CymitQuimica logo
GPCR/Proteína-G

GPCR/Proteína-G

Os inibidores de GPCR/proteínas G são compostos que têm como alvo os receptores acoplados a proteínas G (GPCRs) e as proteínas G associadas, que desempenham papéis críticos na transmissão de sinais do exterior para o interior das células. Esses inibidores são essenciais para estudar as vias de sinalização mediadas por GPCRs, que estão envolvidas em numerosos processos fisiológicos, incluindo percepção sensorial, resposta imunológica e neurotransmissão. Os inibidores de GPCR também são importantes no desenvolvimento de medicamentos, pois muitos agentes terapêuticos têm como alvo esses receptores. Na CymitQuimica, oferecemos uma ampla gama de inibidores de GPCR/proteínas G de alta qualidade para apoiar sua pesquisa em farmacologia, biologia celular e áreas afins.

Subcategorias de "GPCR/Proteína-G"

Exibir 18 mais subcategorias

Foram encontrados 5352 produtos de "GPCR/Proteína-G"

Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
produtos por página.
  • Logotipo do CymitQuimica
    Targetmol
    + Info

    D4R antagonis-2

    <p>Potent D4R antagonist-2: selective, IC50=6.52 μM, good in vitro PK and brain penetration, potential for Parkinson's research.</p>
    Fórmula:C21H23ClF2N2O2
    Cor e Forma:Solid
    Peso molecular:408.87

    Ref: TM-T62054

  • Rivenprost
    Targetmol
    + Info

    Rivenprost

    CAS:
    <p>Rivenprost, selective EP4 agonist (Ki: 0.7 nM), promotes bone growth, osteoblast differentiation, and aids wound healing.</p>
    Fórmula:C24H34O6S
    Cor e Forma:Solid
    Peso molecular:450.59

    Ref: TM-T36080

  • K-14585
    Targetmol
    + Info

    K-14585

    CAS:
    <p>K-14585 blocks PAR(2), reduces NFkappaB activity, and IL-8 response, but alone can boost IL-8.</p>
    Fórmula:C51H56Cl2N8O4
    Cor e Forma:Solid
    Peso molecular:915.95

    Ref: TM-T27708

  • HU-308
    Targetmol
    + Info

    HU-308

    CAS:
    <p>HU-308, a synthetic cannabinoid analogue, is a highly selective agonist of the CB2 receptor. It demonstrates an affinity for the CB2 receptor that is over 440 times greater than its affinity for the CB1 receptor, which are predominantly found in immune cells. This compound plays a crucial role in modulating the immunosuppressive effects of the endocannabinoid system (ECS). Additionally, HU-308 possesses anti-inflammatory and neuroprotective properties, and it regulates the function of microglia. Its potential applications include research into neuroinflammation and retinal diseases.</p>
    Fórmula:C27H42O3
    Cor e Forma:Solid
    Peso molecular:414.62

    Ref: TM-T88361

  • Remlifanserin
    Targetmol
    + Info

    Remlifanserin

    CAS:
    <p>Remlifanserin is a potent inverse agonist of the serotonin receptor (5-HT2A).</p>
    Fórmula:C24H29F2N3O2
    Cor e Forma:Solid
    Peso molecular:429.50

    Ref: TM-T201055

  • CP-199330
    Targetmol
    + Info

    CP-199330

    CAS:
    <p>CP-199330: non-toxic alternative to Zafirlukast &amp; Pranlukast, blocks cysteyl LT1 receptors.</p>
    Fórmula:C28H24ClF3N2O6S
    Cor e Forma:Solid
    Peso molecular:609.01

    Ref: TM-T31043

  • BIIE-0246 HCl
    Targetmol
    + Info

    BIIE-0246 HCl

    CAS:
    <p>BIIE-0246: A potent, non-peptide Y2 receptor antagonist; &gt;650-fold more selective than Y1, Y4, Y5.</p>
    Fórmula:C49H59Cl2N11O6
    Cor e Forma:Solid
    Peso molecular:968.97

    Ref: TM-T69621

  • H3R antagonist 1
    Targetmol
    + Info

    H3R antagonist 1

    CAS:
    <p>H3R-IN-1 is an effective inverse agonist of the histamine receptor 3 (H3R).</p>
    Fórmula:C19H23N3O3
    Cor e Forma:Solid
    Peso molecular:341.4

    Ref: TM-T200063

  • MSX-3
    Targetmol
    + Info

    MSX-3

    CAS:
    <p>MSX-3 is an antagonist of the A2A adenosine receptor and a prodrug of MSX-2.</p>
    Fórmula:C21H23N4Na2O7P
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:520.389

