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GPCR/Proteína-G

GPCR/Proteína-G

Os inibidores de GPCR/proteínas G são compostos que têm como alvo os receptores acoplados a proteínas G (GPCRs) e as proteínas G associadas, que desempenham papéis críticos na transmissão de sinais do exterior para o interior das células. Esses inibidores são essenciais para estudar as vias de sinalização mediadas por GPCRs, que estão envolvidas em numerosos processos fisiológicos, incluindo percepção sensorial, resposta imunológica e neurotransmissão. Os inibidores de GPCR também são importantes no desenvolvimento de medicamentos, pois muitos agentes terapêuticos têm como alvo esses receptores. Na CymitQuimica, oferecemos uma ampla gama de inibidores de GPCR/proteínas G de alta qualidade para apoiar sua pesquisa em farmacologia, biologia celular e áreas afins.

Subcategorias de "GPCR/Proteína-G"

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Foram encontrados 5360 produtos de "GPCR/Proteína-G"

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  • L-741626
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    L-741626

    CAS:
    <p>L-741626 (3-(4-(4-Chlorophenyl-4-hydroxypiperidino)methyl)indole) is a selective antagonist of D2 dopamine receptor (Ki: 2.4, 100, and 220 nM for human D2, D3</p>
    Fórmula:C20H21ClN2O
    Pureza:98.57%
    Cor e Forma:Solid
    Peso molecular:340.85

    Ref: TM-T15686

  • Hydroxyzine Pamoate
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    Hydroxyzine Pamoate

    CAS:
    <p>Hydroxyzine Pamoate (Bobsule) is a histamine H1 receptor antagonist that is effective in the treatment of chronic urticaria and histamine-mediated pruritus.</p>
    Fórmula:C44H43ClN2O8
    Pureza:99.49%
    Cor e Forma:Solid
    Peso molecular:763.27

    Ref: TM-T0053

  • RS102895 hydrochloride
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    RS102895 hydrochloride

    CAS:
    <p>RS102895 hydrochloride is a potent antagonist of CCR2(IC50 of 360 nM).</p>
    Fórmula:C21H22ClF3N2O2
    Pureza:98.95%
    Cor e Forma:Solid
    Peso molecular:426.86

    Ref: TM-T12773

  • Carvedilol EP IMpurity E
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    Carvedilol EP IMpurity E

    CAS:
    <p>Carvedilol EP IMpurity E (Carvedilol USP E) is used as a pharmaceutical intermediate.</p>
    Fórmula:C9H14ClNO2
    Pureza:99.53%
    Cor e Forma:White To Almost White Solid Crystalline
    Peso molecular:203.666

    Ref: TM-T1698

  • Flopropione
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    Flopropione

    CAS:
    <p>Flopropione (Phloropropiophenone), a spasmolytic or antispasmodic agent, is used as a 5-HT1A receptor antagonist.</p>
    Fórmula:C9H10O4
    Pureza:99.93%
    Cor e Forma:Solid
    Peso molecular:182.17

    Ref: TM-T0525

  • Duloxetine hydrochloride
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    Duloxetine hydrochloride

    CAS:
    <p>Duloxetine hydrochloride is an SNRI used for depression, anxiety, and pain in diabetes and fibromyalgia.</p>
    Fórmula:C18H20ClNOS
    Pureza:99.93% - >99.99%
    Cor e Forma:White Or White Crystalline Powder
    Peso molecular:333.88

    Ref: TM-T1471

  • Tropanserin
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    Tropanserin

    CAS:
    <p>Tropanserin (MDL 72422) is a 5-hydroxytryptamine receptor antagonist with anxiolytic activity that is used to treat depression and cognitive impairment.</p>
    Fórmula:C17H23NO2
    Pureza:99.74%
    Cor e Forma:Solid
    Peso molecular:273.37

    Ref: TM-T8451

  • Pafenolol
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    Pafenolol

    CAS:
    <p>Pafenolol is a P-glycoprotein modulator with a Ki value of 5.5 µM. pafenolol is an orally available and selective beta-adrenergic receptor antagonist.</p>
    Fórmula:C18H31N3O3
    Pureza:98.33%
    Cor e Forma:Solid
    Peso molecular:337.46

    Ref: TM-T68124

  • mPGES-1/sEH-IN-1
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    mPGES-1/sEH-IN-1

    <p>mPGES-1/sEH-IN-1 (compound 1f) is an sEH inhibitor with an IC50 value of 5 μM. It also exhibits antitumor activity by inhibiting mPGES-1, with an IC50 value of 25 µM.</p>
    Fórmula:C20H16F3N3O2
    Cor e Forma:Solid
    Peso molecular:387.355

