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GPCR/Proteína-G

GPCR/Proteína-G

Os inibidores de GPCR/proteínas G são compostos que têm como alvo os receptores acoplados a proteínas G (GPCRs) e as proteínas G associadas, que desempenham papéis críticos na transmissão de sinais do exterior para o interior das células. Esses inibidores são essenciais para estudar as vias de sinalização mediadas por GPCRs, que estão envolvidas em numerosos processos fisiológicos, incluindo percepção sensorial, resposta imunológica e neurotransmissão. Os inibidores de GPCR também são importantes no desenvolvimento de medicamentos, pois muitos agentes terapêuticos têm como alvo esses receptores. Na CymitQuimica, oferecemos uma ampla gama de inibidores de GPCR/proteínas G de alta qualidade para apoiar sua pesquisa em farmacologia, biologia celular e áreas afins.

Subcategorias de "GPCR/Proteína-G"

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Foram encontrados 5352 produtos de "GPCR/Proteína-G"

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  • Luseogliflozin hydrate
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    Luseogliflozin hydrate

    CAS:
    <p>Luseogliflozin hydrate: SGLT2 inhibitor, IC50 2.26 nM, oral, for type 2 diabetes research.</p>
    Fórmula:C23H32O7S
    Cor e Forma:Solid
    Peso molecular:452.56

    Ref: TM-T38539

  • 11β-Prostaglandin E2
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    11β-Prostaglandin E2

    CAS:
    <p>11β-PGE2 is the C-11 epimer of PGE2.</p>
    Fórmula:C20H32O5
    Cor e Forma:Solid
    Peso molecular:352.47

    Ref: TM-T36144

  • (+)-Oxypeucedanin methanolate
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    (+)-Oxypeucedanin methanolate

    CAS:
    <p>(+)-Oxypeucedanin methanolate (compound 9) is a natural compound that inhibits prostaglandin E2 production [1].</p>
    Fórmula:C17H18O6
    Cor e Forma:Solid
    Peso molecular:318.32

    Ref: TM-T75620

  • Logotipo do CymitQuimica
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    PG106 TFA

    <p>PG106 TFA is a potent hMC3 antagonist (IC50=210 nM), inactive at hMC4 (EC50=9900 nM) and hMC5 receptors.</p>
    Fórmula:C53H70F3N13O11
    Cor e Forma:Solid
    Peso molecular:1122.2

    Ref: TM-T75848

  • Logotipo do CymitQuimica
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    GHRF, porcine

    CAS:
    <p>GHRF, porcine, a growth hormone releasing factor (GHRF) peptide (porcine), binds to the growth hormone secretagogue receptor (GHSR), thereby inducing the</p>
    Fórmula:C219H365N73O66S
    Cor e Forma:Solid
    Peso molecular:5108.76

    Ref: TM-T76318

  • Logotipo do CymitQuimica
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    α-Helical CRF(9-41) TFA

    <p>α-Helical CRF(9-41) TFA acts as a competitive antagonist for the CRF2 receptor, possessing a binding constant (K B) of approximately 100 nM.</p>
    Fórmula:C168H275F3N46O55S2
    Cor e Forma:Solid
    Peso molecular:3940.42

    Ref: TM-T75891

  • Corazonin
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    Corazonin

    CAS:
    <p>Corazonin, a neuropeptide in insects, regulates caste identity and behavior, mainly in workers/foragers.</p>
    Fórmula:C62H83N17O19
    Cor e Forma:Solid
    Peso molecular:1370.42

    Ref: TM-T76183

  • Logotipo do CymitQuimica
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    dCNP

    <p>dCNP binds to NPR-B/C receptors (NPR-B/C receptor), initiating the cGMP signaling pathway and regulating vascular function. It exhibits anti-hypoxic effects by downregulating hypoxia-related genes such as HIF1α and HIF2α. Additionally, dCNP inhibits tumor stroma induction, demonstrating antifibrotic properties. It also enhances immune response by upregulating CTL, NK cells, and conventional type 1 dendritic cells in tumors.</p>
    Fórmula:C141H248N38O36S3
    Cor e Forma:Solid
    Peso molecular:3147.91

    Ref: TM-TP3063

  • Neurokinin Receptor (393-407), rat
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    Neurokinin Receptor (393-407), rat

    CAS:
    <p>Rat NK1R fragment (393-407) binds SP, enabling endocytosis and plasma membrane recycling; key in neurogenic inflammation research.</p>
    Fórmula:C72H113N17O26S2
    Cor e Forma:Solid
    Peso molecular:1696.9