    Ref: TM-T25841

  • GLP-1 receptor agonist 11
    Targetmol
    + Info

    GLP-1 receptor agonist 11

    CAS:
    <p>GLP-1 Receptor Agonist 11 (compound 3) acts as an effective agonist for the GLP Receptor, finding use in research related to conditions like diabetes and non-alc. fatty liver disease [1].</p>
    Fórmula:C31H31ClFN3O4
    Cor e Forma:Solid
    Peso molecular:564.05

    Ref: TM-T86503

  • Neflumozide
    Targetmol
    + Info

    Neflumozide

    CAS:
    <p>Neflumozide (HRP 913) is an orally effective derivative of benzisoxazole, characterized by its potent dopamine antagonist properties and antipsychotic activity. It is utilized in research related to psychiatric disorders.</p>
    Fórmula:C22H23FN4O2
    Cor e Forma:Solid
    Peso molecular:394.44

    Ref: TM-T201050

  • 8 Hydroxy PIPAT oxalate
    Targetmol
    + Info

    8 Hydroxy PIPAT oxalate

    CAS:
    <p>8 Hydroxy PIPAT oxalate is a selective 5-HT1A receptor agonist that enhances the spontaneous release of histamine by promoting the degranulation of mast cells in guinea pig and human intestinal preparations. By activating the serotonin signaling pathway, this compound demonstrates potential in regulating gastrointestinal functions and offers insight into the management and suppression of functional gastrointestinal disorders such as irritable bowel syndrome. Its effects in increasing histamine release could play a crucial role in gastrointestinal regulation.</p>
    Fórmula:C18H24INO5
    Cor e Forma:Solid
    Peso molecular:461.29

    Ref: TM-T201052

  • R-96544 hydrochloride
    Targetmol
    + Info

    R-96544 hydrochloride

    CAS:
    <p>5-HT2 receptor antagonist</p>
    Fórmula:C22H29NO3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:355.47

    Ref: TM-T23219

  • Opipramol dihydrochloride
    Targetmol
    + Info

    Opipramol dihydrochloride

    CAS:
    <p>Opipramol (Ensidon) is an atypical tricyclic antidepressant (TCA) primarily functioning as a sigma (σ) receptor agonist. It interacts effectively with sigma recognition sites, having a Ki value of 50 nM. Opipramol is applicable in the study of generalized anxiety disorder (GAD).</p>
    Fórmula:C23H31Cl2N3O
    Cor e Forma:Solid
    Peso molecular:436.418

    Ref: TM-T204660

  • Vibegron
    Targetmol
    + Info

    Vibegron

    CAS:
    <p>Vibegron (MK-4618) is an effective and selective Beta 3 adrenergic receptor agonist, used to treat overactive bladder (OAB).</p>
    Fórmula:C26H28N4O3
    Cor e Forma:Solid
    Peso molecular:444.53

    Ref: TM-T35052

  • Logotipo do CymitQuimica
    Targetmol
    + Info

    5-HT6R/MAO-B modulator 1

    <p>5-HT6R/MAO-B modulator 1 blocks 5-HT6R and permanently inhibits MAO-B, protects glial cells, and reverses memory loss.</p>
    Fórmula:C33H38N4O3S
    Cor e Forma:Solid
    Peso molecular:570.74

    Ref: TM-T64036

  • PSB 36
    Targetmol
    + Info

    PSB 36

    CAS:
    <p>A1 adenosine receptor antagonist</p>
    Fórmula:C21H30N4O3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:386.49

    Ref: TM-T23202

  • Gemilukast
    Targetmol
    + Info

    Gemilukast

    CAS:
    <p>Gemilukast (ONO-6950) is a cysteinyl leukotriene 1 and 2 receptor inhibitor that inhibits bronchoconstriction and is used in the treatment of asthma.</p>
    Fórmula:C36H37F2NO5
    Pureza:98.27% - 99.5%
    Cor e Forma:Solid
    Peso molecular:601.68

    Ref: TM-T11388

  • Serotonin maleate
    Targetmol
    + Info

    Serotonin maleate

    CAS:
    <p>Serotonin hydrogen maleate serves as a monoaminergic neurotransmitter and an endogenous 5-HT receptor agonist within the central nervous system (CNS). It also functions as an inhibitor of catechol O-methyltransferase (COMT), exhibiting a Ki value of 44 μM.</p>
    Fórmula:C14H16N2O5
    Cor e Forma:Solid
    Peso molecular:292.287

    Ref: TM-T204388

  • MRS2905 trisodium
    Targetmol
    + Info

    MRS2905 trisodium

    CAS:
    <p>MRS2905 (α,β-Methylene-2-thio-UDP) trisodium is a selective P2Y14R agonist with an EC50 of 0.92 nM. It shows no activity on UDP-activated P2Y6 receptors or other P2Y receptors.</p>
    Fórmula:C10H13N2Na3O10P2S
    Cor e Forma:Solid
    Peso molecular:484.199

    Ref: TM-T204687