergic blocker; dilates blood vessels; inhibits α2A/B/C receptors with Ki 2040/285/55 nM.</p>Fórmula:C26H35N3O2Pureza:99.79%Cor e Forma:SolidPeso molecular:421.58Selvigaltin
CAS:<p>Selvigaltin (GB1211) is a Gal-3 inhibitor with potential anticancer activity. Selvigaltin is used in the study of cirrhosis and cancer.</p>Fórmula:C19H16BrF3N4O4SPureza:99.49%Cor e Forma:SolidPeso molecular:533.32A2B receptor antagonist 1
CAS:<p>A2B receptor antagonist 1 (EXAMPLE 9B) is a potent A2B adenosine receptor antagonist.</p>Fórmula:C21H24N6O2Pureza:99.53%Cor e Forma:SolidPeso molecular:392.45AY 77
CAS:<p>AY 77: Potent, selective PAR2 agonist, favors Ca2+ (ec50=40nM) & ERK1/2 (ec50=2μM), boosts breast cancer cell migration.</p>Fórmula:C21H32N4O4Pureza:99.7%Cor e Forma:SolidPeso molecular:404.5Clazosentan
CAS:<p>Clazosentan (Ro 61-1790) is a selective ET_A receptor antagonist that inhibits ET-1 vasoconstriction and prevents cerebral vasospasm.</p>Fórmula:C25H23N9O6SPureza:95.39% - >99.99%Cor e Forma:SolidPeso molecular:577.57Vidupiprant
CAS:<p>Vidupiprant (AMG 853) is an effective dual antagonist of CRTH2 and prostanoid D receptor with IC50s of 8 nM and 35 nM in human plasma.</p>Fórmula:C28H27Cl2FN2O6SPureza:98.88%Cor e Forma:SolidPeso molecular:609.49TAK-441
CAS:<p>TAK-441: oral Hedgehog signal blocker, potent anticancer, IC50=4.4 nM, reduces Gli1 mRNA & tumor growth.</p>Fórmula:C28H31F3N4O6Pureza:99.82%Cor e Forma:SolidPeso molecular:576.56Selatogrel
CAS:<p>Selatogrel (ACT-246475) is a P2Y12 receptor antagonist with antithrombotic activity and inhibits platelet aggregation.</p>Fórmula:C28H39N6O8PPureza:98.43%Cor e Forma:SolidPeso molecular:618.62Ertugliflozin L-pyroglutamic acid
CAS:<p>Ertugliflozin is a potent oral hSGLT2 inhibitor (IC50: 0.877 nM) for type 2 diabetes treatment studies.</p>Fórmula:C27H32ClNO10Pureza:99.88% - 99.94%Cor e Forma:SolidPeso molecular:566K777
CAS:<p>K777: Oral cysteine protease inhibitor, CYP3A4 blocker (IC50=60 nM), CCR4 antagonist, anti-Trypanosoma cruzi, antiviral, halts EBOV/SARS-CoV entry (IC50<1 nM).</p>Fórmula:C32H38N4O4SPureza:98.43% - 99.14%Cor e Forma:SolidPeso molecular:574.73INT-777
CAS:<p>INT-777 (S-EMCA) is a potent TGR5 agonist with an EC50 of 0.82 μM.</p>Fórmula:C27H46O5Pureza:99.89%Cor e Forma:SolidPeso molecular:450.65SR 142948
CAS:<p>SR 142948 is a neurotensin (NT) receptor antagonist.</p>Fórmula:C39H51N5O6Pureza:98%Cor e Forma:SolidPeso molecular:685.85PSB 1115
CAS:<p>PSB 1115 is an A2B receptor antagonist and can counteract the inhibitory effect of NECA.</p>Fórmula:C14H14N4O5SPureza:98.69% - >99.99%Cor e Forma:SolidPeso molecular:350.35