    Ref: TM-T76429

  • Logotipo do CymitQuimica
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    [His1,Nle27] GHRF (1-32), amide, human

    CAS:
    <p>[His1,Nle27] GHRF (1-32), amide, human is a potent GHRH analog with high GHRHR affinity.</p>
    Fórmula:C159H265N51O46
    Cor e Forma:Solid
    Peso molecular:3627.12

    Ref: TM-T76317

  • ANP [Des18-22] 4-23 amide rat
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    ANP [Des18-22] 4-23 amide rat

    CAS:
    <p>ANP [Des18-22] 4-23 amide rat is a peptide fragment of rat atrial natriuretic peptide (ANP) that specifically binds to NPR-C.</p>
    Fórmula:C64H107N25O19S2
    Cor e Forma:Solid
    Peso molecular:1594.82

    Ref: TM-TP3030

  • AZ7976
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    AZ7976

    CAS:
    <p>AZ7976 (Compound 42), a potent and highly selective agonist for Relaxin Family Peptide Receptor 1 (RXFP1) with a pEC 50 value greater than 10.5, operates through an allosteric mechanism to enhance RXFP1's cAMP signaling, which physiologically elevates heart rate. This property makes AZ7976 a valuable tool in cardiovascular disease research [1].</p>
    Fórmula:C30H33F7N2O6S
    Cor e Forma:Solid
    Peso molecular:682.65

    Ref: TM-T85783

  • Logotipo do CymitQuimica
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    γ-1-Melanocyte Stimulating Hormone (MSH), amide

    <p>γ-1-Melanocyte Stimulating Hormone (MSH), amide, a peptide consisting of 11 amino acids, plays a critical role in regulating sodium (Na+) balance and blood</p>
    Fórmula:C72H97N21O14S
    Cor e Forma:Solid
    Peso molecular:1512.9

    Ref: TM-T75971

  • Logotipo do CymitQuimica
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    FTSDVSKQMEEEAVRLFIEWLKNGGPSSGAPPPS

    <p>FTSDVSKQMEEEAVRLFIEWLKNGGPSSGAPPPS is an Exendin-4 peptide derivative.</p>
    Cor e Forma:Solid
    Peso molecular:3692.15

    Ref: TM-T75859

  • Logotipo do CymitQuimica
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    PACAP (1-38) free acid TFA

    <p>PACAP (1-38) free acid TFA, an endogenous neuropeptide, effectively enhances antral motility and somatostatin secretion, while concurrently suppressing gastrin</p>
    Cor e Forma:Odour Solid

    Ref: TM-T81571

  • Logotipo do CymitQuimica
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    PAMP-12 (unmodified) (TFA)

    <p>PAMP-12 (unmodified) TFA, an endogenous peptide and potent MRGPRX2 (MrgX2) agonist (EC50=20-50 nM), induces hypotension by inhibiting catecholamine secretion</p>
    Fórmula:C79H119F3N24O17
    Cor e Forma:Solid
    Peso molecular:1733.94

    Ref: TM-T80080

  • Logotipo do CymitQuimica
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    PG-931 TFA

    <p>PG-931 TFA, a potent MC4 receptor agonist (IC50 0.58 nM), excels in selectivity and helps reverse hemorrhagic shock in vivo.</p>
    Fórmula:C61H86F3N15O13
    Cor e Forma:Solid
    Peso molecular:1294.42

    Ref: TM-T75847

  • (2R,2R)-PF-07258669
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    (2R,2R)-PF-07258669

    CAS:
    <p>(2R,2R)-PF-07258669' is an antagonist for the MC4R (melanocortin 4 receptor), primarily studied for its role in regulating appetite and energy expenditure.</p>
    Fórmula:C25H27FN6O2
    Cor e Forma:Solid
    Peso molecular:462.52

    Ref: TM-T88749

  • Logotipo do CymitQuimica
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    Melanostatin, frog

    CAS:
    <p>Melanostatin, frog, is an inhibitor of α-melanocyte-stimulating hormone (α-MSH) release, with an IC50 of 60 nM [1] [2].</p>
    Fórmula:C189H285N53O57S
    Cor e Forma:Solid
    Peso molecular:4243.67

    Ref: TM-TP2603

  • Logotipo do CymitQuimica
    Targetmol
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    α-CGRP(human) TFA

    <p>α-CGRP(human) TFA is a 37-amino acid regulatory neuropeptide that is extensively located within the central and peripheral nervous system, functioning as a</p>
    Fórmula:C165H268F3N51O51S2
    Cor e Forma:Solid
    Peso molecular:3903.33

    Ref: TM-T75788