    Ref: TM-T204923

  • (D-Arg8)-Inotocin
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    (D-Arg8)-Inotocin

    CAS:
    <p>'(D-Arg8)-Inotocin is a potent, selective, and competitive antagonist of the vasopressin receptor (V 1a R), exhibiting a binding affinity (K i) of 1.3 nM.</p>
    Fórmula:C39H68N14O11S2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:973.17

    Ref: TM-T80138

  • PF-4363467
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    PF-4363467

    CAS:
    <p>PF-4363467 is a dopamine D3/D2 receptor antagonist that reduces opioid-seeking behavior without the side effects associated with D2 receptors. It has a Ki value of 3.1 nM for D3R and 692 nM for D2R.</p>
    Fórmula:C22H30N2O3S
    Cor e Forma:Solid
    Peso molecular:402.55

    Ref: TM-T203495

  • Logotipo do CymitQuimica
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    CCZ01048 TFA

    CCZ01048 TFA, α-MSH analog, binds MC1R with 0.31 nM affinity, internalizes in melanoma cells, and is stable for melanoma PET imaging.
    Fórmula:C73H106F3N21O18
    Cor e Forma:Solid
    Peso molecular:1622.75

    Ref: TM-T76072L

  • 17-TFM-PGF1α
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    17-TFM-PGF1α

    CAS:
    <p>17-TFM-PGF1α (Compound 8) is a saturated prostaglandin analog. It exhibits a high affinity and receptor selectivity for the human prostaglandin F receptor (hFP receptor), with an EC50 of 85 nM.</p>
    Fórmula:C24H35F3O5
    Cor e Forma:Solid
    Peso molecular:460.53

    Ref: TM-T203103

  • [Deamino-Pen1,Val4,D-Arg8]-vasopressin
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    [Deamino-Pen1,Val4,D-Arg8]-vasopressin

    CAS:
    <p>[Deamino-Pen1,Val4,D-Arg8]-vasopressin (AVP-A) is an antagonist of arginine-vasopressin (AVP).</p>
    Fórmula:C48H69N13O11S2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:1068.27

    Ref: TM-T83501

  • PAF C-18
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    PAF C-18

    CAS:
    <p>PAF C-18 is a natural phospholipid molecule belonging to the platelet-activating factor (PAF) family,, involved in hemostasis and thrombosis by binding to PAFR.</p>
    Fórmula:C28H58NO7P
    Pureza:>99.99%
    Cor e Forma:Solid
    Peso molecular:551.74

    Ref: TM-T36763

  • BAY-6672
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    BAY-6672

    CAS:
    <p>BAY-6672 is, a selective,oral, highly potent human prostaglandin F (FP) receptor antagonist, exerts antifibrotic effects by inhibiting PGF₂α activity.</p>
    Fórmula:C26H27BrClN3O3
    Pureza:99.51%
    Cor e Forma:Solid
    Peso molecular:544.87

    Ref: TM-T39760

  • Logotipo do CymitQuimica
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    AD353

    <p>AD353 is a selective sigma-1 receptor ligand. It demonstrates high efficacy in models of capsaicin-induced allodynia and PGE2-induced mechanical hyperalgesia. Additionally, AD353 exhibits favorable pharmacokinetic properties.</p>
    Fórmula:C23H30N2O2
    Cor e Forma:Solid
    Peso molecular:366.5

    Ref: TM-T203662

  • 4-hydroxy DiPT hydrochloride
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    4-hydroxy DiPT hydrochloride

    CAS:
    <p>4-hydroxy DiPT (hydrochloride) is a 5-HT2A agonist that can induce head twitch response (HTR) in mice, indicating its hallucinogenic potential. This compound holds promise for research into hallucinogens.</p>
    Fórmula:C16H25ClN2O
    Cor e Forma:Solid
    Peso molecular:296.84

    Ref: TM-T203093

  • Logotipo do CymitQuimica
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    Petrelintide acetate

    <p>Petrelintide (ZP8396) acetate is an amylin analog with potential for weight reduction, suitable for diabetes research.</p>
    Fórmula:C185H305N49O61·xC2H4O2
    Cor e Forma:Solid
    Peso molecular:4191.69 (free base)

    Ref: TM-TP3039

  • Δ8-THC methyl ether
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    Δ8-THC methyl ether

    CAS:
    <p>Δ8-THC methyl ether (compound 3) demonstrates a strong docking score of -10.167 kcal/mol for the CB2 receptor. Additionally, Δ8-THC methyl ether exhibits antinociceptive activity in mice.</p>
    Fórmula:C22H32O2
    Cor e Forma:Solid
    Peso molecular:328.49

    Ref: TM-T203182